trihexyphenidyl has been researched along with Dementia Praecox in 90 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventeen patients with schizophrenia who had been free of medication for at least 2 months entered a placebo-controlled, random-order crossover trial of 5 mg of trihexyphenidyl twice daily for 4 weeks." | 9.07 | A placebo-controlled trial of trihexyphenidyl in unmedicated patients with schizophrenia. ( Amico, E; Ciraulo, D; Dreyfuss, D; Goff, DC, 1994) |
| " Case description A 49-year-old man with schizophrenia, who was under maintenance treatment with olanzapine 20 mg/day, trihexyphenidyl 4 mg/day, and trazodone 50 mg/day, suffered from heat stroke in a heat wave and required intensive care." | 7.81 | Heat stroke during treatment with olanzapine, trihexyphenidyl, and trazodone in a patient with schizophrenia. ( Chang, CM; Chen, PJ; Lee, CP, 2015) |
| "Here is a case of a woman with schizophrenia who developed rhabdomyolysis following overdose of risperidone, trihexyphenidyl and benzodiazepines." | 7.80 | Multidrug overdose-induced myoclonus complicated by rhabdomyolysis: possible role and mechanism of muscle toxicity of risperidone. ( Hsu, YC; Yeh, YW, 2014) |
| "The purpose of this study was to assess the effects of an anticholinergic (trihexyphenidyl) antiparkinsonian medication on the Mini-Mental State Examination (MMSE) and the Cambridge Cognitive Examination (CAMCOG) scores in long-term institutionalized elderly patients with schizophrenia." | 7.70 | Effects of trihexyphenidyl on MMSE and CAMCOG scores of medicated elderly patients with schizophrenia. ( Heinik, J, 1998) |
| "Seventeen patients with schizophrenia who had been free of medication for at least 2 months entered a placebo-controlled, random-order crossover trial of 5 mg of trihexyphenidyl twice daily for 4 weeks." | 5.07 | A placebo-controlled trial of trihexyphenidyl in unmedicated patients with schizophrenia. ( Amico, E; Ciraulo, D; Dreyfuss, D; Goff, DC, 1994) |
| "A double-blind study was carried out on the therapeutic effects of dexetimide and artane in the control of neuroleptic-induced extrapyramidal side-effects in 261 cases of schizophrenia." | 5.07 | [A double-blind study on the effect of dexetimide in the control of neuroleptic-induced extrapyramidal side-effects]. ( Chen, Y, 1991) |
| " Case description A 49-year-old man with schizophrenia, who was under maintenance treatment with olanzapine 20 mg/day, trihexyphenidyl 4 mg/day, and trazodone 50 mg/day, suffered from heat stroke in a heat wave and required intensive care." | 3.81 | Heat stroke during treatment with olanzapine, trihexyphenidyl, and trazodone in a patient with schizophrenia. ( Chang, CM; Chen, PJ; Lee, CP, 2015) |
| "Here is a case of a woman with schizophrenia who developed rhabdomyolysis following overdose of risperidone, trihexyphenidyl and benzodiazepines." | 3.80 | Multidrug overdose-induced myoclonus complicated by rhabdomyolysis: possible role and mechanism of muscle toxicity of risperidone. ( Hsu, YC; Yeh, YW, 2014) |
| "The purpose of this study was to assess the effects of an anticholinergic (trihexyphenidyl) antiparkinsonian medication on the Mini-Mental State Examination (MMSE) and the Cambridge Cognitive Examination (CAMCOG) scores in long-term institutionalized elderly patients with schizophrenia." | 3.70 | Effects of trihexyphenidyl on MMSE and CAMCOG scores of medicated elderly patients with schizophrenia. ( Heinik, J, 1998) |
| "Plasma chlorpromazine (CPZ) levels of 50 psychotic inpatients were measured by gas liquid chromatography; the clinical progress of 29 of these patients with acute psychoses was also assessed." | 3.65 | Clinical response and plasma levels: effect of dose, dosage schedules, and drug interactions on plasma chlorpromazine levels. ( Lasagna, L; Nasrallah, H; Rivera-Calimlim, L; Strauss, J, 1976) |
| "Twenty-one chronic schizophrenics were stabilized with chlorpromazine therapy at their therapeutic dosage for one month." | 2.65 | Effect of antiparkinsonian medication on plasma levels of chlorpromazine. ( Bark, N; Cooper, TB; Lee, JH; Simpson, GM; Sud, I, 1980) |
| "Trihexyphenidyl is a synthetic anticholinergic used in psychiatric patient for the relief of neuroleptic-induced extrapyramidal symptoms." | 1.29 | Trihexyphenidyl abuse in schizophrenic patient: a case report. ( Lo, Y; Tsai, SJ, 1996) |
| " In this study, 44 clinically stable schizophrenic inpatients were administered a battery of neuropsychological tests, and their performance was correlated with dosage of neuroleptic medication and benztropine." | 1.28 | Relationships between medication treatments and neuropsychological test performance in schizophrenia. ( Haas, GL; Hill, J; Keilp, JG; Sweeney, JA; Weiden, PJ, 1991) |
| " The trihexphenidyl-induced increase in CPZ plasma levels was independent of CPZ oral dosage and of CPZ plasma levels." | 1.28 | Effects of trihexyphenidyl on plasma chlorpromazine in young schizophrenics. ( Cooper, T; Rockland, L; Schwartz, F; Sullivan, T; Weber, D, 1990) |
| " Of 24 placebo patients 9 left the study early because of adverse effects; none of the 8 patients in the antiparkinsonian group did so." | 1.26 | Adverse effects of antiparkinson drug withdrawal. ( Cole, JO; Gardos, G; Jellinek, T, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 61 (67.78) | 18.7374 |
| 1990's | 19 (21.11) | 18.2507 |
| 2000's | 7 (7.78) | 29.6817 |
| 2010's | 3 (3.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsu, YC | 1 |
| Yeh, YW | 1 |
| Guru, S | 1 |
| Vanamoorthy, U | 1 |
| Loganathan, S | 2 |
| Varghese, M | 2 |
| Lee, CP | 1 |
| Chen, PJ | 1 |
| Chang, CM | 1 |
| Rao, NP | 1 |
| Prakash, O | 1 |
| Aggarwal, A | 1 |
| Garg, A | 1 |
| Jiloha, RC | 1 |
| Suzuki, E | 1 |
| Obata, M | 1 |
| Yoshida, Y | 1 |
| Miyaoka, H | 1 |
| RASHKIS, HA | 1 |
| SMARR, ER | 1 |
| STJEAN, A | 1 |
| DONALD, M | 1 |
| BAN, TA | 2 |
| Kwok, JS | 1 |
| Chan, TY | 1 |
| Thomsen, M | 1 |
| Wörtwein, G | 1 |
| Fink-Jensen, A | 1 |
| Woldbye, DP | 1 |
| Wess, J | 1 |
| Caine, SB | 1 |
| Bhatia, MS | 1 |
| Gupta, R | 1 |
| Dhawan, J | 1 |
| McIlrath, WA | 1 |
| Warnes, H | 1 |
| Manos, N | 2 |
| Gkiouzepas, J | 2 |
| Logothetis, J | 1 |
| Jellinek, T | 2 |
| Gardos, G | 1 |
| Cole, JO | 1 |
| Bennie, EH | 1 |
| Ungvári, G | 1 |
| Bitter, I | 1 |
| Czobor, P | 1 |
| Vitrai, J | 1 |
| Pethö, B | 1 |
| Smirnov, VK | 1 |
| Kua, EH | 1 |
| Ang, PC | 1 |
| Siew, HC | 1 |
| Pullen, GP | 1 |
| Best, NR | 1 |
| Maguire, J | 1 |
| Crawshaw, JA | 1 |
| Mullen, PE | 1 |
| Irwin, GE | 1 |
| Simon, JE | 1 |
| Izvol'skiĭ, SA | 1 |
| Saito, M | 1 |
| Kita, S | 1 |
| Kagono, Y | 1 |
| Suitsu, N | 1 |
| Honda, Y | 1 |
| Simpson, GM | 2 |
| Cooper, TB | 1 |
| Bark, N | 1 |
| Sud, I | 1 |
| Lee, JH | 1 |
| Tandon, R | 3 |
| Dequardo, JR | 1 |
| Gall, JA | 1 |
| Drummer, OH | 1 |
| Landgren, AJ | 1 |
| de Leon, J | 1 |
| Stanilla, JK | 1 |
| White, AO | 1 |
| Goff, DC | 1 |
| Amico, E | 1 |
| Dreyfuss, D | 1 |
| Ciraulo, D | 1 |
| Lo, Y | 1 |
| Tsai, SJ | 1 |
| Zemishlany, Z | 1 |
| Aizenberg, D | 1 |
| Weiner, Z | 1 |
| Weizman, A | 3 |
| Spivak, B | 2 |
| Gonen, N | 2 |
| Mester, R | 2 |
| Averbuch, E | 1 |
| Adlersberg, S | 2 |
| Liao, WB | 1 |
| Bullard, MJ | 1 |
| Kuo, CT | 1 |
| Hsiao, CT | 1 |
| Chu, PH | 1 |
| Chiang, CW | 1 |
| Otani, K | 1 |
| Ishida, M | 1 |
| Yasui, N | 1 |
| Kondo, T | 1 |
| Mihara, K | 1 |
| Suzuki, A | 1 |
| Kaneko, S | 1 |
| Inoue, Y | 1 |
| Shibata, M | 1 |
| Ikeda, K | 1 |
| Rosen, L | 1 |
| Heinik, J | 1 |
| Salganik, I | 1 |
| Chong, SA | 1 |
| Remington, G | 1 |
| Tan, CH | 1 |
| Wang, HC | 1 |
| Hsieh, Y | 1 |
| Rivera-Calimlim, L | 1 |
| Nasrallah, H | 1 |
| Strauss, J | 1 |
| Lasagna, L | 1 |
| Kolakowska, T | 1 |
| Wiles, DH | 1 |
| Gelder, MG | 1 |
| McNeilly, AS | 1 |
| Ringwald, E | 1 |
| Singh, MM | 4 |
| Kay, SR | 3 |
| Garelis, E | 1 |
| Gillin, JC | 1 |
| Wyatt, RJ | 1 |
| Neff, N | 1 |
| Borison, RL | 1 |
| Havdala, HS | 1 |
| Diamond, BI | 1 |
| Storrie, MC | 1 |
| Scher, M | 1 |
| McGuire, J | 1 |
| Bokan, J | 1 |
| Crow, TJ | 1 |
| Johnstone, EC | 1 |
| McClelleand, HA | 1 |
| Simeon, J | 1 |
| Itil, TM | 1 |
| Elmore, JL | 1 |
| Sugerman, AA | 1 |
| Stimmel, GL | 1 |
| Sweeney, JA | 1 |
| Keilp, JG | 1 |
| Haas, GL | 1 |
| Hill, J | 1 |
| Weiden, PJ | 1 |
| Chen, Y | 1 |
| Deshmukh, DK | 1 |
| Joshi, VS | 1 |
| Agarwal, MR | 1 |
| Schifano, F | 1 |
| di Costanzo, E | 1 |
| Rockland, L | 1 |
| Cooper, T | 1 |
| Schwartz, F | 1 |
| Weber, D | 1 |
| Sullivan, T | 1 |
| Hidalgo, HA | 1 |
| Mowers, RM | 1 |
| Lee, TH | 1 |
| Tang, LM | 1 |
| Trend, P | 1 |
| Trimble, M | 1 |
| Wessely, S | 1 |
| Kok, LP | 1 |
| Christopher, YS | 1 |
| Hitri, A | 2 |
| Craft, RB | 2 |
| Fallon, J | 1 |
| Sethi, R | 2 |
| Sinha, D | 2 |
| Fayen, M | 1 |
| Goldman, MB | 1 |
| Moulthrop, MA | 1 |
| Luchins, DJ | 1 |
| Hermesh, H | 1 |
| Molcho, A | 1 |
| Munitz, H | 1 |
| Fennig, S | 1 |
| Levine, Y | 1 |
| Naisberg, S | 1 |
| Elizur, A | 1 |
| Greden, JF | 1 |
| Silk, KR | 1 |
| Greden, J | 1 |
| Opler, LA | 1 |
| Fisch, RZ | 1 |
| Dusek, K | 1 |
| Seeman, MV | 1 |
| Denber, HC | 1 |
| Goldner, F | 1 |
| Gol'dovskaia, IL | 1 |
| Klett, CJ | 1 |
| Caffey, E | 1 |
| Smith, JM | 1 |
| Freeman, H | 1 |
| Mehta, IS | 1 |
| Turek, I | 1 |
| Kurland, AA | 1 |
| Hanlon, TE | 1 |
| Bohm, M | 1 |
| Crane, GE | 1 |
| Gravel, LL | 1 |
| Bédard, P | 1 |
| Frenette, M | 1 |
| Hillel, J | 1 |
| Albert, JM | 1 |
| Bastecký, J | 1 |
| Vinar, O | 1 |
| Taussigová, D | 1 |
| Man, PL | 1 |
| Aleem, A | 1 |
| Villeneuve, A | 1 |
| Pecknold, JC | 1 |
| Ananth, JV | 1 |
| Lehmann, HE | 1 |
| Naviau, J | 1 |
| Yaryura-Tobias, JA | 1 |
| Wolpert, A | 1 |
| Dana, L | 1 |
| Merlis, S | 1 |
| Kline, NS | 1 |
| Minns, RA | 1 |
| Castaldo, V | 1 |
| Magalif, AIu | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prevalence Study of Sialorrhea in Inpatients and Outpatients Treated With Clozapine[NCT04197037] | 129 participants (Actual) | Observational | 2018-03-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 trials available for trihexyphenidyl and Dementia Praecox
| Article | Year |
|---|---|
Discontinuing antiparkinson medication in chronic schizophrenics. At what cost to the patient?
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chronic Disease; Clinical Trials as Topic; Double-Blin | 1981 |
Effect of antiparkinsonian medication on plasma levels of chlorpromazine.
Topics: Chlorpromazine; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Mal | 1980 |
A placebo-controlled trial of trihexyphenidyl in unmedicated patients with schizophrenia.
Topics: Adult; Attitude to Health; Double-Blind Method; Female; Humans; Male; Placebos; Psychiatric Status R | 1994 |
No effect of the anticholinergic drugs trihexyphenidyl and biperiden on the plasma concentrations of bromperidol and its reduced metabolite.
Topics: Adult; Biperiden; Drug Interactions; Female; Haloperidol; Humans; Male; Middle Aged; Schizophrenia; | 1997 |
Trihexyphenidyl treatment of clozapine-induced hypersalivation.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Humans; Male; Muscarinic Antagonists; Schizophrenia; | 1997 |
Clinical significance of plasma chlorpromazine levels. II. Plasma levels of the drug, some of its metabolites and prolactin in patients receiving long-term phenothiazine treatment.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Drug Tolerance; Female; Humans; Male; Middle Aged; Park | 1976 |
[Dopamine-receptor stimulators and neuroleptic-induced dyskinesia (author's transl)].
Topics: Antipsychotic Agents; Bromocriptine; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Humans; Lev | 1978 |
A longitudinal therapeutic comparison between two prototypic neuroleptics (haloperidol and chlorpromazine) in matched groups of schizophrenics. Nontherapeutic interactions with trihexyphenidyl. Theoretical implications for potency differences.
Topics: Adult; Affect; Antiparkinson Agents; Arousal; Chlorpromazine; Clinical Trials as Topic; Dose-Respons | 1975 |
[A double-blind study on the effect of dexetimide in the control of neuroleptic-induced extrapyramidal side-effects].
Topics: Adolescent; Adult; Antipsychotic Agents; Dexetimide; Double-Blind Method; Female; Humans; Male; Midd | 1991 |
Serum neuroleptic and anticholinergic activity in relationship to cognitive toxicity of antiparkinsonian agents in schizophrenic patients.
Topics: Adult; Amantadine; Antipsychotic Agents; Benztropine; Drug Interactions; Humans; Male; Memory; Middl | 1987 |
Differential memory function with dopaminergic versus anticholinergic treatment of drug-induced extrapyramidal symptoms.
Topics: Adult; Amantadine; Antipsychotic Agents; Cerebral Ventricles; Clinical Trials as Topic; Dilatation, | 1988 |
The effect of trihexphenidyl (Artane) on memory in schizophrenic patients.
Topics: Adult; Clinical Trials as Topic; Depression; Humans; Memory; Middle Aged; Neuropsychological Tests; | 1987 |
Evaluating the long-term need for antiparkinson drugs by chronic schizophrenics.
Topics: 1-Propanol; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Benztropine; Biperiden; Chronic Dis | 1972 |
Sleeplessness in acute and chronic schizophrenia--response to haloperidol and anti-parkinsonism agents.
Topics: Acute Disease; Adult; Antiparkinson Agents; Arousal; Benztropine; Chronic Disease; Clinical Trials a | 1973 |
A double-blind comparison of the efficacy of EX 10-029 and trihexyphenidyl hydrochloride in relieving drug-induced Parkinsonian symptoms.
Topics: Antiparkinson Agents; Clinical Trials as Topic; Female; Humans; Male; Methods; Middle Aged; Parkinso | 1972 |
75 other studies available for trihexyphenidyl and Dementia Praecox
| Article | Year |
|---|---|
Multidrug overdose-induced myoclonus complicated by rhabdomyolysis: possible role and mechanism of muscle toxicity of risperidone.
Topics: Antipsychotic Agents; Benzodiazepines; Drug Overdose; Female; Humans; Middle Aged; Myoclonus; Rhabdo | 2014 |
Neuroleptic malignant syndrome following abrupt anti-cholinergic withdrawal: a case report.
Topics: Antipsychotic Agents; Cholinergic Antagonists; Female; Humans; Lorazepam; Neuroleptic Malignant Synd | 2014 |
Heat stroke during treatment with olanzapine, trihexyphenidyl, and trazodone in a patient with schizophrenia.
Topics: Amisulpride; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Body Temperature Regulatio | 2015 |
Use of electroconvulsive therapy for schizophrenia with comorbid Marfan syndrome.
Topics: Adult; Antipsychotic Agents; Catatonia; Electroconvulsive Therapy; Female; Humans; Marfan Syndrome; | 2009 |
Trihexyphenidyl (benzhexol) in clozapine-induced nocturnal enuresis and sialorrhea.
Topics: Amitriptyline; Antipsychotic Agents; Clozapine; Humans; Male; Muscarinic Antagonists; Nocturnal Enur | 2009 |
Tardive dyskinesia with risperidone and anticholinergics.
Topics: Adult; Biperiden; Cholinergic Antagonists; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Fema | 2002 |
Drug and milieu effects with chronic schizophrenics.
Topics: Amobarbital; Catatonia; Methylphenidate; Reserpine; Schizophrenia; Trihexyphenidyl | 1957 |
INTERCHANGEABLITY OF ANTIPARKINSONIAN MEDICATION.
Topics: Antiparkinson Agents; Biomedical Research; Extrapyramidal Tracts; Geriatrics; Humans; Parasympatholy | 1964 |
Recurrent heat-related illnesses during antipsychotic treatment.
Topics: Antipsychotic Agents; Body Temperature Regulation; Chlorpromazine; Clopenthixol; Diabetes Complicati | 2005 |
Decreased prepulse inhibition and increased sensitivity to muscarinic, but not dopaminergic drugs in M5 muscarinic acetylcholine receptor knockout mice.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Cocaine; Dextroamphetamine; Dopamine Ago | 2007 |
Myocarditis after overdose of conventional antipsychotics.
Topics: Aged; Antipsychotic Agents; Blood Pressure; Chlorpromazine; Creatine Kinase; Dopamine; Drug Overdose | 2009 |
Experience with a depot phenothiazine in the treatment of schizophrenia.
Topics: Adult; Aged; Female; Fluphenazine; Humans; Male; Middle Aged; Schizophrenia; Trihexyphenidyl | 1967 |
Toxic psychosis due to antiparkinsonian drugs.
Topics: Adolescent; Adult; Bipolar Disorder; Female; Humans; Male; Middle Aged; Paranoid Disorders; Parasymp | 1967 |
The need for continuous use of antiparkinsonian medication with chronic schizophrenic patients receiving long-term neuroleptic therapy.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Dyskin | 1981 |
Adverse effects of antiparkinson drug withdrawal.
Topics: Antiparkinson Agents; Antipsychotic Agents; Benztropine; Biperiden; Double-Blind Method; Drug Therap | 1981 |
Antiparkinsonian medication in depressed schizophrenics on depot neuroleptics.
Topics: Antipsychotic Agents; Humans; Procyclidine; Pyrrolidines; Schizophrenia; Trihexyphenidyl | 1982 |
[The role of high-dosage neuroleptic therapy and electroshock in the treatment of the acute phase of schizophrenia].
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Dose-Response Relationship, Drug; Electroconvul | 1981 |
[Status of microhemodynamics and features of capillary permeability in schizophrenia].
Topics: Adult; Capillary Permeability; Diphenhydramine; Ethinyl Estradiol; Female; Haloperidol; Histamine H1 | 1982 |
Tardive dyskinesia in chronic schizophrenic inpatients.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle | 1982 |
Anticholinergic drug abuse: a common problem?
Topics: Adult; Biperiden; Female; Humans; Male; Middle Aged; Orphenadrine; Parasympatholytics; Schizophrenia | 1984 |
A study of benzhexol abuse.
Topics: Adolescent; Adult; Female; Hallucinations; Humans; Illusions; Male; Personality Disorders; Schizophr | 1984 |
Neuroleptic malignant syndrome.
Topics: Basal Ganglia Diseases; Chronic Disease; Diagnosis, Differential; Dibenzoxazepines; Dose-Response Re | 1984 |
[Protracted psychoses in juvenile psychopath-like heboid schizophrenia (atypical variant of its course)].
Topics: Adolescent; Adult; Antisocial Personality Disorder; Female; Humans; Male; Opioid-Related Disorders; | 1983 |
Computerized EEG study on drug-induced extrapyramidalism in schizophrenic patients.
Topics: Adolescent; Amantadine; Brain; Computers; Electroencephalography; Female; Glycolates; Haloperidol; H | 1982 |
Treatment of schizophrenia with anticholinergic medications.
Topics: Acute Disease; Biperiden; Cholinergic Antagonists; Controlled Clinical Trials as Topic; Dopamine; Do | 1995 |
Death due to benzhexol toxicity.
Topics: Bronchopneumonia; Cause of Death; Death, Sudden; Dyskinesia, Drug-Induced; Empyema, Pleural; Fatal O | 1995 |
Anticholinergics to treat clozapine withdrawal.
Topics: Adult; Clozapine; Female; Humans; Male; Schizophrenia; Substance Withdrawal Syndrome; Trihexyphenidy | 1994 |
Trihexyphenidyl abuse in schizophrenic patient: a case report.
Topics: Adult; Humans; Male; Parasympatholytics; Schizophrenia; Substance-Related Disorders; Trihexyphenidyl | 1996 |
Trihexyphenidyl (Artane) abuse in schizophrenic patients.
Topics: Adult; Antiparkinson Agents; Brief Psychiatric Rating Scale; Female; Hospitals, Psychiatric; Humans; | 1996 |
Neuroleptic malignant syndrome associated with abrupt withdrawal of anticholinergic agents.
Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Fluphenazine; Humans; Male; Muscarinic Ant | 1996 |
Anticholinergic overdose induced torsade de pointes successfully treated with verapamil.
Topics: Adolescent; Antidepressive Agents; Antipsychotic Agents; Cholinergic Antagonists; Drug Overdose; Fem | 1996 |
Effects of trihexyphenidyl on MMSE and CAMCOG scores of medicated elderly patients with schizophrenia.
Topics: Aged; Analysis of Variance; Anti-Dyskinesia Agents; Antipsychotic Agents; Cognition; Cross-Sectional | 1998 |
[The release of growth hormone in response to injection of trihexiphenidyl in patients with Alzheimer's disease, multi infarction dementia and in schizophrenic patients with intact cognitive functions (preliminary results)].
Topics: Aged; Alzheimer Disease; Brain; Cholinergic Antagonists; Cognition; Dementia, Multi-Infarct; Diagnos | 1999 |
Risperidone treatment of tardive dyskinesia and dystonia.
Topics: Antipsychotic Agents; Diazepam; Dopamine Antagonists; Drug Administration Schedule; Drug Therapy, Co | 1999 |
Treatment of neuroleptic malignant syndrome with subcutaneous apomorphine monotherapy.
Topics: Adult; Apomorphine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Co | 2001 |
Clinical response and plasma levels: effect of dose, dosage schedules, and drug interactions on plasma chlorpromazine levels.
Topics: Acute Disease; Adolescent; Adult; Aged; Bipolar Disorder; Brief Psychiatric Rating Scale; Chlorproma | 1976 |
Therapeutic antagonism between anticholinergic antiparkinsonism agents and neuroleptics in schizophrenia. Implications for a neuropharmacological model.
Topics: Antiparkinson Agents; Antipsychotic Agents; Benztropine; Chlorpromazine; Drug Therapy, Combination; | 1979 |
Elevated blood serotonin concentrations in unmediated chronic schizophrenic patients: a preliminary study.
Topics: Adolescent; Adult; Amitriptyline; Antipsychotic Agents; Benztropine; Blood Cell Count; Blood Platele | 1975 |
A new animal model for schizophrenia: cholinergic and serotonergic modulation.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Dextroamphetamine; Disease Models, Animal; Dose-Resp | 1978 |
Thrombocytopenia in the absence of leukopenia associated with the use of neuroleptics.
Topics: Adult; Benztropine; Chlorpromazine; Haloperidol; Humans; Male; Perphenazine; Schizophrenia; Thalasse | 1978 |
Mood elevating effect of trihexyphenidyl and biperiden in individuals taking antipsychotic medication.
Topics: Adolescent; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Biperiden; Emotions; Euphoria; Fema | 1977 |
The coincidence of schizophrenia and Parkinsonism: some neurochemical implications.
Topics: Aged; Delusions; Dopamine; Female; Hallucinations; Humans; Middle Aged; Parkinson Disease, Postencep | 1976 |
Computerized Electroencephalogram. A model of understanding the brain function in childhood psychosis and its treatment.
Topics: Acoustic Stimulation; Adolescent; Autistic Disorder; Brain; Child; Child, Preschool; Diagnosis, Comp | 1975 |
Precipitation of psychosis during electroshock therapy.
Topics: Adult; Chlorpromazine; Depression; Diagnosis, Differential; Drug Therapy, Combination; Electroconvul | 1975 |
Neuroleptics and the corpus striatum: clinical implications.
Topics: Acetylcholine; Basal Ganglia Diseases; Benztropine; Corpus Striatum; Dopamine; Fluphenazine; Haloper | 1976 |
Relationships between medication treatments and neuropsychological test performance in schizophrenia.
Topics: Adult; Antipsychotic Agents; Benztropine; Dose-Response Relationship, Drug; Drug Therapy, Combinatio | 1991 |
Rabbit syndrome--a rare complication of long-term neuroleptic medication.
Topics: Administration, Oral; Antipsychotic Agents; Diagnosis, Differential; Dyskinesia, Drug-Induced; Human | 1990 |
Excessive use of anticholinergic drugs in a sub-sample of Italian schizophrenics.
Topics: Adult; Biperiden; Female; Humans; Italy; Male; Middle Aged; Orphenadrine; Parasympatholytics; Patien | 1991 |
Effects of trihexyphenidyl on plasma chlorpromazine in young schizophrenics.
Topics: Adolescent; Adult; Chlorpromazine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fema | 1990 |
Anticholinergic drug abuse.
Topics: Adult; Affect; Benztropine; Female; Humans; Male; Middle Aged; Parasympatholytics; Schizophrenia; Su | 1990 |
Neuroleptic malignant syndrome.
Topics: Amylases; Haloperidol; Humans; Lipase; Male; Middle Aged; Neuroleptic Malignant Syndrome; Schizophre | 1988 |
Schizophrenic psychosis associated with benzhexol (artane) therapy.
Topics: Adult; Female; Humans; Schizophrenia; Torticollis; Trihexyphenidyl | 1989 |
Tardive dyskinesia in schizophrenic outpatients.
Topics: Adolescent; Adult; Age Factors; Antipsychotic Agents; Child; Dyskinesia, Drug-Induced; Electroconvul | 1985 |
Drug levels and antiparkinsonian drugs in neuroleptic-treated schizophrenic patients.
Topics: Adult; Amantadine; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; | 1987 |
Successful propranolol therapy for neuroleptic-induced akathisia resistant to anticholinergic and benzodiazepine drugs.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Diazepam; Female; Humans; Male; Propranolol; P | 1988 |
Treatment of negative schizophrenic symptoms with trihexyphenidyl.
Topics: Female; Humans; Male; Middle Aged; Schizophrenia; Trihexyphenidyl | 1988 |
Variety of effects of trihexyphenidyl (THP) on schizophrenic and non-schizophrenic abusers.
Topics: Humans; Schizophrenia; Schizophrenic Psychology; Substance-Related Disorders; Trihexyphenidyl | 1987 |
Anticholinergic-neuroleptic antagonism in terms of positive and negative symptoms of schizophrenia: implications for psychobiological subtyping.
Topics: Adolescent; Adult; Benztropine; Chlorpromazine; Drug Therapy, Combination; Female; Haloperidol; Huma | 1987 |
Trihexyphenidyl abuse: therapeutic implications for negative symptoms of schizophrenia?
Topics: Adult; Borderline Personality Disorder; Dose-Response Relationship, Drug; Female; Hallucinations; Hu | 1987 |
[Preventive administration of Triphenidyl in Majeptil therapy].
Topics: Adolescent; Adult; Humans; Male; Middle Aged; Phenothiazines; Schizophrenia; Trihexyphenidyl | 1966 |
Paradoxical effects of phenothiazines.
Topics: Adult; Amitriptyline; Chlorpromazine; Diazepam; Female; Humans; Meclofenoxate; Meprobamate; Phenothi | 1968 |
[The possibilities and limitations of psychotropic drug therapy for patients with glaucoma].
Topics: Aged; Alcoholism; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Chronic Disease; Dementia; | 1974 |
Tardive dyskinesia: its relation to neuroleptic and antiparkinson drugs.
Topics: Aged; Chronic Disease; Female; Humans; Intellectual Disability; Male; Middle Aged; Movement Disorder | 1972 |
Rapid reversal of tardive dyskinesia.
Topics: Adult; Chlorpromazine; Dibenzoxepins; Female; Haloperidol; Humans; Movement Disorders; Neurologic Ma | 1973 |
[Home treatment in the Bayonne community].
Topics: Adult; Amitriptyline; Costs and Cost Analysis; Depression; Family; Family Therapy; Female; Fluphenaz | 1973 |
Extrapyramidal symptoms in the course of fluphenazine treatment.
Topics: Adult; Basal Ganglia Diseases; Delayed-Action Preparations; Female; Fluphenazine; Humans; Male; Move | 1972 |
Are MAOI and other psychotropic drugs really compatible?
Topics: Adult; Amitriptyline; Barbiturates; Chlorpromazine; Drug Interactions; Humans; Male; Monoamine Oxida | 1972 |
The rabbit syndrome. A peculiar extrapyramidal reaction.
Topics: Aged; Anxiety; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Fatigue; Female; Humans; Male; M | 1972 |
Lack of indication for use of antiparkinson medication. A follow-up study.
Topics: Adolescent; Adult; Female; Follow-Up Studies; Humans; Intellectual Disability; Male; Mental Disorder | 1971 |
[On the use of sulpiride in psychiatric therapy].
Topics: Adolescent; Adult; Aged; Amitriptyline; Butyrophenones; Diazepam; Drug Synergism; Female; Humans; Ma | 1969 |
Action of L-Dopa in drug induced extrapyramidalism.
Topics: Adult; Chlorpromazine; Chronic Disease; Dihydroxyphenylalanine; Extrapyramidal Tracts; Female; Human | 1970 |
Greater than recommended drug dosages--some effects.
Topics: Adult; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Movement Disorders; Procyclidine; | 1970 |
A case of Capgras' syndrome.
Topics: Adult; Chlorpromazine; Delusions; Female; Humans; Psychotic Disorders; Schizophrenia; Trifluoperazin | 1970 |
The effect of akathisia on sleep. A preliminary study.
Topics: Adult; Eye Movements; Female; Humans; Middle Aged; Motor Activity; Phenothiazines; Schizophrenia; Sl | 1968 |
[Comparative effectiveness of various correctors of the neurologic side effects of neruoleptic drugs].
Topics: Humans; Paranoid Disorders; Parasympatholytics; Phenothiazines; Piperidines; Schizophrenia; Tranquil | 1968 |