trigonelline has been researched along with Overweight in 2 studies
trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
Overweight: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Overweight persons (n = 118) were randomized to consume a dark roast [rich in N-methylpyridinium (NMP)] or medium roast (rich in caffeoylquinic acids, trigonelline) coffee blend for 3 months, after a washout period of 4 weeks." | 5.20 | Cardiometabolic effects of two coffee blends differing in content for major constituents in overweight adults: a randomized controlled trial. ( Bytof, G; Gärtner, B; Hofmann, T; Kempf, K; Kolb, H; Lang, R; Lantz, I; Martin, S; Stiebitz, H, 2015) |
| "We conducted a randomized crossover trial of the effects of 12 g decaffeinated coffee, 1 g chlorogenic acid, 500 mg trigonelline, and placebo (1 g mannitol) on glucose and insulin concentrations during a 2-h oral glucose tolerance test (OGTT) in 15 overweight men." | 5.14 | Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance. ( Heine, RJ; Meeuse, JC; Olthof, MR; Seebus, E; van Dam, RM; van Dijk, AE, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kempf, K | 1 |
| Kolb, H | 1 |
| Gärtner, B | 1 |
| Bytof, G | 1 |
| Stiebitz, H | 1 |
| Lantz, I | 1 |
| Lang, R | 1 |
| Hofmann, T | 1 |
| Martin, S | 1 |
| van Dijk, AE | 1 |
| Olthof, MR | 1 |
| Meeuse, JC | 1 |
| Seebus, E | 1 |
| Heine, RJ | 1 |
| van Dam, RM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Health Effects of Coffee Consumption[NCT01759329] | 118 participants (Actual) | Interventional | 2011-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for trigonelline and Overweight
| Article | Year |
|---|---|
Cardiometabolic effects of two coffee blends differing in content for major constituents in overweight adults: a randomized controlled trial.
Topics: Adiponectin; Adolescent; Adult; Aged; Alkaloids; Blood Glucose; Blood Pressure; Body Mass Index; Bod | 2015 |
Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance.
Topics: Alkaloids; Blood Glucose; Caffeine; Chlorogenic Acid; Coffee; Cross-Over Studies; Glucose Tolerance | 2009 |