triiodothyronine--reverse and Hemangioma

triiodothyronine--reverse has been researched along with Hemangioma* in 2 studies

Other Studies

2 other study(ies) available for triiodothyronine--reverse and Hemangioma

ArticleYear
Advantages of monitoring rT3 and dividing LT3 dose in the treatment of consumptive hypothyroidism associated with infantile hepatic hemangioma.
    Journal of pediatric endocrinology & metabolism : JPEM, 2022, Nov-25, Volume: 35, Issue:11

    In consumptive hypothyroidism associated with infantile hepatic hemangiomas (IHH), elevated reverse triiodothyronine (rT3) is known due to elevated D3. This report shows that rT3 is a new indicator of IHH progression and that three divided doses of LT3 per day were more effective than a single dose.. A 23 day-old boy was diagnosed with diffuse IHH and severe hypothyroidism with high rT3. Propranolol and LT4 were administered. Hemangiomas gradually diminished and rT3 decreased, but the thyroid-stimulating hormone remained elevated, and free triiodothyronine (fT3) did not normalize after 2 weeks of treatment. Liothyronine (LT3) was started as a single dose and then divided into three doses after 1 week, which stabilized thyroid function.. rT3 levels were less variable and decreased in conjunction with tumor shrinkage; thus, rT3 is an indicator of therapeutic outcomes for IHH. LT3 administered in divided doses aided in managing IHH-associated hypothyroidism.

    Topics: Hemangioma; Humans; Hypothyroidism; Liver Neoplasms; Male; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

2022
Use of combined liothyronine and thyroxine therapy for consumptive hypothyroidism associated with hepatic haemangiomas in infancy.
    Hormone research in paediatrics, 2010, Volume: 74, Issue:2

    Hepatic haemiangiomas in infancy are rare. An association with hypothyroidism has been previously reported and is believed to be secondary to the conversion of thyroxine (fT4) to biologically inactive reverse triiodothyronine (rT3) by type 3 iodothyronine deiodinase (D3). We report a case that responded well to the combined use of liothyronine and thyroxine therapy.

    Topics: Hemangioma; Humans; Hypothyroidism; Infant; Iodide Peroxidase; Liver Neoplasms; Male; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

2010