Compounds > trihexyphenidyl
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trihexyphenidyl and Parkinsonian Disorders

trihexyphenidyl has been researched along with Parkinsonian Disorders in 50 studies

Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.

Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.

Research Excerpts

ExcerptRelevanceReference
"DYT16 is an autosomal recessive dystonia-parkinsonism due to putative mutations at PRKRA gene."1.38DYT16: the original cases. ( Camargos, S; Cardoso, F; Lees, AJ; Singleton, A, 2012)
"A 41 year old man with parkinsonism and pyramidal signs is described."1.31Anticholinergic drugs: response of parkinsonism not responsive to levodopa. ( Kuroiwa, Y; Momose, T; Okada, M; Yamada, H, 2002)
"The most disabling form of Parkinsonism is that occurring after encephalitis."1.23Therapy of Parkinson's disease. ( VAN METER, JR, 1950)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199047 (94.00)18.7374
1990's0 (0.00)18.2507
2000's2 (4.00)29.6817
2010's1 (2.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Camargos, S1
Lees, AJ1
Singleton, A1
Cardoso, F1
DOSHAY, LJ3
CONSTABLE, K3
ZIER, A2
KAPLAN, HA1
MACHOVER, S1
RABINER, A1
DE MAAR, EW1
VON KEYSERLINGK, H1
PORTEOUS, HB1
ROSS, DN1
BERGER, H2
KIRCHHOF, JK2
RASHKIS, HA1
SMARR, ER1
NAHUNEK, K1
RYBAKOVA, V1
KONCHEGUL, L1
O'DOHERTY, DS1
COOPER, IS1
PAKKENBERG, H1
POLEZHAEVA, AI1
WALKER, LG1
HIEBERT, T1
SMYTH, NP1
GILLINGHAM, FJ1
KALYANARAMAN, S1
TURNER, JW1
BURNS, BD1
DEJONG, D1
SOLIS-QUIROGA, OH1
BRUMLIK, J1
CANTER, G1
DELATORRE, R1
MIER, M1
PETROVICK, M1
BOSHES, B1
STJEAN, A1
DONALD, M1
BAN, TA1
MEYER, JS1
MAGEE, KR1
STRANG, RR2
MILLER, V1
DRAPER, IT1
JOHNS, RJ1
SILVERSIDES, JL1
RICHARDSON, JC1
MALONE, MH1
ARZT, FC1
BRAGAN, RA1
DECATO, L1
VAN METER, JR1
GARAI, O1
GALLAGHER, DJ1
PALMER, H1
GOEBEL, U1
VOLLMER, H1
HAGLUND, G1
EFFRON, AS1
FARQUHAR, JW1
ALONSO FERNANDEZ, F1
CANELIS, M1
FARNELL, FJ1
McGAVACK, TH1
ELLENBOGEN, BK1
HARRIS, TH1
TORRENS, JK1
REMOUCHAMPS, L1
VERBEKE, R1
Chan, KH1
Cheung, RT1
Au-Yeung, KM1
Mak, W1
Cheng, TS1
Ho, SL1
Fann, WE1
Lake, CR1
CORBIN, KB1
SCHWAB, RS1
TILLMANN, WR1
DOW, RS1
ROSENBAUM, H1
Yamada, H1
Momose, T1
Okada, M1
Kuroiwa, Y1

Reviews

1 review available for trihexyphenidyl and Parkinsonian Disorders

ArticleYear
CURRENT VIEWS CONCERNING THE ETIOLOGY, PATHOPHYSIOLOGY, AND TREATMENT OF PARKINSON'S DISEASE.
    Journal of neuropsychiatry, 1964, Volume: 5

    Topics: Classification; Drug Therapy; Muscle Relaxants, Central; Neurosurgery; Neurosurgical Procedures; Par

1964

Trials

1 trial available for trihexyphenidyl and Parkinsonian Disorders

ArticleYear
On the coexistence of parkinsonism and tardive dyskinesia.
    Diseases of the nervous system, 1974, Volume: 35, Issue:7

    Topics: Amantadine; Antiparkinson Agents; Cross-Over Studies; Double-Blind Method; Dyskinesia, Drug-Induced;

1974

Other Studies

48 other studies available for trihexyphenidyl and Parkinsonian Disorders

ArticleYear
DYT16: the original cases.
    Journal of neurology, neurosurgery, and psychiatry, 2012, Volume: 83, Issue:10

    Topics: Adolescent; Adult; Age of Onset; Anti-Dyskinesia Agents; Antiparkinson Agents; Baclofen; Biperiden;

2012
Five year follow-up of artane treatment; the outcomes in 461 Parkinson cases.
    Transactions of the American Neurological Association, 1953, Volume: 3, Issue:78th Meeti

    Topics: Follow-Up Studies; Humans; Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl

1953
A study of the effectiveness of drug therapy in parkinsonism.
    The Journal of nervous and mental disease, 1954, Volume: 119, Issue:5

    Topics: Humans; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; Placebos; Scopolamine;

1954
[Pharmacokinetics in parkinsonism].
    Geneeskundige gids, 1955, Aug-18, Volume: 33, Issue:17

    Topics: Anticonvulsants; Antipsychotic Agents; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Di

1955
[P 119, a spasmolytic for the treatment of parkinsonism].
    Das Deutsche Gesundheitswesen, 1955, Oct-13, Volume: 10, Issue:41

    Topics: Parasympatholytics; Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl

1955
Mental symptoms in parkinsonism following benzhexol hydrochloride therapy.
    British medical journal, 1956, Jul-21, Volume: 2, Issue:4985

    Topics: Humans; Mental Disorders; Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl

1956
Parkinsonism: treatment with curare.
    Annals of internal medicine, 1956, Volume: 45, Issue:5

    Topics: Cardiovascular Agents; Curare; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders;

1956
Parkinsonism: treatment with curare.
    Annals of internal medicine, 1956, Volume: 45, Issue:5

    Topics: Cardiovascular Agents; Curare; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders;

1956
Parkinsonism: treatment with curare.
    Annals of internal medicine, 1956, Volume: 45, Issue:5

    Topics: Cardiovascular Agents; Curare; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders;

1956
Parkinsonism: treatment with curare.
    Annals of internal medicine, 1956, Volume: 45, Issue:5

    Topics: Cardiovascular Agents; Curare; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders;

1956
[Study of combined therapy of parkinsonian conditions, especially postencephalitic conditions].
    Der Nervenarzt, 1956, Oct-20, Volume: 27, Issue:10

    Topics: Autonomic Agents; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; Trihexypheni

1956
[Study of combined therapy of parkinsonian conditions, especially postencephalitic conditions].
    Der Nervenarzt, 1956, Oct-20, Volume: 27, Issue:10

    Topics: Autonomic Agents; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; Trihexypheni

1956
[Study of combined therapy of parkinsonian conditions, especially postencephalitic conditions].
    Der Nervenarzt, 1956, Oct-20, Volume: 27, Issue:10

    Topics: Autonomic Agents; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; Trihexypheni

1956
[Study of combined therapy of parkinsonian conditions, especially postencephalitic conditions].
    Der Nervenarzt, 1956, Oct-20, Volume: 27, Issue:10

    Topics: Autonomic Agents; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; Trihexypheni

1956
Protection against reserpine-induced Parkinsonism.
    The American journal of psychiatry, 1957, Volume: 113, Issue:12

    Topics: Humans; Parkinson Disease; Parkinsonian Disorders; Reserpine; Trihexyphenidyl

1957
Procyclidine hydrochloride (kemadrin) treatment of parkinsonism; result in 108 patients.
    Neurology, 1957, Volume: 7, Issue:7

    Topics: Parkinson Disease; Parkinsonian Disorders; Procyclidine; Trihexyphenidyl

1957
[Parkinsonism-like symptoms caused by chlorpromazine therapy].
    Ceskoslovenska psychiatrie, 1958, Volume: 54, Issue:3

    Topics: Chlorpromazine; Electroconvulsive Therapy; Humans; Parkinson Disease; Parkinsonian Disorders; Psycho

1958
The use of kemadrin in the treatment of drug-induced parkinsonism; preliminary report.
    The Medical annals of the District of Columbia, 1958, Volume: 27, Issue:8

    Topics: Parkinson Disease; Parkinsonian Disorders; Procyclidine; Trihexyphenidyl

1958
Parkinsonism: drug therapy; neurosurgical therapy.
    Postgraduate medicine, 1958, Volume: 24, Issue:6

    Topics: Cardiovascular Agents; Humans; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders;

1958
[Pathogenesis and medical treatment of parkinsonism].
    Ugeskrift for laeger, 1963, May-24, Volume: 125

    Topics: Humans; Imipramine; Parkinson Disease; Parkinsonian Disorders; Piperidines; Trihexyphenidyl

1963
[Preparations for the treatment of Parkinsonism-cyclodol and ridinol].
    Meditsinskaia promyshlennost' SSSR, 1962, Volume: 10

    Topics: Parasympatholytics; Parkinson Disease; Parkinsonian Disorders; Piperidines; Trihexyphenidyl

1962
Acute suppurative parotitis associated with certain drugs in the treatment of parkinsonism.
    The Medical annals of the District of Columbia, 1962, Volume: 31

    Topics: Humans; Parasympatholytics; Parkinson Disease; Parkinsonian Disorders; Parotitis; Trihexyphenidyl

1962
PARKINSON'S DISEASE.
    Physiotherapy, 1963, Dec-10, Volume: 49

    Topics: Amitriptyline; Dextroamphetamine; Humans; Imipramine; Muscle Relaxants, Central; Neurosurgery; Orphe

1963
PARKINSONISM: AETIOLOGY AND TREATMENT.
    London Clinic medical journal, 1964, Volume: 5

    Topics: Carbon Monoxide Poisoning; Craniocerebral Trauma; Drug Therapy; Encephalitis; Intracranial Arteriosc

1964
EFFECTS OF TRIHEXYPHENIDYL HYDROCHLORIDE (ARTANE) ON PARKINSON'S DISEASE.
    Neurology, 1964, Volume: 14

    Topics: Parkinson Disease; Parkinsonian Disorders; Placebos; Trihexyphenidyl

1964
A CRITICAL ANALYSIS OF THE EFFECTS OF TRIHEXYPHENIDYL (ARTANE) ON THE COMPONENTS OF THE PARKINSONIAN SYNDROME.
    The Journal of nervous and mental disease, 1964, Volume: 138

    Topics: Gait; Geriatrics; Humans; Parkinsonian Disorders; Physiology; Placebos; Psychological Tests; Respira

1964
INTERCHANGEABLITY OF ANTIPARKINSONIAN MEDICATION.
    The American journal of psychiatry, 1964, Volume: 120

    Topics: Antiparkinson Agents; Biomedical Research; Extrapyramidal Tracts; Geriatrics; Humans; Parasympatholy

1964
ORPHENADRINE IN THE TREATMENT OF PARKINSON'S DISEASE.
    Current medicine and drugs, 1964, Volume: 5, Issue:1

    Topics: Biomedical Research; Geriatrics; Orphenadrine; Parkinson Disease; Parkinsonian Disorders; Pharmacolo

1964
THE EFFECTS OF BIPERIDEN HYDROCHLORIDE (AKINETON) IN POST-ENCEPHALITIC PARKINSONISM.
    Scottish medical journal, 1964, Volume: 9

    Topics: Biomedical Research; Biperiden; Drug Therapy; Encephalitis; Parasympatholytics; Parkinson Disease, P

1964
THE DISORDERED MOVEMENT IN PARKINSONISM AND THE EFFECT OF DRUG TREATMENT.
    Bulletin of the Johns Hopkins Hospital, 1964, Volume: 115

    Topics: Atropine; Dextroamphetamine; Diphenhydramine; Drug Therapy; Geriatrics; Humans; Kinetics; Motor Skil

1964
THE PARKINSONIAN SYNDROME. PROGNOSIS AND TREATMENT.
    Postgraduate medicine, 1965, Volume: 37

    Topics: Drug Therapy; Humans; Neurosurgery; Parkinsonian Disorders; Physical Therapy Modalities; Prognosis;

1965
DRUGS FOR PARKINSONISM.
    Canadian Medical Association journal, 1965, Apr-24, Volume: 92

    Topics: Alkaloids; Anti-Allergic Agents; Drug Therapy; Histamine H1 Antagonists; Muscle Relaxants, Central;

1965
A COMPARATIVE STUDY OF TRIHEXYPHENIDYL (ARTANE) AND ORPHENADRINE (DISIPAL) IN THE TREATMENT OF GERIATRIC PARKINSONISM.
    Journal of the American Geriatrics Society, 1965, Volume: 13

    Topics: Biomedical Research; Drug Therapy; Geriatrics; Orphenadrine; Parkinsonian Disorders; Toxicology; Tri

1965
RESERPINE-NICOTINE INDUCED PARKINSONISM IN MICE.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 154

    Topics: Anticonvulsants; Atropine; Lactose; Mice; Muscle Relaxants, Central; Neostigmine; Nicotine; Parkinso

1965
Therapy of Parkinson's disease.
    California medicine, 1950, Volume: 73, Issue:4

    Topics: Diphenhydramine; Encephalitis; Humans; Mephenesin; Muscle Rigidity; Pain; Parkinson Disease; Parkins

1950
Lysivane and artane in the treatment of parkinsonism.
    Lancet (London, England), 1951, Feb-24, Volume: 1, Issue:6652

    Topics: Parkinsonian Disorders; Phenothiazines; Trihexyphenidyl

1951
A comparative study of the use of artane and lysivane in the treatment of parkinsonism.
    The New Zealand medical journal, 1950, Volume: 49, Issue:273

    Topics: Parkinsonian Disorders; Phenothiazines; Trihexyphenidyl

1950
Artane in the treatment of Parkinson's disease.
    Medicine illustrated, 1951, Volume: 5, Issue:5

    Topics: Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl

1951
[Clinical results with artane in parkinsonism and other extrapyramidal syndromes].
    Munchener medizinische Wochenschrift (1950), 1951, May-25, Volume: 93, Issue:21

    Topics: Basal Ganglia Diseases; Extrapyramidal Tracts; Parkinsonian Disorders; Syndrome; Trihexyphenidyl

1951
Pitfalls in evaluating drug therapy of parkinsonism; comparative effects of rabellon and artane.
    New York state journal of medicine, 1951, Aug-15, Volume: 51, Issue:16

    Topics: Parkinsonian Disorders; Trihexyphenidyl

1951
[Artane therapy of parkinsonism].
    Nordisk medicin, 1951, Jul-04, Volume: 46, Issue:27

    Topics: Parkinsonian Disorders; Trihexyphenidyl

1951
How to treat parkinsonism.
    GP, 1951, Volume: 4, Issue:4

    Topics: Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl

1951
Treatment of parkinsonism in a child.
    Lancet (London, England), 1952, Mar-29, Volume: 1, Issue:6709

    Topics: Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl

1952
[First personal impressions on the treatment of the parkinsonian syndrome with artane].
    Medicamenta, 1951, Nov-01, Volume: 9, Issue:208

    Topics: Humans; Parkinson Disease; Parkinsonian Disorders; Social Behavior; Trihexyphenidyl

1951
Clinical experiences in parkinsonism with a new type of antispasmodic, 3-(piperidyl)-1-phenyl-1-cyclohexyl-1-propanol hydrochloride (artane).
    The American journal of the medical sciences, 1949, Volume: 218, Issue:6

    Topics: 1-Propanol; Benzyl Alcohols; Parasympatholytics; Parkinsonian Disorders; Trihexyphenidyl

1949
Artane in the treatment of parkinsonism.
    Lancet (London, England), 1950, Jun-03, Volume: 1, Issue:6614

    Topics: Parkinsonian Disorders; Spasm; Trihexyphenidyl

1950
Use of artane in parkinsonism.
    Texas state journal of medicine, 1950, Volume: 46, Issue:7

    Topics: Parkinsonian Disorders; Trihexyphenidyl

1950
[Treatment of Parkinson's syndrome by trihexylphenidyl (artane)].
    La Presse medicale, 1950, Jul-29, Volume: 58, Issue:48

    Topics: Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl

1950
Wilson's disease with depression and parkinsonism.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2005, Volume: 12, Issue:3

    Topics: Adult; Antiparkinson Agents; Brain; Bromocriptine; Chelating Agents; Depressive Disorder; Female; He

2005
Artane therapy for parkinsonism; a preliminary study of results in 117 cases.
    Journal of the American Medical Association, 1949, Aug-27, Volume: 140, Issue:17

    Topics: Humans; Parkinsonian Disorders; Trihexyphenidyl

1949
Trihexyphenidyl; evaluation of the new agent in the treatment of Parkinsonism.
    Journal of the American Medical Association, 1949, Oct-08, Volume: 141, Issue:6

    Topics: Parkinsonian Disorders; Trihexyphenidyl

1949
Artane in the treatment of Parkinson's disease; a report of its effectiveness alone and in combination with benadryl and parpanit.
    The New England journal of medicine, 1949, Sep-29, Volume: 241, Issue:13

    Topics: Cyclopentanes; Diphenhydramine; Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl

1949
The treatment of Parkinsonism with artane.
    Northwest medicine, 1949, Volume: 48, Issue:10

    Topics: Parkinsonian Disorders; Trihexyphenidyl

1949
Anticholinergic drugs: response of parkinsonism not responsive to levodopa.
    Journal of neurology, neurosurgery, and psychiatry, 2002, Volume: 72, Issue:1

    Topics: Adult; Brain Mapping; Cholinergic Antagonists; Corpus Striatum; Humans; Levodopa; Magnetic Resonance

2002