trihexyphenidyl has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brait, K | 1 |
| Fahn, S | 1 |
| Schwarz, GA | 1 |
2 other studies available for trihexyphenidyl and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Letter: Symptomatic care of patients with amyotrophic lateral sclerosis..
Topics: Amyotrophic Lateral Sclerosis; Anesthesia, General; Humans; Trihexyphenidyl | 1976 |
Sporadic and familial parkinsonism and motor neuron disease.
Topics: Aged; Amantadine; Amyotrophic Lateral Sclerosis; Cerebellar Diseases; Corpus Striatum; Dihydroxyphen | 1973 |