Page last updated: 2024-08-17

trifluridine and Neutropenia

trifluridine has been researched along with Neutropenia in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (47.62)24.3611
2020's11 (52.38)2.80

Authors

AuthorsStudies
Arkenau, HT; Benhadji, KA; Doi, T; Falcone, A; George, B; Hochster, H; Ilson, DH; Makris, L; Mayer, R; Ohtsu, A; Shitara, K; Tabernero, J; Van Cutsem, E; Yoshino, T1
Amor Urbano, M; Aviñó Tarazona, V; Bayo Calero, J; Domínguez Senín, L; Rodriguez Garcés, MY; Santos-Rubio, MD1
Esaki, T; Fukuoka, S; Kajiwara, T; Kumekawa, Y; Makiyama, A; Masuishi, T; Moriwaki, T; Shimada, Y; Shiroyama, M; Takashima, A; Yamazaki, K1
Fujii, H; Hirose, C; Hishida, S; Iihara, H; Kiyama, S; Kobayashi, R; Makiyama, A; Matsuhashi, N; Matsuoka, S; Ohata, K; Suzuki, A; Tajima, JY; Takahashi, T; Watanabe, D1
Grothey, A; Kasi, PM1
Argilés, G; Baba, H; Benedetti, F; Cleary, JM; Esaki, T; Falcone, A; Garcia-Carbonero, R; Hamada, C; Hochster, HS; Komatsu, Y; Lenz, HJ; Makris, L; Mayer, RJ; Moriwaki, T; Muro, K; Nishina, T; Ohtsu, A; Peeters, M; Shimada, Y; Shinozaki, E; Sobrero, A; Sugimoto, N; Tanase, T; Tran, B; Tsuji, A; Tsuji, Y; Van Cutsem, E; Yamaguchi, K; Yamashita, F; Yamazaki, K; Yoshino, T; Zaniboni, A1
Colloca, G; Guarneri, D; Venturino, A1
Lenz, HJ; Yoshino, T1
Hata, T; Kagawa, Y; Kato, T; Katsura, Y; Kawai, K; Masuzawa, T; Mori, R; Murakami, K; Murata, K; Naito, A; Nose, Y; Ohmura, Y; Sakamoto, T; Takeda, Y; Takeno, A1
Imai, H; Ishioka, C; Kato, S; Komine, K; Kuroki, M; Ohori, H; Otsuka, K; Ouchi, K; Sakamoto, Y; Shibata, H; Shimodaira, H; Shirota, H; Takahashi, M; Takahashi, S; Takahashi, Y; Tanaka, M; Tsuji, Y; Yamaguchi, H; Yamaguchi, T; Yoshioka, T1
Carmona-Bayonas, A; Carriles Fernández, C; Cousillas Castiñeiras, A; Covela Rúa, M; De la Cámara Gómez, J; Fernández Montes, A; Garcia García, T; Gonzalez Villarroel, P; Jimenez-Fonseca, P; Martinez Lago, N; Méndez, JCM; Sanchez Cánovas, M; Vázquez Rivera, F1
Baars, A; Beerepoot, LV; Boot, H; Creemers, GJ; de Groot, JW; Hamberg, P; Jansen, RL; Kapiteijn, E; Koopman, M; Kwakman, JJM; Los, M; Opdam, FL; Punt, CJA; Schut, H; Sommeijer, DW; van Meerten, E; van Rooijen, JM; Vestjens, JH; Vink, G; Vulink, AJE1
Iwai, M; Kimura, M; Teramachi, H; Usami, E; Yoshimura, T1
Ikeda, Y; Iwai, M; Kawachi, S; Kimura, M; Mitsuoka, M; Usami, E; Yasue, F; Yoshimura, T1
Aisu, N; Daibo, K; Hasegawa, S; Kajitani, R; Kiyomi, F; Komono, A; Matsumoto, Y; Munechika, T; Sakamoto, R; Yoshida, Y1
Kimura, M; Teramachi, H; Usami, E; Yoshimura, T1
Bonetti, A; Giuliani, J1
Bando, H; Doi, T; Fuse, N; Goto, K; Ito, Y; Kojima, T; Mukai, H; Naito, Y; Ohtsu, A; Yamazaki, T; Yoshino, T1
Asano, H; Go, M; Ito, D; Iwai, M; Kimura, M; Teramachi, H; Usami, E; Yoshimura, T1
Aoyama, T; Hama, T; Inoue, A; Kawakami, K; Machida, Y; Suenaga, M; Sugisaki, T; Sugita, K; Suzuki, K; Takiguchi, T; Yamaguchi, K; Yamaguchi, T; Yokokawa, T1
Ando, M; Fukutomi, A; Hamauchi, S; Ishihara, M; Kadowaki, S; Kito, Y; Komori, A; Machida, N; Masuishi, T; Mori, K; Muro, K; Narita, Y; Onozawa, Y; Tajika, M; Tanaka, T; Taniguchi, H; Todaka, A; Tsushima, T; Ura, T; Yamazaki, K; Yasui, H; Yokota, T1

Trials

4 trial(s) available for trifluridine and Neutropenia

ArticleYear
Pooled safety analysis from phase III studies of trifluridine/tipiracil in patients with metastatic gastric or gastroesophageal junction cancer and metastatic colorectal cancer.
    ESMO open, 2022, Volume: 7, Issue:6

    Topics: Adult; Colonic Neoplasms; Colorectal Neoplasms; Esophagogastric Junction; Frontotemporal Dementia; Humans; Neutropenia; Pyrrolidines; Stomach Neoplasms; Thymine; Trifluridine; Uracil

2022
Neutropenia and survival outcomes in metastatic colorectal cancer patients treated with trifluridine/tipiracil in the RECOURSE and J003 trials.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2020, Volume: 31, Issue:1

    Topics: Colorectal Neoplasms; Drug Combinations; Humans; Japan; Neutropenia; Pyrrolidines; Thymine; Trifluridine; Uracil

2020
Phase II study of trifluridine/tipiracil (TAS-102) therapy in elderly patients with colorectal cancer (T-CORE1401): geriatric assessment tools and plasma drug concentrations as possible predictive biomarkers.
    Cancer chemotherapy and pharmacology, 2021, Volume: 88, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Colorectal Neoplasms; Drug Combinations; Drug Monitoring; Female; Geriatric Assessment; Humans; Male; Neutropenia; Progression-Free Survival; Pyrrolidines; Survival Rate; Thymine; Trifluridine

2021
Effect of food on the pharmacokinetics of TAS-102 and its efficacy and safety in patients with advanced solid tumors.
    Cancer science, 2016, Volume: 107, Issue:5

    Topics: Aged; Anemia; Antineoplastic Agents; Area Under Curve; Asian People; Biological Availability; Cross-Over Studies; Drug Combinations; Fasting; Female; Food-Drug Interactions; Humans; Japan; Leukopenia; Male; Middle Aged; Nausea; Neoplasms; Neutropenia; Pyrrolidines; Thymine; Trifluridine; Uracil

2016

Other Studies

17 other study(ies) available for trifluridine and Neutropenia

ArticleYear
Analysis of neutropenia as a predictive factor of the efficacy of trifluridine-tipiracil treatment.
    International journal of clinical pharmacology and therapeutics, 2023, Volume: 61, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Drug Combinations; Humans; Middle Aged; Neutropenia; Prospective Studies; Pyrrolidines; Retrospective Studies; Trifluridine

2023
Renal impairment as a risk factor for trifluridine/tipiracil-induced adverse events in metastatic colorectal cancer patients from the REGOTAS study.
    Scientific reports, 2023, 10-20, Volume: 13, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Drug Combinations; Frontotemporal Dementia; Humans; Neutropenia; Pyrrolidines; Rectal Neoplasms; Retrospective Studies; Risk Factors; Thymine; Trifluridine; Uracil

2023
Prognostic impact of severe neutropenia in colorectal cancer patients treated with TAS-102 and bevacizumab, addressing immortal-time bias.
    BMC cancer, 2023, Nov-08, Volume: 23, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Drug Combinations; Humans; Neutropenia; Prognosis; Retrospective Studies; Trifluridine; Uracil

2023
Should we optimize cytotoxic therapy by dosing to neutropenia? Lessons from TAS-102.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2020, Volume: 31, Issue:1

    Topics: Colorectal Neoplasms; Drug Combinations; Humans; Neutropenia; Pyrrolidines; Thymine; Trifluridine; Uracil

2020
Neutropenia in metastatic colorectal cancer receiving trifluridine/tipiracil.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2020, Volume: 31, Issue:7

    Topics: Colorectal Neoplasms; Humans; Neutropenia; Pyrrolidines; Thymine; Trifluridine

2020
Reply to the letter to the editor 'Neutropenia in metastatic colorectal cancer receiving trifluridine/tipiracil' by Colloca et al.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2020, Volume: 31, Issue:8

    Topics: Colorectal Neoplasms; Humans; Neutropenia; Pyrrolidines; Thymine; Trifluridine

2020
Neutropenia is an indicator of outcomes in metastatic colorectal cancer patients treated with FTD/TPI plus bevacizumab: a retrospective study.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Prognosis; Pyrrolidines; Retrospective Studies; Survival Rate; Thymine; Trifluridine

2020
Prediction of survival in patients with advanced, refractory colorectal cancer in treatment with trifluridine/tipiracil: real-world vs clinical trial data.
    Scientific reports, 2021, 07-12, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthenia; Colorectal Neoplasms; Drug Combinations; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Neutropenia; Pyrrolidines; Thymine; Trifluridine; Young Adult

2021
Feasibility and effectiveness of trifluridine/tipiracil in metastatic colorectal cancer: real-life data from The Netherlands.
    International journal of clinical oncology, 2018, Volume: 23, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Female; Humans; Leukopenia; Male; Middle Aged; Netherlands; Neutropenia; Prognosis; Pyrrolidines; Thymine; Treatment Outcome; Trifluridine; Uracil

2018
Severe neutropenia: a prognosticator in patients with advanced/recurrent colorectal cancer
    Die Pharmazie, 2017, Jan-10, Volume: 72, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Colorectal Neoplasms; Drug Combinations; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Prognosis; Pyrrolidines; Risk Factors; Survival Analysis; Thymine; Trifluridine; Uracil

2017
Risk factors contributing to the development of neutropenia in patients receiving oral trifluridine-tipiracil (TAS-102) chemotherapy for advanced/recurrent colorectal cancer.
    Die Pharmazie, 2018, 03-05, Volume: 73, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Creatinine; Drug Combinations; Female; Humans; Leukocyte Count; Male; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Neutrophils; Pyrrolidines; Retrospective Studies; Risk Factors; Thymine; Trifluridine; Uracil

2018
Biweekly Administration of TAS-102 for Neutropenia Prevention in Patients with Colorectal Cancer.
    Anticancer research, 2018, Volume: 38, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Female; Humans; Male; Middle Aged; Neutropenia; Pyrrolidines; Retrospective Studies; Thymine; Trifluridine; Uracil

2018
Evaluation of Tolerability of Trifluridine/Tipiracil Combination Tablet in Patients With Advanced/Recurrent Colorectal Cancer.
    Anticancer research, 2019, Volume: 39, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Female; Humans; Male; Middle Aged; Nausea; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neutropenia; Pyrrolidines; Retrospective Studies; Tablets; Thymine; Treatment Outcome; Trifluridine; Uracil

2019
The Onset of Grade ≥3 Neutropenia Is Associated With Longer Overall Survival in Metastatic Colorectal Cancer Patients Treated With Trifluridine/Tipiracil.
    Anticancer research, 2019, Volume: 39, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Colorectal Neoplasms; Drug Combinations; Female; Humans; Male; Middle Aged; Neutropenia; Pyrrolidines; Survival Analysis; Thymine; Trifluridine; Uracil

2019
Safety of an oral anticancer agent (trifluridine/tipiracil combination tablet) in patients with advanced and recurrent colorectal cancer.
    Die Pharmazie, 2016, Volume: 71, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Drug Combinations; Female; Humans; Male; Middle Aged; Nausea; Neoplasm Recurrence, Local; Neutropenia; Patient Safety; Pyrrolidines; Retrospective Studies; Tablets; Thymine; Trifluridine; Uracil; Vomiting

2016
Self-Reported Adherence to Trifluridine and Tipiracil Hydrochloride for Metastatic Colorectal Cancer: A Retrospective Cohort Study.
    Oncology, 2016, Volume: 91, Issue:4

    Topics: Abdominal Pain; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Appetite; Colorectal Neoplasms; Female; Humans; Male; Medication Adherence; Middle Aged; Nausea; Neutropenia; Pyrrolidines; Retrospective Studies; Self Report; Thymine; Trifluridine; Vomiting

2016
Neutropenia as a Predictive Factor in Metastatic Colorectal Cancer Treated With TAS-102.
    Clinical colorectal cancer, 2017, Volume: 16, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colorectal Neoplasms; Drug Combinations; Female; Humans; Male; Middle Aged; Neutropenia; Prognosis; Pyrrolidines; Retrospective Studies; Thymine; Trifluridine; Uracil

2017