trigonelline has been researched along with Diabetes Mellitus, Type 1 in 3 studies
trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trigonelline treatment restored the above mentioned parameters." | 1.48 | Trigonelline inhibits caspase 3 to protect β cells apoptosis in streptozotocin-induced type 1 diabetic mice. ( Du, X; Liu, L; Zhang, Z; Zhou, J, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, L | 1 |
| Du, X | 1 |
| Zhang, Z | 1 |
| Zhou, J | 1 |
| Folwarczna, J | 1 |
| Janas, A | 1 |
| Pytlik, M | 1 |
| Cegieła, U | 1 |
| Śliwiński, L | 1 |
| Krivošíková, Z | 1 |
| Štefíková, K | 1 |
| Gajdoš, M | 1 |
| Dellow, WJ | 1 |
| Chambers, ST | 1 |
| Lever, M | 1 |
| Lunt, H | 1 |
| Robson, RA | 1 |
3 other studies available for trigonelline and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Trigonelline inhibits caspase 3 to protect β cells apoptosis in streptozotocin-induced type 1 diabetic mice.
Topics: Alkaloids; Animals; Blood Glucose; Body Weight; Caspase 3; Caspase Inhibitors; Cytoprotection; Diabe | 2018 |
Effects of Trigonelline, an Alkaloid Present in Coffee, on Diabetes-Induced Disorders in the Rat Skeletal System.
Topics: Alkaloids; Animals; Biomarkers; Bone Density; Coffea; Diabetes Complications; Diabetes Mellitus, Exp | 2016 |
Elevated glycine betaine excretion in diabetes mellitus patients is associated with proximal tubular dysfunction and hyperglycemia.
Topics: Adult; Aged; Aged, 80 and over; Alkaloids; Betaine; Biomarkers; Carnitine; Creatinine; Diabetes Mell | 1999 |