trihexyphenidyl has been researched along with Nerve Degeneration in 4 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshiyama, Y | 1 |
| Kojima, A | 1 |
| Itoh, K | 1 |
| Uchiyama, T | 1 |
| Arai, K | 1 |
| Bédard, MA | 1 |
| Pillon, B | 1 |
| Dubois, B | 1 |
| Duchesne, N | 1 |
| Masson, H | 1 |
| Agid, Y | 1 |
| Brait, K | 1 |
| Fahn, S | 1 |
| Schwarz, GA | 1 |
| Powell, HC | 1 |
| London, GW | 1 |
| Lampert, PW | 1 |
1 trial available for trihexyphenidyl and Nerve Degeneration
| Article | Year |
|---|---|
Acute and long-term administration of anticholinergics in Parkinson's disease: specific effects on the subcortico-frontal syndrome.
Topics: Acute Disease; Cholinergic Antagonists; Cognition Disorders; Corpus Striatum; Cross-Over Studies; Do | 1999 |
3 other studies available for trihexyphenidyl and Nerve Degeneration
| Article | Year |
|---|---|
Anticholinergics boost the pathological process of neurodegeneration with increased inflammation in a tauopathy mouse model.
Topics: Animals; Benzilates; Cholinergic Antagonists; Disease Models, Animal; Hippocampus; Inflammation; Mic | 2012 |
Sporadic and familial parkinsonism and motor neuron disease.
Topics: Aged; Amantadine; Amyotrophic Lateral Sclerosis; Cerebellar Diseases; Corpus Striatum; Dihydroxyphen | 1973 |
Neurofibrillary tangles in progressive supranuclear palsy. Electron microscopic observations.
Topics: Aged; Amantadine; Brain; Brain Diseases; Bulbar Palsy, Progressive; Dementia; Dihydroxyphenylalanine | 1974 |