trigonelline has been researched along with Diabetes Mellitus in 5 studies
trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trigonelline has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and it has been shown to reduce diabetic auditory neuropathy and platelet aggregation." | 6.48 | Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease. ( Chan, L; Zhou, J; Zhou, S, 2012) |
| "Trigonelline has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and it has been shown to reduce diabetic auditory neuropathy and platelet aggregation." | 2.48 | Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease. ( Chan, L; Zhou, J; Zhou, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, Y | 1 |
| Dai, X | 1 |
| Cao, Y | 1 |
| Wang, X | 1 |
| Lu, J | 1 |
| Xie, L | 1 |
| Liu, K | 1 |
| Li, X | 1 |
| Mohamadi, N | 1 |
| Sharififar, F | 1 |
| Pournamdari, M | 1 |
| Ansari, M | 1 |
| Adams, GG | 1 |
| Imran, S | 1 |
| Wang, S | 1 |
| Mohammad, A | 1 |
| Kok, MS | 1 |
| Gray, DA | 1 |
| Channell, GA | 1 |
| Harding, SE | 1 |
| Yoshinari, O | 1 |
| Sato, H | 1 |
| Igarashi, K | 1 |
| Zhou, J | 1 |
| Chan, L | 1 |
| Zhou, S | 1 |
4 reviews available for trigonelline and Diabetes Mellitus
| Article | Year |
|---|---|
The neuroprotective and antidiabetic effects of trigonelline: A review of signaling pathways and molecular mechanisms.
Topics: Alkaloids; Diabetes Mellitus; Humans; Hypoglycemic Agents; Neuroprotective Agents; Signal Transducti | 2023 |
A Review on Biosynthesis, Analytical Techniques, and Pharmacological Activities of Trigonelline as a Plant Alkaloid.
Topics: Alkaloids; Animals; Anti-Infective Agents; Anticarcinogenic Agents; Antioxidants; Cardiovascular Dis | 2018 |
The hypoglycemic effect of pumpkin seeds, Trigonelline (TRG), Nicotinic acid (NA), and D-Chiro-inositol (DCI) in controlling glycemic levels in diabetes mellitus.
Topics: Alkaloids; Animals; Blood Glucose; Cucurbita; Diabetes Mellitus; Humans; Hypoglycemic Agents; Inosit | 2014 |
Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease.
Topics: Alkaloids; Animals; Central Nervous System Diseases; Diabetes Mellitus; Humans; Hypoglycemic Agents; | 2012 |
1 other study available for trigonelline and Diabetes Mellitus
| Article | Year |
|---|---|
Anti-diabetic effects of pumpkin and its components, trigonelline and nicotinic acid, on Goto-Kakizaki rats.
Topics: Alkaloids; Animals; Biomarkers; Blood Glucose; Cucurbita; Diabetes Mellitus; Fasting; Glucose Tolera | 2009 |