trihexyphenidyl has been researched along with Muscle Rigidity in 12 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The most disabling form of Parkinsonism is that occurring after encephalitis." | 1.23 | Therapy of Parkinson's disease. ( VAN METER, JR, 1950) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| VAN METER, JR | 1 |
| Fann, WE | 1 |
| Lake, CR | 1 |
| Kirollos, C | 1 |
| Charlett, A | 1 |
| O'Neill, CJ | 1 |
| Kosik, R | 1 |
| Mozol, K | 1 |
| Purkiss, AG | 1 |
| Bowes, SG | 1 |
| Nicholson, PW | 1 |
| Hunt, WB | 1 |
| Weller, C | 1 |
| Dobbs, SM | 1 |
| Dobbs, RJ | 1 |
| Drobný, M | 1 |
| Adamkov, J | 1 |
| Svaleková, A | 1 |
| Fundárek, J | 1 |
| Agnoli, A | 1 |
| Ruggieri, S | 1 |
| Denaro, A | 1 |
| Lelli, A | 1 |
| Geller, B | 1 |
| Greydanus, DE | 1 |
| Butzer, JF | 1 |
| Silver, DE | 1 |
| Sahs, AL | 1 |
| Goldstein, JM | 1 |
| Barnett, A | 1 |
| Malick, JB | 1 |
| Nakashima, K | 1 |
| Takahashi, K | 1 |
| Blonsky, ER | 1 |
| Ericsson, AD | 1 |
| McKinney, AS | 1 |
| Rix, A | 1 |
| Wang, RI | 1 |
| Rimm, AA | 1 |
| Ahtee, L | 1 |
| Kääriäinen, I | 1 |
| Paasonen, MK | 1 |
| Chase, TN | 1 |
| Woods, AC | 1 |
| Glaubiger, GA | 1 |
5 trials available for trihexyphenidyl and Muscle Rigidity
| Article | Year |
|---|---|
On the coexistence of parkinsonism and tardive dyskinesia.
Topics: Amantadine; Antiparkinson Agents; Cross-Over Studies; Double-Blind Method; Dyskinesia, Drug-Induced; | 1974 |
Objective measurement of activation of rigidity: diagnostic, pathogenetic and therapeutic implications in parkinsonism.
Topics: Adult; Aged; Antiparkinson Agents; Carbidopa; Delayed-Action Preparations; Drug Combinations; Female | 1996 |
Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up.
Topics: Activities of Daily Living; Aged; Amantadine; Benztropine; Clinical Trials as Topic; Diphenhydramine | 1975 |
Phase II multiclinic study of elantrine in parkinsonism.
Topics: Aged; Antiparkinson Agents; Clinical Trials as Topic; Dibenzazepines; Dimethylamines; Female; Humans | 1974 |
Parkinson disease treated with a suspected dopamine receptor agonist.
Topics: Adult; Aged; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Dihydroxyphenyla | 1974 |
7 other studies available for trihexyphenidyl and Muscle Rigidity
| Article | Year |
|---|---|
Therapy of Parkinson's disease.
Topics: Diphenhydramine; Encephalitis; Humans; Mephenesin; Muscle Rigidity; Pain; Parkinson Disease; Parkins | 1950 |
[Therapy of rigidity and hypokinesis in old age using Sinemet].
Topics: Aged; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Movement Disorders; | 1979 |
Parkinson's disease improvement after the addition of levodopa-carbidopa to anticholinergic treatment. An open controlled study.
Topics: Administration, Oral; Adult; Aged; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Female; Hu | 1978 |
Haloperidol-induced comatose state with hyperthermia and rigidity in adolescence: two case reports with a literature review.
Topics: Adolescent; Child; Child Behavior Disorders; Coma; Female; Fever; Haloperidol; Humans; Male; Muscle | 1979 |
The evaluation of anti-parkinson drugs on reserpine-induced rigidity in rats.
Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Benztropine; Carbidopa; Hindlimb; Levodopa; | 1975 |
Exteroceptive suppression of the masseter and temporalis muscles and parkinsonian rigidity.
Topics: Adult; Aged; Amantadine; Basal Ganglia; Bromocriptine; Electric Stimulation; Electromyography; Femal | 1991 |
Effect of nalorphine and antiparkinsonian drugs on methadone-induced rigidity; relation to homovanillic acid content of nucleus caudatus.
Topics: Amantadine; Animals; Atropine; Body Temperature; Brain; Caudate Nucleus; Depression, Chemical; Dose- | 1972 |