trihexyphenidyl has been researched along with Ataxia Telangiectasia in 1 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Severe dystonia was presented in late stage of this disease." | 5.56 | Trihexyphenidyl for treatment of dystonia in ataxia telangiectasia: a case report. ( Jia, Y; Li, M; Qi, X; Wang, S; Wang, Y; Zhang, L, 2020) |
| "Severe dystonia was presented in late stage of this disease." | 1.56 | Trihexyphenidyl for treatment of dystonia in ataxia telangiectasia: a case report. ( Jia, Y; Li, M; Qi, X; Wang, S; Wang, Y; Zhang, L, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 1 |
| Jia, Y | 1 |
| Qi, X | 1 |
| Li, M | 1 |
| Wang, S | 1 |
| Wang, Y | 1 |
1 other study available for trihexyphenidyl and Ataxia Telangiectasia
| Article | Year |
|---|---|
Trihexyphenidyl for treatment of dystonia in ataxia telangiectasia: a case report.
Topics: Ataxia Telangiectasia; Child; Dystonia; Dystonic Disorders; Humans; Male; Mutation; Phenotype; Trihe | 2020 |