trigonelline has been researched along with Lung Neoplasms in 2 studies
trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trigonelline is a plant alkaloid, a significant constituent in coffee, and has shown health benefits in several disorders." | 1.72 | Multiple targets of Nrf 2 inhibitor; trigonelline in combating urethane-induced lung cancer by caspase-executioner apoptosis, cGMP and limitation of cyclin D1 and Bcl2. ( Abo-Youssef, AM; Hamzawy, MA; Khalaf, MM; Malak, MN, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamzawy, MA | 1 |
| Abo-Youssef, AM | 1 |
| Malak, MN | 1 |
| Khalaf, MM | 1 |
| Fouzder, C | 1 |
| Mukhuty, A | 1 |
| Mukherjee, S | 1 |
| Malick, C | 1 |
| Kundu, R | 1 |
2 other studies available for trigonelline and Lung Neoplasms
| Article | Year |
|---|---|
Multiple targets of Nrf 2 inhibitor; trigonelline in combating urethane-induced lung cancer by caspase-executioner apoptosis, cGMP and limitation of cyclin D1 and Bcl2.
Topics: Alkaloids; Animals; Apoptosis; Caspases; Cyclin D1; Enzyme Inhibitors; Lung Neoplasms; Mice; Mice, I | 2022 |
Trigonelline inhibits Nrf2 via EGFR signalling pathway and augments efficacy of Cisplatin and Etoposide in NSCLC cells.
Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Prolife | 2021 |