triiodothyronine--reverse has been researched along with Myxedema* in 4 studies
4 other study(ies) available for triiodothyronine--reverse and Myxedema
Article | Year |
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Thyroid hormones in generalized scleroderma. A controlled study.
Parameters of thyroid metabolism were analysed in 42 patients with generalized scleroderma and healthy individuals matched with respect to sex and age for comparison. Decreased free thyroxine (p less than 0.01), decreased free triiodothyronine (p less than 0.001), and increased thyroid-stimulating hormone (p less than 0.001) evidenced an associated state of myxoedema in scleroderma. Total thyroxine was normal, and total triiodothyronine was increased (p less than 0.01) probably reflecting binding to abnormal serum proteins in scleroderma. Normal concentrations of reverse triiodothyronine indicated a normal peripheral metabolism of thyroid hormones. Thyroid-stimulating immunoglobulins also analysed were within normal range. Changes in free thyroxine, free triiodothyronine, and thyroid-stimulating hormone were quantitatively small with mean values within normal ranges. In conclusion, this study evidenced a mild associating myxoedema state in generalized scleroderma. Probably, this reflected slight and subclinical affection of the thyroid. Topics: Adolescent; Adult; Aged; Female; Humans; Immunoglobulin G; Immunoglobulins, Thyroid-Stimulating; Male; Middle Aged; Myxedema; Scleroderma, Systemic; Thyroid Gland; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1986 |
Measurement of thyroxine conversion to triiodothyronine using human lymphocytes. A useful and simple laboratory technique.
The deiodination of T4 to T3 has been studied after incubation of whole lymphocytes with different T4 concentrations, followed by a T3 radioimmunological determination performed on unextracted samples. The lymphocytes were isolated from blood from normal volunteers of both sexes and different age classes as well as from myxedematous subjects and patients with low T3 syndrome. The T3 production, in normal subjects, expressed as pmol/10.10(6) cells was 0.41 +/- 0.75 (T4 = 4.10(-7) M, n = 12), 1.43 +/- 0.14 (T4 = 4.10(-6) M, n = 26) and 1.65 +/- 0.29 (T4 = 8.10(-6) M, n = 11). There was no sex or age-related difference. In 3 myxedematous patients the T3 production was lower than the corresponding value obtained in normal subjects. The T3 production in patients with low T3 syndrome was lower than in controls (p less than 0.001); an inverse correlation was found between the T3 production and the serum rT3 levels, whereas no correlation could be found with serum T3 levels. Topics: Adult; Aged; Female; Humans; Lymphocytes; Male; Myxedema; Radioimmunoassay; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1983 |
Somatostatin and the 24 h levels of serum TSH, T3, T4, and reverse T3 in normals, diabetics and patients treated for myxoedema.
Topics: Adult; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Humans; Insulin; Male; Middle Aged; Myxedema; Somatostatin; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1980 |
Serum T4, T3 and reverse T3 during treatment with propranolol in hyperthyroidism, L-T4 treated myxedema and in normal man.
Serum concentrations of T4, T3 and reverse T3 were studied in two hyperthyroid groups (n = 13 and 11), in a group of normals (n = 9) and in a group of L-T4 substituted patients (n = 7) with severe pretreatment hypothyroidism. Serum T4 did not change except in one of the hyperthyroid groups change to in which a slight decrease was found. In all groups a significant fall in serum T3 and a significant rise in serum reverse T3 were found. An expected increase in serum TSH in the normal and in the L-T4 substituted groups could not be demonstrated. Topics: Adult; Female; Humans; Hyperthyroidism; Male; Middle Aged; Myxedema; Propranolol; Stereoisomerism; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1979 |