trigonelline has been researched along with Diabetes Mellitus, Adult-Onset in 11 studies
trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The bioavailability and the distribution of each compound and its metabolites also contribute to coffee mechanisms of action." | 2.50 | Coffee components and cardiovascular risk: beneficial and detrimental effects. ( Buscemi, S; Galvano, F; Godos, J; Grosso, G; Li Volti, G; Marventano, S; Pluchinotta, FR, 2014) |
| " However, to the best of our knowledge, no study has investigated the pharmacokinetic parameters of purified standardized T." | 1.72 | A novel UPLC-MS/MS method for simultaneous quantification of trigonelline, 4-hydroxyisoleucine, and diosgenin from Trigonella foenum-graecum extract: Application to pharmacokinetic study in healthy and type 2 diabetic rats. ( Banerjee, D; Dubey, SK; Katiyar, C; Krishna, KV; Narwaria, A; Taliyan, R; Tandon, N; Wadhwa, G; Yadav, SS, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Mellbye, FB | 1 |
| Jeppesen, PB | 1 |
| Hermansen, K | 1 |
| Gregersen, S | 1 |
| Wadhwa, G | 1 |
| Krishna, KV | 1 |
| Taliyan, R | 1 |
| Tandon, N | 1 |
| Yadav, SS | 1 |
| Banerjee, D | 1 |
| Narwaria, A | 1 |
| Katiyar, C | 1 |
| Dubey, SK | 1 |
| Ludwig, IA | 1 |
| Clifford, MN | 1 |
| Lean, ME | 1 |
| Ashihara, H | 1 |
| Crozier, A | 1 |
| Godos, J | 1 |
| Pluchinotta, FR | 1 |
| Marventano, S | 1 |
| Buscemi, S | 1 |
| Li Volti, G | 1 |
| Galvano, F | 1 |
| Grosso, G | 1 |
| Tharaheswari, M | 1 |
| Jayachandra Reddy, N | 1 |
| Kumar, R | 1 |
| Varshney, KC | 1 |
| Kannan, M | 1 |
| Sudha Rani, S | 1 |
| Aldakinah, AA | 1 |
| Al-Shorbagy, MY | 1 |
| Abdallah, DM | 1 |
| El-Abhar, HS | 1 |
| Yoshinari, O | 2 |
| Igarashi, K | 2 |
| Zhou, J | 1 |
| Zhou, S | 1 |
| Zeng, S | 1 |
| Takenake, A | 1 |
| Ross, CM | 1 |
| Dellow, WJ | 1 |
| Chambers, ST | 1 |
| Lever, M | 1 |
| Lunt, H | 1 |
| Robson, RA | 1 |
2 reviews available for trigonelline and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Coffee: biochemistry and potential impact on health.
Topics: Alkaloids; Animals; Antioxidants; Caffeine; Cardiovascular Diseases; Chlorogenic Acid; Coffee; Diabe | 2014 |
Coffee components and cardiovascular risk: beneficial and detrimental effects.
Topics: Alkaloids; Caffeine; Cardiovascular Diseases; Cardiovascular System; Chlorogenic Acid; Coffee; Diabe | 2014 |
9 other studies available for trigonelline and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Cafestol, a Bioactive Substance in Coffee, Stimulates Insulin Secretion and Increases Glucose Uptake in Muscle Cells: Studies in Vitro.
Topics: Alkaloids; Animals; Butylene Glycols; Caffeic Acids; Chlorogenic Acid; Coffee; Diabetes Mellitus, Ty | 2015 |
A novel UPLC-MS/MS method for simultaneous quantification of trigonelline, 4-hydroxyisoleucine, and diosgenin from Trigonella foenum-graecum extract: Application to pharmacokinetic study in healthy and type 2 diabetic rats.
Topics: Alkaloids; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diosgenin; Female; I | 2022 |
Trigonelline and diosgenin attenuate ER stress, oxidative stress-mediated damage in pancreas and enhance adipose tissue PPARγ activity in type 2 diabetic rats.
Topics: Adipose Tissue; Alkaloids; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet | 2014 |
Trigonelline and vildagliptin antidiabetic effect: improvement of insulin signalling pathway.
Topics: Adamantane; Alkaloids; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabet | 2017 |
Anti-diabetic effect of trigonelline and nicotinic acid, on KK-A(y) mice.
Topics: Alkaloids; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Glucokinase; Glucose-6-Phosph | 2010 |
Experimental diabetes treated with trigonelline: effect on β cell and pancreatic oxidative parameters.
Topics: Alkaloids; Animals; Antioxidants; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabe | 2013 |
Trigonelline ameliorates oxidative stress in type 2 diabetic Goto-Kakizaki rats.
Topics: Alkaloids; Animals; Catalase; Diabetes Mellitus, Type 2; Glutathione; Glutathione Peroxidase; Humans | 2013 |
Coffee consumption and development of type 2 diabetes.
Topics: Alkaloids; Coffee; Diabetes Mellitus, Type 2; Humans | 2005 |
Elevated glycine betaine excretion in diabetes mellitus patients is associated with proximal tubular dysfunction and hyperglycemia.
Topics: Adult; Aged; Aged, 80 and over; Alkaloids; Betaine; Biomarkers; Carnitine; Creatinine; Diabetes Mell | 1999 |