trihexyphenidyl has been researched along with Parkinson Disease in 172 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of the anti-parkinsonian drug trihexyphenidyl (THP) to treat patients with Parkinson's disease (PD), particularly those with tremor-dominant PD (tdPD), has been well documented." | 8.12 | Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study. ( Hao, X; Li, T; Liang, Z; Liu, W; Lu, R; Pu, L; Wang, HY, 2022) |
| "We report a 71-year-old woman with tactile hallucinations induced by trihexyphenidyl." | 7.73 | [Tactile hallucinations induced by trihexyphenidyl in a patient with Parkinson's disease]. ( Funakawa, I; Jinnai, K, 2005) |
| "A 55-year-old man with idiopathic Parkinson's disease developed myasthenia gravis shortly after taking trihexyphenidyl." | 7.67 | Parkinson's disease and myasthenia gravis: adverse effect of trihexyphenidyl on neuromuscular transmission. ( Hazama, T; Kajiyama, K; Okahisa, N; Takahashi, M; Tarui, S; Ueno, S; Yorifuji, S, 1987) |
| "An electromyographic method was used to study the effect of combination therapy with L-dopa and trihexyphenidyl on tremor in thirty patients suffering from extrapyramidal motor system disease." | 7.66 | Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor. ( Hökendorf, H, 1979) |
| "However, pneumonia combined with malignant hyperthermia and SIADH has rarely been reported." | 5.56 | Trihexyphenidyl induced malignant hyperthermia in a patient with Parkinson's disease complicated with pneumonia: A case report. ( Chen, Y; Feng, C; Kang, Y; Liu, F; Ma, W; Xu, G; Zhao, J, 2020) |
| "The effect of long-acting propranolol hydrochloride (160 mg/d), primidone (250 mg at night), and clonazepam (4 mg/d) on the resting, postural, and kinetic component of tremor was investigated in ten parkinsonian patients in a double-blind crossover design." | 5.06 | Adjuvant therapy of parkinsonian tremor. ( Herbster, G; Koller, WC, 1987) |
| "The use of the anti-parkinsonian drug trihexyphenidyl (THP) to treat patients with Parkinson's disease (PD), particularly those with tremor-dominant PD (tdPD), has been well documented." | 4.12 | Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study. ( Hao, X; Li, T; Liang, Z; Liu, W; Lu, R; Pu, L; Wang, HY, 2022) |
| "We report a 71-year-old woman with tactile hallucinations induced by trihexyphenidyl." | 3.73 | [Tactile hallucinations induced by trihexyphenidyl in a patient with Parkinson's disease]. ( Funakawa, I; Jinnai, K, 2005) |
| " In this study the anticholinergic drug, trihexyphenidyl, at low doses when administered chronically for one month to Parkinson disease patients caused a decrease in performance on recent but not immediate memory tests." | 3.67 | Disturbance of recent memory function in parkinsonian patients on anticholinergic therapy. ( Koller, WC, 1984) |
| "A 55-year-old man with idiopathic Parkinson's disease developed myasthenia gravis shortly after taking trihexyphenidyl." | 3.67 | Parkinson's disease and myasthenia gravis: adverse effect of trihexyphenidyl on neuromuscular transmission. ( Hazama, T; Kajiyama, K; Okahisa, N; Takahashi, M; Tarui, S; Ueno, S; Yorifuji, S, 1987) |
| "The relative efficacy of trihexiphenidyl hydrochloride, amantadine hydrochloride, and low-dose carbidopa-levodopa in reducing parkinsonian tremor was investigated using objective techniques." | 3.67 | Pharmacologic treatment of parkinsonian tremor. ( Koller, WC, 1986) |
| "An electromyographic method was used to study the effect of combination therapy with L-dopa and trihexyphenidyl on tremor in thirty patients suffering from extrapyramidal motor system disease." | 3.66 | Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor. ( Hökendorf, H, 1979) |
| "3." | 2.64 | Nomifensine in Parkinson's disease. ( Bedard, P; Marsden, CD; Parkes, JD, 1977) |
| " Hence we would advise that if for any reason anticholinergic drugs are to be withdrawn in patients receiving a stable dosage of levodopa this must be done slowly." | 2.64 | Levodopa in Parkinsonism: the effects of withdrawal of anticholinergic drugs. ( Hughes, RC; Polgar, JG; Walton, JN; Weightman, D, 1971) |
| "Current long-term treatment of Parkinson's disease is inadequate, and improved symptomatic and neuroprotective therapies are needed." | 2.38 | N-methyl-D-aspartate antagonists in the treatment of Parkinson's disease. ( Greenamyre, JT; O'Brien, CF, 1991) |
| "The treatment of Parkinson's disease today is complex, time-consuming, but rewarding." | 2.35 | Advances in the management of parkinson's disease. ( Marsden, CD, 1976) |
| "However, pneumonia combined with malignant hyperthermia and SIADH has rarely been reported." | 1.56 | Trihexyphenidyl induced malignant hyperthermia in a patient with Parkinson's disease complicated with pneumonia: A case report. ( Chen, Y; Feng, C; Kang, Y; Liu, F; Ma, W; Xu, G; Zhao, J, 2020) |
| "Paroxysmal exercise-induced dystonia (PED) is a rare, typically idiopathic familial condition, although sporadic and secondary cases have been reported." | 1.32 | Paroxysmal exercise-induced dystonia as a presenting feature of young-onset Parkinson's disease. ( Bhatia, KP; Bozi, M, 2003) |
| "Trihexyphenidyl (THP) is a drug commonly used to reduce parkinsonian symptoms." | 1.32 | Treatment with subthreshold doses of caffeine plus trihexyphenidyl fully restores locomotion and exploratory activity in reserpinized rats. ( Alvarez-Cervera, F; Arankowsky-Sandoval, G; Góngora-Alfaro, JL; Moo-Puc, RE; Villanueva-Toledo, J, 2004) |
| "We report a patient with Parkinson's disease who developed orobuccal dyskinesia while being treated with trihexyphenidyl (Artane)." | 1.29 | Orobuccal dyskinesia associated with trihexyphenidyl therapy in a patient with Parkinson's disease. ( Hauser, RA; Olanow, CW, 1993) |
| "We investigated a patient with Parkinson's disease accompanied by intellectual impairment induced by long-term AC therapy." | 1.29 | Positron emission tomography of reversible intellectual impairment induced by long-term anticholinergic therapy. ( Momose, T; Nishiyama, K; Sakuta, M; Sugishita, M, 1995) |
| "Groups of patients with Parkinson's disease, either medicated, or unmedicated and early in the course, together with age- and IQ-matched control subjects were tested in two paradigms measuring different aspects of selective attention." | 1.28 | Impaired extra-dimensional shift performance in medicated and unmedicated Parkinson's disease: evidence for a specific attentional dysfunction. ( Downes, JJ; Evenden, JL; Morris, RG; Robbins, TW; Roberts, AC; Sahakian, BJ, 1989) |
| "Two patients with Parkinson's disease are reported, in whom painful sensory phenomena preceded or accompanied the disease process." | 1.27 | Anticholinergic-induced analgesia: possible role for the cholinergic system in abnormal sensory symptoms in Parkinson's disease. ( Sandyk, R, 1986) |
| "It is important that Parkinson's disease be considered in the differential diagnosis of a progressively evolving hemiparesis." | 1.26 | A pseudohemipharetic form of Parkinson's disease. ( Gilbert, GJ, 1976) |
| "A patient with confirmed western equine encephalitis had the rapid onset of postencephalitic parkinsonian sequelae." | 1.26 | Western equine encephalitis with rapid onset of parkinsonism. ( Barthal, JS; Garrett, G; Schultz, DR, 1977) |
| " Although directly related to daily dosage of levodopa, the myoclonus was specifically blocked by the serotonin antagonist, methysergide." | 1.25 | Levodopa-induced myoclonus. ( Bergen, D; Goetz, C; Klawans, HL, 1975) |
| "The most disabling form of Parkinsonism is that occurring after encephalitis." | 1.23 | Therapy of Parkinson's disease. ( VAN METER, JR, 1950) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 133 (77.33) | 18.7374 |
| 1990's | 23 (13.37) | 18.2507 |
| 2000's | 9 (5.23) | 29.6817 |
| 2010's | 4 (2.33) | 24.3611 |
| 2020's | 3 (1.74) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, HY | 3 |
| Hao, X | 3 |
| Lu, R | 3 |
| Li, T | 3 |
| Pu, L | 3 |
| Liu, W | 3 |
| Liang, Z | 3 |
| Zhao, J | 1 |
| Xu, G | 1 |
| Feng, C | 1 |
| Chen, Y | 1 |
| Kang, Y | 1 |
| Liu, F | 1 |
| Ma, W | 1 |
| Sahoo, LK | 1 |
| Holla, VV | 1 |
| Batra, D | 1 |
| Prasad, S | 1 |
| Bhattacharya, A | 1 |
| Kamble, N | 1 |
| Yadav, R | 1 |
| Pal, PK | 2 |
| Lefaucheur, R | 1 |
| Le Goff, F | 1 |
| Gaillon, G | 1 |
| Triquenot-Bagan, A | 1 |
| Maltête, D | 1 |
| Prashantha, DK | 1 |
| Zhe, X | 1 |
| Qu, QM | 1 |
| Wang, RL | 1 |
| Cao, HM | 1 |
| Qiao, J | 1 |
| Guo, F | 1 |
| Herzallah, MM | 1 |
| Moustafa, AA | 1 |
| Misk, AJ | 1 |
| Al-Dweib, LH | 1 |
| Abdelrazeq, SA | 1 |
| Myers, CE | 1 |
| Gluck, MA | 1 |
| Hashim, HZ | 1 |
| Wan Musa, WR | 1 |
| Ngiu, CS | 1 |
| Wan Yahya, WN | 1 |
| Tan, HJ | 1 |
| Ibrahim, N | 1 |
| Baba, Y | 1 |
| Higuchi, MA | 1 |
| Abe, H | 1 |
| Fukuyama, K | 1 |
| Onozawa, R | 1 |
| Uehara, Y | 1 |
| Inoue, T | 1 |
| Yamada, T | 1 |
| SCHULSINGER, F | 1 |
| SEGARD, M | 1 |
| SIGURET, G | 1 |
| HOLT, CL | 1 |
| DOSHAY, LJ | 4 |
| CONSTABLE, K | 3 |
| ZIER, A | 3 |
| KAPLAN, HA | 1 |
| MACHOVER, S | 1 |
| RABINER, A | 1 |
| SCHMIDT, P | 1 |
| DE MAAR, EW | 1 |
| VON KEYSERLINGK, H | 1 |
| PORTEOUS, HB | 1 |
| ROSS, DN | 1 |
| HARDER, A | 1 |
| PRELICZ, T | 1 |
| BERGER, H | 2 |
| KIRCHHOF, JK | 2 |
| RASHKIS, HA | 1 |
| SMARR, ER | 1 |
| KAFER, JP | 1 |
| POCH, GF | 1 |
| NAHUNEK, K | 1 |
| RYBAKOVA, V | 1 |
| KONCHEGUL, L | 1 |
| EDWARDS, CE | 1 |
| O'DOHERTY, DS | 2 |
| COOPER, IS | 1 |
| Tanaka, M | 1 |
| Okamoto, K | 1 |
| AKIMOTO, H | 1 |
| SHIKIBA, S | 1 |
| NAGAO, T | 1 |
| NARABAYASHI, H | 1 |
| SCHWAB, RS | 2 |
| PAKKENBERG, H | 2 |
| POLEZHAEVA, AI | 1 |
| HAFFNER, Z | 1 |
| POPPEL, A | 1 |
| WALKER, LG | 1 |
| HIEBERT, T | 1 |
| SMYTH, NP | 1 |
| GILLINGHAM, FJ | 1 |
| KALYANARAMAN, S | 1 |
| BURNS, BD | 1 |
| DEJONG, D | 1 |
| SOLIS-QUIROGA, OH | 1 |
| MEYER, JS | 1 |
| MAGEE, KR | 1 |
| STRANG, RR | 2 |
| LERNER, PF | 1 |
| MANDEL, W | 2 |
| CLAFFEY, B | 1 |
| MARGOLIS, LH | 1 |
| OLIVER, WA | 1 |
| Bozi, M | 1 |
| Bhatia, KP | 1 |
| VAN METER, JR | 1 |
| EFFRON, AS | 1 |
| FARQUHAR, JW | 1 |
| ALONSO FERNANDEZ, F | 1 |
| BERKOWITZ, B | 1 |
| ALVERMANN, E | 1 |
| PIAZZESI, W | 1 |
| WRIGHT, WB | 1 |
| Moo-Puc, RE | 1 |
| Villanueva-Toledo, J | 1 |
| Arankowsky-Sandoval, G | 1 |
| Alvarez-Cervera, F | 1 |
| Góngora-Alfaro, JL | 1 |
| REMOUCHAMPS, L | 1 |
| VERBEKE, R | 1 |
| Funakawa, I | 1 |
| Jinnai, K | 1 |
| TILLMANN, WR | 1 |
| Preskorn, SH | 2 |
| Winer, JA | 1 |
| Bahn, S | 1 |
| Mancall, EL | 1 |
| Covington, TR | 1 |
| Alonso, RJ | 1 |
| Koller, WC | 3 |
| Kehr, W | 1 |
| Pavoncello, S | 1 |
| Di Bianco, V | 1 |
| Di Castro, A | 1 |
| Caviglia, A | 1 |
| Cellitti, M | 1 |
| Mitsui, T | 1 |
| Kawai, H | 1 |
| Sakoda, S | 1 |
| Miyata, M | 1 |
| Saito, S | 1 |
| Krack, P | 1 |
| Marion, MH | 1 |
| Linazasoro, G | 1 |
| Hineno, T | 1 |
| Mizobuchi, M | 1 |
| Nishimatsu, O | 1 |
| Horiguchi, J | 1 |
| Kakimoto, Y | 1 |
| Hauser, RA | 1 |
| Olanow, CW | 1 |
| Noda, K | 1 |
| Isozaki, E | 1 |
| Miyamoto, K | 1 |
| Hirose, K | 1 |
| Tanabe, H | 1 |
| Oda, M | 1 |
| Kao, KP | 1 |
| Kwan, SY | 1 |
| Lin, KP | 1 |
| Chang, YC | 1 |
| Nishiyama, K | 2 |
| Mizuno, T | 1 |
| Sakuta, M | 2 |
| Kurisaki, H | 1 |
| Van Spaendonck, KP | 1 |
| Berger, HJ | 1 |
| Horstink, MW | 1 |
| Buytenhuijs, EL | 1 |
| Cools, AR | 1 |
| Momose, T | 1 |
| Sugishita, M | 1 |
| Gorchein, A | 1 |
| Shinotoh, H | 1 |
| Asahina, M | 1 |
| Inoue, O | 1 |
| Suhara, T | 1 |
| Hirayama, K | 2 |
| Tateno, Y | 1 |
| Kishore, A | 1 |
| Snow, BJ | 1 |
| Kirollos, C | 1 |
| Charlett, A | 1 |
| O'Neill, CJ | 1 |
| Kosik, R | 1 |
| Mozol, K | 1 |
| Purkiss, AG | 1 |
| Bowes, SG | 1 |
| Nicholson, PW | 1 |
| Hunt, WB | 1 |
| Weller, C | 1 |
| Dobbs, SM | 1 |
| Dobbs, RJ | 1 |
| van Laar, T | 1 |
| Lammers, GJ | 1 |
| Roos, RA | 1 |
| Gerritsen, JJ | 1 |
| Meinders, AE | 1 |
| Izurieta-Sánchez, P | 1 |
| Sarre, S | 1 |
| Ebinger, G | 1 |
| Michotte, Y | 1 |
| Bédard, MA | 1 |
| Pillon, B | 1 |
| Dubois, B | 1 |
| Duchesne, N | 1 |
| Masson, H | 1 |
| Agid, Y | 1 |
| Takahashi, S | 1 |
| Tohgi, H | 1 |
| Yonezawa, H | 1 |
| Obara, S | 1 |
| Yamazaki, E | 1 |
| Shad, MU | 1 |
| Marsh, C | 1 |
| Sakakibara, R | 1 |
| Uchiyama, T | 1 |
| Yoshiyama, M | 1 |
| Hattori, T | 1 |
| Greer, M | 1 |
| Gilbert, GJ | 1 |
| Ludin, HP | 2 |
| Ringwald, E | 2 |
| Lörincz, P | 2 |
| Barbeau, A | 1 |
| Campanella, G | 1 |
| Butterworth, RF | 1 |
| Yamada, K | 1 |
| Taylor, J | 1 |
| Bedard, P | 1 |
| Parkes, JD | 4 |
| Marsden, CD | 6 |
| Hökendorf, H | 1 |
| Mace, M | 1 |
| Rawlins, MD | 1 |
| Schultz, DR | 1 |
| Barthal, JS | 1 |
| Garrett, G | 1 |
| Mindham, RH | 1 |
| Kunz, F | 1 |
| Blonsky, ER | 2 |
| Butzer, JF | 1 |
| Silver, DE | 1 |
| Sahs, AL | 1 |
| Lukasiewicz, K | 1 |
| Allen, N | 1 |
| Knopp, W | 2 |
| Bianchine, JR | 1 |
| Evtushenko, SK | 1 |
| Klawans, HL | 2 |
| Goetz, C | 1 |
| Bergen, D | 1 |
| Algeri, S | 1 |
| Cerletti, C | 1 |
| Curcio, M | 1 |
| Morselli, PL | 2 |
| Bonollo, L | 1 |
| Buniva, G | 1 |
| Minazzi, M | 1 |
| Minoli, G | 1 |
| Stimmel, GL | 1 |
| Parkenberg, H | 1 |
| Jordan, N | 1 |
| Sagar, HJ | 1 |
| Cooper, JA | 1 |
| Schelosky, L | 1 |
| Benke, T | 1 |
| Poewe, WH | 1 |
| Greenamyre, JT | 1 |
| O'Brien, CF | 1 |
| Nakashima, K | 1 |
| Takahashi, K | 1 |
| Fahn, S | 2 |
| Burke, R | 1 |
| Stern, Y | 1 |
| Sandyk, R | 1 |
| Downes, JJ | 1 |
| Roberts, AC | 1 |
| Sahakian, BJ | 1 |
| Evenden, JL | 1 |
| Morris, RG | 1 |
| Robbins, TW | 1 |
| Ueno, S | 1 |
| Takahashi, M | 1 |
| Kajiyama, K | 1 |
| Okahisa, N | 1 |
| Hazama, T | 1 |
| Yorifuji, S | 1 |
| Tarui, S | 1 |
| Yamamoto, K | 1 |
| Noda, S | 1 |
| Umezaki, H | 1 |
| Giménez-Roldán, S | 1 |
| Mateo, D | 1 |
| Orbe, M | 1 |
| Muñoz-Blanco, JL | 1 |
| Hípola, D | 1 |
| Meerwaldt, JD | 1 |
| Hovestadt, A | 1 |
| Herbster, G | 1 |
| Sunohara, N | 1 |
| Mano, Y | 1 |
| Ando, K | 1 |
| Satoyoshi, E | 1 |
| Agnoli, A | 2 |
| Casacchia, M | 2 |
| Ruggieri, S | 2 |
| Volante, F | 2 |
| Accornero, N | 2 |
| Mano, T | 1 |
| Birket-Smith, E | 1 |
| Alstead, S | 1 |
| Oelszner, W | 1 |
| Walther, H | 1 |
| Wagner, U | 1 |
| Girard, P | 1 |
| Mansuy, L | 1 |
| Garde, A | 1 |
| Lapras, R | 1 |
| Naylor, RJ | 1 |
| Costall, B | 1 |
| Lavy, S | 1 |
| Marks, ES | 1 |
| Abramsky, O | 1 |
| Muenter, MD | 2 |
| Sharpless, NS | 2 |
| Tyce, GM | 2 |
| Dinapoli, RP | 1 |
| Benesová, O | 1 |
| Brown, DM | 1 |
| Hughes, BO | 1 |
| Meadows, JC | 1 |
| Spicer, B | 1 |
| Ericsson, AD | 1 |
| McKinney, AS | 1 |
| Rix, A | 2 |
| Wang, RI | 1 |
| Rimm, AA | 1 |
| Presthus, J | 1 |
| Martin, WE | 1 |
| Loewenson, RB | 1 |
| Resch, JA | 1 |
| Baker, AB | 1 |
| Dreyfuss, J | 1 |
| Beer, B | 1 |
| Devine, DD | 1 |
| Roberts, BF | 1 |
| Schreiber, EC | 1 |
| Freeman, H | 1 |
| Mehta, IS | 1 |
| Ciuca, I | 1 |
| Bulandra, R | 1 |
| Serbanesco, A | 1 |
| Ninosu, N | 1 |
| Wolf, SM | 1 |
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| Martinez, AJ | 1 |
| Utterback, RA | 1 |
| Papavasiliou, PS | 1 |
| Cotzias, GC | 1 |
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| Schwarz, GA | 1 |
| Siegfried, J | 1 |
| Horrocks, PM | 1 |
| Vicary, DJ | 1 |
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| Chase, TN | 1 |
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9 reviews available for trihexyphenidyl and Parkinson Disease
| Article | Year |
|---|---|
CURRENT VIEWS CONCERNING THE ETIOLOGY, PATHOPHYSIOLOGY, AND TREATMENT OF PARKINSON'S DISEASE.
Topics: Classification; Drug Therapy; Muscle Relaxants, Central; Neurosurgery; Neurosurgical Procedures; Par | 1964 |
Drug management of Parkinson's disease.
Topics: Amantadine; Antiparkinson Agents; Bromocriptine; Humans; Levodopa; Parkinson Disease; Selegiline; Tr | 1996 |
[Disturbance of micturition in Parkinson's disease].
Topics: Activities of Daily Living; Adult; Aged; Antiparkinson Agents; Female; Humans; Levodopa; Male; Middl | 2001 |
Advances in the management of parkinson's disease.
Topics: Amantadine; Anesthesia; Humans; Levodopa; Orphenadrine; Parasympatholytics; Parkinson Disease; Socia | 1976 |
N-methyl-D-aspartate antagonists in the treatment of Parkinson's disease.
Topics: Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; gamma-Aminobutyric Acid; Globus Pallidus; H | 1991 |
Antimuscarinic drugs in the treatment of movement disorders.
Topics: Adult; Attention; Dystonia; Humans; Memory; Movement Disorders; Parasympatholytics; Parkinson Diseas | 1990 |
The pharmacology of parkinsonism (a review).
Topics: Acetylcholine; Animals; Atropa belladonna; Atropine; Central Nervous System; Chlorpromazine; Dextroa | 1968 |
[Review of current pharmacotherapy of Parkinsonism. Comprehensive review].
Topics: 5-Hydroxytryptophan; Amantadine; Anticonvulsants; Apomorphine; Benztropine; Carboxy-Lyases; Chemical | 1973 |
[Factors which influence infavourably l-dopa treatment].
Topics: Administration, Oral; Dihydroxyphenylalanine; Drug Synergism; Drug Therapy, Combination; Humans; Par | 1973 |
23 trials available for trihexyphenidyl and Parkinson Disease
| Article | Year |
|---|---|
Objective measurement of activation of rigidity: diagnostic, pathogenetic and therapeutic implications in parkinsonism.
Topics: Adult; Aged; Antiparkinson Agents; Carbidopa; Delayed-Action Preparations; Drug Combinations; Female | 1996 |
Acute and long-term administration of anticholinergics in Parkinson's disease: specific effects on the subcortico-frontal syndrome.
Topics: Acute Disease; Cholinergic Antagonists; Cognition Disorders; Corpus Striatum; Cross-Over Studies; Do | 1999 |
Bromocriptine in Parkinson's disease.
Topics: Antiparkinson Agents; Bromocriptine; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Le | 1978 |
Nomifensine in Parkinson's disease.
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Isoquin | 1977 |
Psychiatric symptoms during l-dopa therapy for Parkinson's disease and their relationship to physical disability.
Topics: Aged; Amantadine; Carbidopa; Clinical Trials as Topic; Depression; Dose-Response Relationship, Drug; | 1976 |
[Clinical experience with bromocriptine, a central dopaminergic stimulator].
Topics: Aged; Amantadine; Bromocriptine; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dose-Respo | 1976 |
Elantrine in the treatment of parkinsonism.
Topics: Adult; Aged; Clinical Trials as Topic; Dibenzazepines; Drug Evaluation; Female; Humans; Male; Middle | 1976 |
Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up.
Topics: Activities of Daily Living; Aged; Amantadine; Benztropine; Clinical Trials as Topic; Diphenhydramine | 1975 |
Adjuvant therapy of parkinsonian tremor.
Topics: Aged; Antiparkinson Agents; Carbidopa; Clonazepam; Double-Blind Method; Drug Therapy, Combination; H | 1987 |
Drug therapy in parkinsonism.
Topics: Clinical Trials as Topic; Drug Tolerance; Humans; Parkinson Disease; Trihexyphenidyl | 1970 |
3-O-Methyldopa, L-dopa, and trihexyphenidyl in the treatment of Parkinson's disease.
Topics: Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Disability Evaluation; Drug Interactions; Fe | 1973 |
Some initial animal and human pharmacological studies with benapryzine (BRL 1288).
Topics: Acetylcholine; Aged; Animals; Antiparkinson Agents; Benzilates; Clinical Trials as Topic; Dose-Respo | 1973 |
Phase II multiclinic study of elantrine in parkinsonism.
Topics: Aged; Antiparkinson Agents; Clinical Trials as Topic; Dibenzazepines; Dimethylamines; Female; Humans | 1974 |
A controlled study comparing trihexyphenidyl hydrochloride plus levodopa with placebo plus levodopa in patients with Parkinson's disease.
Topics: Affective Symptoms; Aged; Anxiety; Clinical Trials as Topic; Confusion; Drug Evaluation; Drug Therap | 1974 |
A double-blind comparison of the efficacy of EX 10-029 and trihexyphenidyl hydrochloride in relieving drug-induced Parkinsonian symptoms.
Topics: Antiparkinson Agents; Clinical Trials as Topic; Female; Humans; Male; Methods; Middle Aged; Parkinso | 1972 |
[Comparative value of L-dopa, amantadine, anticholinergics, and their combinations in parkinsonian syndromes].
Topics: Amantadine; Antiparkinson Agents; Dihydroxyphenylalanine; Drug Combinations; Drug Synergism; Humans; | 1972 |
Anticholinergic withdrawal and benzhexol treatment in Parkinson's disease.
Topics: Adult; Aged; Dihydroxyphenylalanine; Disability Evaluation; Drug Synergism; Evaluation Studies as To | 1973 |
Parkinson disease treated with a suspected dopamine receptor agonist.
Topics: Adult; Aged; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Dihydroxyphenyla | 1974 |
[Treatment of parkinsonism with the Bulgarian preparations INHA-17 and bellazon].
Topics: Adult; Aged; Atropa belladonna; Clinical Trials as Topic; Humans; Isoniazid; Middle Aged; Parasympat | 1966 |
Psychiatric changes in patients treated with levodopa. I. The clinical experiment.
Topics: Activities of Daily Living; Adjustment Disorders; Aged; Amitriptyline; Clinical Trials as Topic; Dia | 1970 |
[Therapeutic effects of L-dopa and trihexyphenidyl in Parkinson's disease--an examination by a double blind method].
Topics: Administration, Oral; Adolescent; Adult; Aged; Analysis of Variance; Clinical Trials as Topic; Dihyd | 1971 |
Neutralization of extrapyramidal side-effects with Methixene.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Extrapyramidal Tracts; Female; Humans; Male; Middle Age | 1971 |
Levodopa in Parkinsonism: the effects of withdrawal of anticholinergic drugs.
Topics: Dihydroxyphenylalanine; Drug Synergism; Drug Tolerance; Female; Humans; Male; Methods; Neurologic Ma | 1971 |
140 other studies available for trihexyphenidyl and Parkinson Disease
| Article | Year |
|---|---|
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Effects of trihexyphenidyl on prefrontal executive function and spontaneous neural activity in patients with tremor-dominant Parkinson's disease: An fNIRS study.
Topics: Cognition; Executive Function; Humans; Parkinson Disease; Tremor; Trihexyphenidyl | 2022 |
Trihexyphenidyl induced malignant hyperthermia in a patient with Parkinson's disease complicated with pneumonia: A case report.
Topics: Antiparkinson Agents; Humans; Hyponatremia; Male; Malignant Hyperthermia; Middle Aged; Parkinson Dis | 2020 |
Comparison of effectiveness of trihexyphenidyl and levodopa on motor symptoms in Parkinson's disease.
Topics: Antiparkinson Agents; Humans; Hypokinesia; Infant, Newborn; Levodopa; Parkinson Disease; Treatment O | 2020 |
Severe dizziness following rivaroxaban introduction in a parkinsonian patient: Drug-drug interaction?
Topics: Anticoagulants; Antiparkinson Agents; Biotransformation; Dizziness; Drug Interactions; Drug Substitu | 2015 |
Serpentine tongue: A rare manifestation following initiation of levodopa therapy in a patient with Parkinson's disease.
Topics: Antiparkinson Agents; Dyskinesia, Drug-Induced; Humans; Levodopa; Male; Middle Aged; Parkinson Disea | 2009 |
[The use of antiparkinsonism drugs in 92 cases in Xi'an city].
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Amantadine; Antiparkinson Agents; China; Dopamine Agon | 2009 |
Depression impairs learning whereas anticholinergics impair transfer generalization in Parkinson patients tested on dopaminergic medications.
Topics: Aged; Cholinergic Antagonists; Depression; Dopamine Agonists; Female; Humans; Learning; Male; Middle | 2010 |
Parkinsonism complicating acute organophosphate insecticide poisoning.
Topics: Acute Disease; Adult; Antidotes; Antiparkinson Agents; Benserazide; Cholinesterase Inhibitors; Human | 2011 |
Anti-cholinergics for axial symptoms in Parkinson's disease after subthalamic stimulation.
Topics: Activities of Daily Living; Aged; Cholinergic Antagonists; Deep Brain Stimulation; Female; Humans; M | 2012 |
[Artane therapy of paralysis agitans].
Topics: Parkinson Disease; Trihexyphenidyl | 1952 |
[Therapeutic diagrams].
Topics: Antipsychotic Agents; Heterocyclic Compounds; Parkinson Disease; Phenothiazines; Trihexyphenidyl | 1953 |
Spider angiomas appearing during treatment with trihexyphenidyl.
Topics: Animals; Hemangioma; Humans; Parkinson Disease; Spiders; Trihexyphenidyl | 1953 |
Five year follow-up of treatment with trihexyphenidyl (artane); outcome in four hundred eleven cases of paralysis agitans.
Topics: Follow-Up Studies; Humans; Parkinson Disease; Trihexyphenidyl | 1954 |
Five year follow-up of artane treatment; the outcomes in 461 Parkinson cases.
Topics: Follow-Up Studies; Humans; Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl | 1953 |
A study of the effectiveness of drug therapy in parkinsonism.
Topics: Humans; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; Placebos; Scopolamine; | 1954 |
[Artane for treatment of Parkinson's syndrome].
Topics: Humans; Parkinson Disease; Trihexyphenidyl | 1955 |
[Pharmacokinetics in parkinsonism].
Topics: Anticonvulsants; Antipsychotic Agents; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Di | 1955 |
[P 119, a spasmolytic for the treatment of parkinsonism].
Topics: Parasympatholytics; Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl | 1955 |
Mental symptoms in parkinsonism following benzhexol hydrochloride therapy.
Topics: Humans; Mental Disorders; Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl | 1956 |
[An observation on the treatment of Parkinson's syndrome; results with the new drug ParKS 12].
Topics: Cardiovascular Agents; Muscle Relaxants, Central; Parkinson Disease; Piperidines; Trihexyphenidyl | 1956 |
Parkinsonism: treatment with curare.
Topics: Cardiovascular Agents; Curare; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; | 1956 |
Parkinsonism: treatment with curare.
Topics: Cardiovascular Agents; Curare; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; | 1956 |
Parkinsonism: treatment with curare.
Topics: Cardiovascular Agents; Curare; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; | 1956 |
Parkinsonism: treatment with curare.
Topics: Cardiovascular Agents; Curare; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; | 1956 |
[Study of combined therapy of parkinsonian conditions, especially postencephalitic conditions].
Topics: Autonomic Agents; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; Trihexypheni | 1956 |
[Study of combined therapy of parkinsonian conditions, especially postencephalitic conditions].
Topics: Autonomic Agents; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; Trihexypheni | 1956 |
[Study of combined therapy of parkinsonian conditions, especially postencephalitic conditions].
Topics: Autonomic Agents; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; Trihexypheni | 1956 |
[Study of combined therapy of parkinsonian conditions, especially postencephalitic conditions].
Topics: Autonomic Agents; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; Trihexypheni | 1956 |
Protection against reserpine-induced Parkinsonism.
Topics: Humans; Parkinson Disease; Parkinsonian Disorders; Reserpine; Trihexyphenidyl | 1957 |
Procyclidine hydrochloride (kemadrin) treatment of parkinsonism; result in 108 patients.
Topics: Parkinson Disease; Parkinsonian Disorders; Procyclidine; Trihexyphenidyl | 1957 |
[Cycrimine, a new drug in the treatment of Parkinson's disease & Parkinsonism].
Topics: Humans; Nervous System Diseases; Parkinson Disease; Piperidines; Trihexyphenidyl | 1957 |
[Parkinsonism-like symptoms caused by chlorpromazine therapy].
Topics: Chlorpromazine; Electroconvulsive Therapy; Humans; Parkinson Disease; Parkinsonian Disorders; Psycho | 1958 |
The use of kemadrin in the treatment of drug-induced parkinsonism; preliminary report.
Topics: Parkinson Disease; Parkinsonian Disorders; Procyclidine; Trihexyphenidyl | 1958 |
Anti-Parkinson drugs and their relationship to glaucoma.
Topics: Antiparkinson Agents; Cardiovascular Agents; Glaucoma; Muscle Relaxants, Central; Parkinson Disease; | 1958 |
Parkinsonism: drug therapy; neurosurgical therapy.
Topics: Cardiovascular Agents; Humans; Muscle Relaxants, Central; Parkinson Disease; Parkinsonian Disorders; | 1958 |
[Therapy for patients with early-stage Parkinson's disease].
Topics: Amantadine; Animals; Antiparkinson Agents; Bromocriptine; Dopamine Agonists; Drug Therapy, Combinati | 2003 |
[Clinical study of trihexyphenyl-HCl therapy of the parkinson syndrome].
Topics: Biomedical Research; Parkinson Disease; Trihexyphenidyl | 1961 |
Slow-release trihexyphenidyl in Parkinson's disease.
Topics: Humans; Parkinson Disease; Patient Discharge; Trihexyphenidyl | 1962 |
[Pathogenesis and medical treatment of parkinsonism].
Topics: Humans; Imipramine; Parkinson Disease; Parkinsonian Disorders; Piperidines; Trihexyphenidyl | 1963 |
[Preparations for the treatment of Parkinsonism-cyclodol and ridinol].
Topics: Parasympatholytics; Parkinson Disease; Parkinsonian Disorders; Piperidines; Trihexyphenidyl | 1962 |
[Clinical experiences on comparative studies of the preparations. Parkan and Artane].
Topics: Arteriosclerosis; Humans; Parkinson Disease; Trihexyphenidyl | 1963 |
Acute suppurative parotitis associated with certain drugs in the treatment of parkinsonism.
Topics: Humans; Parasympatholytics; Parkinson Disease; Parkinsonian Disorders; Parotitis; Trihexyphenidyl | 1962 |
PARKINSON'S DISEASE.
Topics: Amitriptyline; Dextroamphetamine; Humans; Imipramine; Muscle Relaxants, Central; Neurosurgery; Orphe | 1963 |
EFFECTS OF TRIHEXYPHENIDYL HYDROCHLORIDE (ARTANE) ON PARKINSON'S DISEASE.
Topics: Parkinson Disease; Parkinsonian Disorders; Placebos; Trihexyphenidyl | 1964 |
ORPHENADRINE IN THE TREATMENT OF PARKINSON'S DISEASE.
Topics: Biomedical Research; Geriatrics; Orphenadrine; Parkinson Disease; Parkinsonian Disorders; Pharmacolo | 1964 |
Use of biperiden hydrochloride in Parkinson's disease.
Topics: Biperiden; Humans; Parkinson Disease; Trihexyphenidyl | 1960 |
Recurrent thioperazine-induced extrapyramidal reaction following placebo substitution for maintenance antiparkinson drug.
Topics: Antiparkinson Agents; Antipsychotic Agents; Atropine Derivatives; Extrapyramidal Tracts; Parkinson D | 1961 |
Withdrawal of maintenance antiparkinson drug in the phenothiazine-induced extrapyramidal reaction.
Topics: Antiparkinson Agents; Conduct Disorder; Humans; Parkinson Disease; Phenothiazines; Trihexyphenidyl | 1961 |
Paroxysmal exercise-induced dystonia as a presenting feature of young-onset Parkinson's disease.
Topics: Adult; Age Factors; Antiparkinson Agents; Basal Ganglia; Diagnosis, Differential; Dopamine Plasma Me | 2003 |
Therapy of Parkinson's disease.
Topics: Diphenhydramine; Encephalitis; Humans; Mephenesin; Muscle Rigidity; Pain; Parkinson Disease; Parkins | 1950 |
Artane in the treatment of Parkinson's disease.
Topics: Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl | 1951 |
How to treat parkinsonism.
Topics: Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl | 1951 |
Treatment of parkinsonism in a child.
Topics: Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl | 1952 |
[First personal impressions on the treatment of the parkinsonian syndrome with artane].
Topics: Humans; Parkinson Disease; Parkinsonian Disorders; Social Behavior; Trihexyphenidyl | 1951 |
Trihexyphenidyl (artane), stramonium, and nonchemotherapy of paralysis agitans.
Topics: Alkaloids; Datura stramonium; Muscarinic Antagonists; Parkinson Disease; Trihexyphenidyl | 1952 |
[Combined belladonna-artane in small doses in the treatment of post-encephalitic parkinsonism].
Topics: Alkaloids; Atropa belladonna; Humans; Muscarinic Antagonists; Parasympatholytics; Parkinson Disease; | 1951 |
Behaviour disorders associated with Artane treatment of post-encephalitic Parkinsonism.
Topics: Conduct Disorder; Humans; Mental Disorders; Parkinson Disease; Parkinson Disease, Postencephalitic; | 1952 |
Treatment with subthreshold doses of caffeine plus trihexyphenidyl fully restores locomotion and exploratory activity in reserpinized rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Diseas | 2004 |
[Treatment of Parkinson's syndrome by trihexylphenidyl (artane)].
Topics: Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl | 1950 |
[Tactile hallucinations induced by trihexyphenidyl in a patient with Parkinson's disease].
Topics: Aged; Antiparkinson Agents; Female; Hallucinations; Humans; Parkinson Disease; Trihexyphenidyl | 2005 |
Artane in the treatment of Parkinson's disease; a report of its effectiveness alone and in combination with benadryl and parpanit.
Topics: Cyclopentanes; Diphenhydramine; Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl | 1949 |
Multiple medication use presenting as Parkinson's dementia complex: a message from Titanic.
Topics: Aged; Anti-Infective Agents; Antiparkinson Agents; Antipsychotic Agents; Bacteriuria; Ciprofloxacin; | 2008 |
Loss of teeth with antidepressant drug therapy.
Topics: Dental Caries; Diphenhydramine; Humans; Imipramine; Male; Middle Aged; Parkinson Disease; Psychophar | 1967 |
Therapy of neurologic disorders in the elderly.
Topics: Aged; Amantadine; Anticoagulants; Brain Ischemia; Bromocriptine; Carbidopa; Dexamethasone; Drug Inte | 1984 |
Disturbance of recent memory function in parkinsonian patients on anticholinergic therapy.
Topics: Aged; Humans; Memory; Mental Recall; Paired-Associate Learning; Parkinson Disease; Trihexyphenidyl; | 1984 |
[Drug therapy of Parkinson disease and parkinson disease-like symptoms].
Topics: Adenylyl Cyclases; Animals; Aromatic-L-Amino-Acid Decarboxylases; Biperiden; Brain; Catechol O-Methy | 1981 |
[Neurological aspects and modern trends in therapy of Parkinson's disease].
Topics: Atropine; Biperiden; Humans; Levodopa; Parasympatholytics; Parkinson Disease; Procyclidine; Trihexyp | 1980 |
Hereditary parkinsonism with multiple system degeneration: beneficial effect of anticholinergics, but not of levodopa.
Topics: Adult; Amantadine; Basal Ganglia; Carbidopa; Cerebellar Ataxia; Cholinergic Antagonists; Consanguini | 1994 |
"Apraxia of lid opening," a focal eyelid dystonia: clinical study of 32 patients.
Topics: Adult; Aged; Aged, 80 and over; Apraxias; Blepharospasm; Botulinum Toxins; Dose-Response Relationshi | 1994 |
Anticholinergics and dyskinesia.
Topics: Aged; Biperiden; Carbidopa; Drug Combinations; Drug Therapy, Combination; Dyskinesia, Drug-Induced; | 1994 |
Day-night variation of urine volume in Parkinson's disease.
Topics: Adult; Aged; Amantadine; Bromocriptine; Circadian Rhythm; Female; Humans; Levodopa; Male; Middle Age | 1994 |
Orobuccal dyskinesia associated with trihexyphenidyl therapy in a patient with Parkinson's disease.
Topics: Dyskinesia, Drug-Induced; Humans; Male; Middle Aged; Parasympatholytics; Parkinson Disease; Trihexyp | 1993 |
[Rhythmical involuntary movement at rest associated with olivo-ponto-cerebellar atrophy (OPCA)].
Topics: Adolescent; Aged; Brain; Clonazepam; Electromyography; Female; Humans; Levodopa; Male; Middle Aged; | 1993 |
Coexistence of Parkinson's disease and myasthenia gravis: a case report.
Topics: Brain; Cholinesterase Inhibitors; Female; Humans; Middle Aged; Myasthenia Gravis; Parkinson Disease; | 1993 |
Chronic dementia in Parkinson's disease treated by anticholinergic agents. Neuropsychological and neuroradiological examination.
Topics: Aged; Biperiden; Blood Glucose; Brain; Cerebral Cortex; Dementia; Energy Metabolism; Female; Humans; | 1993 |
Impaired cognitive shifting in parkinsonian patients on anticholinergic therapy.
Topics: Aged; Cognition; Female; Humans; Male; Middle Aged; Orphenadrine; Parasympatholytics; Parkinson Dise | 1993 |
Positron emission tomography of reversible intellectual impairment induced by long-term anticholinergic therapy.
Topics: Aged; Antiparkinson Agents; Cognition Disorders; Humans; Male; Parkinson Disease; Time Factors; Tomo | 1995 |
Treatment of Parkinson's disease in a patient with acute intermittent porphyria.
Topics: Aged; Antiparkinson Agents; Benserazide; Chlorpromazine; Dopamine Antagonists; Drug Interactions; Fe | 1995 |
Effects of trihexyphenidyl and L-dopa on brain muscarinic cholinergic receptor binding measured by positron emission tomography.
Topics: Aged; Binding, Competitive; Brain; Female; Humans; Kinetics; Levodopa; Male; Middle Aged; Parkinson | 1994 |
Antiparkinsonian drugs causing inappropriate antidiuretic hormone secretion.
Topics: Aged; Amantadine; Antiparkinson Agents; Carbidopa; Drug Therapy, Combination; Humans; Inappropriate | 1998 |
Effect of trihexyphenidyl, a non-selective antimuscarinic drug, on decarboxylation of L-dopa in hemi-Parkinson rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Biotransformation; Corpus Striatum; D | 1998 |
The effect of trihexyphenidyl, an anticholinergic agent, on regional cerebral blood flow and oxygen metabolism in patients with Parkinson's disease.
Topics: Cerebrovascular Circulation; Cholinergic Antagonists; Female; Humans; Male; Middle Aged; Oxygen Cons | 1999 |
The economic consequences of a drug-drug interaction.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Depression; Drug Interactions; Female; Fluoxetine; Halo | 2001 |
How to achieve maximum benefit for the patient with Parkinson's disease.
Topics: Aged; Amantadine; Carbidopa; Diagnosis, Differential; Histamine H1 Antagonists; Humans; Levodopa; Ne | 1976 |
A pseudohemipharetic form of Parkinson's disease.
Topics: Aged; Amantadine; Carbidopa; Diagnosis, Differential; Drug Therapy, Combination; Female; Functional | 1976 |
Uptake and efflux of 14-C-dopamine in platelets: evidence for a generalized defect in Parkinson's disease.
Topics: Adult; Aged; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Platelets; | 1975 |
Parkinson's disease.
Topics: Amantadine; Benztropine; Humans; Levodopa; Parkinson Disease; Procyclidine; Trihexyphenidyl | 1977 |
Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor.
Topics: Aged; Basal Ganglia Diseases; Drug Therapy, Combination; Electromyography; Female; Humans; Levodopa; | 1979 |
Parkinson's disease.
Topics: Aged; Drug Administration Schedule; Drug Therapy, Combination; Humans; Levodopa; Male; Parkinson Dis | 1979 |
Western equine encephalitis with rapid onset of parkinsonism.
Topics: Adult; Carbidopa; Encephalitis Virus, Western Equine; Encephalomyelitis, Equine; Female; Humans; Lev | 1977 |
[Combined treatment of parkinsonism with L-dopa and Parkopan].
Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disea | 1977 |
Hereditary Parkinsonism-dystonia with sustained control by L-DOPA and anticholinergic medication.
Topics: Adolescent; Adult; Aged; Dopamine beta-Hydroxylase; Dystonia Musculorum Deformans; Female; Growth Ho | 1976 |
Drug therapy of parkinsonism.
Topics: Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior; Dopa Decarboxylase; Drug Interac | 1976 |
[Combined treatment of Parkinsonism with levopa, midantan and anticholinergic drugs].
Topics: Acetylcholine; Adult; Aged; Amantadine; Antiparkinson Agents; Cholinesterases; Drug Therapy, Combina | 1976 |
Levodopa-induced myoclonus.
Topics: 5-Hydroxytryptophan; Aged; Amantadine; Amphetamine; Animals; Benztropine; Dopamine Antagonists; Dose | 1975 |
Effect of anticholinergic drugs on gastro-intestinal absorption of L-dopa in rats and in man.
Topics: Administration, Oral; Adult; Aged; Animals; Atropine; Digestive System; Drug Interactions; Female; H | 1976 |
Neuroleptics and the corpus striatum: clinical implications.
Topics: Acetylcholine; Basal Ganglia Diseases; Benztropine; Corpus Striatum; Dopamine; Fluphenazine; Haloper | 1976 |
[Treatment of parkinsonism].
Topics: Amantadine; Benztropine; Biperiden; Humans; Levodopa; Orphenadrine; Parkinson Disease; Procyclidine; | 1976 |
A component analysis of the generation and release of isometric force in Parkinson's disease.
Topics: Bromocriptine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combina | 1992 |
Effects of treatment with trihexyphenidyl on cognitive function in early Parkinson's disease.
Topics: Adult; Aged; Cognition Disorders; Female; Humans; Intelligence Tests; Male; Memory Disorders; Middle | 1991 |
Exteroceptive suppression of the masseter and temporalis muscles and parkinsonian rigidity.
Topics: Adult; Aged; Amantadine; Basal Ganglia; Bromocriptine; Electric Stimulation; Electromyography; Femal | 1991 |
Anticholinergic-induced analgesia: possible role for the cholinergic system in abnormal sensory symptoms in Parkinson's disease.
Topics: Analgesia; Female; Humans; Male; Middle Aged; Pain; Palliative Care; Parasympathetic Nervous System; | 1986 |
Impaired extra-dimensional shift performance in medicated and unmedicated Parkinson's disease: evidence for a specific attentional dysfunction.
Topics: Aged; Attention; Drug Therapy, Combination; Female; Form Perception; Humans; Levodopa; Male; Middle | 1989 |
Parkinson's disease and myasthenia gravis: adverse effect of trihexyphenidyl on neuromuscular transmission.
Topics: Humans; Male; Middle Aged; Myasthenia Gravis; Neuromuscular Junction; Parkinson Disease; Synaptic Tr | 1987 |
[Parkinson's disease associated with trihexyphenidyl (THP) induced dysphonia plicae ventricularis].
Topics: Aged; Female; Humans; Movement Disorders; Parkinson Disease; Sulpiride; Tongue Diseases; Trihexyphen | 1988 |
Acute pharmacologic tests in cranial dystonia.
Topics: Adult; Aged; Basal Ganglia Diseases; Clonazepam; Diagnosis, Differential; Double-Blind Method; Femal | 1988 |
Adverse effect of benzhexol on memory in Parkinson's disease.
Topics: Humans; Memory; Parkinson Disease; Trihexyphenidyl | 1988 |
Pharmacologic treatment of parkinsonian tremor.
Topics: Amantadine; Carbidopa; Drug Combinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Tr | 1986 |
Idiopathic dystonia-parkinsonism with marked diurnal fluctuation of symptoms.
Topics: Adult; Bromocriptine; Electromyography; Electrophysiology; Female; Humans; Levodopa; Male; Middle Ag | 1985 |
Parkinson's tremor, relief by an antiaminic drug (BC 105). Discussion on the biochemical pathogenesis of Parkinsonian tremor.
Topics: Adult; Aged; Benzocycloheptenes; Dihydroxyphenylalanine; Ergolines; Female; Histamine H1 Antagonists | 1972 |
[Dyskinesia induced by anticholinergic drugs--electrophysiological analysis].
Topics: Aged; Benztropine; Biperiden; Electromyography; Female; Humans; Male; Middle Aged; Movement Disorder | 1974 |
Abnormal involuntary movements induced by anticholinergic therapy.
Topics: Aged; Biperiden; Dibenzazepines; Female; Humans; Mastication; Middle Aged; Movement Disorders; Orphe | 1974 |
[Experimental testing of some piperidine propanol diastereomers in animals as potential parkinsonism drugs].
Topics: 1-Propanol; Animals; Central Nervous System; Ileum; Mice; Organ Culture Techniques; Parasympatholyti | 1971 |
[Treatment of Parkinson's disease].
Topics: Antidepressive Agents; Histamine H1 Antagonists; Humans; Muscles; Parkinson Disease; Trihexyphenidyl | 1966 |
The relationship between the inhibition of dopamine uptake and the enhancement of amphetamine stereotypy.
Topics: Amantadine; Amphetamine; Animals; Behavior, Animal; Chlorpheniramine; Dopamine; Dopamine Antagonists | 1971 |
Parkinsonism and hyperthyroidism.
Topics: Diazepam; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Male; | 1974 |
3-O-Methyldopa in Parkinson's disease.
Topics: Antiparkinson Agents; Drug Antagonism; Drug Therapy, Combination; Humans; Levodopa; Methyldopa; Park | 1974 |
Fluphenazine-induced parkinsonism in the baboon: pharmacological and metabolic studies.
Topics: Animals; Basal Ganglia Diseases; Benztropine; Carbon Isotopes; Chromatography, Thin Layer; Feces; Fe | 1972 |
Permanent dementia in idiopathic Parkinsonism treated with levodopa.
Topics: Aged; Amantadine; Brain; Dihydroxyphenylalanine; Electroencephalography; Humans; Male; Parkinson Dis | 1973 |
Unilateral Parkinson's disease, clinical and neuropathologic findings. A case report.
Topics: Autopsy; Brain; Cerebral Ventricles; Dihydroxyphenylalanine; Humans; Male; Middle Aged; Neurons; Par | 1973 |
Levodopa and dopamine in cerebrospinal fluid.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Carbidopa; Dihydroxyphenylalanine; | 1973 |
Sporadic and familial parkinsonism and motor neuron disease.
Topics: Aged; Amantadine; Amyotrophic Lateral Sclerosis; Cerebellar Diseases; Corpus Striatum; Dihydroxyphen | 1973 |
[Present-day treatment of parkinsonism in the aged].
Topics: Aged; Amantadine; Antiparkinson Agents; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Therapy, Combin | 1973 |
Comparison of the renin response to dopamine and noradrenaline in normal subjects and patients with autonomic insufficiency.
Topics: Adult; Aged; Autonomic Nervous System; Blood Pressure; Diet; Dopamine; Fecal Incontinence; Humans; H | 1974 |
Comparative trial of benzhexol, amantadine, and levodopa in the treatment of Parkinson's disease.
Topics: Aged; Amantadine; Cognition Disorders; Dihydroxyphenylalanine; Drug Therapy, Combination; Edema; Eye | 1974 |
Benzhexol-induced blindness in Parkinson's disease.
Topics: Aged; Blindness; Female; Glaucoma; Humans; Male; Middle Aged; Parkinson Disease; Time Factors; Trihe | 1972 |
Relationship between desipramine plasma levels and the effect in Parkinson's syndrome.
Topics: Adult; Aged; Contracture; Desipramine; Drug Synergism; Female; Humans; Male; Middle Aged; Paralysis; | 1972 |
Comparison of trihexyphenidyl and dihydromorphanthridine derivative in control of tremor of parkinsonism.
Topics: Adult; Aged; Antiparkinson Agents; Dibenzazepines; Dimethylamines; Female; Humans; Male; Middle Aged | 1972 |
A comparative study of the effects of anti-parkinson drugs on the oxotremorine-induced EEG and muscular activities.
Topics: Animals; Diphenhydramine; Drug Antagonism; Electroencephalography; Male; Muscle Tonus; Muscles; Orph | 1971 |
Lack of indication for use of antiparkinson medication. A follow-up study.
Topics: Adolescent; Adult; Female; Follow-Up Studies; Humans; Intellectual Disability; Male; Mental Disorder | 1971 |
[Attempt at treating parkinsonism with L-dopa and Artane].
Topics: Aged; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Humans; Male; Middle Aged | 1971 |
[Action of amantadine on parkinsonian tremor].
Topics: Adult; Aged; Amantadine; Ergolines; Female; Humans; Male; Middle Aged; Parkinson Disease; Promethazi | 1971 |
Withdrawal of antiparkinson drugs.
Topics: Biperiden; Butyrophenones; Female; Humans; Male; Parasympatholytics; Parkinson Disease; Psychotic Di | 1971 |
Parkinsonism and dopa.
Topics: Dihydroxyphenylalanine; Humans; New Zealand; Orphenadrine; Parkinson Disease; Parkinson Disease, Pos | 1969 |
[Effect of a combined L-Dopa and decarboxylase inhibitor (Ro 4-4602) therapy in parkinsonism patients. Quantitative analysis of bradykinesia using reaction times].
Topics: Aged; Carboxy-Lyases; Desipramine; Dihydroxyphenylalanine; Discrimination, Psychological; Drug Syner | 1969 |
Reversal by levodopa of cholinergic hypersensitivity in Parkinson's disease.
Topics: Brain; Dihydroxyphenylalanine; Dopamine; Drug Hypersensitivity; Female; Handwriting; Humans; Injecti | 1971 |
Transitory procaine-induced Parkinsonism.
Topics: Chronic Disease; Dihydroxyphenylalanine; Female; Humans; Middle Aged; Parkinson Disease; Parkinson D | 1971 |
[Treatment of parkinsonism with benzhexole (Artane and Artane-sequel)].
Topics: Humans; Parkinson Disease; Trihexyphenidyl | 1967 |
Parkinson's disease presenting as hypothyroidism.
Topics: Diagnosis, Differential; Female; Functional Laterality; Humans; Hypothyroidism; Male; Middle Aged; M | 1968 |
The parkinsonian tremor in sleep.
Topics: Aged; Electroencephalography; Eye Movements; Female; Humans; Male; Middle Aged; Movement; Parkinson | 1968 |
The antiparkinsonian activity of monoamine oxidase inhibitors and other agents in rats and mice.
Topics: Animals; Dextroamphetamine; Diphenhydramine; Imipramine; Iproniazid; Isocarboxazid; Mice; Monoamine | 1968 |
Reversal of central anticholinergic syndrome in man by physostigmine.
Topics: Aged; Ataxia; Central Nervous System Diseases; Child; Cognition Disorders; Delirium; Female; Halluci | 1968 |
Antiparkinsonism drugs.
Topics: Antidepressive Agents; Atropine; Diphenhydramine; Humans; Orphenadrine; Parasympatholytics; Parkinso | 1965 |
Antiparkinsonism medication for the phenothiazine-induced pyramidal-extrapyramidal syndrome in elderly brain-damaged patients.
Topics: Aged; Brain Damage, Chronic; Chlorpromazine; Female; Humans; Male; Parkinson Disease; Perphenazine; | 1965 |
[Prolonged use of ponalid in extapyramidal drug-induced syndromes].
Topics: Humans; Movement Disorders; Parkinson Disease; Parkinson Disease, Secondary; Salivary Gland Diseases | 1966 |
Treatment of parkinsonism with artane and slow release artane.
Topics: Delayed-Action Preparations; Humans; Parkinson Disease; Trihexyphenidyl | 1966 |