trihexyphenidyl has been researched along with Poisoning in 4 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The influence of the pharmacological prophylaxis with Panpal (pyridostigmine in combination with benaetyzine and trihexyphenidyle) on acetylcholinesterase activity in diaphragm and various parts of brain at 1 and 3 h following non-treated and treated (the oxime HI-6 in combination with atropine) soman poisoning was tested on male rats." | 7.70 | [The effect of pharmacologic prophylaxis with Panpal on acetylcholinesterase activity in the diaphragm and various parts of the brain in rats during treated and untreated Soman poisoning]. ( Kassa, J, 1998) |
| " PANPAL pretreatment did not improve the efficacy of HI-6 in combination with benactyzine on soman-induced anticholinesterase and stressogenic effects." | 5.29 | The influence of pharmacological pretreatment on efficacy of HI-6 oxime in combination with benactyzine in soman poisoning in rats. ( Bajgar, J; Kassa, J, 1996) |
| "The influence of the pharmacological prophylaxis with Panpal (pyridostigmine in combination with benaetyzine and trihexyphenidyle) on acetylcholinesterase activity in diaphragm and various parts of brain at 1 and 3 h following non-treated and treated (the oxime HI-6 in combination with atropine) soman poisoning was tested on male rats." | 3.70 | [The effect of pharmacologic prophylaxis with Panpal on acetylcholinesterase activity in the diaphragm and various parts of the brain in rats during treated and untreated Soman poisoning]. ( Kassa, J, 1998) |
| " Pyridostigmine peroral pretreatment followed by intramuscular postpoisoning therapy with atropine, obidoxime and/or trimedoxime, and diazepam protected mice against the lethal action of soman." | 3.68 | Efficacy of various pretreatment and therapy regimens against soman lethality in mice. ( Bajgar, J; Fusek, J; Jakl, A; Patocka, J, 1991) |
| " PANPAL pretreatment did not improve the efficacy of HI-6 in combination with benactyzine on soman-induced anticholinesterase and stressogenic effects." | 1.29 | The influence of pharmacological pretreatment on efficacy of HI-6 oxime in combination with benactyzine in soman poisoning in rats. ( Bajgar, J; Kassa, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kassa, J | 2 |
| Bajgar, J | 2 |
| Lennox, WJ | 1 |
| Harris, LW | 1 |
| Anderson, DR | 1 |
| Solana, RP | 1 |
| Murrow, ML | 1 |
| Wade, JV | 1 |
| Patocka, J | 1 |
| Jakl, A | 1 |
| Fusek, J | 1 |
4 other studies available for trihexyphenidyl and Poisoning
| Article | Year |
|---|---|
The influence of pharmacological pretreatment on efficacy of HI-6 oxime in combination with benactyzine in soman poisoning in rats.
Topics: Animals; Antidotes; Benactyzine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Chol | 1996 |
[The effect of pharmacologic prophylaxis with Panpal on acetylcholinesterase activity in the diaphragm and various parts of the brain in rats during treated and untreated Soman poisoning].
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Benactyzine; Brain; Chemical Warfare Agents; Cho | 1998 |
Successful pretreatment/therapy of soman, sarin and VX intoxication.
Topics: Animals; Cholinesterase Inhibitors; Female; Guinea Pigs; Lethal Dose 50; Male; Organothiophosphorus | 1992 |
Efficacy of various pretreatment and therapy regimens against soman lethality in mice.
Topics: Animals; Atropine; Diazepam; Female; Male; Mice; Obidoxime Chloride; Poisoning; Pyridostigmine Bromi | 1991 |