trihexyphenidyl has been researched along with Tremor in 42 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of the anti-parkinsonian drug trihexyphenidyl (THP) to treat patients with Parkinson's disease (PD), particularly those with tremor-dominant PD (tdPD), has been well documented." | 8.12 | Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study. ( Hao, X; Li, T; Liang, Z; Liu, W; Lu, R; Pu, L; Wang, HY, 2022) |
| "Rats given a tremorigenic dose of DDT (75 mg/kg, PO) were treated with pharmacological agents either 30 min prior to DDT or 1-2 h prior to testing at the time of peak effect (12 h postdosing)." | 7.67 | DDT-induced tremor in rats: effects of pharmacological agents. ( Herr, DW; Hong, JS; Tilson, HA, 1985) |
| "An electromyographic method was used to study the effect of combination therapy with L-dopa and trihexyphenidyl on tremor in thirty patients suffering from extrapyramidal motor system disease." | 7.66 | Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor. ( Hökendorf, H, 1979) |
| "The effect of long-acting propranolol hydrochloride (160 mg/d), primidone (250 mg at night), and clonazepam (4 mg/d) on the resting, postural, and kinetic component of tremor was investigated in ten parkinsonian patients in a double-blind crossover design." | 5.06 | Adjuvant therapy of parkinsonian tremor. ( Herbster, G; Koller, WC, 1987) |
| "The use of the anti-parkinsonian drug trihexyphenidyl (THP) to treat patients with Parkinson's disease (PD), particularly those with tremor-dominant PD (tdPD), has been well documented." | 4.12 | Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study. ( Hao, X; Li, T; Liang, Z; Liu, W; Lu, R; Pu, L; Wang, HY, 2022) |
| "Rats given a tremorigenic dose of DDT (75 mg/kg, PO) were treated with pharmacological agents either 30 min prior to DDT or 1-2 h prior to testing at the time of peak effect (12 h postdosing)." | 3.67 | DDT-induced tremor in rats: effects of pharmacological agents. ( Herr, DW; Hong, JS; Tilson, HA, 1985) |
| "The relative efficacy of trihexiphenidyl hydrochloride, amantadine hydrochloride, and low-dose carbidopa-levodopa in reducing parkinsonian tremor was investigated using objective techniques." | 3.67 | Pharmacologic treatment of parkinsonian tremor. ( Koller, WC, 1986) |
| "In a patient with the syndrome of crural paresis and homolateral ataxia, administration of trihexyphenidyl resulted in improvement of disabling unilateral ataxia and gross intention tremor." | 3.66 | Improvement of ataxic hemiparesis with trihexyphenidyl. ( Gunderson, CH; Jabbari, B; McBurney, JW, 1983) |
| "An electromyographic method was used to study the effect of combination therapy with L-dopa and trihexyphenidyl on tremor in thirty patients suffering from extrapyramidal motor system disease." | 3.66 | Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor. ( Hökendorf, H, 1979) |
| " Hence we would advise that if for any reason anticholinergic drugs are to be withdrawn in patients receiving a stable dosage of levodopa this must be done slowly." | 2.64 | Levodopa in Parkinsonism: the effects of withdrawal of anticholinergic drugs. ( Hughes, RC; Polgar, JG; Walton, JN; Weightman, D, 1971) |
| "We diagnosed him with Machado-Joseph disease according to the genetic test." | 1.48 | Tremor during orthostatism as the initial symptom of Machado-Joseph disease. ( Kano, T; Matsushima, M; Naganuma, R; Sasaki, H; Sato, C; Shirai, S; Takahashi, I; Yabe, I, 2018) |
| "Paroxysmal exercise-induced dystonia (PED) is a rare, typically idiopathic familial condition, although sporadic and secondary cases have been reported." | 1.32 | Paroxysmal exercise-induced dystonia as a presenting feature of young-onset Parkinson's disease. ( Bhatia, KP; Bozi, M, 2003) |
| " In a between-groups dosing design, five separate groups of rats received vehicle, clozapine 1." | 1.30 | Similarities and differences between the subchronic and withdrawal effects of clozapine and olanzapine on forelimb force steadiness. ( Fowler, SC; Stanford, JA, 1997) |
| "Primary writing tremor is induced by a specific motor activity, generally the handwriting." | 1.29 | [Writing tremor: report of a case]. ( Nicaretta, DH; Pereira, JS; Pimentel, ML, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (76.19) | 18.7374 |
| 1990's | 4 (9.52) | 18.2507 |
| 2000's | 2 (4.76) | 29.6817 |
| 2010's | 2 (4.76) | 24.3611 |
| 2020's | 2 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, HY | 3 |
| Hao, X | 3 |
| Lu, R | 3 |
| Li, T | 3 |
| Pu, L | 3 |
| Liu, W | 3 |
| Liang, Z | 3 |
| Sahoo, LK | 1 |
| Holla, VV | 1 |
| Batra, D | 1 |
| Prasad, S | 1 |
| Bhattacharya, A | 1 |
| Kamble, N | 1 |
| Yadav, R | 1 |
| Pal, PK | 1 |
| Shirai, S | 1 |
| Yabe, I | 1 |
| Naganuma, R | 1 |
| Sato, C | 1 |
| Takahashi, I | 1 |
| Matsushima, M | 1 |
| Kano, T | 1 |
| Sasaki, H | 1 |
| Iha, HA | 1 |
| Kunisawa, N | 1 |
| Shimizu, S | 1 |
| Onishi, M | 1 |
| Nomura, Y | 1 |
| Matsubara, N | 1 |
| Iwai, C | 1 |
| Ogawa, M | 1 |
| Hashimura, M | 1 |
| Sato, K | 1 |
| Kato, M | 1 |
| Ohno, Y | 1 |
| BRUMLIK, J | 1 |
| CANTER, G | 1 |
| DELATORRE, R | 1 |
| MIER, M | 1 |
| PETROVICK, M | 1 |
| BOSHES, B | 1 |
| LESLIE, GB | 1 |
| MAXWELL, DR | 1 |
| Bozi, M | 1 |
| Bhatia, KP | 1 |
| Walther, H | 2 |
| Jabbari, B | 1 |
| Gunderson, CH | 1 |
| McBurney, JW | 1 |
| Chaudhuri, SK | 1 |
| Cousse, H | 1 |
| Mouzin, G | 1 |
| Bonnaud, B | 1 |
| Charveron, M | 1 |
| Stenger, A | 1 |
| Morre, M | 1 |
| Lauressergues, H | 1 |
| Linazasoro, G | 1 |
| Nicaretta, DH | 1 |
| Pereira, JS | 1 |
| Pimentel, ML | 1 |
| Felice, KJ | 1 |
| Grunnet, ML | 1 |
| Stanford, JA | 1 |
| Fowler, SC | 1 |
| DiMario, FJ | 1 |
| Hökendorf, H | 1 |
| Agnoli, A | 3 |
| Ruggieri, S | 3 |
| Denaro, A | 1 |
| Lelli, A | 1 |
| Butzer, JF | 1 |
| Silver, DE | 1 |
| Sahs, AL | 1 |
| Herr, DW | 2 |
| Hong, JS | 2 |
| Chen, P | 1 |
| Tilson, HA | 2 |
| Harry, GJ | 1 |
| Koller, WC | 3 |
| Herbster, G | 1 |
| Rubino, FA | 1 |
| Casacchia, M | 2 |
| Volante, F | 2 |
| Accornero, N | 2 |
| Birket-Smith, E | 1 |
| Omori, K | 1 |
| Kojima, T | 1 |
| Oelszner, W | 1 |
| Wagner, U | 1 |
| Petelin, LS | 1 |
| Rodríguez, R | 1 |
| Blonsky, ER | 1 |
| Ericsson, AD | 1 |
| McKinney, AS | 1 |
| Rix, A | 1 |
| Wang, RI | 1 |
| Rimm, AA | 1 |
| Sevitt, I | 1 |
| Hitomi, M | 1 |
| Kumadaki, N | 1 |
| Furukawa, T | 1 |
| Ito, N | 1 |
| Sato, Y | 1 |
| Kumada, S | 1 |
| Sethy, VH | 1 |
| Van Woert, MH | 1 |
| Chase, TN | 1 |
| Woods, AC | 1 |
| Glaubiger, GA | 1 |
| Ursillo, RC | 1 |
| McCulloch, JA | 1 |
| Frances, H | 1 |
| Jacob, J | 1 |
| Hughes, RC | 1 |
| Polgar, JG | 1 |
| Weightman, D | 1 |
| Walton, JN | 1 |
| Stern, M | 1 |
| Roffwarg, H | 1 |
| Duvoisin, R | 1 |
| Dandiya, PC | 1 |
| Bhargava, LP | 1 |
| Masák, S | 1 |
| Metys, J | 1 |
| Votava, Z | 1 |
6 trials available for trihexyphenidyl and Tremor
| Article | Year |
|---|---|
Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up.
Topics: Activities of Daily Living; Aged; Amantadine; Benztropine; Clinical Trials as Topic; Diphenhydramine | 1975 |
Adjuvant therapy of parkinsonian tremor.
Topics: Aged; Antiparkinson Agents; Carbidopa; Clonazepam; Double-Blind Method; Drug Therapy, Combination; H | 1987 |
Phase II multiclinic study of elantrine in parkinsonism.
Topics: Aged; Antiparkinson Agents; Clinical Trials as Topic; Dibenzazepines; Dimethylamines; Female; Humans | 1974 |
A comparison of propranolol and benzhexol in essential tremor.
Topics: Aged; Clinical Trials as Topic; Diarrhea; Female; Handwriting; Humans; Male; Middle Aged; Nausea; Pr | 1974 |
Parkinson disease treated with a suspected dopamine receptor agonist.
Topics: Adult; Aged; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Dihydroxyphenyla | 1974 |
Levodopa in Parkinsonism: the effects of withdrawal of anticholinergic drugs.
Topics: Dihydroxyphenylalanine; Drug Synergism; Drug Tolerance; Female; Humans; Male; Methods; Neurologic Ma | 1971 |
36 other studies available for trihexyphenidyl and Tremor
| Article | Year |
|---|---|
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Comparison of effectiveness of trihexyphenidyl and levodopa on motor symptoms in Parkinson's disease.
Topics: Antiparkinson Agents; Humans; Hypokinesia; Infant, Newborn; Levodopa; Parkinson Disease; Treatment O | 2020 |
Tremor during orthostatism as the initial symptom of Machado-Joseph disease.
Topics: Clonazepam; Electromyography; Humans; Machado-Joseph Disease; Male; Middle Aged; Pedigree; Treatment | 2018 |
Mechanism Underlying Organophosphate Paraoxon-Induced Kinetic Tremor.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Gene Expression; Male; M | 2019 |
A CRITICAL ANALYSIS OF THE EFFECTS OF TRIHEXYPHENIDYL (ARTANE) ON THE COMPONENTS OF THE PARKINSONIAN SYNDROME.
Topics: Gait; Geriatrics; Humans; Parkinsonian Disorders; Physiology; Placebos; Psychological Tests; Respira | 1964 |
INHIBITION OF TREMORINE BY A GROUP OF NON-ANTI-PARKINSON PHENOTHIAZINE DERIVATIVES.
Topics: Antipsychotic Agents; Atropine; Benactyzine; Chlorpromazine; Histamine H1 Antagonists; Mice; Muscle | 1964 |
Paroxysmal exercise-induced dystonia as a presenting feature of young-onset Parkinson's disease.
Topics: Adult; Age Factors; Antiparkinson Agents; Basal Ganglia; Diagnosis, Differential; Dopamine Plasma Me | 2003 |
[Pharmacologic studies of the strychnine tremor in infantile mice].
Topics: Animals; Animals, Newborn; Anticonvulsants; Atropine; Benactyzine; Diphenhydramine; Electromyography | 1967 |
Improvement of ataxic hemiparesis with trihexyphenidyl.
Topics: Adult; Ataxia; Brain Diseases; Extremities; Hemiplegia; Humans; Male; Radiography; Tremor; Trihexyph | 1983 |
Anticholinergic agents on neuromuscular and tremorogenic action of harmine.
Topics: Alkaloids; Animals; Atropine; Female; Harmine; Male; Neuromuscular Junction; Rats; Tremor; Trihexyph | 1980 |
[Phenothiazine carboxamides that have anticholinergic properties].
Topics: Animals; Behavior, Animal; Convulsants; Dogs; Mice; Nicotine; Parasympatholytics; Pentylenetetrazole | 1980 |
Anticholinergics and dyskinesia.
Topics: Aged; Biperiden; Carbidopa; Drug Combinations; Drug Therapy, Combination; Dyskinesia, Drug-Induced; | 1994 |
[Writing tremor: report of a case].
Topics: Aged; Handwriting; Humans; Male; Tremor; Trihexyphenidyl | 1994 |
Inclusion body myositis associated with a severe unilateral levodopa-responsive upper extremity tremor.
Topics: Action Potentials; Anti-Dyskinesia Agents; Brain Neoplasms; Electromyography; Hand; Humans; Inclusio | 1996 |
Similarities and differences between the subchronic and withdrawal effects of clozapine and olanzapine on forelimb force steadiness.
Topics: Animals; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Clozapine; | 1997 |
Childhood head tremor.
Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Male; | 2000 |
Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor.
Topics: Aged; Basal Ganglia Diseases; Drug Therapy, Combination; Electromyography; Female; Humans; Levodopa; | 1979 |
Parkinson's disease improvement after the addition of levodopa-carbidopa to anticholinergic treatment. An open controlled study.
Topics: Administration, Oral; Adult; Aged; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Female; Hu | 1978 |
Pharmacological modification of DDT-induced tremor and hyperthermia in rats: distributional factors.
Topics: Animals; Brain Chemistry; DDT; Drug Interactions; Fever; Hydantoins; Male; Piperonyl Butoxide; Rats; | 1986 |
DDT-induced tremor in rats: effects of pharmacological agents.
Topics: Analysis of Variance; Animals; DDT; Dose-Response Relationship, Drug; Male; Mephenesin; Phenytoin; P | 1985 |
Pharmacologic treatment of parkinsonian tremor.
Topics: Amantadine; Carbidopa; Drug Combinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Tr | 1986 |
Combined resting-postural tremors.
Topics: Aged; Ethanol; Female; Humans; Levodopa; Male; Middle Aged; Posture; Propranolol; Rest; Tremor; Trih | 1985 |
Parkinson's tremor, relief by an antiaminic drug (BC 105). Discussion on the biochemical pathogenesis of Parkinsonian tremor.
Topics: Adult; Aged; Benzocycloheptenes; Dihydroxyphenylalanine; Ergolines; Female; Histamine H1 Antagonists | 1972 |
Abnormal involuntary movements induced by anticholinergic therapy.
Topics: Aged; Biperiden; Dibenzazepines; Female; Humans; Mastication; Middle Aged; Movement Disorders; Orphe | 1974 |
Effect of L-5HTP on tremorine- or oxotremorine-induced tremor in mice and rats.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Drug Synergism; Fenclonine; Male; Mice; Oxotremorine; Rats; | 1973 |
[Experimental testing of some piperidine propanol diastereomers in animals as potential parkinsonism drugs].
Topics: 1-Propanol; Animals; Central Nervous System; Ileum; Mice; Organ Culture Techniques; Parasympatholyti | 1971 |
[Tremulous hyperkinesia].
Topics: Adult; Cerebellum; Electrokymography; Female; Ganglionic Blockers; Histamine H1 Antagonists; Humans; | 1969 |
Antagonism of tremorine-induced tremor by serotoninergic agents in mice. Interactions with levodopa.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Benztropine; Dihydroxyphenylalanine; Dose-Response Relations | 1972 |
Pharmacological study of piroheptine, a new antiparkinson drug, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-ethyl-2-methylpyrrolidine. I. Effects on drug-induced tremor and catatonia, and on adrenergic actions.
Topics: Animals; Antiparkinson Agents; Atropine; Avoidance Learning; Catatonia; Cats; Conditioning, Psycholo | 1972 |
Antimuscarinic drugs--effect on brain acetylcholine and tremors in rats.
Topics: Acetylcholine; Animals; Atropine; Benztropine; Brain Chemistry; Depression, Chemical; Drug Interacti | 1973 |
The effect of elantrine, a new anti-Parkinsonism agent, on drug-induced tremor in mice.
Topics: Alkaloids; Animals; Antiparkinson Agents; Atropine; Benztropine; Body Temperature; Central Nervous S | 1972 |
[Comparison of the effects of cholinergic and anticholinergic substances on the cerebral content of acetylcholine and on the motility of mice].
Topics: Acetylcholine; Amphetamine; Animals; Atropine; Benactyzine; Brain Chemistry; Glycolates; Imipramine; | 1971 |
[Action of amantadine on parkinsonian tremor].
Topics: Adult; Aged; Amantadine; Ergolines; Female; Humans; Male; Middle Aged; Parkinson Disease; Promethazi | 1971 |
The parkinsonian tremor in sleep.
Topics: Aged; Electroencephalography; Eye Movements; Female; Humans; Male; Middle Aged; Movement; Parkinson | 1968 |
The antiparkinsonian activity of monoamine oxidase inhibitors and other agents in rats and mice.
Topics: Animals; Dextroamphetamine; Diphenhydramine; Imipramine; Iproniazid; Isocarboxazid; Mice; Monoamine | 1968 |
Antagonism of benactyzine, trihexyphenidyl and three antidepressants against arecoline and Tremorine-induced "analgesia", tremor and discoordination in mice.
Topics: Analgesia; Animals; Antidepressive Agents; Benactyzine; Drug Incompatibility; Mice; Motor Neurons; T | 1965 |