triheptanoin has been researched along with Disease Models, Animal in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 13 (86.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Shirley, M | 1 |
| Du, H; Guo, L; Pascual, JM; Sun, H; Tandon, N; Tian, J; Wang, L; Yuan, X | 1 |
| Berressem, D; Eckert, GP; Klein, J; Koch, K; Konietzka, J; Thinnes, A | 1 |
| Barile, ZJ; Fogle, KJ; Gutierrez, AC; Hertzler, JI; McCardell, CS; Novak, MO; Palladino, MJ; Satterfield, SL; Shon, JH; Smith, AR | 1 |
| Borges, K; Hodson, MP; McDonald, TS; Tan, KN | 1 |
| Borges, K; Hadera, MG; McDonald, TS; Smeland, OB; Sonnewald, U; Tan, KN | 1 |
| Francis, JS; Leone, P; Markov, V | 1 |
| Aja, S; Degano, AL; Li, Q; Park, MJ; Penati, J; Roe, CR; Ronnett, GV; Zhuo, J | 1 |
| Klein, J; Koch, K; Schwarzkopf, TM | 1 |
| Amorim, PA; Doenst, T; Nguyen, TD; Schwarzer, M; Shingu, Y | 1 |
| Behringer, S; Spiekerkoetter, U; Tucci, S | 1 |
| Borges, K; Stoll, J; Sweetman, L; Willis, S | 1 |
| Borges, K; Sweetman, L; Thomas, NK; Willis, S | 1 |
| Aso, E; Calpena, A; Escolano, C; Ferrer, I; Halbaut, L; Joda, L; Perales, JC; Semak, V; Semakova, J | 1 |
| Borges, K; Kim, TH; Petrou, S; Reid, CA | 1 |
1 review(s) available for triheptanoin and Disease Models, Animal
| Article | Year |
|---|---|
Triheptanoin: First Approval.
Topics: Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease Models, Animal; Drug Approval; Drug Evaluation, Preclinical; Energy Metabolism; Fatty Acids; Humans; Lipid Metabolism, Inborn Errors; Oxidation-Reduction; Treatment Outcome; Triglycerides; United States; United States Food and Drug Administration | 2020 |
14 other study(ies) available for triheptanoin and Disease Models, Animal
| Article | Year |
|---|---|
Triheptanoin Mitigates Brain ATP Depletion and Mitochondrial Dysfunction in a Mouse Model of Alzheimer's Disease.
Topics: Adenosine Triphosphate; Alzheimer Disease; Animals; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Fatty Acids; Hippocampus; Mice; Mice, Transgenic; Mitochondria; Oxidation-Reduction; Triglycerides | 2020 |
Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice.
Topics: 3-Hydroxybutyric Acid; Adrenergic beta-Antagonists; Animals; Brain; Brain Ischemia; Citric Acid; Diet, Carbohydrate Loading; Diet, High-Fat; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Glucose; Infarction, Middle Cerebral Artery; Ketone Bodies; Liver; Mice; Microdialysis; Propranolol; Soybean Oil; Succinic Acid; Triglycerides | 2017 |
Ketogenic and anaplerotic dietary modifications ameliorate seizure activity in Drosophila models of mitochondrial encephalomyopathy and glycolytic enzymopathy.
Topics: Animals; Diet, Ketogenic; Dietary Supplements; Disease Models, Animal; Drosophila; Drosophila Proteins; Glycolysis; Ketone Bodies; Mitochondrial Encephalomyopathies; Mitochondrial Proton-Translocating ATPases; Seizures; Triglycerides | 2019 |
Alterations of hippocampal glucose metabolism by even versus uneven medium chain triglycerides.
Topics: Animals; Anticonvulsants; Caprylates; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Glucose; Hippocampus; Male; Mice; Mice, Inbred Strains; Seizures; Structure-Activity Relationship; Triglycerides | 2014 |
Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsy.
Topics: Animals; Cerebral Cortex; Citric Acid Cycle; Disease Models, Animal; Epilepsy; Hippocampus; Male; Mice; Pilocarpine; Random Allocation; Triglycerides | 2014 |
Dietary triheptanoin rescues oligodendrocyte loss, dysmyelination and motor function in the nur7 mouse model of Canavan disease.
Topics: Adenosine Triphosphate; Amidohydrolases; Animals; Aspartic Acid; Canavan Disease; Disease Models, Animal; Mice; Myelin Sheath; Oligodendroglia; Triglycerides | 2014 |
Anaplerotic triheptanoin diet enhances mitochondrial substrate use to remodel the metabolome and improve lifespan, motor function, and sociability in MeCP2-null mice.
Topics: Animals; Behavior, Animal; Citric Acid Cycle; Diet; Disease Models, Animal; Gene Expression; Humans; Lipid Metabolism; Longevity; Male; Metabolome; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Phenotype; Rett Syndrome; Triglycerides | 2014 |
Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin.
Topics: Adenosine Triphosphate; Animals; Body Weight; Brain; Brain Ischemia; Disease Models, Animal; Electron Transport; Fatty Acids; Female; Glucose; Glutamic Acid; Infarction, Middle Cerebral Artery; Matrix Metalloproteinases; Mice; Mitochondria; Motor Activity; Oxygen Consumption; Severity of Illness Index; Stroke; Triglycerides | 2015 |
Triheptanoin Alleviates Ventricular Hypertrophy and Improves Myocardial Glucose Oxidation in Rats With Pressure Overload.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Echocardiography, Doppler; Glucose; Hypertrophy, Left Ventricular; Male; Myocardial Contraction; Myocardium; Oxidation-Reduction; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Reference Values; Treatment Outcome; Triglycerides | 2015 |
De novo fatty acid biosynthesis and elongation in very long-chain acyl-CoA dehydrogenase-deficient mice supplemented with odd or even medium-chain fatty acids.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Animals; Congenital Bone Marrow Failure Syndromes; Dietary Fats; Disease Models, Animal; Fatty Acids; Female; Lipid Metabolism, Inborn Errors; Liver; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Diseases; Muscular Diseases; Myocardium; Oxidation-Reduction; Peroxisomes; Triglycerides | 2015 |
Anticonvulsant effects of a triheptanoin diet in two mouse chronic seizure models.
Topics: Animals; Anticonvulsants; Brain; Disease Models, Animal; Epilepsy; Mice; Seizures; Triglycerides | 2010 |
Triheptanoin in acute mouse seizure models.
Topics: Acute Disease; Animals; Anticonvulsants; Disease Models, Animal; Mice; Mice, Inbred C3H; Pentylenetetrazole; Seizures; Triglycerides | 2012 |
Triheptanoin supplementation to ketogenic diet curbs cognitive impairment in APP/PS1 mice used as a model of familial Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Diet, Ketogenic; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Maze Learning; Mice; Mice, Transgenic; Real-Time Polymerase Chain Reaction; Triglycerides | 2013 |
Triheptanoin reduces seizure susceptibility in a syndrome-specific mouse model of generalized epilepsy.
Topics: Age Factors; Animals; Anticonvulsants; Dietary Supplements; Disease Models, Animal; Disease Susceptibility; Epilepsy, Generalized; Mice; Mice, Inbred DBA; Mice, Transgenic; Seizures; Triglycerides | 2013 |