trigonelline has been researched along with Acute Confusional Senile Dementia in 5 studies
trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trigonelline is an alkaloid found in medicinal plants such as fenugreek seeds and coffee beans with neuroprotective potential and according to existing evidences, a favorable agent for treatment of neurodegenerative disorders." | 1.51 | Trigonelline protects hippocampus against intracerebral Aβ(1-40) as a model of Alzheimer's disease in the rat: insights into underlying mechanisms. ( Baluchnejadmojarad, T; Fahanik-Babaei, J; Nikbakht, F; Roghani, M, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zia, SR | 1 |
| Wasim, M | 1 |
| Ahmad, S | 1 |
| Farid, MM | 1 |
| Yang, X | 1 |
| Kuboyama, T | 1 |
| Tohda, C | 1 |
| Chowdhury, AA | 1 |
| Gawali, NB | 1 |
| Bulani, VD | 1 |
| Kothavade, PS | 1 |
| Mestry, SN | 1 |
| Deshpande, PS | 1 |
| Juvekar, AR | 1 |
| Fahanik-Babaei, J | 1 |
| Baluchnejadmojarad, T | 1 |
| Nikbakht, F | 1 |
| Roghani, M | 1 |
| Makowska, J | 1 |
| Szczesny, D | 1 |
| Lichucka, A | 1 |
| Giełdoń, A | 1 |
| Chmurzyński, L | 1 |
| Kaliszan, R | 1 |
5 other studies available for trigonelline and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Unlocking therapeutic potential of trigonelline through molecular docking as a promising approach for treating diverse neurological disorders.
Topics: Alkaloids; Alzheimer Disease; Humans; Molecular Docking Simulation; Nervous System Diseases | 2023 |
Trigonelline recovers memory function in Alzheimer's disease model mice: evidence of brain penetration and target molecule.
Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Atroph | 2020 |
In vitro antiglycating effect and in vivo neuroprotective activity of Trigonelline in d-galactose induced cognitive impairment.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Br | 2018 |
Trigonelline protects hippocampus against intracerebral Aβ(1-40) as a model of Alzheimer's disease in the rat: insights into underlying mechanisms.
Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Cytokines; Disease Model | 2019 |
Preliminary studies on trigonelline as potential anti-Alzheimer disease agent: determination by hydrophilic interaction liquid chromatography and modeling of interactions with beta-amyloid.
Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Biological Availability; Blood-Brain Barrier; B | 2014 |