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trifluoroacetic acid and Chemical and Drug Induced Liver Injury

trifluoroacetic acid has been researched along with Chemical and Drug Induced Liver Injury in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19908 (24.24)18.7374
1990's17 (51.52)18.2507
2000's7 (21.21)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barat, N; Li, Z; Mellerson, JL; Njoku, DB; Rose, NR; Sharma, R; Talor, MV1
Li, Z; Mellerson, JL; Njoku, DB; Rose, NR; Sharma, R; Talor, MV; Washington, ND1
Cheng, L; Ju, C; You, Q1
Bortolato, S; Brotto, M; Gervasi, PG; Manno, M; Marini, S; Rugge, M; Zanovello, A1
Albores, A; Dekant, W; García-Latorre, EA; Manno, M; Oropeza-Hernández, LF; Quintanilla-Vega, B; Reyes-Mejía, RA; Serrano, CJ1
Fairweather, D; Frisancho-Kiss, S; Njoku, DB; Odumade, OA; Rose, NR; Talor, MV1
Cheng, L; Ju, C; Reilly, TP; Wegmann, D; You, Q1
Lin, WQ; Marsh, HM; Trudell, JR; van Dyke, RA1
Amouzadeh, HR; Pohl, LR1
Christen, U; Frey, N; Gut, J; Koch, V; Stoffler, D1
Inaba, S; Irita, K; Nawata, H; Sakaguchi, Y; Sakai, H; Takahashi, S1
Guillouzo, A; Ilyin, GP; Malledant, Y; Rissel, M; Tanguy, M1
Kenna, JG; Knight, TL; van Pelt, FN1
Kenna, JG; Martin, BM; Martin, JL; Pohl, LR; Reed, GF; Thomassen, D1
Furst, SM; Gandolfi, AJ; Gaw, HH; Luedke, D; Reich, R1
Bourdi, M; Chen, W; Duray, PH; Graf, ML; Hoet, P; Lison, D; Nelson, SD; Peter, RM; Pohl, LR; Verlinden, N1
Abu-Asab, MS; Duray, PR; Njoku, DB; Pohl, LR; Shrestha, S; Soloway, R; Tsokos, M; West, AB1
Cohen, EN; Edmunds, HN; Trudell, JR; Watson, E1
Dumonde, DC; Hamblin, A; Simpson, R; Walton, B1
McCracken, LE; Reves, JG1
Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M1
Bürgin, M; Christen, U; Gut, J; Huwyler, J; Kenna, JG1
Gandolfi, AJ; Hubbard, AK; Levy, JP; Roth, TP1
Gandolfi, AJ; Hastings, KL; Hubbard, AK; Thomas, C1
Fujii, K; Kinoshita, H; Morio, M; Nakao, M; Yuge, O1
Anderson, WR; Ardies, CM; Trudell, JR1
Butler, LE; Ferrans, VJ; Martin, BM; Martin, JL; Perrone, A; Pohl, LR; Pumford, NR; Satoh, H; Thomassen, D1
Brown, AP; Gandolfi, AJ; Hastings, KL; Schuman, S; Thomas, C1
Christ, D; Kenna, JG; Martin, JL; Pohl, LR; Satoh, H1
Christ, DD; Kenna, JG; Martin, BM; Pohl, LR; Satoh, H; Schulick, AH1
Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC1
Gandolfi, AJ; Hubbard, AK; Roth, TP; Siadat-Pajouh, M1
Brown, BR; Gandolfi, AJ; Lind, RC; Sipes, IG1

Reviews

3 review(s) available for trifluoroacetic acid and Chemical and Drug Induced Liver Injury

ArticleYear
Molecular mimicry in halothane hepatitis: biochemical and structural characterization of lipoylated autoantigens.
    Toxicology, 1995, Mar-31, Volume: 97, Issue:1-3

    Topics: Autoantigens; Chemical and Drug Induced Liver Injury; Cross Reactions; Halothane; Humans; Liver Cirrhosis, Biliary; Thioctic Acid; Trifluoroacetic Acid

1995
Hapten carrier conjugates associated with halothane hepatitis.
    Advances in experimental medicine and biology, 1991, Volume: 283

    Topics: Animals; Carrier Proteins; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Halothane; Haptens; Humans; Microsomes, Liver; Rats; Trifluoroacetic Acid

1991
Neoantigens associated with halothane hepatitis.
    Drug metabolism reviews, 1989, Volume: 20, Issue:2-4

    Topics: Animals; Antigens; Carrier Proteins; Chemical and Drug Induced Liver Injury; Halothane; Humans; Trifluoroacetic Acid

1989

Other Studies

30 other study(ies) available for trifluoroacetic acid and Chemical and Drug Induced Liver Injury

ArticleYear
IP-10 protects while MIP-2 promotes experimental anesthetic hapten - induced hepatitis.
    Journal of autoimmunity, 2009, Volume: 32, Issue:1

    Topics: Anesthetics; Animals; Antibodies; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Chemical and Drug Induced Liver Injury; Chemokine CXCL10; Chemokine CXCL2; Chemokine CXCL9; Cytochrome P-450 CYP2E1; Female; Haptens; Interleukin-4; Liver; Mice; Mice, Inbred BALB C; Mice, Knockout; Models, Immunological; Neutrophils; Receptors, CXCR3; Receptors, Interleukin-8B; Spleen; T-Lymphocytes; Trifluoroacetic Acid

2009
Suppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury.
    European journal of immunology, 2009, Volume: 39, Issue:6

    Topics: Adoptive Transfer; Animals; Antibodies; CD4-Positive T-Lymphocytes; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytokines; Disease Models, Animal; Female; Fluoroacetates; Homeodomain Proteins; Interleukin-10; Interleukin-4; Killer Cells, Natural; Liver; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Knockout; Models, Immunological; Natural Killer T-Cells; S100 Proteins; Spleen; T-Lymphocytes; T-Lymphocytes, Regulatory; Th1 Cells; Th2 Cells; Trifluoroacetic Acid

2009
Generation of T cell responses targeting the reactive metabolite of halothane in mice.
    Toxicology letters, 2010, May-04, Volume: 194, Issue:3

    Topics: Animals; CD40 Antigens; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Halothane; Mice; Mice, Inbred Strains; T-Lymphocytes; Toll-Like Receptors; Trifluoroacetic Acid

2010
Trifluoroacetylated proteins in liver and plasma of guinea pigs treated with HCFC-123 and halothane.
    Toxicology letters, 2003, Sep-15, Volume: 144, Issue:1

    Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Azo Compounds; Biomarkers; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Coloring Agents; Creatine Kinase; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; Halothane; Immunoblotting; Liver; Male; Proteins; Trifluoroacetic Acid

2003
Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane.
    Toxicology letters, 2003, Sep-15, Volume: 144, Issue:1

    Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Biomarkers; Body Weight; Chemical and Drug Induced Liver Injury; Chromatin; Cytochrome P-450 CYP2E1; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Halothane; Immunohistochemistry; Indicators and Reagents; Liver; Male; Microsomes, Liver; Pyridines; Rats; Rats, Wistar; Spermatozoa; Testis; Trifluoroacetic Acid

2003
A novel model of drug hapten-induced hepatitis with increased mast cells in the BALB/c mouse.
    Experimental and molecular pathology, 2005, Volume: 78, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Autoantibodies; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; Fluoroacetates; Haptens; Hepatitis, Autoimmune; Liver; Mast Cells; Mice; Mice, Inbred BALB C; S100 Proteins; Trifluoroacetic Acid

2005
Role of neutrophils in a mouse model of halothane-induced liver injury.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:6

    Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Fluoroacetates; Halothane; Kupffer Cells; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neutrophils; Proteins; Trifluoroacetic Acid

2006
Time course of 72-kilodalton heat shock protein induction and appearance of trifluoroacetyl adducts in livers of halothane-exposed rats.
    Molecular pharmacology, 1994, Volume: 46, Issue:4

    Topics: Animals; Blotting, Western; Chemical and Drug Induced Liver Injury; Electrophoresis, Polyacrylamide Gel; Halothane; Heat-Shock Proteins; Indicators and Reagents; Kinetics; Liver; Male; Rats; Rats, Sprague-Dawley; Rosaniline Dyes; Staining and Labeling; Trifluoroacetic Acid

1994
Processing of endoplasmic reticulum luminal antigens associated with halothane hepatitis in rat hepatocytes.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:3

    Topics: Animals; Antigens; Carrier Proteins; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Female; Half-Life; Halothane; Haptens; Liver; Proteins; Rats; Rats, Sprague-Dawley; Trifluoroacetic Acid

1995
Absence of anti-trifluoroacetate antibody after halothane anaesthesia in patients exhibiting no or mild liver damage.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:5 Pt 1

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Anesthesia, Inhalation; Animals; Antibodies; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Electrophoresis, Polyacrylamide Gel; Female; Halothane; Humans; Immunoblotting; Infant; Liver Failure; Male; Middle Aged; Rabbits; Rats; Rats, Wistar; Serum Albumin; Trifluoroacetic Acid

1994
Human hepatocytes express trifluoroacetylated neoantigens after in vitro exposure to halothane.
    Biochemical pharmacology, 1994, Aug-03, Volume: 48, Issue:3

    Topics: Antibody Specificity; Antigens; Biotransformation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Fluoroacetates; Halothane; Humans; Liver; Serum Albumin; Trifluoroacetic Acid

1994
Immunity to halothane metabolite-modified proteins in halothane hepatitis.
    Annals of the New York Academy of Sciences, 1993, Jun-23, Volume: 685

    Topics: Animals; Antibody Formation; Antigens; Biotransformation; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Immunoblotting; Liver; Male; Rabbits; Rats; Rats, Sprague-Dawley; Trifluoroacetic Acid

1993
Halothane hepatitis patients have serum antibodies that react with protein disulfide isomerase.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:4

    Topics: Antibodies; Antigens; Chemical and Drug Induced Liver Injury; Halothane; Humans; Isomerases; Microsomes, Liver; Molecular Weight; Protein Disulfide-Isomerases; Trifluoroacetic Acid

1993
Demonstration of a cellular immune response in halothane-exposed guinea pigs.
    Toxicology and applied pharmacology, 1997, Volume: 143, Issue:2

    Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Antigen-Presenting Cells; Cell Division; Cells, Cultured; Chemical and Drug Induced Liver Injury; Coculture Techniques; Fluoroacetates; Guinea Pigs; Halothane; Immunity, Cellular; Kupffer Cells; Lymphocyte Activation; Lymphocytes; Male; Spleen; Trifluoroacetic Acid

1997
Epidemic of liver disease caused by hydrochlorofluorocarbons used as ozone-sparing substitutes of chlorofluorocarbons.
    Lancet (London, England), 1997, Aug-23, Volume: 350, Issue:9077

    Topics: Biomarkers; Biopsy; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Chlorofluorocarbons, Methane; Cytochrome P-450 CYP2E1; Disease Outbreaks; Humans; Immunohistochemistry; Male; Middle Aged; Occupational Exposure; Trifluoroacetic Acid

1997
Subcellular localization of trifluoroacetylated liver proteins in association with hepatitis following isoflurane.
    Anesthesiology, 2002, Volume: 96, Issue:3

    Topics: Aged; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Endarterectomy, Carotid; Humans; Immunohistochemistry; Isoflurane; Liver; Liver Function Tests; Male; Microscopy, Electron; Proteins; Subcellular Fractions; Transaminases; Trifluoroacetic Acid

2002
Urinary metabolites of halothane in man.
    Anesthesiology, 1975, Volume: 43, Issue:4

    Topics: Binding Sites; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cysteine; Ethanolamines; Fluoroacetates; Glutathione; Halothane; Heart Transplantation; Humans; Liver; Tissue Donors; Transplantation, Homologous; Trifluoroacetic Acid

1975
Absence of cellular hypersensitivity in patients with unexplained hepatitis following halothane.
    Anesthesiology, 1976, Volume: 44, Issue:5

    Topics: Anesthesia, Inhalation; Cell Migration Inhibition; Chemical and Drug Induced Liver Injury; Halothane; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Leukocytes; Liver; Lymphocyte Activation; Lymphocytes; Proteins; Serum Albumin; Trifluoroacetic Acid

1976
Hepatic pathology and skin test reactions to trifluoro-acetylated autologous protein after repeated halothane anaesthesia in the guineapig.
    British journal of anaesthesia, 1976, Volume: 48, Issue:5

    Topics: Anesthesia, General; Animals; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Fluoroacetates; Guinea Pigs; Halothane; Liver; Serum Albumin; Skin Tests; Trifluoroacetic Acid

1976
Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol.
    Biochemical pharmacology, 1992, Nov-03, Volume: 44, Issue:9

    Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Cytosol; Ethanol; Kinetics; Lethal Dose 50; Liver; Liver Diseases; Male; Microsomes, Liver; Mitochondria, Liver; NAD; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Wistar; Sensitivity and Specificity; Subcellular Fractions; Trifluoroacetic Acid; Trifluoroethanol

1992
Molecular mimicry of trifluoroacetylated human liver protein adducts by constitutive proteins and immunochemical evidence for its impairment in halothane hepatitis.
    European journal of biochemistry, 1992, Dec-01, Volume: 210, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Animals; Biopsy; Chemical and Drug Induced Liver Injury; Child, Preschool; Female; Fluoroacetates; Halothane; Humans; Immunoblotting; Immunohistochemistry; Liver; Male; Middle Aged; Molecular Weight; Proteins; Rats; Rats, Sprague-Dawley; Trifluoroacetic Acid

1992
Use of structural alterations in the synthesis of halothane metabolite antigens to mimic halothane-induced immunogen.
    Drug and chemical toxicology, 1990, Volume: 13, Issue:2-3

    Topics: Acetates; Acetylation; Aminocaproates; Animals; Antibodies; Chemical and Drug Induced Liver Injury; Epitopes; Female; Fluorine; Fluoroacetates; Halothane; Haptens; Humans; Immunoblotting; Rabbits; Serum Albumin; Trifluoroacetic Acid; Vaccines, Synthetic

1990
Screening for antibodies associated with halothane hepatitis.
    British journal of anaesthesia, 1991, Volume: 67, Issue:6

    Topics: Animals; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Fluoroacetates; Halothane; Hepatitis Antibodies; Humans; Infant; Lysine; Male; Microsomes, Liver; Rabbits; Serum Albumin; Trifluoroacetic Acid

1991
Aerobic dehalogenation of halothane showing different substrate dependency from anaerobic dehalogenation in liver microsomes of guinea pig.
    Hiroshima journal of medical sciences, 1991, Volume: 40, Issue:1

    Topics: Aerobiosis; Animals; Chemical and Drug Induced Liver Injury; Guinea Pigs; Halothane; In Vitro Techniques; Male; Microsomes, Liver; Trifluoroacetic Acid

1991
The effect of alcohol and anesthetic metabolites on cell membranes. A possible direct immune mechanism.
    Annals of the New York Academy of Sciences, 1991, Volume: 625

    Topics: Acetaldehyde; Alcoholism; Animals; Antibody Formation; Cell Membrane; Chemical and Drug Induced Liver Injury; Ethanol; Flow Cytometry; Halothane; Haptens; Humans; Immunoglobulin G; Lipid Bilayers; Liver; Liver Diseases; Molecular Conformation; Phosphatidylethanolamines; Rabbits; Trifluoroacetic Acid

1991
S-ethylthiotrifluoroacetate enhancement of the immune response to halothane in the guinea pig.
    Advances in experimental medicine and biology, 1991, Volume: 283

    Topics: Animals; Antibody Formation; Antigens; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Fluoroacetates; Guinea Pigs; Halothane; Male; Proteins; Trifluoroacetic Acid

1991
Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:1

    Topics: Animals; Antibodies; Carboxylesterase; Carboxylic Ester Hydrolases; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Fluoroacetates; Halothane; Humans; Male; Microsomes, Liver; Molecular Weight; Protein Binding; Rats; Rats, Inbred Strains; Trifluoroacetic Acid

1989
Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat.
    Toxicology, 1988, Volume: 50, Issue:1

    Topics: Administration, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Halothane; Hydrocarbons, Halogenated; Hyperthyroidism; Liver Diseases; Male; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Trifluoroacetic Acid; Triiodothyronine

1988
Generation of halothane-induced immune response in a guinea pig model of halothane hepatitis.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:12

    Topics: Animals; Antibody Formation; Antigens; Chemical and Drug Induced Liver Injury; Female; Guinea Pigs; Halothane; Male; Serum Albumin; Species Specificity; Trifluoroacetic Acid

1987
Comparison of the requirements for hepatic injury with halothane and enflurane in rats.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:10

    Topics: Anesthesia, Inhalation; Animals; Biotransformation; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enflurane; Fluorides; Halothane; Hot Temperature; Hypoxia; Liver; Male; Models, Biological; Oxygen; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Trifluoroacetic Acid

1985