trihexyphenidyl and Diseases, Occupational

trihexyphenidyl has been researched along with Diseases, Occupational in 1 studies

Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.

Research

Studies (1)

Authors

Clinical Trials (2)

Trial Overview

Trial Outcomes

Change in Perceived Stress Scale (PSS)

Patient reported outcomes measured by questionnaires that address adverse events and the impact of quality of life using the perceived stress scale. A 10-item questionnaire, each item scored 0 (never) to 4 (very often), full scale from 0-40, with higher score indicating higher perceived stress. the more often the person perceives stress Change in PSS at week 8 compared to baseline (NCT02107261)
Timeframe: baseline and at 8 weeks

Change in Medical Research Council (MRC) Scale

"Motor strength using a dynamometer of the finger/wrist/elbow flexors to document any treatment induced weakness.~Scale from 0-4, higher score indicates poorer health outcomes." (NCT02107261)
Timeframe: baseline and at 8 weeks

Change in Motor Strength Comparison

"Motor strength tested using a dynamometer to document any weakness the treatment may produce as compared to the baseline visit and 8 weeks.~Dynamometer (DYN) - is a mechanical device that measures the pounds of force that a muscle exerts, Grip - a device that measures grip strength, and finger flexors digit 2 and 3 (FF d2-3). These measures are the amount of lbs of force exert. The higher number is the highest exerted out of 3 tries." (NCT02107261)
Timeframe: baseline and at 8 weeks

Physician Global Perception of Change - Blinded Rater 1

The principal outcome measure was improvement in musical performance, measured by blinded rater, using physician global perception of change at post treatment compared to at 8 weeks. Categories are very much improved, much improved, minimal improved, no change, and minimal worse. (NCT02107261)
Timeframe: at visit 4 (week 8)

Physician Global Perception of Change - Blinded Rater 2

The principal outcome measure was improvement in musical performance, measured by blinded rater, using physician global perception of change at post treatment compared to at 8 weeks. Categories are very much improved, much improved, minimal improved, no change, and minimal worse. (NCT02107261)
Timeframe: at visit 4 (week 8)

Rating of Overall Musical Performance - Blinded Rater 1

"Rating of overall musical performance based on comparison to baseline video at week 8.~Rating from +3, very much improved to -3, very much worse. Higher score indicates more improvement." (NCT02107261)
Timeframe: baseline and at 8 weeks

Rating of Overall Musical Performance - Blinded Rater 2

"Rating of overall musical performance based on comparison to baseline video at week 8.~Best Overall Musical Performance on 7 point scale from +3 Very much improved to -3 Very much worse. Higher score indicates more improvement." (NCT02107261)
Timeframe: baseline and week 8

Reviews

1 review available for trihexyphenidyl and Diseases, Occupational