trigonelline has been researched along with Age-Related Memory Disorders in 3 studies
trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trigonelline (TRG) is a naturally occurring alkaloid, commonly isolated from fenugreek and coffee beans." | 1.48 | Trigonelline insulates against oxidative stress, proinflammatory cytokines and restores BDNF levels in lipopolysaccharide induced cognitive impairment in adult mice. ( Chowdhury, AA; Gawali, NB; Juvekar, AR; Munshi, R, 2018) |
| "Trigonelline-treated LPS-challenged rats showed improved spatial recognition memory in Y maze, discrimination ratio in novel object discrimination test, and retention and recall in passive avoidance paradigm." | 1.48 | Trigonelline mitigates lipopolysaccharide-induced learning and memory impairment in the rat due to its anti-oxidative and anti-inflammatory effect. ( Alavi, M; Baluchnejadmojarad, T; Esmaeil-Jamaat, E; Khalili, M; Roghani, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Farid, MM | 1 |
| Yang, X | 1 |
| Kuboyama, T | 1 |
| Tohda, C | 1 |
| Chowdhury, AA | 1 |
| Gawali, NB | 1 |
| Munshi, R | 1 |
| Juvekar, AR | 1 |
| Khalili, M | 1 |
| Alavi, M | 1 |
| Esmaeil-Jamaat, E | 1 |
| Baluchnejadmojarad, T | 1 |
| Roghani, M | 1 |
3 other studies available for trigonelline and Age-Related Memory Disorders
| Article | Year |
|---|---|
Trigonelline recovers memory function in Alzheimer's disease model mice: evidence of brain penetration and target molecule.
Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Atroph | 2020 |
Trigonelline insulates against oxidative stress, proinflammatory cytokines and restores BDNF levels in lipopolysaccharide induced cognitive impairment in adult mice.
Topics: Alkaloids; Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Cytokine | 2018 |
Trigonelline mitigates lipopolysaccharide-induced learning and memory impairment in the rat due to its anti-oxidative and anti-inflammatory effect.
Topics: Acetylcholinesterase; Aged; Alkaloids; Animals; Antioxidants; Brain; Humans; Learning Disabilities; | 2018 |