trifluralin has been researched along with American Trypanosomiasis in 5 studies
Trifluralin: A microtubule-disrupting pre-emergence herbicide.
trifluralin : A substituted aniline that is N,N-dipropylaniline substituted by a nitro groups at positions 2 and 6 and a trifluoromethyl group at position 4. It is an agrochemical used as a pre-emergence herbicide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Even though trifluralin (alpha,alpha,alpha-2,6-dinitro-N-N-dipropyl-p-toluidine) is effective for the treatment of experimental Chagas disease, more preclinical toxicity studies need to be performed." | 7.74 | Trifluralin toxicity in a Chagas disease mouse model. ( Drut, R; Gómez, P; Luong, T; Marra, C; Milani, L; Villagra, S; Zaidenberg, A, 2007) |
| "We tested trifluralin against Trypanosoma cruzi in a model of chronic Chagas disease in mice." | 7.73 | Treatment of experimental chronic chagas disease with trifluralin. ( Bleiz, J; Buschiazzo, H; Del Buono, MB; Drut, R; Kozubsky, L; Lirussi, D; Luong, T; Marron, A; Quijano, G; Zaidenberg, A, 2006) |
| "Trifluralin displays anti-Trypanosoma cruzi activity and a potential therapeutic effect for the treatment of Chagas disease." | 3.75 | Pharmacokinetics of trifluralin in blood and heart tissue of mice. ( Marra, C; Rule, R; Villagra, S; Zaidenberg, A, 2009) |
| "Even though trifluralin (alpha,alpha,alpha-2,6-dinitro-N-N-dipropyl-p-toluidine) is effective for the treatment of experimental Chagas disease, more preclinical toxicity studies need to be performed." | 3.74 | Trifluralin toxicity in a Chagas disease mouse model. ( Drut, R; Gómez, P; Luong, T; Marra, C; Milani, L; Villagra, S; Zaidenberg, A, 2007) |
| "We tested trifluralin against Trypanosoma cruzi in a model of chronic Chagas disease in mice." | 3.73 | Treatment of experimental chronic chagas disease with trifluralin. ( Bleiz, J; Buschiazzo, H; Del Buono, MB; Drut, R; Kozubsky, L; Lirussi, D; Luong, T; Marron, A; Quijano, G; Zaidenberg, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zaidenberg, A | 4 |
| Marra, C | 2 |
| Villagra, S | 2 |
| Rule, R | 1 |
| Luong, T | 2 |
| Lirussi, D | 1 |
| Bleiz, J | 1 |
| Del Buono, MB | 1 |
| Quijano, G | 1 |
| Drut, R | 2 |
| Kozubsky, L | 1 |
| Marron, A | 1 |
| Buschiazzo, H | 2 |
| Gómez, P | 1 |
| Milani, L | 1 |
| Traub-Cseko, YM | 1 |
| Ramalho-Ortigão, JM | 1 |
| Dantas, AP | 1 |
| de Castro, SL | 1 |
| Barbosa, HS | 1 |
| Downing, KH | 1 |
| Marra, CA | 1 |
| de Alaniz, MJ | 1 |
1 review available for trifluralin and American Trypanosomiasis
| Article | Year |
|---|---|
Dinitroaniline herbicides against protozoan parasites: the case of Trypanosoma cruzi.
Topics: Amino Acid Sequence; Aniline Compounds; Animals; Chagas Disease; Herbicides; Humans; Molecular Seque | 2001 |
4 other studies available for trifluralin and American Trypanosomiasis
| Article | Year |
|---|---|
Pharmacokinetics of trifluralin in blood and heart tissue of mice.
Topics: Adipose Tissue; Animals; Chagas Cardiomyopathy; Chagas Disease; Feces; Humans; Liver; Male; Mice; My | 2009 |
Treatment of experimental chronic chagas disease with trifluralin.
Topics: Animals; Chagas Disease; Disease Models, Animal; Electrocardiography; Heart; Herbicides; Male; Mice; | 2006 |
Trifluralin toxicity in a Chagas disease mouse model.
Topics: Animals; Body Weight; Chagas Disease; Chlorocebus aethiops; Disease Models, Animal; Dose-Response Re | 2007 |
The restoring effect of trifluralin and benznidazole on the abnormal fatty-acid pattern induced by Trypanosoma cruzi in the liver microsomes of infected mice.
Topics: Animals; Chagas Disease; Cholesterol; Cholesterol Esters; Fatty Acids; Male; Mice; Mice, Inbred Stra | 2002 |