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trigonelline and Inflammation

trigonelline has been researched along with Inflammation in 5 studies

trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"These findings suggest that trigonelline protects diabetic pregnancy partly by suppressing inflammation, regulating the secretion of adipocytokines, increasing β-cell mass, replication, and decreasing β-cell apoptosis."7.85Trigonelline Inhibits Inflammation and Protects β Cells to Prevent Fetal Growth Restriction during Pregnancy in a Mouse Model of Diabetes. ( Du, XH; Qian, GS; Zhang, Z; Zhou, JY, 2017)
"These findings suggest that trigonelline protects diabetic pregnancy partly by suppressing inflammation, regulating the secretion of adipocytokines, increasing β-cell mass, replication, and decreasing β-cell apoptosis."3.85Trigonelline Inhibits Inflammation and Protects β Cells to Prevent Fetal Growth Restriction during Pregnancy in a Mouse Model of Diabetes. ( Du, XH; Qian, GS; Zhang, Z; Zhou, JY, 2017)
"Trigonelline is a plant alkaloid that has generated interest for its neuroprotective roles in brain pathology."1.56Trigonelline protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activating the PI3K/Akt pathway. ( Fan, X; Jiang, C; Li, J; Qiu, Z; Su, Y; Wang, K; Xue, S; Yao, L, 2020)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Costa, MC1
Lima, TFO1
Arcaro, CA1
Inacio, MD1
Batista-Duharte, A1
Carlos, IZ1
Spolidorio, LC1
Assis, RP1
Brunetti, IL1
Baviera, AM1
Qiu, Z1
Wang, K1
Jiang, C1
Su, Y1
Fan, X1
Li, J1
Xue, S1
Yao, L1
A Nazir, L1
Tanveer, MA1
Umar, SA1
Love, S1
Divya, G1
Tasduq, SA1
Zhou, JY1
Du, XH1
Zhang, Z1
Qian, GS1

Other Studies

5 other studies available for trigonelline and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Trigonelline and curcumin alone, but not in combination, counteract oxidative stress and inflammation and increase glycation product detoxification in the liver and kidney of mice with high-fat diet-induced obesity.
    The Journal of nutritional biochemistry, 2020, Volume: 76

    Topics: Alkaloids; Animals; Antioxidants; Biomarkers; Blood Glucose; Body Weight; Curcumin; Diet, High-Fat;

2020
Trigonelline protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activating the PI3K/Akt pathway.
    Chemico-biological interactions, 2020, Feb-01, Volume: 317

    Topics: Alkaloids; Animals; Brain Ischemia; Cell Survival; Chromones; Glucose; Hippocampus; Inflammation; Mo

2020
Inhibition of Ultraviolet-B Radiation Induced Photodamage by Trigonelline Through Modulation of Mitogen Activating Protein Kinases and Nuclear Factor-κB Signaling Axis in Skin.
    Photochemistry and photobiology, 2021, Volume: 97, Issue:4

    Topics: Alkaloids; Animals; Collagen; Fibroblasts; Inflammation; Mice; Mitogen-Activated Protein Kinases; Mi

2021
Trigonelline Inhibits Inflammation and Protects β Cells to Prevent Fetal Growth Restriction during Pregnancy in a Mouse Model of Diabetes.
    Pharmacology, 2017, Volume: 100, Issue:5-6

    Topics: Alkaloids; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Female;

2017