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trihexyphenidyl and Basal Ganglia Diseases

trihexyphenidyl has been researched along with Basal Ganglia Diseases in 35 studies

Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.

Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"An electromyographic method was used to study the effect of combination therapy with L-dopa and trihexyphenidyl on tremor in thirty patients suffering from extrapyramidal motor system disease."7.66Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor. ( Hökendorf, H, 1979)
"An electromyographic method was used to study the effect of combination therapy with L-dopa and trihexyphenidyl on tremor in thirty patients suffering from extrapyramidal motor system disease."3.66Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor. ( Hökendorf, H, 1979)
"Acute withdrawal is therefore unjustified, but occasional revision of dosage of anti-Parkinsonian drugs is advisable."2.64Benzhexol and side effects with long-acting fluphenazine therapy. ( Crammer, JL; Grove, L, 1972)
" Though both blepharospasm and OMD are thought to represent focal dystonia at different body sites, the extent of improvement achieved with these drugs at the dosage employed differed markedly."1.27Meige's syndrome: acute and chronic responses to clonazepan and anticholinergics. ( Giménez-Roldán, S; Hípola, D; Mateo, D, 1984)
"In older patients hemidystonia appeared within 6 months after injury."1.27Hemidystonia: a report of 22 patients and a review of the literature. ( Jankovic, J; Pettigrew, LC, 1985)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199031 (88.57)18.7374
1990's1 (2.86)18.2507
2000's2 (5.71)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aravind, VK1
Krishnaram, VD1
Neethiarau, V1
Srinivasan, KG1
Verma, R1
Lalla, R1
Patil, TB1
MULLER, L1
ANDERSSON, B1
KUVER, G1
GOEBEL, U1
Grosse, P1
Edwards, M1
Tijssen, MAJ1
Schrag, A1
Lees, AJ1
Bhatia, KP1
Brown, P1
Manos, N1
Gkiouzepas, J1
Ungvári, G1
Bitter, I1
Czobor, P1
Vitrai, J1
Pethö, B1
Stoudemire, A1
Luther, JS1
Irwin, GE1
Simon, JE1
Hípola, D2
Mateo, D2
Giménez-Roldán, S2
Duvoisin, RC1
Daniel, AE1
Chapel, JL1
Schwartz, M1
Weller, B1
Erdreich, M1
Sharf, B1
Allain, H1
Bentue-Ferrer, D1
Brissot, R1
Morisot, D1
Madigand, M1
Menault, F1
Hökendorf, H1
Rubinstein, JS1
Jellinek, T1
Alpert, M1
Diamond, F1
Laski, EM1
Yosselson, S1
Kaplan, A1
Stimmel, GL1
McEvoy, JP1
Hitri, A1
Craft, RB1
Sethi, R1
Sinha, D1
Orbe, M1
Muñoz-Blanco, JL1
Faulstich, ME1
Carnrike, CL1
Williamson, DA1
McInnis, M1
Petursson, H1
Pettigrew, LC1
Jankovic, J1
Shintomi, K1
Yamamura, M1
Chase, TN1
Black, D1
Woollacott, S1
Grove, L1
Crammer, JL1
Klett, CJ1
Caffey, E1
Dreyfuss, J1
Beer, B1
Devine, DD1
Roberts, BF1
Schreiber, EC1
Bastecký, J1
Vinar, O1
Taussigová, D1
Villeneuve, A1

Reviews

2 reviews available for trihexyphenidyl and Basal Ganglia Diseases

ArticleYear
Blepharospasm and Meige syndrome: a review of diagnostic, aetiological and treatment approaches.
    Journal of psychosomatic research, 1985, Volume: 29, Issue:1

    Topics: Acetylcholine; Basal Ganglia; Basal Ganglia Diseases; Behavior Therapy; Biofeedback, Psychology; Ble

1985
Drug-induced extrapyramidal disorders.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Benztropine; Dihydroxyphenylalanine; Dopa

1972

Trials

5 trials available for trihexyphenidyl and Basal Ganglia Diseases

ArticleYear
Discontinuing antiparkinson medication in chronic schizophrenics. At what cost to the patient?
    Acta psychiatrica Scandinavica, 1981, Volume: 63, Issue:1

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chronic Disease; Clinical Trials as Topic; Double-Blin

1981
A double-blind crossover comparison of antiparkinson drug therapy: amantadine versus anticholinergics in 90 normal volunteers, with an emphasis on differential effects on memory function.
    The Journal of clinical psychiatry, 1987, Volume: 48 Suppl

    Topics: Adult; Age Factors; Aged; Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Cli

1987
Withdrawal of trihexyphenidyl.
    Acta psychiatrica Scandinavica, 1985, Volume: 71, Issue:3

    Topics: Adult; Anxiety; Basal Ganglia Diseases; Double-Blind Method; Female; Humans; Male; Middle Aged; Psyc

1985
Benzhexol and side effects with long-acting fluphenazine therapy.
    British medical journal, 1972, Jan-29, Volume: 1, Issue:5795

    Topics: Administration, Oral; Adult; Aged; Basal Ganglia Diseases; Clinical Trials as Topic; Female; Fluphen

1972
Evaluating the long-term need for antiparkinson drugs by chronic schizophrenics.
    Archives of general psychiatry, 1972, Volume: 26, Issue:4

    Topics: 1-Propanol; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Benztropine; Biperiden; Chronic Dis

1972

Other Studies

28 other studies available for trihexyphenidyl and Basal Ganglia Diseases

ArticleYear
Wilson's disease--a rare psychiatric presentation.
    Journal of the Indian Medical Association, 2009, Volume: 107, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Adult; Basal Ganglia Diseases; Diagnosis, Differential; Hepatolenticul

2009
Is blinking of the eyes affected in extrapyramidal disorders? An interesting observation in a patient with Wilson disease.
    BMJ case reports, 2012, Nov-27, Volume: 2012

    Topics: Adult; Antiparkinson Agents; Basal Ganglia Diseases; Blinking; Carbidopa; Ceruloplasmin; Drug Therap

2012
[Mental disorders as complication of pargitan therapy of extrapyramidal symptoms].
    Svenska lakartidningen, 1953, May-15, Volume: 50, Issue:20

    Topics: Basal Ganglia Diseases; Humans; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders;

1953
[Comparative research on new drugs for the treatment of extrapyramidal motor disorders].
    Die Medizinische, 1955, Oct-15, Issue:42

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Disease; Extrapyramidal Tracts; Humans; Muscle Relaxan

1955
[Clinical results with artane in parkinsonism and other extrapyramidal syndromes].
    Munchener medizinische Wochenschrift (1950), 1951, May-25, Volume: 93, Issue:21

    Topics: Basal Ganglia Diseases; Extrapyramidal Tracts; Parkinsonian Disorders; Syndrome; Trihexyphenidyl

1951
Patterns of EMG-EMG coherence in limb dystonia.
    Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:7

    Topics: Adult; Anterior Compartment Syndrome; Anti-Dyskinesia Agents; Anticonvulsants; Antiparkinson Agents;

2004
[The role of high-dosage neuroleptic therapy and electroshock in the treatment of the acute phase of schizophrenia].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1981, Volume: 33, Issue:8

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Dose-Response Relationship, Drug; Electroconvul

1981
Neuroleptic malignant syndrome and neuroleptic-induced catatonia: differential diagnosis and treatment.
    International journal of psychiatry in medicine, 1984, Volume: 14, Issue:1

    Topics: Aged; Antipsychotic Agents; Basal Ganglia Diseases; Carbidopa; Catatonia; Diagnosis, Differential; F

1984
Neuroleptic malignant syndrome.
    The Journal of emergency medicine, 1984, Volume: 1, Issue:3

    Topics: Basal Ganglia Diseases; Chronic Disease; Diagnosis, Differential; Dibenzoxazepines; Dose-Response Re

1984
Meige's syndrome: acute and chronic responses to clonazepan and anticholinergics.
    European neurology, 1984, Volume: 23, Issue:6

    Topics: Aged; Basal Ganglia Diseases; Benzodiazepinones; Clonazepam; Dystonia; Female; Follow-Up Studies; Hu

1984
Meige syndrome: relief on high-dose anticholinergic therapy.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:1

    Topics: Ambenonium Chloride; Basal Ganglia Diseases; Benztropine; Carbidopa; Humans; Parasympatholytics; Tri

1983
Tics of Tourette: important points in management.
    Journal of developmental and behavioral pediatrics : JDBP, 1981, Volume: 2, Issue:4

    Topics: Basal Ganglia Diseases; Child; Child, Preschool; Female; Haloperidol; Humans; Male; Tourette Syndrom

1981
Rabbit syndrome and tardive dyskinesia: two complications of chronic neuroleptic treatment.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:5

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Diagnosis, Differential; Dyskinesia, Drug-Induced; Fem

1995
[Shy and Drager syndrome. Physiopathological and pharmacological approach based upon one case (author's transl)].
    La Nouvelle presse medicale, 1979, Sep-10, Volume: 8, Issue:34

    Topics: Basal Ganglia Diseases; Dibenzazepines; Drug Therapy, Combination; Humans; Hypotension, Orthostatic;

1979
Combination therapy of extrapyramidal disease with trihexyphenidyl and L-dopa: an electromyographic study with specific reference to tremor.
    The Journal of international medical research, 1979, Volume: 7, Issue:1

    Topics: Aged; Basal Ganglia Diseases; Drug Therapy, Combination; Electromyography; Female; Humans; Levodopa;

1979
Abuse of antiparkinsonism drugs. Feigning of extrapyramidal symptoms to obtain trihexyphenidyl.
    JAMA, 1978, Jun-02, Volume: 239, Issue:22

    Topics: Adult; Antiparkinson Agents; Basal Ganglia Diseases; Diagnosis, Differential; Female; Humans; Maling

1978
Mood elevating effect of trihexyphenidyl and biperiden in individuals taking antipsychotic medication.
    Diseases of the nervous system, 1977, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Biperiden; Emotions; Euphoria; Fema

1977
Anticholinergic exacerbation of phenothiazine-induced extrapyramidal syndrome.
    The American journal of psychiatry, 1976, Volume: 133, Issue:9

    Topics: Adult; Basal Ganglia Diseases; Chlorpromazine; Humans; Substance Withdrawal Syndrome; Trifluoperazin

1976
Letter: Neurotoxic reaction to haloperidol in a thyrotoxic patient.
    The New England journal of medicine, 1975, Jul-24, Volume: 293, Issue:4

    Topics: Adult; Basal Ganglia Diseases; Diphenhydramine; Female; Haloperidol; Humans; Hyperthyroidism; Trihex

1975
Neuroleptics and the corpus striatum: clinical implications.
    Diseases of the nervous system, 1976, Volume: 37, Issue:4

    Topics: Acetylcholine; Basal Ganglia Diseases; Benztropine; Corpus Striatum; Dopamine; Fluphenazine; Haloper

1976
Drug levels and antiparkinsonian drugs in neuroleptic-treated schizophrenic patients.
    Clinical neuropharmacology, 1987, Volume: 10, Issue:3

    Topics: Adult; Amantadine; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Benztropine;

1987
Acute pharmacologic tests in cranial dystonia.
    Advances in neurology, 1988, Volume: 49

    Topics: Adult; Aged; Basal Ganglia Diseases; Clonazepam; Diagnosis, Differential; Double-Blind Method; Femal

1988
Hemidystonia: a report of 22 patients and a review of the literature.
    Journal of neurology, neurosurgery, and psychiatry, 1985, Volume: 48, Issue:7

    Topics: Adolescent; Adult; Aged; Basal Ganglia Diseases; Brain Damage, Chronic; Brain Diseases; Brain Injuri

1985
Letter: Effects of antiparkinsonian drugs on neuroleptic-induced extrapyramidal signs in monkeys.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:8

    Topics: Animals; Antiparkinson Agents; Basal Ganglia Diseases; Benztropine; Glycolates; Haloperidol; Haplorh

1973
Acute toxic psychosis in two children treated with benzhexol hydrochloride (Artane).
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 125

    Topics: Adolescent; Basal Ganglia Diseases; Child, Preschool; Female; Humans; Hyperkinesis; Psychoses, Subst

1974
Fluphenazine-induced parkinsonism in the baboon: pharmacological and metabolic studies.
    Neuropharmacology, 1972, Volume: 11, Issue:2

    Topics: Animals; Basal Ganglia Diseases; Benztropine; Carbon Isotopes; Chromatography, Thin Layer; Feces; Fe

1972
Extrapyramidal symptoms in the course of fluphenazine treatment.
    Activitas nervosa superior, 1972, Volume: 14, Issue:2

    Topics: Adult; Basal Ganglia Diseases; Delayed-Action Preparations; Female; Fluphenazine; Humans; Male; Move

1972
The rabbit syndrome. A peculiar extrapyramidal reaction.
    Canadian Psychiatric Association journal, 1972, Volume: 17, Issue:2

    Topics: Aged; Anxiety; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Fatigue; Female; Humans; Male; M

1972