trihexyphenidyl has been researched along with Hepatolenticular Degeneration in 5 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cocco, GA | 1 |
| Loudianos, G | 1 |
| Pes, GM | 1 |
| Tolu, F | 1 |
| Lepori, MB | 1 |
| Barrocu, M | 1 |
| Sechi, GP | 1 |
| Aravind, VK | 1 |
| Krishnaram, VD | 1 |
| Neethiarau, V | 1 |
| Srinivasan, KG | 1 |
| Verma, R | 1 |
| Lalla, R | 1 |
| Patil, TB | 1 |
| Chan, KH | 1 |
| Cheung, RT | 1 |
| Au-Yeung, KM | 1 |
| Mak, W | 1 |
| Cheng, TS | 1 |
| Ho, SL | 1 |
| Hirabayashi, S | 1 |
| Kanda, H | 1 |
| Tsuno, T | 1 |
| Akabane, T | 1 |
| Oguchi, K | 1 |
| Yanagisawa, N | 1 |
5 other studies available for trihexyphenidyl and Hepatolenticular Degeneration
| Article | Year |
|---|---|
"Acquired" hepatocerebral degeneration in a patient heterozygote carrier for a novel mutation in ATP7B gene.
Topics: Adenosine Triphosphatases; Adult; Amino Acid Substitution; Basal Ganglia; Cation Transport Proteins; | 2009 |
Wilson's disease--a rare psychiatric presentation.
Topics: Adrenergic Uptake Inhibitors; Adult; Basal Ganglia Diseases; Diagnosis, Differential; Hepatolenticul | 2009 |
Is blinking of the eyes affected in extrapyramidal disorders? An interesting observation in a patient with Wilson disease.
Topics: Adult; Antiparkinson Agents; Basal Ganglia Diseases; Blinking; Carbidopa; Ceruloplasmin; Drug Therap | 2012 |
Wilson's disease with depression and parkinsonism.
Topics: Adult; Antiparkinson Agents; Brain; Bromocriptine; Chelating Agents; Depressive Disorder; Female; He | 2005 |
[Effects of high-dosage trihexyphenidyl on symptomatic dystonia in a case of Wilson disease].
Topics: Adolescent; Dysarthria; Dystonia; Hepatolenticular Degeneration; Humans; Male; Trihexyphenidyl | 1985 |