trigonelline has been researched along with Brain Ischemia in 2 studies
trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Stroke is devastating with a limited choice of intervention." | 5.51 | Trigonelline therapy confers neuroprotection by reduced glutathione mediated myeloperoxidase expression in animal model of ischemic stroke. ( Bhattacharya, P; Borah, A; Dave, KR; Kalia, K; Kaur, H; Pravalika, K; Saraf, J; Sarmah, D; Vats, K; Wanve, M; Yavagal, DR, 2019) |
| "Trigonelline is a plant alkaloid that has generated interest for its neuroprotective roles in brain pathology." | 1.56 | Trigonelline protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activating the PI3K/Akt pathway. ( Fan, X; Jiang, C; Li, J; Qiu, Z; Su, Y; Wang, K; Xue, S; Yao, L, 2020) |
| "Stroke is devastating with a limited choice of intervention." | 1.51 | Trigonelline therapy confers neuroprotection by reduced glutathione mediated myeloperoxidase expression in animal model of ischemic stroke. ( Bhattacharya, P; Borah, A; Dave, KR; Kalia, K; Kaur, H; Pravalika, K; Saraf, J; Sarmah, D; Vats, K; Wanve, M; Yavagal, DR, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qiu, Z | 1 |
| Wang, K | 1 |
| Jiang, C | 1 |
| Su, Y | 1 |
| Fan, X | 1 |
| Li, J | 1 |
| Xue, S | 1 |
| Yao, L | 1 |
| Pravalika, K | 1 |
| Sarmah, D | 1 |
| Kaur, H | 1 |
| Vats, K | 1 |
| Saraf, J | 1 |
| Wanve, M | 1 |
| Kalia, K | 1 |
| Borah, A | 1 |
| Yavagal, DR | 1 |
| Dave, KR | 1 |
| Bhattacharya, P | 1 |
2 other studies available for trigonelline and Brain Ischemia
| Article | Year |
|---|---|
Trigonelline protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activating the PI3K/Akt pathway.
Topics: Alkaloids; Animals; Brain Ischemia; Cell Survival; Chromones; Glucose; Hippocampus; Inflammation; Mo | 2020 |
Trigonelline therapy confers neuroprotection by reduced glutathione mediated myeloperoxidase expression in animal model of ischemic stroke.
Topics: Alkaloids; Aniline Compounds; Animals; Antioxidants; Blotting, Western; Brain Ischemia; Cerebral Inf | 2019 |