trigonelline has been researched along with Obesity in 3 studies
trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Considering its high bioavailability in humans and the results of this study, trigonelline may have potential as an anti-obesity compound." | 1.62 | Trigonelline induces browning in 3T3-L1 white adipocytes. ( Choi, M; Mukherjee, S; Yun, JW, 2021) |
| "Trigonelline is a natural alkaloid mainly found in Trigonella Foenum Graecum (fenugreek) Fabaceae and other edible plants with a variety of medicinal applications." | 1.40 | Trigonelline attenuates the adipocyte differentiation and lipid accumulation in 3T3-L1 cells. ( Arasu, MV; Choi, GJ; Choi, KC; Ilavenil, S; Kim, DH; Lee, JC; Mayakrishnan, V; Park, HS; Roh, SG, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Costa, MC | 1 |
| Lima, TFO | 1 |
| Arcaro, CA | 1 |
| Inacio, MD | 1 |
| Batista-Duharte, A | 1 |
| Carlos, IZ | 1 |
| Spolidorio, LC | 1 |
| Assis, RP | 1 |
| Brunetti, IL | 1 |
| Baviera, AM | 1 |
| Choi, M | 1 |
| Mukherjee, S | 1 |
| Yun, JW | 1 |
| Ilavenil, S | 1 |
| Arasu, MV | 1 |
| Lee, JC | 1 |
| Kim, DH | 1 |
| Roh, SG | 1 |
| Park, HS | 1 |
| Choi, GJ | 1 |
| Mayakrishnan, V | 1 |
| Choi, KC | 1 |
3 other studies available for trigonelline and Obesity
| Article | Year |
|---|---|
Trigonelline and curcumin alone, but not in combination, counteract oxidative stress and inflammation and increase glycation product detoxification in the liver and kidney of mice with high-fat diet-induced obesity.
Topics: Alkaloids; Animals; Antioxidants; Biomarkers; Blood Glucose; Body Weight; Curcumin; Diet, High-Fat; | 2020 |
Trigonelline induces browning in 3T3-L1 white adipocytes.
Topics: 3T3-L1 Cells; Adipocytes, Brown; Adipocytes, White; Alkaloids; Animals; Humans; Mice; Obesity | 2021 |
Trigonelline attenuates the adipocyte differentiation and lipid accumulation in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Alkaloids; Animals; Cell Proliferation; Drug Evaluation, Pre | 2014 |