Page last updated: 2024-11-05

trihexyphenidyl and Chemical Dependence

trihexyphenidyl has been researched along with Chemical Dependence in 41 studies

Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.

Research Excerpts

ExcerptRelevanceReference
"Trihexyphenidyl (THP) is an anticholinergic drug misused to procure hallucination, sedation, and anxiolysis."1.48Misuse of Trihexyphenidyl (Artane) on Réunion Island. ( Ferré, JF; Hemery, P; Konareff, A; Lassalle, C; Scerra, S; Sherwin, K; Simon, N; Torrents, R, 2018)
"Trihexyphenidyl is a synthetic anticholinergic used in psychiatric patient for the relief of neuroleptic-induced extrapyramidal symptoms."1.29Trihexyphenidyl abuse in schizophrenic patient: a case report. ( Lo, Y; Tsai, SJ, 1996)
" In this study, 44 clinically stable schizophrenic inpatients were administered a battery of neuropsychological tests, and their performance was correlated with dosage of neuroleptic medication and benztropine."1.28Relationships between medication treatments and neuropsychological test performance in schizophrenia. ( Haas, GL; Hill, J; Keilp, JG; Sweeney, JA; Weiden, PJ, 1991)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199027 (65.85)18.7374
1990's8 (19.51)18.2507
2000's4 (9.76)29.6817
2010's2 (4.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Torrents, R1
Ferré, JF1
Konareff, A1
Hemery, P1
Sherwin, K1
Lassalle, C1
Simon, N1
Scerra, S1
Gowda, GS1
Singh, A1
Ravi, M1
Math, SB1
Hadidi, KA1
Nappo, SA1
de Oliveira, LG1
Sanchez, Zv1
Carlini, Ede A1
Schmutz, JL1
Barbaud, A1
Tréchot, P1
Kaminer, Y1
Munitz, H1
Wijsenbeek, H1
Pullen, GP1
Best, NR1
Maguire, J1
Crawshaw, JA1
Mullen, PE1
McInnis, M1
Petursson, H1
Izvol'skiĭ, SA1
Sofair, J1
Campion, J1
Angrist, B1
Mohan, D1
Mohandas, E2
Dube, S1
Craig, DH1
Rosen, P1
Smith, JM1
Harrison, G1
Kajimura, N1
Mizuki, Y1
Kai, S1
Suetsugi, M1
Yamada, M1
Okuma, T1
Lo, Y1
Tsai, SJ1
Zemishlany, Z1
Aizenberg, D1
Weiner, Z1
Weizman, A1
Buhrich, N1
Weller, A1
Kevans, P1
Goggin, DA1
Solomon, GF1
Zgirski, L1
Rubinstein, JS2
Weinstock, R1
Pakes, GE1
Macvicar, K1
Marriott, P1
Deutsch, A1
Eyma, J1
Sweeney, JA1
Keilp, JG1
Haas, GL1
Hill, J1
Weiden, PJ1
Palao, DJ1
Araúxo, A1
Bernardo, M1
Hidalgo, HA1
Mowers, RM1
Dieleman, BP1
van den Broek, WW1
van de Wetering, BJ1
Tandon, R1
Greden, J1
Fisch, RZ1
Kothari, VC1
Vanvaria, SK1
Mambwe, CC1
Haworth, A1
Appaya, MP1
Kisszékelyi, O1
Ott, B1
Jura, I1
Gayral, L1
Moron, P1
Escande, M1
Curie-Seimbres, P1
Dusek, K1
Janík, A1

Other Studies

41 other studies available for trihexyphenidyl and Chemical Dependence

ArticleYear
Misuse of Trihexyphenidyl (Artane) on Réunion Island.
    Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Age Factors; Cohort Studies; Female; Humans; Male; Middle Aged; Muscarinic Antago

2018
Mephentermine dependence syndrome - A new emerging trend of substance use.
    Asian journal of psychiatry, 2015, Volume: 17

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Humans; Male; Mephentermine; Muscarinic Antagonists; O

2015
Development of a screening method for the most commonly abused anticholinergic drugs in Jordan; trihexyphenidyl, procyclidine and biperiden.
    Legal medicine (Tokyo, Japan), 2004, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Biperiden; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Jorda

2004
Trihexyphenidyl (Artane): a Brazilian study of its abuse.
    Substance use & misuse, 2005, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Aged; Brazil; Child; Female; Hallucinogens; Humans; Male; Middle Aged; Muscarinic

2005
[Polymorphous bullous erythema and trihexiphenidyl (or why police questioning is not always the most productive method)].
    Annales de dermatologie et de venereologie, 2007, Volume: 134, Issue:11

    Topics: Adult; Antiparkinson Agents; Drug Eruptions; Erythema; Humans; Male; Skin Diseases, Vesiculobullous;

2007
Trihexyphenidyl (Artane) abuse: euphoriant and anxiolytic.
    The British journal of psychiatry : the journal of mental science, 1982, Volume: 140

    Topics: Adult; Anti-Anxiety Agents; Euphoria; Humans; Male; Substance-Related Disorders; Trihexyphenidyl

1982
Anticholinergic drug abuse: a common problem?
    British medical journal (Clinical research ed.), 1984, Sep-08, Volume: 289, Issue:6445

    Topics: Adult; Biperiden; Female; Humans; Male; Middle Aged; Orphenadrine; Parasympatholytics; Schizophrenia

1984
A study of benzhexol abuse.
    The British journal of psychiatry : the journal of mental science, 1984, Volume: 145

    Topics: Adolescent; Adult; Female; Hallucinations; Humans; Illusions; Male; Personality Disorders; Schizophr

1984
Trihexyphenidyl dependence.
    Acta psychiatrica Scandinavica, 1984, Volume: 69, Issue:6

    Topics: Adult; Anxiety; Female; Humans; Male; Parkinson Disease, Secondary; Substance Withdrawal Syndrome; S

1984
[Protracted psychoses in juvenile psychopath-like heboid schizophrenia (atypical variant of its course)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1983, Volume: 83, Issue:1

    Topics: Adolescent; Adult; Antisocial Personality Disorder; Female; Humans; Male; Opioid-Related Disorders;

1983
High dose trihexyphenidyl abuse with psychological dependence.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:4

    Topics: Adult; Dose-Response Relationship, Drug; Humans; Male; Substance-Related Disorders; Trihexyphenidyl

1983
Trihexyphenidyl abuse.
    British journal of addiction, 1981, Volume: 76, Issue:2

    Topics: Adult; Humans; Male; Substance-Related Disorders; Trihexyphenidyl

1981
Abuse of antiparkinsonian drugs.
    Annals of emergency medicine, 1981, Volume: 10, Issue:2

    Topics: Adult; Antiparkinson Agents; Benztropine; Female; Humans; Male; Physostigmine; Psychoses, Substance-

1981
Abuse of the antiparkinson drugs: a review of the literature.
    The Journal of clinical psychiatry, 1980, Volume: 41, Issue:10

    Topics: Antiparkinson Agents; Benztropine; Euphoria; Humans; Substance-Related Disorders; Trihexyphenidyl

1980
The abuse of anti-cholinergic drugs in adolescents.
    The British journal of psychiatry : the journal of mental science, 1980, Volume: 137

    Topics: Adult; Humans; Male; Substance-Related Disorders; Trihexyphenidyl

1980
Memory and cognitive impairments in a case of long-term trihexyphenidyl abuse.
    Pharmacopsychiatry, 1993, Volume: 26, Issue:2

    Topics: Cognition Disorders; Electroencephalography; Humans; Male; Memory Disorders; Middle Aged; Psychologi

1993
Trihexyphenidyl abuse in schizophrenic patient: a case report.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1996, Volume: 57, Issue:2

    Topics: Adult; Humans; Male; Parasympatholytics; Schizophrenia; Substance-Related Disorders; Trihexyphenidyl

1996
Trihexyphenidyl (Artane) abuse in schizophrenic patients.
    International clinical psychopharmacology, 1996, Volume: 11, Issue:3

    Topics: Adult; Antiparkinson Agents; Brief Psychiatric Rating Scale; Female; Hospitals, Psychiatric; Humans;

1996
Misuse of anticholinergic drugs by people with serious mental illness.
    Psychiatric services (Washington, D.C.), 2000, Volume: 51, Issue:7

    Topics: Adult; Benztropine; Female; Humans; Illicit Drugs; Male; Mental Disorders; Muscarinic Antagonists; N

2000
Trihexyphenidyl abuse for euphorigenic effect.
    The American journal of psychiatry, 1979, Volume: 136, Issue:4A

    Topics: Adult; Depression; Euphoria; Humans; Male; Substance-Related Disorders; Trihexyphenidyl

1979
Drug dependence and characteropathy.
    Bulletin of the Institute of Maritime and Tropical Medicine in Gdynia, 1979, Volume: 30, Issue:2

    Topics: Adult; Female; Humans; Hydrocarbons, Chlorinated; Male; Personality Disorders; Poland; Psychotropic

1979
Abuse of antiparkinsonism drugs. Feigning of extrapyramidal symptoms to obtain trihexyphenidyl.
    JAMA, 1978, Jun-02, Volume: 239, Issue:22

    Topics: Adult; Antiparkinson Agents; Basal Ganglia Diseases; Diagnosis, Differential; Female; Humans; Maling

1978
Interactive effects of trihexyphenidyl and coffee.
    The American journal of psychiatry, 1978, Volume: 135, Issue:5

    Topics: Caffeine; Coffee; Drug Synergism; Humans; Substance-Related Disorders; Trihexyphenidyl

1978
Abuse of anticholinergic drugs.
    The New England journal of medicine, 1978, Oct-12, Volume: 299, Issue:15

    Topics: Female; Humans; Parasympatholytics; Substance-Related Disorders; Trihexyphenidyl

1978
Abuse of trihexyphenidyl.
    JAMA, 1978, Nov-24, Volume: 240, Issue:22

    Topics: Humans; Substance-Related Disorders; Trihexyphenidyl; United States

1978
Abuse of antiparkinsonian drugs by psychiatric patients.
    The American journal of psychiatry, 1977, Volume: 134, Issue:7

    Topics: Adult; Antiparkinson Agents; Euphoria; Humans; Male; Mental Disorders; Psychoses, Substance-Induced;

1977
Trihexyphenidyl abuse.
    The American journal of psychiatry, 1977, Volume: 134, Issue:11

    Topics: Humans; Prisoners; Substance-Related Disorders; Trihexyphenidyl

1977
Letter: Dependence on antiparkinsonian drugs.
    British medical journal, 1976, Jan-17, Volume: 1, Issue:6002

    Topics: Antiparkinson Agents; Humans; Substance-Related Disorders; Trihexyphenidyl

1976
Massive ingestion of trihexyphenidyl.
    The American journal of psychiatry, 1992, Volume: 149, Issue:4

    Topics: Administration, Oral; Adult; Cerebral Palsy; Depressive Disorder; Drug Tolerance; Female; Humans; Se

1992
Relationships between medication treatments and neuropsychological test performance in schizophrenia.
    Psychiatry research, 1991, Volume: 37, Issue:3

    Topics: Adult; Antipsychotic Agents; Benztropine; Dose-Response Relationship, Drug; Drug Therapy, Combinatio

1991
[Hallucinosis due to trihexyphenidyl abuse].
    Medicina clinica, 1991, Jul-06, Volume: 97, Issue:6

    Topics: Adolescent; Female; Hallucinations; Humans; Substance-Related Disorders; Trihexyphenidyl

1991
Anticholinergic drug abuse.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:1

    Topics: Adult; Affect; Benztropine; Female; Humans; Male; Middle Aged; Parasympatholytics; Schizophrenia; Su

1990
[Abuse of anticholinergic agents].
    Nederlands tijdschrift voor geneeskunde, 1990, Mar-31, Volume: 134, Issue:13

    Topics: Adult; Humans; Male; Parasympatholytics; Psychophysiologic Disorders; Substance-Related Disorders; T

1990
Variety of effects of trihexyphenidyl (THP) on schizophrenic and non-schizophrenic abusers.
    Acta psychiatrica Scandinavica, 1987, Volume: 76, Issue:6

    Topics: Humans; Schizophrenia; Schizophrenic Psychology; Substance-Related Disorders; Trihexyphenidyl

1987
Trihexyphenidyl abuse: therapeutic implications for negative symptoms of schizophrenia?
    Acta psychiatrica Scandinavica, 1987, Volume: 75, Issue:1

    Topics: Adult; Borderline Personality Disorder; Dose-Response Relationship, Drug; Female; Hallucinations; Hu

1987
Trihexyphenidyl abuse.
    East African medical journal, 1987, Volume: 64, Issue:2

    Topics: Adult; Drug Prescriptions; Humans; Male; Substance-Related Disorders; Trihexyphenidyl

1987
Trihexyphenidyl dependence.
    The Journal of the Association of Physicians of India, 1985, Volume: 33, Issue:12

    Topics: Adult; Humans; Male; Substance-Related Disorders; Trihexyphenidyl

1985
[Antiparkinsonism drug (Parkan) as a hallucinogen].
    Orvosi hetilap, 1973, Apr-15, Volume: 114, Issue:15

    Topics: Adolescent; Hallucinogens; Humans; Hungary; Legislation, Drug; Substance-Related Disorders; Trihexyp

1973
[Artane--a narcotic drug?].
    Der Nervenarzt, 1972, Volume: 43, Issue:4

    Topics: Adolescent; Female; Hallucinations; Hallucinogens; Humans; Psychomotor Disorders; Substance-Related

1972
[Can we speak of trihexyphenidyl toxicomania?].
    Annales medico-psychologiques, 1971, Volume: 2, Issue:3

    Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Substance-Related Disorders; Trihexyphenidyl

1971
[Forms of dependency on psychopharmaceutic drugs and sleep disorders].
    Activitas nervosa superior, 1968, Volume: 10, Issue:2

    Topics: Humans; Mental Disorders; Sleep Wake Disorders; Substance Withdrawal Syndrome; Substance-Related Dis

1968