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trifluoroacetic acid and Acute Liver Injury, Drug-Induced

trifluoroacetic acid has been researched along with Acute Liver Injury, Drug-Induced in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19908 (24.24)18.7374
1990's17 (51.52)18.2507
2000's7 (21.21)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barat, N; Li, Z; Mellerson, JL; Njoku, DB; Rose, NR; Sharma, R; Talor, MV1
Li, Z; Mellerson, JL; Njoku, DB; Rose, NR; Sharma, R; Talor, MV; Washington, ND1
Cheng, L; Ju, C; You, Q1
Bortolato, S; Brotto, M; Gervasi, PG; Manno, M; Marini, S; Rugge, M; Zanovello, A1
Albores, A; Dekant, W; García-Latorre, EA; Manno, M; Oropeza-Hernández, LF; Quintanilla-Vega, B; Reyes-Mejía, RA; Serrano, CJ1
Fairweather, D; Frisancho-Kiss, S; Njoku, DB; Odumade, OA; Rose, NR; Talor, MV1
Cheng, L; Ju, C; Reilly, TP; Wegmann, D; You, Q1
Lin, WQ; Marsh, HM; Trudell, JR; van Dyke, RA1
Amouzadeh, HR; Pohl, LR1
Christen, U; Frey, N; Gut, J; Koch, V; Stoffler, D1
Inaba, S; Irita, K; Nawata, H; Sakaguchi, Y; Sakai, H; Takahashi, S1
Guillouzo, A; Ilyin, GP; Malledant, Y; Rissel, M; Tanguy, M1
Kenna, JG; Knight, TL; van Pelt, FN1
Kenna, JG; Martin, BM; Martin, JL; Pohl, LR; Reed, GF; Thomassen, D1
Furst, SM; Gandolfi, AJ; Gaw, HH; Luedke, D; Reich, R1
Bourdi, M; Chen, W; Duray, PH; Graf, ML; Hoet, P; Lison, D; Nelson, SD; Peter, RM; Pohl, LR; Verlinden, N1
Abu-Asab, MS; Duray, PR; Njoku, DB; Pohl, LR; Shrestha, S; Soloway, R; Tsokos, M; West, AB1
Cohen, EN; Edmunds, HN; Trudell, JR; Watson, E1
Dumonde, DC; Hamblin, A; Simpson, R; Walton, B1
McCracken, LE; Reves, JG1
Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M1
Bürgin, M; Christen, U; Gut, J; Huwyler, J; Kenna, JG1
Gandolfi, AJ; Hubbard, AK; Levy, JP; Roth, TP1
Gandolfi, AJ; Hastings, KL; Hubbard, AK; Thomas, C1
Fujii, K; Kinoshita, H; Morio, M; Nakao, M; Yuge, O1
Anderson, WR; Ardies, CM; Trudell, JR1
Butler, LE; Ferrans, VJ; Martin, BM; Martin, JL; Perrone, A; Pohl, LR; Pumford, NR; Satoh, H; Thomassen, D1
Brown, AP; Gandolfi, AJ; Hastings, KL; Schuman, S; Thomas, C1
Christ, D; Kenna, JG; Martin, JL; Pohl, LR; Satoh, H1
Christ, DD; Kenna, JG; Martin, BM; Pohl, LR; Satoh, H; Schulick, AH1
Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC1
Gandolfi, AJ; Hubbard, AK; Roth, TP; Siadat-Pajouh, M1
Brown, BR; Gandolfi, AJ; Lind, RC; Sipes, IG1

Reviews

3 review(s) available for trifluoroacetic acid and Acute Liver Injury, Drug-Induced

ArticleYear
Molecular mimicry in halothane hepatitis: biochemical and structural characterization of lipoylated autoantigens.
    Toxicology, 1995, Mar-31, Volume: 97, Issue:1-3

    Topics: Autoantigens; Chemical and Drug Induced Liver Injury; Cross Reactions; Halothane; Humans; Liver Cirrhosis, Biliary; Thioctic Acid; Trifluoroacetic Acid

1995
Hapten carrier conjugates associated with halothane hepatitis.
    Advances in experimental medicine and biology, 1991, Volume: 283

    Topics: Animals; Carrier Proteins; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Halothane; Haptens; Humans; Microsomes, Liver; Rats; Trifluoroacetic Acid

1991
Neoantigens associated with halothane hepatitis.
    Drug metabolism reviews, 1989, Volume: 20, Issue:2-4

    Topics: Animals; Antigens; Carrier Proteins; Chemical and Drug Induced Liver Injury; Halothane; Humans; Trifluoroacetic Acid

1989

Other Studies

30 other study(ies) available for trifluoroacetic acid and Acute Liver Injury, Drug-Induced

ArticleYear
IP-10 protects while MIP-2 promotes experimental anesthetic hapten - induced hepatitis.
    Journal of autoimmunity, 2009, Volume: 32, Issue:1

    Topics: Anesthetics; Animals; Antibodies; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Chemical and Drug Induced Liver Injury; Chemokine CXCL10; Chemokine CXCL2; Chemokine CXCL9; Cytochrome P-450 CYP2E1; Female; Haptens; Interleukin-4; Liver; Mice; Mice, Inbred BALB C; Mice, Knockout; Models, Immunological; Neutrophils; Receptors, CXCR3; Receptors, Interleukin-8B; Spleen; T-Lymphocytes; Trifluoroacetic Acid

2009
Suppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury.
    European journal of immunology, 2009, Volume: 39, Issue:6

    Topics: Adoptive Transfer; Animals; Antibodies; CD4-Positive T-Lymphocytes; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytokines; Disease Models, Animal; Female; Fluoroacetates; Homeodomain Proteins; Interleukin-10; Interleukin-4; Killer Cells, Natural; Liver; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Knockout; Models, Immunological; Natural Killer T-Cells; S100 Proteins; Spleen; T-Lymphocytes; T-Lymphocytes, Regulatory; Th1 Cells; Th2 Cells; Trifluoroacetic Acid

2009
Generation of T cell responses targeting the reactive metabolite of halothane in mice.
    Toxicology letters, 2010, May-04, Volume: 194, Issue:3

    Topics: Animals; CD40 Antigens; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Halothane; Mice; Mice, Inbred Strains; T-Lymphocytes; Toll-Like Receptors; Trifluoroacetic Acid

2010
Trifluoroacetylated proteins in liver and plasma of guinea pigs treated with HCFC-123 and halothane.
    Toxicology letters, 2003, Sep-15, Volume: 144, Issue:1

    Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Azo Compounds; Biomarkers; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Coloring Agents; Creatine Kinase; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; Halothane; Immunoblotting; Liver; Male; Proteins; Trifluoroacetic Acid

2003
Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane.
    Toxicology letters, 2003, Sep-15, Volume: 144, Issue:1

    Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Biomarkers; Body Weight; Chemical and Drug Induced Liver Injury; Chromatin; Cytochrome P-450 CYP2E1; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Halothane; Immunohistochemistry; Indicators and Reagents; Liver; Male; Microsomes, Liver; Pyridines; Rats; Rats, Wistar; Spermatozoa; Testis; Trifluoroacetic Acid

2003
A novel model of drug hapten-induced hepatitis with increased mast cells in the BALB/c mouse.
    Experimental and molecular pathology, 2005, Volume: 78, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Autoantibodies; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; Fluoroacetates; Haptens; Hepatitis, Autoimmune; Liver; Mast Cells; Mice; Mice, Inbred BALB C; S100 Proteins; Trifluoroacetic Acid

2005
Role of neutrophils in a mouse model of halothane-induced liver injury.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:6

    Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Fluoroacetates; Halothane; Kupffer Cells; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neutrophils; Proteins; Trifluoroacetic Acid

2006
Time course of 72-kilodalton heat shock protein induction and appearance of trifluoroacetyl adducts in livers of halothane-exposed rats.
    Molecular pharmacology, 1994, Volume: 46, Issue:4

    Topics: Animals; Blotting, Western; Chemical and Drug Induced Liver Injury; Electrophoresis, Polyacrylamide Gel; Halothane; Heat-Shock Proteins; Indicators and Reagents; Kinetics; Liver; Male; Rats; Rats, Sprague-Dawley; Rosaniline Dyes; Staining and Labeling; Trifluoroacetic Acid

1994
Processing of endoplasmic reticulum luminal antigens associated with halothane hepatitis in rat hepatocytes.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:3

    Topics: Animals; Antigens; Carrier Proteins; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Female; Half-Life; Halothane; Haptens; Liver; Proteins; Rats; Rats, Sprague-Dawley; Trifluoroacetic Acid

1995
Absence of anti-trifluoroacetate antibody after halothane anaesthesia in patients exhibiting no or mild liver damage.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:5 Pt 1

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Anesthesia, Inhalation; Animals; Antibodies; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Electrophoresis, Polyacrylamide Gel; Female; Halothane; Humans; Immunoblotting; Infant; Liver Failure; Male; Middle Aged; Rabbits; Rats; Rats, Wistar; Serum Albumin; Trifluoroacetic Acid

1994
Human hepatocytes express trifluoroacetylated neoantigens after in vitro exposure to halothane.
    Biochemical pharmacology, 1994, Aug-03, Volume: 48, Issue:3

    Topics: Antibody Specificity; Antigens; Biotransformation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Fluoroacetates; Halothane; Humans; Liver; Serum Albumin; Trifluoroacetic Acid

1994
Immunity to halothane metabolite-modified proteins in halothane hepatitis.
    Annals of the New York Academy of Sciences, 1993, Jun-23, Volume: 685

    Topics: Animals; Antibody Formation; Antigens; Biotransformation; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Immunoblotting; Liver; Male; Rabbits; Rats; Rats, Sprague-Dawley; Trifluoroacetic Acid

1993
Halothane hepatitis patients have serum antibodies that react with protein disulfide isomerase.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:4

    Topics: Antibodies; Antigens; Chemical and Drug Induced Liver Injury; Halothane; Humans; Isomerases; Microsomes, Liver; Molecular Weight; Protein Disulfide-Isomerases; Trifluoroacetic Acid

1993
Demonstration of a cellular immune response in halothane-exposed guinea pigs.
    Toxicology and applied pharmacology, 1997, Volume: 143, Issue:2

    Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Antigen-Presenting Cells; Cell Division; Cells, Cultured; Chemical and Drug Induced Liver Injury; Coculture Techniques; Fluoroacetates; Guinea Pigs; Halothane; Immunity, Cellular; Kupffer Cells; Lymphocyte Activation; Lymphocytes; Male; Spleen; Trifluoroacetic Acid

1997
Epidemic of liver disease caused by hydrochlorofluorocarbons used as ozone-sparing substitutes of chlorofluorocarbons.
    Lancet (London, England), 1997, Aug-23, Volume: 350, Issue:9077

    Topics: Biomarkers; Biopsy; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Chlorofluorocarbons, Methane; Cytochrome P-450 CYP2E1; Disease Outbreaks; Humans; Immunohistochemistry; Male; Middle Aged; Occupational Exposure; Trifluoroacetic Acid

1997
Subcellular localization of trifluoroacetylated liver proteins in association with hepatitis following isoflurane.
    Anesthesiology, 2002, Volume: 96, Issue:3

    Topics: Aged; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Endarterectomy, Carotid; Humans; Immunohistochemistry; Isoflurane; Liver; Liver Function Tests; Male; Microscopy, Electron; Proteins; Subcellular Fractions; Transaminases; Trifluoroacetic Acid

2002
Urinary metabolites of halothane in man.
    Anesthesiology, 1975, Volume: 43, Issue:4

    Topics: Binding Sites; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cysteine; Ethanolamines; Fluoroacetates; Glutathione; Halothane; Heart Transplantation; Humans; Liver; Tissue Donors; Transplantation, Homologous; Trifluoroacetic Acid

1975
Absence of cellular hypersensitivity in patients with unexplained hepatitis following halothane.
    Anesthesiology, 1976, Volume: 44, Issue:5

    Topics: Anesthesia, Inhalation; Cell Migration Inhibition; Chemical and Drug Induced Liver Injury; Halothane; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Leukocytes; Liver; Lymphocyte Activation; Lymphocytes; Proteins; Serum Albumin; Trifluoroacetic Acid

1976
Hepatic pathology and skin test reactions to trifluoro-acetylated autologous protein after repeated halothane anaesthesia in the guineapig.
    British journal of anaesthesia, 1976, Volume: 48, Issue:5

    Topics: Anesthesia, General; Animals; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Fluoroacetates; Guinea Pigs; Halothane; Liver; Serum Albumin; Skin Tests; Trifluoroacetic Acid

1976
Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol.
    Biochemical pharmacology, 1992, Nov-03, Volume: 44, Issue:9

    Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Cytosol; Ethanol; Kinetics; Lethal Dose 50; Liver; Liver Diseases; Male; Microsomes, Liver; Mitochondria, Liver; NAD; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Wistar; Sensitivity and Specificity; Subcellular Fractions; Trifluoroacetic Acid; Trifluoroethanol

1992
Molecular mimicry of trifluoroacetylated human liver protein adducts by constitutive proteins and immunochemical evidence for its impairment in halothane hepatitis.
    European journal of biochemistry, 1992, Dec-01, Volume: 210, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Animals; Biopsy; Chemical and Drug Induced Liver Injury; Child, Preschool; Female; Fluoroacetates; Halothane; Humans; Immunoblotting; Immunohistochemistry; Liver; Male; Middle Aged; Molecular Weight; Proteins; Rats; Rats, Sprague-Dawley; Trifluoroacetic Acid

1992
Use of structural alterations in the synthesis of halothane metabolite antigens to mimic halothane-induced immunogen.
    Drug and chemical toxicology, 1990, Volume: 13, Issue:2-3

    Topics: Acetates; Acetylation; Aminocaproates; Animals; Antibodies; Chemical and Drug Induced Liver Injury; Epitopes; Female; Fluorine; Fluoroacetates; Halothane; Haptens; Humans; Immunoblotting; Rabbits; Serum Albumin; Trifluoroacetic Acid; Vaccines, Synthetic

1990
Screening for antibodies associated with halothane hepatitis.
    British journal of anaesthesia, 1991, Volume: 67, Issue:6

    Topics: Animals; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Fluoroacetates; Halothane; Hepatitis Antibodies; Humans; Infant; Lysine; Male; Microsomes, Liver; Rabbits; Serum Albumin; Trifluoroacetic Acid

1991
Aerobic dehalogenation of halothane showing different substrate dependency from anaerobic dehalogenation in liver microsomes of guinea pig.
    Hiroshima journal of medical sciences, 1991, Volume: 40, Issue:1

    Topics: Aerobiosis; Animals; Chemical and Drug Induced Liver Injury; Guinea Pigs; Halothane; In Vitro Techniques; Male; Microsomes, Liver; Trifluoroacetic Acid

1991
The effect of alcohol and anesthetic metabolites on cell membranes. A possible direct immune mechanism.
    Annals of the New York Academy of Sciences, 1991, Volume: 625

    Topics: Acetaldehyde; Alcoholism; Animals; Antibody Formation; Cell Membrane; Chemical and Drug Induced Liver Injury; Ethanol; Flow Cytometry; Halothane; Haptens; Humans; Immunoglobulin G; Lipid Bilayers; Liver; Liver Diseases; Molecular Conformation; Phosphatidylethanolamines; Rabbits; Trifluoroacetic Acid

1991
S-ethylthiotrifluoroacetate enhancement of the immune response to halothane in the guinea pig.
    Advances in experimental medicine and biology, 1991, Volume: 283

    Topics: Animals; Antibody Formation; Antigens; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Fluoroacetates; Guinea Pigs; Halothane; Male; Proteins; Trifluoroacetic Acid

1991
Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:1

    Topics: Animals; Antibodies; Carboxylesterase; Carboxylic Ester Hydrolases; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Fluoroacetates; Halothane; Humans; Male; Microsomes, Liver; Molecular Weight; Protein Binding; Rats; Rats, Inbred Strains; Trifluoroacetic Acid

1989
Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat.
    Toxicology, 1988, Volume: 50, Issue:1

    Topics: Administration, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Halothane; Hydrocarbons, Halogenated; Hyperthyroidism; Liver Diseases; Male; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Trifluoroacetic Acid; Triiodothyronine

1988
Generation of halothane-induced immune response in a guinea pig model of halothane hepatitis.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:12

    Topics: Animals; Antibody Formation; Antigens; Chemical and Drug Induced Liver Injury; Female; Guinea Pigs; Halothane; Male; Serum Albumin; Species Specificity; Trifluoroacetic Acid

1987
Comparison of the requirements for hepatic injury with halothane and enflurane in rats.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:10

    Topics: Anesthesia, Inhalation; Animals; Biotransformation; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enflurane; Fluorides; Halothane; Hot Temperature; Hypoxia; Liver; Male; Models, Biological; Oxygen; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Trifluoroacetic Acid

1985