trihexyphenidyl has been researched along with Age-Related Memory Disorders in 11 studies
Trihexyphenidyl: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both studies yielded significant correlations between memory impairment and dosage levels of benzhexol." | 1.27 | The adverse effect of benzhexol on memory in Parkinson's disease. ( Berrios, GE; Miller, E; Politynska, B, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pomara, N | 4 |
| Sidtis, J | 1 |
| Yi, L | 1 |
| Belzer, K | 2 |
| Facelle, TM | 1 |
| Willoughby, LM | 2 |
| Sidtis, JJ | 3 |
| Wesnes, K | 1 |
| Hernando, R | 1 |
| De La Pena, C | 1 |
| Lee, WK | 1 |
| Yu, ZH | 1 |
| Lee, CC | 1 |
| Kajimura, N | 1 |
| Mizuki, Y | 1 |
| Kai, S | 1 |
| Suetsugi, M | 1 |
| Yamada, M | 1 |
| Okuma, T | 1 |
| Schelosky, L | 1 |
| Benke, T | 1 |
| Poewe, WH | 1 |
| McEvoy, JP | 2 |
| Robinson, ML | 1 |
| McCue, M | 1 |
| Spring, B | 1 |
| Mohs, RC | 1 |
| Lavori, PW | 1 |
| Farr, RM | 1 |
| Miller, E | 1 |
| Berrios, GE | 1 |
| Politynska, B | 1 |
5 trials available for trihexyphenidyl and Age-Related Memory Disorders
| Article | Year |
|---|---|
Retrograde facilitation of verbal memory by trihexyphenidyl in healthy elderly with and without the APOE epsilon4 allele.
Topics: Aged; Analysis of Variance; Apolipoprotein E4; Dose-Response Relationship, Drug; Double-Blind Method | 2010 |
Increased anticholinergic challenge-induced memory impairment associated with the APOE-epsilon4 allele in the elderly: a controlled pilot study.
Topics: Aged; Alleles; Analysis of Variance; Apolipoprotein E4; Apolipoproteins E; Case-Control Studies; Cho | 2004 |
Increased mental slowing associated with the APOE epsilon4 allele after trihexyphenidyl oral anticholinergic challenge in healthy elderly.
Topics: Administration, Oral; Aged; Alleles; Apolipoprotein E4; Awareness; Cholinergic Antagonists; Cognitio | 2008 |
A double-blind crossover comparison of antiparkinson drug therapy: amantadine versus anticholinergics in 90 normal volunteers, with an emphasis on differential effects on memory function.
Topics: Adult; Age Factors; Aged; Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Cli | 1987 |
Effects of amantadine and trihexyphenidyl on memory in elderly normal volunteers.
Topics: Age Factors; Aged; Amantadine; Confusion; Dose-Response Relationship, Drug; Double-Blind Method; Fem | 1987 |
6 other studies available for trihexyphenidyl and Age-Related Memory Disorders
| Article | Year |
|---|---|
Apolipoprotein E epsilon4 and anticholinergic cognitive toxicity.
Topics: Aged; Alleles; Apolipoprotein E4; Cardiovascular Diseases; Cholinergic Antagonists; Cognition Disord | 2009 |
Delayed neurological sequelae after carbon monoxide poisoning.
Topics: Adult; Antiparkinson Agents; Brain; Brain Infarction; Carbon Monoxide Poisoning; Cognition Disorders | 2008 |
Memory and cognitive impairments in a case of long-term trihexyphenidyl abuse.
Topics: Cognition Disorders; Electroencephalography; Humans; Male; Memory Disorders; Middle Aged; Psychologi | 1993 |
Effects of treatment with trihexyphenidyl on cognitive function in early Parkinson's disease.
Topics: Adult; Aged; Cognition Disorders; Female; Humans; Intelligence Tests; Male; Memory Disorders; Middle | 1991 |
Drug side effects and the double-blind design.
Topics: Amantadine; Confusion; Double-Blind Method; Humans; Memory Disorders; Research Design; Trihexyphenid | 1988 |
The adverse effect of benzhexol on memory in Parkinson's disease.
Topics: Aged; Humans; Memory Disorders; Middle Aged; Parkinson Disease, Secondary; Trihexyphenidyl | 1987 |