trihexyphenidyl has been researched along with Atherosclerotic Parkinsonism in 38 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind study was carried out on the therapeutic effects of dexetimide and artane in the control of neuroleptic-induced extrapyramidal side-effects in 261 cases of schizophrenia." | 5.07 | [A double-blind study on the effect of dexetimide in the control of neuroleptic-induced extrapyramidal side-effects]. ( Chen, Y, 1991) |
| "Amantadine is a putative dopaminergic compound known to be therapeutically effective in idiopathic and postencephalitic Parkinson's disease." | 2.64 | Amantadine versus trihexyphenidyl in the treatment of neuroleptic-induced parkinsonism. ( Fann, WE; Lake, CR, 1976) |
| "Trihexyphenidyl was then studied in combination with the selective dopamine receptor D1 agonist SKF-82958 [(+/-)-6-chloro-7-8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro- 1H-benzazepine hydrobromide] and the selective D2 agonist N-0923 [(-)2-(N-propyl-N-2-thienylethyl)amino-5-hydroxytetralin HCl] on rotational behavior in five 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned hemiparkinsonian monkeys." | 1.30 | Trihexyphenidyl interactions with the dopamine D1-selective receptor agonist SKF-82958 and the D2-selective receptor agonist N-0923 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced hemiparkinsonian monkeys. ( Domino, EF; Ni, L, 1998) |
| " After chronic haloperidol dosing (vehicle, 0." | 1.30 | Chronic haloperidol produces a time- and dose-related slowing of lick rhythm in rats: implications for rodent models of tardive dyskinesia and neuroleptic-induced parkinsonism. ( Fowler, SC; Wang, G, 1998) |
| " Both studies yielded significant correlations between memory impairment and dosage levels of benzhexol." | 1.27 | The adverse effect of benzhexol on memory in Parkinson's disease. ( Berrios, GE; Miller, E; Politynska, B, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (73.68) | 18.7374 |
| 1990's | 7 (18.42) | 18.2507 |
| 2000's | 3 (7.89) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bata-García, JL | 1 |
| Villanueva-Toledo, J | 1 |
| Gutiérrez-Ospina, G | 1 |
| Alvarez-Cervera, FJ | 1 |
| Heredia-López, FJ | 1 |
| Góngora-Alfaro, JL | 1 |
| Panagariya, A | 1 |
| Sharma, B | 1 |
| Dev, A | 1 |
| Lee, WK | 1 |
| Yu, ZH | 1 |
| Lee, CC | 1 |
| McInnis, M | 1 |
| Petursson, H | 1 |
| Magnus, RV | 1 |
| Ondo, WG | 1 |
| Hurwitz, BJ | 1 |
| Picard, F | 1 |
| de Saint-Martin, A | 1 |
| Salmon, E | 1 |
| Hirsch, E | 1 |
| Marescaux, C | 1 |
| Domino, EF | 2 |
| Ni, L | 2 |
| Fowler, SC | 1 |
| Wang, G | 1 |
| Kolakowska, T | 1 |
| Wiles, DH | 1 |
| Gelder, MG | 1 |
| McNeilly, AS | 1 |
| Matthews, RT | 1 |
| Chiou, CY | 1 |
| Davis, KL | 1 |
| Yesavage, JA | 1 |
| Berger, PA | 1 |
| Agnoli, A | 1 |
| Ruggieri, S | 1 |
| Denaro, A | 1 |
| Lelli, A | 1 |
| Fann, WE | 1 |
| Lake, CR | 1 |
| Crow, TJ | 1 |
| Johnstone, EC | 1 |
| McClelleand, HA | 1 |
| Evtushenko, SK | 1 |
| Chen, Y | 1 |
| Kryzhanovskiĭ, GN | 3 |
| Shandra, AA | 2 |
| Godlevskiĭ, LS | 2 |
| Mikhaleva, II | 1 |
| Wirshing, WC | 1 |
| Freidenberg, DL | 1 |
| Cummings, JL | 1 |
| Bartzokis, G | 1 |
| Atadzhanov, MA | 1 |
| Voronina, TA | 1 |
| Nerobkova, LN | 1 |
| Vågen, R | 1 |
| Götestam, KG | 1 |
| Fayen, M | 1 |
| Goldman, MB | 1 |
| Moulthrop, MA | 1 |
| Luchins, DJ | 1 |
| Hardie, RJ | 1 |
| Lees, AJ | 1 |
| Saitoh, T | 1 |
| Makul'kin, RF | 1 |
| Rozhkov, VS | 1 |
| Miller, E | 1 |
| Berrios, GE | 1 |
| Politynska, B | 1 |
| Carotti, A | 1 |
| Tomassetti, G | 1 |
| Lucciarini, L | 1 |
| Barone, G | 1 |
| Mugnai, A | 1 |
| Klawans, HL | 1 |
| Bordeleau, JM | 1 |
| Tétreault, L | 1 |
| Dreyfuss, J | 1 |
| Beer, B | 1 |
| Devine, DD | 1 |
| Roberts, BF | 1 |
| Schreiber, EC | 1 |
| Freeman, H | 1 |
| Mehta, IS | 1 |
| Pecknold, JC | 1 |
| Ananth, JV | 1 |
| Ban, TA | 1 |
| Lehmann, HE | 1 |
| Ridges, AP | 1 |
| Harper, P | 1 |
| Gjerris, F | 1 |
| Maller, O | 1 |
| Heller, S | 1 |
| Dandiya, PC | 1 |
| Bhargava, LP | 1 |
| Grabowski, K | 1 |
1 review available for trihexyphenidyl and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
The pharmacology of parkinsonism (a review).
Topics: Acetylcholine; Animals; Atropa belladonna; Atropine; Central Nervous System; Chlorpromazine; Dextroa | 1968 |
9 trials available for trihexyphenidyl and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
A comparison of biperiden hydrochloride (Akineton) and benzhexol (Artane) in the treatment of drug-induced Parkinsonism.
Topics: Adolescent; Adult; Biperiden; Female; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Piper | 1980 |
Clinical significance of plasma chlorpromazine levels. II. Plasma levels of the drug, some of its metabolites and prolactin in patients receiving long-term phenothiazine treatment.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Drug Tolerance; Female; Humans; Male; Middle Aged; Park | 1976 |
Amantadine versus trihexyphenidyl in the treatment of neuroleptic-induced parkinsonism.
Topics: Amantadine; Clinical Trials as Topic; Humans; Parkinson Disease, Secondary; Tranquilizing Agents; Tr | 1976 |
[A double-blind study on the effect of dexetimide in the control of neuroleptic-induced extrapyramidal side-effects].
Topics: Adolescent; Adult; Antipsychotic Agents; Dexetimide; Double-Blind Method; Female; Humans; Male; Midd | 1991 |
Effects of anticholinergic agents on patients with tardive dyskinesia and concomitant drug-induced parkinsonism.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; Human | 1989 |
An experimental evaluation of the euphoric properties of antiparkinson drugs on psychotic patients.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Double-Blind Method; Euphoria; Female; Humans; Male; | 1986 |
Differential memory function with dopaminergic versus anticholinergic treatment of drug-induced extrapyramidal symptoms.
Topics: Adult; Amantadine; Antipsychotic Agents; Cerebral Ventricles; Clinical Trials as Topic; Dilatation, | 1988 |
A double-blind comparison of the efficacy of EX 10-029 and trihexyphenidyl hydrochloride in relieving drug-induced Parkinsonian symptoms.
Topics: Antiparkinson Agents; Clinical Trials as Topic; Female; Humans; Male; Methods; Middle Aged; Parkinso | 1972 |
Neutralization of extrapyramidal side-effects with Methixene.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Extrapyramidal Tracts; Female; Humans; Male; Middle Age | 1971 |
28 other studies available for trihexyphenidyl and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
Sustained improvement of motor function in hemiparkinsonian rats chronically treated with low doses of caffeine or trihexyphenidyl.
Topics: Animals; Antiparkinson Agents; Brain; Caffeine; Central Nervous System Stimulants; Dose-Response Rel | 2007 |
Pallido-pyramidal syndrome: a rare entity.
Topics: Adult; Antiparkinson Agents; Globus Pallidus; Humans; Male; Parkinson Disease, Secondary; Pyramidal | 2007 |
Delayed neurological sequelae after carbon monoxide poisoning.
Topics: Adult; Antiparkinson Agents; Brain; Brain Infarction; Carbon Monoxide Poisoning; Cognition Disorders | 2008 |
Trihexyphenidyl dependence.
Topics: Adult; Anxiety; Female; Humans; Male; Parkinson Disease, Secondary; Substance Withdrawal Syndrome; S | 1984 |
Tardive dyskinesia and pseudo-parkinsonism. In a nursing home patient who itched.
Topics: Aged; Clonazepam; Dyskinesia, Drug-Induced; Extrapyramidal Tracts; Female; Humans; Parkinson Disease | 1993 |
Postencephalitic stereotyped involuntary movements responsive to L-Dopa.
Topics: Adult; Bromocriptine; Dopamine Agonists; Drug Therapy, Combination; Encephalitis; Humans; Levodopa; | 1996 |
Trihexyphenidyl interactions with the dopamine D1-selective receptor agonist SKF-82958 and the D2-selective receptor agonist N-0923 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced hemiparkinsonian monkeys.
Topics: Animals; Antiparkinson Agents; Benzazepines; Dopamine Agonists; Dose-Response Relationship, Drug; Dr | 1998 |
Chronic haloperidol produces a time- and dose-related slowing of lick rhythm in rats: implications for rodent models of tardive dyskinesia and neuroleptic-induced parkinsonism.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, | 1998 |
Trihexyphenidyl potentiation of L-DOPA: reduced effectiveness three years later in MPTP-induced chronic hemiparkinsonian monkeys.
Topics: Animals; Antiparkinson Agents; Chronic Disease; Dopamine Agents; Dose-Response Relationship, Drug; D | 1998 |
Effects of diethylcholine in two animal models of Parkinsonism tremors.
Topics: Animals; Brain Chemistry; Carbachol; Choline; Disease Models, Animal; Male; Mice; Parkinson Disease, | 1979 |
Single case study. Possible organophosphate-induced parkinsonism.
Topics: Humans; Insecticides; Male; Middle Aged; Organophosphorus Compounds; Parkinson Disease, Secondary; P | 1978 |
Parkinson's disease improvement after the addition of levodopa-carbidopa to anticholinergic treatment. An open controlled study.
Topics: Administration, Oral; Adult; Aged; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Female; Hu | 1978 |
The coincidence of schizophrenia and Parkinsonism: some neurochemical implications.
Topics: Aged; Delusions; Dopamine; Female; Hallucinations; Humans; Middle Aged; Parkinson Disease, Postencep | 1976 |
[Combined treatment of Parkinsonism with levopa, midantan and anticholinergic drugs].
Topics: Acetylcholine; Adult; Aged; Amantadine; Antiparkinson Agents; Cholinesterases; Drug Therapy, Combina | 1976 |
[Appearance of parkinsonian syndrome after administration of delta sleep-inducing peptide into the rat substantia nigra].
Topics: Acute Disease; Animals; Caudate Nucleus; Delta Sleep-Inducing Peptide; Injections; Parkinson Disease | 1990 |
[Parkinson syndrome after administration of acetylcholine into the caudate nuclei].
Topics: Acetylcholine; Animals; Caudate Nucleus; Disease Models, Animal; Dopamine; Electrodes, Implanted; El | 1989 |
Neuroleptic-induced Parkinson's syndrome: clinical features and results of treatment with levodopa.
Topics: Adult; Aged; Antipsychotic Agents; Benserazide; Drug Therapy, Combination; Female; Humans; Levodopa; | 1988 |
Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity in mouse brain by piroheptine and trihexyphenidyl.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Clomipramine; | 1988 |
[Modelling of the parkinsonian syndrome by the administration of kainic acid into the caudate nucleus].
Topics: Animals; Caudate Nucleus; Disease Models, Animal; Drug Evaluation, Preclinical; Electrodes, Implante | 1987 |
The adverse effect of benzhexol on memory in Parkinson's disease.
Topics: Aged; Humans; Memory Disorders; Middle Aged; Parkinson Disease, Secondary; Trihexyphenidyl | 1987 |
[Trial use of L-dopa associated with a dopa-decarboxylase inhibitor in Parkinson's syndrome].
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Diphenhydramine; Drug Therapy, Combination; g | 1974 |
[Study of extrapyramidal manifestations induced by neuroleptics].
Topics: Antiparkinson Agents; Chlorpromazine; Drug Synergism; Extrapyramidal Tracts; Fluphenazine; Haloperid | 1972 |
Fluphenazine-induced parkinsonism in the baboon: pharmacological and metabolic studies.
Topics: Animals; Basal Ganglia Diseases; Benztropine; Carbon Isotopes; Chromatography, Thin Layer; Feces; Fe | 1972 |
Lack of indication for use of antiparkinson medication. A follow-up study.
Topics: Adolescent; Adult; Female; Follow-Up Studies; Humans; Intellectual Disability; Male; Mental Disorder | 1971 |
Pink spot--is it a drug artefact?
Topics: Amitriptyline; Amobarbital; Chlorpromazine; Chromatography; Haloperidol; Humans; Mental Disorders; P | 1970 |
Transitory procaine-induced Parkinsonism.
Topics: Chronic Disease; Dihydroxyphenylalanine; Female; Humans; Middle Aged; Parkinson Disease; Parkinson D | 1971 |
The antiparkinsonian activity of monoamine oxidase inhibitors and other agents in rats and mice.
Topics: Animals; Dextroamphetamine; Diphenhydramine; Imipramine; Iproniazid; Isocarboxazid; Mice; Monoamine | 1968 |
[Prolonged use of ponalid in extapyramidal drug-induced syndromes].
Topics: Humans; Movement Disorders; Parkinson Disease; Parkinson Disease, Secondary; Salivary Gland Diseases | 1966 |