Page last updated: 2024-11-06

triethylenemelamine and Retinoblastoma

triethylenemelamine has been researched along with Retinoblastoma in 36 studies

Triethylenemelamine: Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.

Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)

Research Excerpts

ExcerptRelevanceReference
"Thirty-one patients treated for retinoblastoma were included in this study."1.32Visual fields in retinoblastoma survivors. ( Abramson, DH; Melson, MR; Servodidio, C, 2004)
" Dosage level is distinctly related to radiation complications, especially retinal vascular necrosis and fatal radiation-induced neoplasms."1.26Retinoblastoma. ( Ellsworth, RM, 1977)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199033 (91.67)18.7374
1990's0 (0.00)18.2507
2000's2 (5.56)29.6817
2010's1 (2.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wong, JR1
Morton, LM1
Tucker, MA1
Abramson, DH2
Seddon, JM1
Sampson, JN1
Kleinerman, RA1
HYMAN, GA8
REESE, AB7
MERRIAM, GR2
FORREST, AW3
TAPLEY, ND1
PASARELL, R1
STAMBULIE, R1
KREMENTZ, ET5
SCHLOSSER, JV5
RUMAGE, JP5
LUYPAERT, R1
KENIS, Y1
FEIND, CR3
HERTER, F1
MARKOWITZ, A1
HAMILTON, RS1
ELLSWORTH, RM6
HERRING, L2
BERKELEY, RG1
LAWTON, RL1
TAYLOR, JC1
LATOURETTE, HB1
SPALTER, HF1
FINKEL, MP1
KLIGERMAN, MM1
PALOMINO DENA, F1
Schlienger, P1
Campana, F1
Vilcoq, JR1
Asselain, B1
Dendale, R1
Desjardins, L1
Dorval, T1
Quintana, E1
Rodriguez, J1
Melson, MR1
Servodidio, C1
Judisch, GF1
Apple, DJ1
Fratkin, JD1
Chwatowa, AW1
Weinstein, ES1
Dimitrowskaja, IP1
Izikson, LJ1
Burdjanskaja, EI1
Sorokina, MN1
Timakowa, WI1
Zygulska-Mach, H1
Maciejewski, Z1
Sevel, D1
Sealy, R1
Lawton, E1
Lawhorn, TI1
Stone, HH1
Martin, JD1
Thompson, RW1
Small, RC1
Stein, JJ1
Zglińska-Pillichowa, H1
Jablońska, M1
Jerndal, T1
Lindstedt, E1
Svensson, T1
Akerskog, G1
Rissanen, PM1
Mustonen, TE1
Leuenberger, A1
Tretter, P2
Cassady, JR1
Sagerman, RH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Retinoblastoma Biomarker Study[NCT00342797]2,136 participants (Actual)Observational1993-11-17Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for triethylenemelamine and Retinoblastoma

ArticleYear
Chemotherapy in solid tumors of childhood.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Abdominal Neoplasms; Adolescent; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Eye Neopla

1972

Other Studies

35 other studies available for triethylenemelamine and Retinoblastoma

ArticleYear
Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Oct-10, Volume: 32, Issue:29

    Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Long

2014
Combination therapy of retinoblastoma with triethylene melamine and radiotherapy.
    Journal of the American Medical Association, 1956, Dec-08, Volume: 162, Issue:15

    Topics: Child; Combined Modality Therapy; Humans; Infant; Neuroectodermal Tumors, Primitive, Peripheral; Rad

1956
Combination therapy of retinoblastoma with triethylene melamine and radiotherapy.
    Journal of the American Medical Association, 1956, Dec-08, Volume: 162, Issue:15

    Topics: Child; Combined Modality Therapy; Humans; Infant; Neuroectodermal Tumors, Primitive, Peripheral; Rad

1956
Combination therapy of retinoblastoma with triethylene melamine and radiotherapy.
    Journal of the American Medical Association, 1956, Dec-08, Volume: 162, Issue:15

    Topics: Child; Combined Modality Therapy; Humans; Infant; Neuroectodermal Tumors, Primitive, Peripheral; Rad

1956
Combination therapy of retinoblastoma with triethylene melamine and radiotherapy.
    Journal of the American Medical Association, 1956, Dec-08, Volume: 162, Issue:15

    Topics: Child; Combined Modality Therapy; Humans; Infant; Neuroectodermal Tumors, Primitive, Peripheral; Rad

1956
The treatment of retinoblastoma by radiation and triethylene melamine.
    American journal of ophthalmology, 1957, Volume: 43, Issue:6

    Topics: Humans; Neuroectodermal Tumors, Primitive, Peripheral; Radiotherapy; Retinoblastoma; Triethylenemela

1957
The treatment of retinoblastoma by x-ray and triethylene melamine.
    A.M.A. archives of ophthalmology, 1958, Volume: 60, Issue:5

    Topics: Humans; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Radiotherapy; Retina; Retinal Neop

1958
Treatment of retinoblastoma.
    The Bulletin of the Tulane Medical Faculty, 1960, Volume: 19

    Topics: Humans; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Retina; Retinal Neoplasms; Retinob

1960
Treatment of retinoblastoma by fractional intra-arterial T.E.M. and x-ray therapy.
    Southern medical journal, 1963, Volume: 56

    Topics: Humans; Radiotherapy; Retinoblastoma; Triethylenemelamine; X-Ray Therapy

1963
[Triethylene melamine in the treatment of retinoblastoma].
    Bulletin de la Societe belge d'ophtalmologie, 1962, Volume: 131

    Topics: Humans; Retinoblastoma; Triethylenemelamine

1962
IMPROVEMENTS IN ISOLATION HEAD PERFUSION.
    American journal of surgery, 1963, Volume: 106

    Topics: Carcinoma, Squamous Cell; Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Child; Chordom

1963
PHOTOCOAGULATION IN THE MANAGEMENT OF BILATERAL RETINOBLASTOMA.
    Southern medical journal, 1964, Volume: 57

    Topics: Child; Disease Management; Humans; Infant; Light Coagulation; Neoplasms; Phototherapy; Retinoblastom

1964
MANAGEMENT OF RETINOBLASTOMA.
    Annals of the New York Academy of Sciences, 1964, Apr-02, Volume: 114

    Topics: Bone Marrow Examination; Child; Diathermy; Disease Management; Humans; Light Coagulation; Neoplasms;

1964
RETINOBLASTOMA: BEHAVIOR AND TREATMENT WITH FRACTIONAL IRRADIATION AND INTRA-ARTERIAL TRIETHYLENEMELAMINE.
    Annals of the New York Academy of Sciences, 1964, Apr-02, Volume: 114

    Topics: Adolescent; Child; Geriatrics; Humans; Infant; Infant, Newborn; Neoplasms; Retinoblastoma; Surgical

1964
RETINOBLASTOMA.
    Medical record and annals, 1964, Volume: 57

    Topics: Child; Genetics, Medical; Humans; Infant; Infant, Newborn; Injections; Injections, Intra-Arterial; N

1964
THE RESULTS OF COMBINATION THERAPY OF RETINOBLASTOMA. A NINE YEAR STUDY OF 250 CASES.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Child; Combined Modality Therapy; Humans; Neoplasms; Retinoblastoma; Triethylenemelamine

1964
METASTATIC RETINOBLASTOMA TREATED WITH RADIATION AND CONTINUOUS INTRA-ARTERIAL INFUSION OF TRIETHYLENEMELAMINE (NSC-9706).
    Cancer chemotherapy reports, 1964, Volume: 38

    Topics: Child; Humans; Infusions, Intra-Arterial; Injections; Injections, Intra-Arterial; Neoplasm Metastasi

1964
CHEMOTHERAPY OF RETINOBLASTOMA. INTRACAROTID ARTERIAL INFUSION AND ISOLATION HEAD AND NECK PERFUSION--TRACER STUDIES.
    Cancer, 1964, Volume: 17

    Topics: Animals; Carbon Isotopes; Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Child; Cycloph

1964
Treatment of retinoblastoma by radiation and triethylenemelamine.
    A.M.A. archives of ophthalmology, 1954, Volume: 53, Issue:4

    Topics: Humans; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Radiation; Radiotherapy; Retina; R

1954
[Treatment of retinoblastoma in the first stage (endocular). Preliminary communication].
    Gaceta medica de Mexico, 1960, Volume: 90

    Topics: Communication; Mechlorethamine; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Nitrogen M

1960
The treatment of retinoblastoma by fractional intra-arterial TEM and x-ray therapy.
    Cancer chemotherapy reports, 1962, Volume: 16

    Topics: Humans; Infusions, Parenteral; Neuroectodermal Tumors, Primitive, Peripheral; Radiotherapy; Retinobl

1962
Nonocular second primary tumors after retinoblastoma: retrospective study of 111 patients treated by electron beam radiotherapy with or without TEM.
    American journal of clinical oncology, 2004, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Chemotherapy, Adjuvant; Dose Fractionation, Radiation; Female; Hu

2004
Visual fields in retinoblastoma survivors.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2004, Volume: 122, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Child; Child, Preschool; Combined Modality Therapy; Cryotherapy;

2004
Retinoblastoma. A survivor 12 years after treatment for metastatic disease.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1980, Volume: 98, Issue:4

    Topics: Adolescent; Adult; Bone Neoplasms; Child; Child, Preschool; Eye Neoplasms; Follow-Up Studies; Humans

1980
[Results of treatment in cases with bilateral retinoblastoma (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1980, Volume: 176, Issue:5

    Topics: Child; Child, Preschool; Eye Neoplasms; Female; Humans; Infant; Male; Prospidium; Retinoblastoma; Tr

1980
[Treatment of retinoblastoma by radioactive cobalt and xenon photocoagulation].
    Modern problems in ophthalmology, 1977, Volume: 18

    Topics: Child; Child, Preschool; Cobalt Radioisotopes; Eye Neoplasms; Female; Humans; Infant; Light Coagulat

1977
Retinoblastoma.
    Modern problems in ophthalmology, 1977, Volume: 18

    Topics: Aqueous Humor; Cyclophosphamide; Eye Neoplasms; Humans; Isoenzymes; L-Lactate Dehydrogenase; Mutatio

1977
Retinoblastoma at Groote Schuur Hospital 1952-1972.
    Transactions of the ophthalmological societies of the United Kingdom, 1973, Volume: 93, Issue:0

    Topics: Cell Survival; Cells, Cultured; Child, Preschool; Cobalt Radioisotopes; Cyclophosphamide; Dactinomyc

1973
Treatment of retinoblastoma.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1972, Volume: 114, Issue:1

    Topics: Cataract; Child; Child, Preschool; Eye Neoplasms; Female; Humans; Infant; Male; Neoplasm Metastasis;

1972
[Retinoblastoma in children (author's transl)].
    Problemy medycyny wieku rozwojowego, 1972, Volume: 2

    Topics: Age Factors; Child; Child, Preschool; Diagnosis, Differential; Eye Neoplasms; Humans; Infant; Progno

1972
Retinoblastoma in Sweden. A study of 45 children with retinoblastoma with special regard to the therapeutical results.
    Acta ophthalmologica, 1973, Volume: 51, Issue:4

    Topics: Child; Child, Preschool; Cobalt Radioisotopes; Cyclophosphamide; Diathermy; Eye Neoplasms; Female; H

1973
Combined radiation and regional chemotherapy in the treatment of retinoblastoma.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1966, Volume: 96, Issue:1

    Topics: Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Injections, Intra-Arterial; Inje

1966
Radiation therapy in retinoblastoma.
    Strahlentherapie, 1972, Volume: 143, Issue:4

    Topics: Age Factors; Child; Child, Preschool; Cobalt Isotopes; Cyclophosphamide; Eye Neoplasms; Female; Foll

1972
Retinoblastoma: behavior and treatment with fractional irradiation and intra-arterial triethylenemelamine.
    Annals of the New York Academy of Sciences, 1964, Apr-02, Volume: 114, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Injection

1964
[On the conservative treatment of retinoblastoma].
    Bibliotheca ophthalmologica : supplementa ad ophthalmologica, 1968, Volume: 75

    Topics: Child; Child, Preschool; Cobalt Isotopes; Cyclophosphamide; Eye Neoplasms; Female; Humans; Infant; L

1968
Treatment of retinoblastoma.
    American journal of ophthalmology, 1968, Volume: 66, Issue:1

    Topics: Child; Cryosurgery; Diathermy; Eye Neoplasms; Female; Humans; Injections, Intra-Arterial; Light Coag

1968
Combination therapy in retinoblastoma. A 15-year summary of methods and results.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1968, Volume: 80, Issue:6

    Topics: Carotid Arteries; Eye Neoplasms; Follow-Up Studies; Humans; Light Coagulation; Perfusion; Retinoblas

1968
Radiation therapy in retinoblastoma. An analysis of 230 cases.
    Radiology, 1969, Volume: 93, Issue:2

    Topics: Child, Preschool; Eye Neoplasms; Female; Humans; Infant; Light Coagulation; Male; Neoplasm Recurrenc

1969