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trihexyphenidyl and Movement Disorders

trihexyphenidyl has been researched along with Movement Disorders in 45 studies

Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"There are conflicting reports regarding the efficacy of trihexyphenidyl, an anticholinergic drug, for treatment of dystonia in cerebral palsy."7.77Trihexyphenidyl improves motor function in children with dystonic cerebral palsy: a retrospective analysis. ( Ben-Pazi, H, 2011)
"The clinical efficacy of the trihexyphenidyl was investigated in 100 patients with movement disorders."7.67Treatment of movement disorders with trihexyphenidyl. ( Gunderson, CH; Jabbari, B; Miller, J; Rosenberg, ML; Scherokman, B, 1989)
"There are conflicting reports regarding the efficacy of trihexyphenidyl, an anticholinergic drug, for treatment of dystonia in cerebral palsy."3.77Trihexyphenidyl improves motor function in children with dystonic cerebral palsy: a retrospective analysis. ( Ben-Pazi, H, 2011)
"The clinical efficacy of the trihexyphenidyl was investigated in 100 patients with movement disorders."3.67Treatment of movement disorders with trihexyphenidyl. ( Gunderson, CH; Jabbari, B; Miller, J; Rosenberg, ML; Scherokman, B, 1989)
"Acute withdrawal is therefore unjustified, but occasional revision of dosage of anti-Parkinsonian drugs is advisable."2.64Benzhexol and side effects with long-acting fluphenazine therapy. ( Crammer, JL; Grove, L, 1972)
"Pediatric movement disorders are a heterogeneous group of symptoms that occur in the context of a large number of different neurological diseases."2.42Pediatric movement disorders. ( Sanger, TD, 2003)
"Classical galactosemia is an autosomal recessive inborn error of metabolism leading to toxic accumulation of galactose and derived metabolites."1.39Movement disorders in adult patients with classical galactosemia. ( Bhatia, KP; Burke, D; Carecchio, M; Chandrashekar, HS; Edwards, MJ; Footitt, EJ; Kojovic, M; Lachmann, RH; Murphy, E; Parees, I; Rubio-Agusti, I, 2013)
"Central pontine and extrapontine myelinolysis (CPEM) are rare conditions usually associated with rapid correction of hyponatremia."1.34Psychotic disorder in a patient with central and extrapontine myelinolysis. ( Krystal, A; Lim, L, 2007)
" Although directly related to daily dosage of levodopa, the myoclonus was specifically blocked by the serotonin antagonist, methysergide."1.25Levodopa-induced myoclonus. ( Bergen, D; Goetz, C; Klawans, HL, 1975)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199036 (80.00)18.7374
1990's4 (8.89)18.2507
2000's2 (4.44)29.6817
2010's3 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bamford, A1
Crowe, BH1
Hacohen, Y1
Lin, JP1
Clarke, A1
Tudor-Williams, G1
Sancho-Shimizu, V1
Vincent, A1
Lim, M1
Pullaperuma, SP1
Ben-Pazi, H1
Rubio-Agusti, I1
Carecchio, M1
Bhatia, KP1
Kojovic, M1
Parees, I1
Chandrashekar, HS1
Footitt, EJ1
Burke, D1
Edwards, MJ1
Lachmann, RH1
Murphy, E1
Sanger, TD1
ABRAMCZUK, J1
DRAPER, IT1
JOHNS, RJ1
Lim, L1
Krystal, A1
Heath, DA1
McGarry, JM1
Nakamura, S1
Akiguchi, I1
Noda, K1
Isozaki, E1
Miyamoto, K1
Hirose, K1
Tanabe, H1
Oda, M1
Weitzman, DO1
Rosfnfeld, C1
Korenyl, C1
Whittier, JR1
Drobný, M1
Adamkov, J1
Svaleková, A1
Fundárek, J1
Ohtomo, E1
Klawans, HL1
Goetz, C1
Bergen, D1
Stimmel, GL1
Sandyk, R1
Fahn, S1
Burke, R1
Stern, Y1
Jabbari, B1
Scherokman, B1
Gunderson, CH1
Rosenberg, ML1
Miller, J1
Yamamoto, K1
Noda, S1
Umezaki, H1
Hirata, I1
Oda, K1
Kuroda, Y1
Shibasaki, H1
Kihara, H1
Valente, M1
Porter, MT1
Fluharty, AL1
Mano, T1
Birket-Smith, E1
Jurna, I2
Lanzer, G1
Theres, C1
Bachmann, T1
Chase, TN1
Bordeleau, JM1
Tétreault, L1
Grove, L1
Crammer, JL1
Klett, CJ1
Caffey, E1
Turek, I1
Kurland, AA1
Hanlon, TE1
Bohm, M1
Wolf, SM1
Crane, GE1
Parkes, JD1
Baxter, RC1
Marsden, CD1
Rees, JE1
Bastecký, J1
Vinar, O1
Taussigová, D1
Villeneuve, A1
Schieferstein, GJ1
Kaufmann, W1
Butz, P1
Wiesendanger, M1
Yaryura-Tobias, JA1
Wolpert, A1
Dana, L1
Merlis, S1
Kline, NS1
Guggenheim, MA1
Dodge, PR1
Weintraub, MI1
Van Woert, MH1
Maller, O1
Heller, S1
Roy, P1
St-Jean, A1
Ban, T1
Noe, W1
Meyer, HH1
Grabowski, K1

Reviews

4 reviews available for trihexyphenidyl and Movement Disorders

ArticleYear
Pediatric movement disorders.
    Current opinion in neurology, 2003, Volume: 16, Issue:4

    Topics: Anticonvulsants; Antiparkinson Agents; Child; Humans; Movement Disorders; Muscle, Skeletal; Trihexyp

2003
[Oral dyskinesis, facial dystonia].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:11

    Topics: Dyskinesia, Drug-Induced; Dystonia; Face; Female; Humans; Levodopa; Male; Meige Syndrome; Mouth; Mov

1993
Antimuscarinic drugs in the treatment of movement disorders.
    Progress in brain research, 1990, Volume: 84

    Topics: Adult; Attention; Dystonia; Humans; Memory; Movement Disorders; Parasympatholytics; Parkinson Diseas

1990
Drug-induced extrapyramidal disorders.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Benztropine; Dihydroxyphenylalanine; Dopa

1972

Trials

3 trials available for trihexyphenidyl and Movement Disorders

ArticleYear
Benzhexol and side effects with long-acting fluphenazine therapy.
    British medical journal, 1972, Jan-29, Volume: 1, Issue:5795

    Topics: Administration, Oral; Adult; Aged; Basal Ganglia Diseases; Clinical Trials as Topic; Female; Fluphen

1972
Evaluating the long-term need for antiparkinson drugs by chronic schizophrenics.
    Archives of general psychiatry, 1972, Volume: 26, Issue:4

    Topics: 1-Propanol; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Benztropine; Biperiden; Chronic Dis

1972
Neutralization of extrapyramidal side-effects with Methixene.
    Diseases of the nervous system, 1971, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Extrapyramidal Tracts; Female; Humans; Male; Middle Age

1971

Other Studies

38 other studies available for trihexyphenidyl and Movement Disorders

ArticleYear
Pediatric Herpes Simplex Virus Encephalitis Complicated by N-Methyl-D-aspartate Receptor Antibody Encephalitis.
    Journal of the Pediatric Infectious Diseases Society, 2015, Volume: 4, Issue:2

    Topics: Acyclovir; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Antiviral Agents; Autoantibodies; Clonid

2015
Trihexyphenidyl improves motor function in children with dystonic cerebral palsy: a retrospective analysis.
    Journal of child neurology, 2011, Volume: 26, Issue:7

    Topics: Adolescent; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infant; Male; Motor Activity; M

2011
Movement disorders in adult patients with classical galactosemia.
    Movement disorders : official journal of the Movement Disorder Society, 2013, Volume: 28, Issue:6

    Topics: Adult; Anti-Dyskinesia Agents; Benzamides; Botulinum Toxins; Brain; Cross-Sectional Studies; Databas

2013
[On the appearance of acathisia during neuroleptic therapy].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1960, Dec-26, Volume: 15

    Topics: Antipsychotic Agents; Chlorpromazine; Humans; Movement; Movement Disorders; Psychiatric Somatic Ther

1960
THE DISORDERED MOVEMENT IN PARKINSONISM AND THE EFFECT OF DRUG TREATMENT.
    Bulletin of the Johns Hopkins Hospital, 1964, Volume: 115

    Topics: Atropine; Dextroamphetamine; Diphenhydramine; Drug Therapy; Geriatrics; Humans; Kinetics; Motor Skil

1964
Psychotic disorder in a patient with central and extrapontine myelinolysis.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Antiparkinson Agents; Antipsychotic Agents; Baclofen; Fema

2007
Phenothiazines in early labour.
    British medical journal, 1967, Feb-11, Volume: 1, Issue:5536

    Topics: Adult; Diagnosis, Differential; Female; Humans; Hyperemesis Gravidarum; Movement Disorders; Perphena

1967
[Rhythmical involuntary movement at rest associated with olivo-ponto-cerebellar atrophy (OPCA)].
    Rinsho shinkeigaku = Clinical neurology, 1993, Volume: 33, Issue:1

    Topics: Adolescent; Aged; Brain; Clonazepam; Electromyography; Female; Humans; Levodopa; Male; Middle Aged;

1993
Quantification of chorea in Huntington's disease by power spectral analysis.
    Diseases of the nervous system, 1976, Volume: 37, Issue:5

    Topics: Adult; Aged; Diazepam; Haloperidol; Humans; Huntington Disease; Mesoridazine; Methods; Middle Aged;

1976
[Therapy of rigidity and hypokinesis in old age using Sinemet].
    Ceskoslovenska neurologie a neurochirurgie, 1979, Volume: 42, Issue:3

    Topics: Aged; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Movement Disorders;

1979
[Oral dyskinesia (author's transl)].
    No to shinkei = Brain and nerve, 1976, Volume: 28, Issue:4

    Topics: Aged; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Masticatory Muscles; Movement Disord

1976
Levodopa-induced myoclonus.
    Archives of neurology, 1975, Volume: 32, Issue:5

    Topics: 5-Hydroxytryptophan; Aged; Amantadine; Amphetamine; Animals; Benztropine; Dopamine Antagonists; Dose

1975
Neuroleptics and the corpus striatum: clinical implications.
    Diseases of the nervous system, 1976, Volume: 37, Issue:4

    Topics: Acetylcholine; Basal Ganglia Diseases; Benztropine; Corpus Striatum; Dopamine; Fluphenazine; Haloper

1976
Alpha-melanocyte-stimulating hormone: possible role in the pathophysiology of acute drug-induced dystonia.
    The International journal of neuroscience, 1990, Volume: 53, Issue:2-4

    Topics: alpha-MSH; Child; Dermatitis, Seborrheic; Dyskinesia, Drug-Induced; Female; Humans; Hydroxyzine; Mov

1990
Treatment of movement disorders with trihexyphenidyl.
    Movement disorders : official journal of the Movement Disorder Society, 1989, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Movement Disorders; Trihexyphenidyl

1989
[Parkinson's disease associated with trihexyphenidyl (THP) induced dysphonia plicae ventricularis].
    Rinsho shinkeigaku = Clinical neurology, 1988, Volume: 28, Issue:4

    Topics: Aged; Female; Humans; Movement Disorders; Parkinson Disease; Sulpiride; Tongue Diseases; Trihexyphen

1988
[Trihexyphenidyl (THP)-induced respiratory dyskinesia].
    Rinsho shinkeigaku = Clinical neurology, 1986, Volume: 26, Issue:2

    Topics: Humans; Male; Middle Aged; Movement Disorders; Respiration Disorders; Trihexyphenidyl

1986
Hyperdibasicaminoaciduria in a mentally retarded homozygote with a peculiar response to phenothiazines.
    Pediatrics, 1973, Volume: 51, Issue:2

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Antipsychotic Agents; Arginine; Chlorpromazine; Cy

1973
[Dyskinesia induced by anticholinergic drugs--electrophysiological analysis].
    Rinsho shinkeigaku = Clinical neurology, 1974, Volume: 14, Issue:3

    Topics: Aged; Benztropine; Biperiden; Electromyography; Female; Humans; Male; Middle Aged; Movement Disorder

1974
Abnormal involuntary movements induced by anticholinergic therapy.
    Acta neurologica Scandinavica, 1974, Volume: 50, Issue:6

    Topics: Aged; Biperiden; Dibenzazepines; Female; Humans; Mastication; Middle Aged; Movement Disorders; Orphe

1974
Inhibition of the effect of reserpine on motor control by drugs which influence reserpine rigidity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 262, Issue:3

    Topics: 1-Propanol; Animals; Atropine; Biperiden; Cyclohexanes; Cyclopentanes; Depression, Chemical; Dihydro

1969
The effect of physostigmine and tetrabenazine on spinal motor control and its inhibition by drugs which influence reserpine rigidity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 263, Issue:3

    Topics: 1-Propanol; Animals; Atropine; Biperiden; Dihydroxyphenylalanine; Electric Stimulation; Electromyogr

1969
[Study of extrapyramidal manifestations induced by neuroleptics].
    Revue canadienne de biologie, 1972, Volume: 31

    Topics: Antiparkinson Agents; Chlorpromazine; Drug Synergism; Extrapyramidal Tracts; Fluphenazine; Haloperid

1972
Tardive dyskinesia: its relation to neuroleptic and antiparkinson drugs.
    The British journal of psychiatry : the journal of mental science, 1972, Volume: 121, Issue:565

    Topics: Aged; Chronic Disease; Female; Humans; Intellectual Disability; Male; Middle Aged; Movement Disorder

1972
Reserpine: cause and treatment of oral-facial dyskinesia.
    Bulletin of the Los Angeles neurological societies, 1973, Volume: 38, Issue:2

    Topics: Deglutition Disorders; Diazepam; Face; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged

1973
Rapid reversal of tardive dyskinesia.
    The American journal of psychiatry, 1973, Volume: 130, Issue:10

    Topics: Adult; Chlorpromazine; Dibenzoxepins; Female; Haloperidol; Humans; Movement Disorders; Neurologic Ma

1973
Comparative trial of benzhexol, amantadine, and levodopa in the treatment of Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:4

    Topics: Aged; Amantadine; Cognition Disorders; Dihydroxyphenylalanine; Drug Therapy, Combination; Edema; Eye

1974
Extrapyramidal symptoms in the course of fluphenazine treatment.
    Activitas nervosa superior, 1972, Volume: 14, Issue:2

    Topics: Adult; Basal Ganglia Diseases; Delayed-Action Preparations; Female; Fluphenazine; Humans; Male; Move

1972
The rabbit syndrome. A peculiar extrapyramidal reaction.
    Canadian Psychiatric Association journal, 1972, Volume: 17, Issue:2

    Topics: Aged; Anxiety; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Fatigue; Female; Humans; Male; M

1972
Central anticholinergic activity of: 2,2-diphenyl-4(3-azabicyclo (3-2-2) non-3-yl) butyramide hydrochloride (SC-13639).
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196, Issue:1

    Topics: Animals; Bridged-Ring Compounds; Central Nervous System; Drug Antagonism; Male; Mice; Motor Activity

1972
[Effect of a combined L-Dopa and decarboxylase inhibitor (Ro 4-4602) therapy in parkinsonism patients. Quantitative analysis of bradykinesia using reaction times].
    Deutsche Zeitschrift fur Nervenheilkunde, 1969, Dec-29, Volume: 197, Issue:1

    Topics: Aged; Carboxy-Lyases; Desipramine; Dihydroxyphenylalanine; Discrimination, Psychological; Drug Syner

1969
Action of L-Dopa in drug induced extrapyramidalism.
    Diseases of the nervous system, 1970, Volume: 31, Issue:1

    Topics: Adult; Chlorpromazine; Chronic Disease; Dihydroxyphenylalanine; Extrapyramidal Tracts; Female; Human

1970
Greater than recommended drug dosages--some effects.
    The American journal of psychiatry, 1970, Volume: 126, Issue:12

    Topics: Adult; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Movement Disorders; Procyclidine;

1970
Unusual arm movements with onset in childhood--a nosologic entity?
    Transactions of the American Neurological Association, 1970, Volume: 95

    Topics: Child; Diagnosis, Differential; Diazepam; Dihydroxyphenylalanine; Diphenhydramine; Dystonia Musculor

1970
Reversal by levodopa of cholinergic hypersensitivity in Parkinson's disease.
    The New England journal of medicine, 1971, Feb-25, Volume: 284, Issue:8

    Topics: Brain; Dihydroxyphenylalanine; Dopamine; Drug Hypersensitivity; Female; Handwriting; Humans; Injecti

1971
Studies with antiparkinsonian drugs with chronic psychiatric patients.
    International journal of neuropsychiatry, 1966, Volume: 2, Issue:1

    Topics: Adult; Aged; Chlorpromazine; Extrapyramidal Tracts; Humans; Mental Disorders; Middle Aged; Movement

1966
[On the question of possible irreversible disorders due to psychopharmacotherapy].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1966, Volume: 208, Issue:4

    Topics: Adult; Autonomic Nervous System; Biperiden; Butyrophenones; Central Nervous System; Chlorpromazine;

1966
[Prolonged use of ponalid in extapyramidal drug-induced syndromes].
    Neurologia, neurochirurgia i psychiatria polska, 1966, Volume: 16, Issue:12

    Topics: Humans; Movement Disorders; Parkinson Disease; Parkinson Disease, Secondary; Salivary Gland Diseases

1966