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trihexyphenidyl and Cervical Dystonia

trihexyphenidyl has been researched along with Cervical Dystonia in 20 studies

Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.

Cervical Dystonia: A common form of DYSTONIA due to involuntary sustained or spasmodic, repetitive muscle contractions in the neck region. According to the position of the twisted neck and head, cervical dystonia can be categorized as torticollis, laterocollis, retrocollis, and a combination of these abnormal postures.

Research Excerpts

ExcerptRelevanceReference
"An electromyographic method was used to study the effect of combination therapy with L-dopa and trihexyphenidyl on tremor in thirty patients suffering from extrapyramidal motor system disease."7.66Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor. ( Hökendorf, H, 1979)
"A total of 15 patients affected by idiopathic dystonia (7 with generalized and 8 with focal or segmental dystonia) were subjected to therapy with bromocriptine at low doses, pimozide and trihexyphenidyl."3.66Idiopathic dystonia: neuropharmacological study. ( Angelini, L; Broggi, G; Caraceni, T; Giovannini, P; Girotti, F; Nardocci, N; Scigliano, G, 1982)
"An electromyographic method was used to study the effect of combination therapy with L-dopa and trihexyphenidyl on tremor in thirty patients suffering from extrapyramidal motor system disease."3.66Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor. ( Hökendorf, H, 1979)
"A total of 105 patients with cervical dystonia were selected and randomly divided into medication treatment group (A group), botulinum toxin treatment group under the guidance of ultrasound treatment (B group) and botulinum toxin under the guidance of ultrasound treatment combined with orthopedic joint brace treatment group (C group)."2.80Efficacy analysis of ultrasound-guided local injection of botulinum toxin type A treatment with orthopedic joint brace in patients with cervical dystonia. ( Chen, HX; Ding, XD; Huang, L; Wang, H; Wang, W; Xiao, HQ, 2015)
" We found no information on a dose-response relationship with BtA, differences between BtA formulations or different anticholinergics, the utility of electromyography-guided injections, or the duration of treatment effect."2.72Botulinum toxin type A versus anticholinergics for cervical dystonia. ( Castelão, M; Costa, J; Duarte, GS; Ferreira, J; Marques, RE; Moore, AP; Rodrigues, FB; Sampaio, C, 2021)
" Oral administration of high dosage of anticholinergic drugs is firstly recommended for the treatment of dystonia."2.41[Medical treatment of dystonia]. ( Kachi, T, 2001)
"Spasmodic torticollis is classified as a focal dystonia."2.38[Therapeutic possibilities in spasmodic torticollis]. ( Auff, E; Deecke, L; Wöber, C, 1991)
"To determine whether patients with cervical dystonia have electrophysiological signs of disinhibition in the somatosensory cortex by recording high-frequency oscillations (HFOs) in somatosensory evoked potentials (SEPs)."1.32Disinhibition of the somatosensory cortex in cervical dystonia-decreased amplitudes of high-frequency oscillations. ( Hashimoto, I; Inoue, K; Kawakami, H; Matsumoto, M; Mimori, Y; Miyachi, T; Shirai, T, 2004)
"Three patients who had adult-onset dystonia and who were exhibiting respiratory problems were examined clinically and electrophysiologically."1.29Involvement of respiratory muscles in adult-onset dystonia: a clinical and electrophysiological study. ( Bergouignan, FX; Burbaud, P; Ferrer, X; Julien, J; Lagueny, A; Le Masson, G, 1995)
"Clonic torticollis were less frequently associated to pain."1.28[Craniocervical dystonia and facial hemispasm: clinical and pharmacological characteristics of 52 patients]. ( Astarloa, R; de Yébenes, JG; Morales, B; Peñafiel, N; Rábano, J, 1991)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19908 (40.00)18.7374
1990's3 (15.00)18.2507
2000's5 (25.00)29.6817
2010's3 (15.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Rodrigues, FB1
Duarte, GS1
Castelão, M1
Marques, RE1
Ferreira, J1
Sampaio, C1
Moore, AP1
Costa, J1
Burciu, RG1
Hess, CW1
Coombes, SA1
Ofori, E1
Shukla, P1
Chung, JW1
McFarland, NR1
Wagle Shukla, A1
Okun, MS1
Vaillancourt, DE1
Huang, L1
Chen, HX1
Ding, XD1
Xiao, HQ1
Wang, W1
Wang, H1
Patel, S1
Martino, D1
Kachi, T1
Inoue, K1
Hashimoto, I1
Shirai, T1
Kawakami, H1
Miyachi, T1
Mimori, Y1
Matsumoto, M1
Tey, HL1
Seet, RC1
Lim, EC1
Desarkar, P1
Thakur, A1
Sinha, VK1
Girotti, F1
Scigliano, G1
Nardocci, N1
Angelini, L1
Broggi, G1
Giovannini, P1
Caraceni, T1
Marsden, CD1
Marion, MH1
Quinn, N1
Lagueny, A1
Burbaud, P1
Le Masson, G1
Bergouignan, FX1
Ferrer, X1
Julien, J1
DiMario, FJ1
Hökendorf, H1
Astarloa, R1
Morales, B1
Peñafiel, N1
Rábano, J1
de Yébenes, JG1
Wöber, C1
Auff, E1
Deecke, L1
Trend, P1
Trimble, M1
Wessely, S1
Besson, JA1
Ebmeier, KP1
Gemmell, HG1
Sharp, PF1
McFadyen, M1
Smith, FW1
Boyson, SJ1
Scherokman, B1
Jabbari, B1
Gunderson, CH1
Miller, JM1
Rappaport, HL1
Wolf, SM1

Reviews

4 reviews available for trihexyphenidyl and Cervical Dystonia

ArticleYear
Botulinum toxin type A versus anticholinergics for cervical dystonia.
    The Cochrane database of systematic reviews, 2021, 04-14, Volume: 4

    Topics: Botulinum Toxins, Type A; Humans; Muscarinic Antagonists; Neuromuscular Agents; Torticollis; Trihexy

2021
Cervical dystonia: from pathophysiology to pharmacotherapy.
    Behavioural neurology, 2013, Volume: 26, Issue:4

    Topics: Botulinum Toxins; Botulinum Toxins, Type A; Humans; Muscarinic Antagonists; Neuromuscular Agents; To

2013
[Medical treatment of dystonia].
    Rinsho shinkeigaku = Clinical neurology, 2001, Volume: 41, Issue:12

    Topics: Cholinergic Antagonists; Clonazepam; Diazepam; Dopamine Antagonists; Dystonia; Humans; Levodopa; Tor

2001
[Therapeutic possibilities in spasmodic torticollis].
    Wiener klinische Wochenschrift, 1991, Volume: 103, Issue:1

    Topics: Accessory Nerve; Biofeedback, Psychology; Botulinum Toxins; Humans; Spinal Nerve Roots; Torticollis;

1991

Trials

2 trials available for trihexyphenidyl and Cervical Dystonia

ArticleYear
Efficacy analysis of ultrasound-guided local injection of botulinum toxin type A treatment with orthopedic joint brace in patients with cervical dystonia.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:11

    Topics: Administration, Oral; Adult; Baclofen; Botulinum Toxins, Type A; Braces; Carbamazepine; Cross-Sectio

2015
Trihexyphenidyl and torticollis.
    Neurology, 1986, Volume: 36, Issue:12

    Topics: Adult; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Male; Middle Aged; To

1986

Other Studies

14 other studies available for trihexyphenidyl and Cervical Dystonia

ArticleYear
Functional activity of the sensorimotor cortex and cerebellum relates to cervical dystonia symptoms.
    Human brain mapping, 2017, Volume: 38, Issue:9

    Topics: Anti-Dyskinesia Agents; Botulinum Toxins; Brain Mapping; Cerebellum; Cohort Studies; Female; Humans;

2017
Disinhibition of the somatosensory cortex in cervical dystonia-decreased amplitudes of high-frequency oscillations.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2004, Volume: 115, Issue:7

    Topics: Adult; Aged; Case-Control Studies; Dominance, Cerebral; Evoked Potentials, Somatosensory; Female; Hu

2004
Tuberculomas causing cervical dystonia.
    Internal medicine journal, 2005, Volume: 35, Issue:4

    Topics: Adult; Antiparkinson Agents; Antitubercular Agents; Humans; Magnetic Resonance Imaging; Male; Tortic

2005
Aripiprazole-induced acute dystonia.
    The American journal of psychiatry, 2006, Volume: 163, Issue:6

    Topics: Acute Disease; Adolescent; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Dystonia; Humans; M

2006
Idiopathic dystonia: neuropharmacological study.
    Journal of neurology, 1982, Volume: 227, Issue:4

    Topics: Adolescent; Adult; Aged; Bromocriptine; Dystonia; Female; Humans; Male; Middle Aged; Pimozide; Syndr

1982
The treatment of severe dystonia in children and adults.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:11

    Topics: Adolescent; Adult; Age Factors; Child; Drug Therapy, Combination; Dystonia Musculorum Deformans; Fem

1984
Involvement of respiratory muscles in adult-onset dystonia: a clinical and electrophysiological study.
    Movement disorders : official journal of the Movement Disorder Society, 1995, Volume: 10, Issue:6

    Topics: Administration, Oral; Aged; Baclofen; Botulinum Toxins; Delayed-Action Preparations; Diaphragm; Dyst

1995
Childhood head tremor.
    Journal of child neurology, 2000, Volume: 15, Issue:1

    Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Male;

2000
Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor.
    The Journal of international medical research, 1979, Volume: 7, Issue:1

    Topics: Aged; Basal Ganglia Diseases; Drug Therapy, Combination; Electromyography; Female; Humans; Levodopa;

1979
[Craniocervical dystonia and facial hemispasm: clinical and pharmacological characteristics of 52 patients].
    Revista clinica espanola, 1991, Volume: 189, Issue:7

    Topics: Adolescent; Adult; Aged; Blepharospasm; Clonazepam; Facial Nerve Diseases; Female; Humans; Male; Mid

1991
Schizophrenic psychosis associated with benzhexol (artane) therapy.
    Journal of neurology, neurosurgery, and psychiatry, 1989, Volume: 52, Issue:9

    Topics: Adult; Female; Humans; Schizophrenia; Torticollis; Trihexyphenidyl

1989
Brain imaging and treatment response in spasmodic torticollis.
    The British journal of psychiatry : the journal of mental science, 1988, Volume: 153

    Topics: Adult; Brain; Humans; Male; Spasm; Tomography, Emission-Computed; Torticollis; Trihexyphenidyl

1988
Bethanechol for anticholinergic side effects.
    Annals of neurology, 1988, Volume: 23, Issue:4

    Topics: Adult; Bethanechol Compounds; Female; Humans; Torticollis; Trihexyphenidyl

1988
Reserpine: cause and treatment of oral-facial dyskinesia.
    Bulletin of the Los Angeles neurological societies, 1973, Volume: 38, Issue:2

    Topics: Deglutition Disorders; Diazepam; Face; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged

1973