trifluoroacetic acid has been researched along with Acute Liver Injury, Drug-Induced in 33 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (24.24) | 18.7374 |
1990's | 17 (51.52) | 18.2507 |
2000's | 7 (21.21) | 29.6817 |
2010's | 1 (3.03) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Barat, N; Li, Z; Mellerson, JL; Njoku, DB; Rose, NR; Sharma, R; Talor, MV | 1 |
Li, Z; Mellerson, JL; Njoku, DB; Rose, NR; Sharma, R; Talor, MV; Washington, ND | 1 |
Cheng, L; Ju, C; You, Q | 1 |
Bortolato, S; Brotto, M; Gervasi, PG; Manno, M; Marini, S; Rugge, M; Zanovello, A | 1 |
Albores, A; Dekant, W; García-Latorre, EA; Manno, M; Oropeza-Hernández, LF; Quintanilla-Vega, B; Reyes-Mejía, RA; Serrano, CJ | 1 |
Fairweather, D; Frisancho-Kiss, S; Njoku, DB; Odumade, OA; Rose, NR; Talor, MV | 1 |
Cheng, L; Ju, C; Reilly, TP; Wegmann, D; You, Q | 1 |
Lin, WQ; Marsh, HM; Trudell, JR; van Dyke, RA | 1 |
Amouzadeh, HR; Pohl, LR | 1 |
Christen, U; Frey, N; Gut, J; Koch, V; Stoffler, D | 1 |
Inaba, S; Irita, K; Nawata, H; Sakaguchi, Y; Sakai, H; Takahashi, S | 1 |
Guillouzo, A; Ilyin, GP; Malledant, Y; Rissel, M; Tanguy, M | 1 |
Kenna, JG; Knight, TL; van Pelt, FN | 1 |
Kenna, JG; Martin, BM; Martin, JL; Pohl, LR; Reed, GF; Thomassen, D | 1 |
Furst, SM; Gandolfi, AJ; Gaw, HH; Luedke, D; Reich, R | 1 |
Bourdi, M; Chen, W; Duray, PH; Graf, ML; Hoet, P; Lison, D; Nelson, SD; Peter, RM; Pohl, LR; Verlinden, N | 1 |
Abu-Asab, MS; Duray, PR; Njoku, DB; Pohl, LR; Shrestha, S; Soloway, R; Tsokos, M; West, AB | 1 |
Cohen, EN; Edmunds, HN; Trudell, JR; Watson, E | 1 |
Dumonde, DC; Hamblin, A; Simpson, R; Walton, B | 1 |
McCracken, LE; Reves, JG | 1 |
Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M | 1 |
Bürgin, M; Christen, U; Gut, J; Huwyler, J; Kenna, JG | 1 |
Gandolfi, AJ; Hubbard, AK; Levy, JP; Roth, TP | 1 |
Gandolfi, AJ; Hastings, KL; Hubbard, AK; Thomas, C | 1 |
Fujii, K; Kinoshita, H; Morio, M; Nakao, M; Yuge, O | 1 |
Anderson, WR; Ardies, CM; Trudell, JR | 1 |
Butler, LE; Ferrans, VJ; Martin, BM; Martin, JL; Perrone, A; Pohl, LR; Pumford, NR; Satoh, H; Thomassen, D | 1 |
Brown, AP; Gandolfi, AJ; Hastings, KL; Schuman, S; Thomas, C | 1 |
Christ, D; Kenna, JG; Martin, JL; Pohl, LR; Satoh, H | 1 |
Christ, DD; Kenna, JG; Martin, BM; Pohl, LR; Satoh, H; Schulick, AH | 1 |
Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC | 1 |
Gandolfi, AJ; Hubbard, AK; Roth, TP; Siadat-Pajouh, M | 1 |
Brown, BR; Gandolfi, AJ; Lind, RC; Sipes, IG | 1 |
3 review(s) available for trifluoroacetic acid and Acute Liver Injury, Drug-Induced
Article | Year |
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Molecular mimicry in halothane hepatitis: biochemical and structural characterization of lipoylated autoantigens.
Topics: Autoantigens; Chemical and Drug Induced Liver Injury; Cross Reactions; Halothane; Humans; Liver Cirrhosis, Biliary; Thioctic Acid; Trifluoroacetic Acid | 1995 |
Hapten carrier conjugates associated with halothane hepatitis.
Topics: Animals; Carrier Proteins; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Halothane; Haptens; Humans; Microsomes, Liver; Rats; Trifluoroacetic Acid | 1991 |
Neoantigens associated with halothane hepatitis.
Topics: Animals; Antigens; Carrier Proteins; Chemical and Drug Induced Liver Injury; Halothane; Humans; Trifluoroacetic Acid | 1989 |
30 other study(ies) available for trifluoroacetic acid and Acute Liver Injury, Drug-Induced
Article | Year |
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IP-10 protects while MIP-2 promotes experimental anesthetic hapten - induced hepatitis.
Topics: Anesthetics; Animals; Antibodies; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Chemical and Drug Induced Liver Injury; Chemokine CXCL10; Chemokine CXCL2; Chemokine CXCL9; Cytochrome P-450 CYP2E1; Female; Haptens; Interleukin-4; Liver; Mice; Mice, Inbred BALB C; Mice, Knockout; Models, Immunological; Neutrophils; Receptors, CXCR3; Receptors, Interleukin-8B; Spleen; T-Lymphocytes; Trifluoroacetic Acid | 2009 |
Suppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury.
Topics: Adoptive Transfer; Animals; Antibodies; CD4-Positive T-Lymphocytes; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytokines; Disease Models, Animal; Female; Fluoroacetates; Homeodomain Proteins; Interleukin-10; Interleukin-4; Killer Cells, Natural; Liver; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Knockout; Models, Immunological; Natural Killer T-Cells; S100 Proteins; Spleen; T-Lymphocytes; T-Lymphocytes, Regulatory; Th1 Cells; Th2 Cells; Trifluoroacetic Acid | 2009 |
Generation of T cell responses targeting the reactive metabolite of halothane in mice.
Topics: Animals; CD40 Antigens; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Halothane; Mice; Mice, Inbred Strains; T-Lymphocytes; Toll-Like Receptors; Trifluoroacetic Acid | 2010 |
Trifluoroacetylated proteins in liver and plasma of guinea pigs treated with HCFC-123 and halothane.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Azo Compounds; Biomarkers; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Coloring Agents; Creatine Kinase; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; Halothane; Immunoblotting; Liver; Male; Proteins; Trifluoroacetic Acid | 2003 |
Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Biomarkers; Body Weight; Chemical and Drug Induced Liver Injury; Chromatin; Cytochrome P-450 CYP2E1; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Halothane; Immunohistochemistry; Indicators and Reagents; Liver; Male; Microsomes, Liver; Pyridines; Rats; Rats, Wistar; Spermatozoa; Testis; Trifluoroacetic Acid | 2003 |
A novel model of drug hapten-induced hepatitis with increased mast cells in the BALB/c mouse.
Topics: Anesthetics, Inhalation; Animals; Autoantibodies; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; Fluoroacetates; Haptens; Hepatitis, Autoimmune; Liver; Mast Cells; Mice; Mice, Inbred BALB C; S100 Proteins; Trifluoroacetic Acid | 2005 |
Role of neutrophils in a mouse model of halothane-induced liver injury.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Fluoroacetates; Halothane; Kupffer Cells; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neutrophils; Proteins; Trifluoroacetic Acid | 2006 |
Time course of 72-kilodalton heat shock protein induction and appearance of trifluoroacetyl adducts in livers of halothane-exposed rats.
Topics: Animals; Blotting, Western; Chemical and Drug Induced Liver Injury; Electrophoresis, Polyacrylamide Gel; Halothane; Heat-Shock Proteins; Indicators and Reagents; Kinetics; Liver; Male; Rats; Rats, Sprague-Dawley; Rosaniline Dyes; Staining and Labeling; Trifluoroacetic Acid | 1994 |
Processing of endoplasmic reticulum luminal antigens associated with halothane hepatitis in rat hepatocytes.
Topics: Animals; Antigens; Carrier Proteins; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Female; Half-Life; Halothane; Haptens; Liver; Proteins; Rats; Rats, Sprague-Dawley; Trifluoroacetic Acid | 1995 |
Absence of anti-trifluoroacetate antibody after halothane anaesthesia in patients exhibiting no or mild liver damage.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Anesthesia, Inhalation; Animals; Antibodies; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Electrophoresis, Polyacrylamide Gel; Female; Halothane; Humans; Immunoblotting; Infant; Liver Failure; Male; Middle Aged; Rabbits; Rats; Rats, Wistar; Serum Albumin; Trifluoroacetic Acid | 1994 |
Human hepatocytes express trifluoroacetylated neoantigens after in vitro exposure to halothane.
Topics: Antibody Specificity; Antigens; Biotransformation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Fluoroacetates; Halothane; Humans; Liver; Serum Albumin; Trifluoroacetic Acid | 1994 |
Immunity to halothane metabolite-modified proteins in halothane hepatitis.
Topics: Animals; Antibody Formation; Antigens; Biotransformation; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Immunoblotting; Liver; Male; Rabbits; Rats; Rats, Sprague-Dawley; Trifluoroacetic Acid | 1993 |
Halothane hepatitis patients have serum antibodies that react with protein disulfide isomerase.
Topics: Antibodies; Antigens; Chemical and Drug Induced Liver Injury; Halothane; Humans; Isomerases; Microsomes, Liver; Molecular Weight; Protein Disulfide-Isomerases; Trifluoroacetic Acid | 1993 |
Demonstration of a cellular immune response in halothane-exposed guinea pigs.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Antigen-Presenting Cells; Cell Division; Cells, Cultured; Chemical and Drug Induced Liver Injury; Coculture Techniques; Fluoroacetates; Guinea Pigs; Halothane; Immunity, Cellular; Kupffer Cells; Lymphocyte Activation; Lymphocytes; Male; Spleen; Trifluoroacetic Acid | 1997 |
Epidemic of liver disease caused by hydrochlorofluorocarbons used as ozone-sparing substitutes of chlorofluorocarbons.
Topics: Biomarkers; Biopsy; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Chlorofluorocarbons, Methane; Cytochrome P-450 CYP2E1; Disease Outbreaks; Humans; Immunohistochemistry; Male; Middle Aged; Occupational Exposure; Trifluoroacetic Acid | 1997 |
Subcellular localization of trifluoroacetylated liver proteins in association with hepatitis following isoflurane.
Topics: Aged; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Endarterectomy, Carotid; Humans; Immunohistochemistry; Isoflurane; Liver; Liver Function Tests; Male; Microscopy, Electron; Proteins; Subcellular Fractions; Transaminases; Trifluoroacetic Acid | 2002 |
Urinary metabolites of halothane in man.
Topics: Binding Sites; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cysteine; Ethanolamines; Fluoroacetates; Glutathione; Halothane; Heart Transplantation; Humans; Liver; Tissue Donors; Transplantation, Homologous; Trifluoroacetic Acid | 1975 |
Absence of cellular hypersensitivity in patients with unexplained hepatitis following halothane.
Topics: Anesthesia, Inhalation; Cell Migration Inhibition; Chemical and Drug Induced Liver Injury; Halothane; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Leukocytes; Liver; Lymphocyte Activation; Lymphocytes; Proteins; Serum Albumin; Trifluoroacetic Acid | 1976 |
Hepatic pathology and skin test reactions to trifluoro-acetylated autologous protein after repeated halothane anaesthesia in the guineapig.
Topics: Anesthesia, General; Animals; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Fluoroacetates; Guinea Pigs; Halothane; Liver; Serum Albumin; Skin Tests; Trifluoroacetic Acid | 1976 |
Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol.
Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Cytosol; Ethanol; Kinetics; Lethal Dose 50; Liver; Liver Diseases; Male; Microsomes, Liver; Mitochondria, Liver; NAD; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Wistar; Sensitivity and Specificity; Subcellular Fractions; Trifluoroacetic Acid; Trifluoroethanol | 1992 |
Molecular mimicry of trifluoroacetylated human liver protein adducts by constitutive proteins and immunochemical evidence for its impairment in halothane hepatitis.
Topics: Adult; Aged; Aged, 80 and over; Animals; Biopsy; Chemical and Drug Induced Liver Injury; Child, Preschool; Female; Fluoroacetates; Halothane; Humans; Immunoblotting; Immunohistochemistry; Liver; Male; Middle Aged; Molecular Weight; Proteins; Rats; Rats, Sprague-Dawley; Trifluoroacetic Acid | 1992 |
Use of structural alterations in the synthesis of halothane metabolite antigens to mimic halothane-induced immunogen.
Topics: Acetates; Acetylation; Aminocaproates; Animals; Antibodies; Chemical and Drug Induced Liver Injury; Epitopes; Female; Fluorine; Fluoroacetates; Halothane; Haptens; Humans; Immunoblotting; Rabbits; Serum Albumin; Trifluoroacetic Acid; Vaccines, Synthetic | 1990 |
Screening for antibodies associated with halothane hepatitis.
Topics: Animals; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Fluoroacetates; Halothane; Hepatitis Antibodies; Humans; Infant; Lysine; Male; Microsomes, Liver; Rabbits; Serum Albumin; Trifluoroacetic Acid | 1991 |
Aerobic dehalogenation of halothane showing different substrate dependency from anaerobic dehalogenation in liver microsomes of guinea pig.
Topics: Aerobiosis; Animals; Chemical and Drug Induced Liver Injury; Guinea Pigs; Halothane; In Vitro Techniques; Male; Microsomes, Liver; Trifluoroacetic Acid | 1991 |
The effect of alcohol and anesthetic metabolites on cell membranes. A possible direct immune mechanism.
Topics: Acetaldehyde; Alcoholism; Animals; Antibody Formation; Cell Membrane; Chemical and Drug Induced Liver Injury; Ethanol; Flow Cytometry; Halothane; Haptens; Humans; Immunoglobulin G; Lipid Bilayers; Liver; Liver Diseases; Molecular Conformation; Phosphatidylethanolamines; Rabbits; Trifluoroacetic Acid | 1991 |
S-ethylthiotrifluoroacetate enhancement of the immune response to halothane in the guinea pig.
Topics: Animals; Antibody Formation; Antigens; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Fluoroacetates; Guinea Pigs; Halothane; Male; Proteins; Trifluoroacetic Acid | 1991 |
Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase.
Topics: Animals; Antibodies; Carboxylesterase; Carboxylic Ester Hydrolases; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Fluoroacetates; Halothane; Humans; Male; Microsomes, Liver; Molecular Weight; Protein Binding; Rats; Rats, Inbred Strains; Trifluoroacetic Acid | 1989 |
Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat.
Topics: Administration, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Halothane; Hydrocarbons, Halogenated; Hyperthyroidism; Liver Diseases; Male; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Trifluoroacetic Acid; Triiodothyronine | 1988 |
Generation of halothane-induced immune response in a guinea pig model of halothane hepatitis.
Topics: Animals; Antibody Formation; Antigens; Chemical and Drug Induced Liver Injury; Female; Guinea Pigs; Halothane; Male; Serum Albumin; Species Specificity; Trifluoroacetic Acid | 1987 |
Comparison of the requirements for hepatic injury with halothane and enflurane in rats.
Topics: Anesthesia, Inhalation; Animals; Biotransformation; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enflurane; Fluorides; Halothane; Hot Temperature; Hypoxia; Liver; Male; Models, Biological; Oxygen; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Trifluoroacetic Acid | 1985 |