trihexyphenidyl has been researched along with Cognition Disorders in 11 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated a patient with Parkinson's disease accompanied by intellectual impairment induced by long-term AC therapy." | 1.29 | Positron emission tomography of reversible intellectual impairment induced by long-term anticholinergic therapy. ( Momose, T; Nishiyama, K; Sakuta, M; Sugishita, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, Y | 1 |
| Zhao, Z | 1 |
| Wei, X | 1 |
| Zheng, Y | 1 |
| Yu, J | 1 |
| Zheng, J | 1 |
| Wang, L | 1 |
| Pomara, N | 2 |
| Sidtis, J | 1 |
| Belzer, K | 1 |
| Hernando, R | 1 |
| De La Pena, C | 1 |
| Sidtis, JJ | 1 |
| Lee, WK | 1 |
| Yu, ZH | 1 |
| Lee, CC | 1 |
| Kajimura, N | 1 |
| Mizuki, Y | 1 |
| Kai, S | 1 |
| Suetsugi, M | 1 |
| Yamada, M | 1 |
| Okuma, T | 1 |
| Nishiyama, K | 1 |
| Momose, T | 1 |
| Sugishita, M | 1 |
| Sakuta, M | 1 |
| Bédard, MA | 1 |
| Pillon, B | 1 |
| Dubois, B | 1 |
| Duchesne, N | 1 |
| Masson, H | 1 |
| Agid, Y | 1 |
| Ward, AG | 1 |
| Rawlins, MD | 1 |
| Schelosky, L | 1 |
| Benke, T | 1 |
| Poewe, WH | 1 |
| Parkes, JD | 1 |
| Baxter, RC | 1 |
| Marsden, CD | 1 |
| Rees, JE | 1 |
| Duvoisin, RC | 1 |
| Katz, R | 1 |
2 trials available for trihexyphenidyl and Cognition Disorders
| Article | Year |
|---|---|
Increased mental slowing associated with the APOE epsilon4 allele after trihexyphenidyl oral anticholinergic challenge in healthy elderly.
Topics: Administration, Oral; Aged; Alleles; Apolipoprotein E4; Awareness; Cholinergic Antagonists; Cognitio | 2008 |
Acute and long-term administration of anticholinergics in Parkinson's disease: specific effects on the subcortico-frontal syndrome.
Topics: Acute Disease; Cholinergic Antagonists; Cognition Disorders; Corpus Striatum; Cross-Over Studies; Do | 1999 |
9 other studies available for trihexyphenidyl and Cognition Disorders
| Article | Year |
|---|---|
Long-term trihexyphenidyl exposure alters neuroimmune response and inflammation in aging rat: relevance to age and Alzheimer's disease.
Topics: Aging; Animals; Antiparkinson Agents; Brain; Calcium-Binding Proteins; Cognition Disorders; Cytokine | 2016 |
Apolipoprotein E epsilon4 and anticholinergic cognitive toxicity.
Topics: Aged; Alleles; Apolipoprotein E4; Cardiovascular Diseases; Cholinergic Antagonists; Cognition Disord | 2009 |
Delayed neurological sequelae after carbon monoxide poisoning.
Topics: Adult; Antiparkinson Agents; Brain; Brain Infarction; Carbon Monoxide Poisoning; Cognition Disorders | 2008 |
Memory and cognitive impairments in a case of long-term trihexyphenidyl abuse.
Topics: Cognition Disorders; Electroencephalography; Humans; Male; Memory Disorders; Middle Aged; Psychologi | 1993 |
Positron emission tomography of reversible intellectual impairment induced by long-term anticholinergic therapy.
Topics: Aged; Antiparkinson Agents; Cognition Disorders; Humans; Male; Parkinson Disease; Time Factors; Tomo | 1995 |
Drug treatment in the elderly.
Topics: Aged; Cognition Disorders; Drug Interactions; Female; Humans; Nitrazepam; Pentazocine; Trihexyphenid | 1977 |
Effects of treatment with trihexyphenidyl on cognitive function in early Parkinson's disease.
Topics: Adult; Aged; Cognition Disorders; Female; Humans; Intelligence Tests; Male; Memory Disorders; Middle | 1991 |
Comparative trial of benzhexol, amantadine, and levodopa in the treatment of Parkinson's disease.
Topics: Aged; Amantadine; Cognition Disorders; Dihydroxyphenylalanine; Drug Therapy, Combination; Edema; Eye | 1974 |
Reversal of central anticholinergic syndrome in man by physostigmine.
Topics: Aged; Ataxia; Central Nervous System Diseases; Child; Cognition Disorders; Delirium; Female; Halluci | 1968 |