trihexyphenidyl has been researched along with Myasthenia Gravis in 2 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 55-year-old man with idiopathic Parkinson's disease developed myasthenia gravis shortly after taking trihexyphenidyl." | 7.67 | Parkinson's disease and myasthenia gravis: adverse effect of trihexyphenidyl on neuromuscular transmission. ( Hazama, T; Kajiyama, K; Okahisa, N; Takahashi, M; Tarui, S; Ueno, S; Yorifuji, S, 1987) |
| "A 55-year-old man with idiopathic Parkinson's disease developed myasthenia gravis shortly after taking trihexyphenidyl." | 3.67 | Parkinson's disease and myasthenia gravis: adverse effect of trihexyphenidyl on neuromuscular transmission. ( Hazama, T; Kajiyama, K; Okahisa, N; Takahashi, M; Tarui, S; Ueno, S; Yorifuji, S, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kao, KP | 1 |
| Kwan, SY | 1 |
| Lin, KP | 1 |
| Chang, YC | 1 |
| Ueno, S | 1 |
| Takahashi, M | 1 |
| Kajiyama, K | 1 |
| Okahisa, N | 1 |
| Hazama, T | 1 |
| Yorifuji, S | 1 |
| Tarui, S | 1 |
2 other studies available for trihexyphenidyl and Myasthenia Gravis
| Article | Year |
|---|---|
Coexistence of Parkinson's disease and myasthenia gravis: a case report.
Topics: Brain; Cholinesterase Inhibitors; Female; Humans; Middle Aged; Myasthenia Gravis; Parkinson Disease; | 1993 |
Parkinson's disease and myasthenia gravis: adverse effect of trihexyphenidyl on neuromuscular transmission.
Topics: Humans; Male; Middle Aged; Myasthenia Gravis; Neuromuscular Junction; Parkinson Disease; Synaptic Tr | 1987 |