Compounds > triethylenemelamine
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triethylenemelamine and Abnormalities, Autosome

triethylenemelamine has been researched along with Abnormalities, Autosome in 47 studies

Triethylenemelamine: Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.

Research Excerpts

ExcerptRelevanceReference
" Mean coefficients of variation of the G1 peaks were increased in both the low and high dosage groups relative to controls."1.28Flow-cytometric analysis of the effects of triethylenemelamine on somatic and testicular tissues of the rat. ( Bickham, JW; Burton, DW; McBee, K; Sawin, VL, 1992)
" Time-response and dose-response were studied for chromosomal aberrations induced by transplacental treatment of mouse embryos."1.27New approaches to mutagenicity studies in animals for carcinogenic and mutagenic agents. II. Clastogenic effects determined in transplacentally treated mouse embryos. ( Adler, ID, 1983)
"The effect of caffeine on the chromosomal aberrations induced in vivo by TEM and ADR was studied."1.26Effect of caffeine on the frequency of chromosome aberrations induced in vivo by triethylenemelamine (TEM) and adriamycin (ADR) in mice. ( Dulout, FN; Larramendy, ML; Olivero, OA, 1981)
"Induction of chromosome aberrations in pachytene spermatocytes of mice by 2 mg/kg TEM was compared with induction by 400 R X rays."1.26Delayed formation of chromosome aberrations in mouse pachytene spermatocytes treated with triethylenemelamine (TEM). ( Cacheiro, NL; Generoso, WM; Krishna, M; Sotomayor, RE, 1977)
"Triethylenemelamine (TEM) was used at doses of 100, 200, 300 and 400 microgram/kg to induce clastogenic effects; results were compared to those of a control group of untreated animals."1.26A collaborative cytogenetics study to measure and minimize interlaboratory variation. ( Benge, MC; Kilian, DJ; Legator, MS; Moreland, FM; Whorton, EB, 1977)
" Highter TEM dosage increased the rate of embryonic loss."1.25[Investigations on the mutagenic effect of triethylenemelamine (TEM) on early embryonic tissue and bone marrow of the rat by chromosome analysis (author's transl)]. ( Grawit, G; Michelmann, HW; Paufler, S; Sterner, W, 1975)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199041 (87.23)18.7374
1990's6 (12.77)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HAMPEL, KE1
GERHARTZ, H1
Cattanach, BM2
Adler, ID2
Generoso, WM4
Levine, BS1
Pergament, E1
Driscoll, K1
Schlegel, R1
MacGregor, JT1
Dulout, FN2
Larramendy, ML2
Olivero, OA2
Whorton, EB3
Kilian, DJ3
Kamiguchi, Y1
Tateno, H1
Iizawa, Y1
Mikamo, K1
Rieger, R8
Michaelis, A8
Caine, A2
Lyon, MF3
Huff, SW1
Cain, KT1
McKinnell, RG1
Picciano, DJ1
Schaad, JW1
Bee, DE1
Benge, MC2
Sheu, CJ1
Meyne, J1
Lockhart, LH1
Arrighi, FE1
Luippold, HE1
Gooch, PC1
Brewen, JG2
Steelman, JR1
Schreiner, CA1
Payne, HS1
Bürki, K1
Sheridan, W1
Krishna, M1
Sotomayor, RE1
Cacheiro, NL1
Hitotsumachi, S1
Kikuchi, Y1
Moreland, FM1
Legator, MS2
Michelmann, HW1
Grawit, G1
Sterner, W1
Paufler, S1
Matter, BE2
Jaeger, I1
Takehisa, S2
Bickham, JW1
Sawin, VL1
Burton, DW1
McBee, K1
Schubert, I1
Velemínský, J1
Gichner, T1
Angelis, KJ1
Nicoloff, H2
Jellema, MM1
Schardein, JL1
Slizynska, H1
Roderick, TH1
Hawes, NL1
Grauwiler, J1
Lim, JK1
Snyder, LA1
Michel, TM1
Bournique, CP1
Deysson, G1
Williams, CE1
Smith, BD1
Chang, TH1
Klassen, W1

Other Studies

47 other studies available for triethylenemelamine and Abnormalities, Autosome

ArticleYear
[STRUCTURAL ABNORMALITIES OF HUMAN LEUKOCYTE CHROMOSOMES INDUCED IN VITRO TRIETHYLENE MELAMINE].
    Experimental cell research, 1965, Volume: 37

    Topics: Chromosome Aberrations; Chromosomes, Human; Humans; In Vitro Techniques; Leukocytes; Pharmacology; R

1965
Induction of paternal sex-chromosome losses and deletions and of autosomal gene mutations by the treatment of mouse post-meiotic germ cells with triethylenemelamine.
    Mutation research, 1967, Volume: 4, Issue:1

    Topics: Animals; Chromosome Aberrations; Chromosome Disorders; Female; Fertility; Germ Cells; Male; Mice; Mu

1967
New approaches to mutagenicity studies in animals for carcinogenic and mutagenic agents. II. Clastogenic effects determined in transplacentally treated mouse embryos.
    Teratogenesis, carcinogenesis, and mutagenesis, 1983, Volume: 3, Issue:4

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Bleomycin; Chromosome Aberrations; Embryo, Mammalian; Female;

1983
Repair in fertilized eggs of mice and its role in the production of chromosomal aberrations.
    Basic life sciences, 1980, Volume: 15

    Topics: Animals; Chromosome Aberrations; DNA Repair; Ethyl Methanesulfonate; Female; Genes, Dominant; Genes,

1980
Dose- and time-response relationships of triethylenemelamine-induced chromosomal aberrations in rat bone marrow cells.
    Toxicology letters, 1982, Volume: 10, Issue:2-3

    Topics: Animals; Bone Marrow; Chromosome Aberrations; Dose-Response Relationship, Drug; Male; Rats; Rats, In

1982
The persistence of micronuclei in peripheral blood erythrocytes: detection of chronic chromosome breakage in mice.
    Mutation research, 1982, Volume: 104, Issue:6

    Topics: Animals; Cell Nucleus; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Erythrocytes; Male

1982
Effect of caffeine on the frequency of chromosome aberrations induced in vivo by triethylenemelamine (TEM) and adriamycin (ADR) in mice.
    Mutation research, 1981, Volume: 82, Issue:2

    Topics: Animals; Caffeine; Chromosome Aberrations; Chromosomes; Dose-Response Relationship, Drug; Doxorubici

1981
The influence of multiple scorers on cytogenetics study results.
    Mutation research, 1981, Volume: 85, Issue:3

    Topics: Chromosome Aberrations; Chromosomes; Genetic Variation; Humans; Karyotyping; Metaphase; Mutagenicity

1981
Enhancement by caffeine of the frequency of anaphase-telophase chromatin bridges induced by triethylenemelamine (TEM).
    Experientia, 1980, Mar-15, Volume: 36, Issue:3

    Topics: Anaphase; Animals; Caffeine; Cell Cycle; Cells, Cultured; Chromatin; Chromosome Aberrations; Criceti

1980
Chromosome analysis of human spermatozoa exposed to antineoplastic agents in vitro.
    Mutation research, 1995, Volume: 326, Issue:2

    Topics: Animals; Antineoplastic Agents; Bleomycin; Cattle; Chromosome Aberrations; Cricetinae; Cyclophospham

1995
Combined application of MH and TEM for conditioning treatment simultaneously triggers two protective functions against induction of chromatid aberrations in Vicia faba root tip meristem cells.
    Mutation research, 1993, Volume: 302, Issue:3

    Topics: Adaptation, Physiological; Chromosome Aberrations; Fabaceae; Maleic Hydrazide; Mutagens; Plants, Med

1993
Inhibition of protein synthesis by cycloheximide does not prevent adaptive responses triggered by heavy metal salts in Vicia faba.
    Mutation research, 1993, Volume: 302, Issue:3

    Topics: Adaptation, Physiological; Cadmium; Cadmium Compounds; Chromosome Aberrations; Copper; Copper Sulfat

1993
The induction of chromosome aberrations in mouse dictyate oocytes by X-rays and chemical mutagens.
    Mutation research, 1977, Volume: 45, Issue:3

    Topics: 1-Propanol; Animals; Chromosome Aberrations; Chromosomes; Female; Mesylates; Mice; Mutagens; Oocytes

1977
Reproductive capacity and dominant lethal mutations in female guinea-pigs and Djungarian hamsters following X-rays or chemical mutagens.
    Mutation research, 1979, Volume: 59, Issue:2

    Topics: Animals; Chromosome Aberrations; Cricetinae; Female; Genes, Dominant; Genes, Lethal; Guinea Pigs; Li

1979
Relative rates at which dominant-lethal mutations and heritable translocations are induced by alkylating chemicals in postmeiotic male germ cells of mice.
    Genetics, 1979, Volume: 93, Issue:1

    Topics: Alkylating Agents; Animals; Chromosome Aberrations; DNA Repair; Ethyl Methanesulfonate; Female; Gene

1979
Dominant lethality in frog embryos after paternal treatment with triethylenemelamine: cytogenetics, morphology, and swimming capability.
    Environmental mutagenesis, 1979, Volume: 1, Issue:3

    Topics: Animals; Chromosome Aberrations; Chromosomes; Embryo, Nonmammalian; Genes, Dominant; Genes, Lethal;

1979
The impact of severely damaged cells in cytogenetic research.
    Mutation research, 1979, Volume: 64, Issue:2

    Topics: Chromosome Aberrations; Genetic Variation; Humans; Mutagens; Probability; Research Design; Triethyle

1979
Collaborative studies on cytogenetic and dominant lethal assays.
    Journal - Association of Official Analytical Chemists, 1979, Volume: 62, Issue:4

    Topics: Animals; Bone Marrow Examination; Chromosome Aberrations; Cytogenetics; DDT; Female; Genes, Dominant

1979
Nonrandom distribution of chromosomal aberrations induced by three chemicals.
    Mutation research, 1979, Volume: 63, Issue:1

    Topics: Cells, Cultured; Chromosome Aberrations; Chromosome Banding; Chromosomes; Cisplatin; Cytarabine; Gen

1979
The production of chromosome aberrations in various mammalian cells by triethylenemelamine.
    Genetics, 1978, Volume: 88, Issue:2

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; Chromosomes; Dose-

1978
Triethylenemelamine: comparative cytogenetic effects induced by oral or parenteral routes of administration in rats.
    Toxicology and applied pharmacology, 1977, Volume: 42, Issue:3

    Topics: Administration, Oral; Animals; Chromosome Aberrations; Chromosome Disorders; Dose-Response Relations

1977
Studies on chemically induced dominant lethality. III. Cytogenetic analyses of TEM-effects on maturing dictyate mouse oocytes.
    Mutation research, 1978, Volume: 50, Issue:1

    Topics: Animals; Chromosome Aberrations; Chromosomes; Female; Meiosis; Mice; Mitosis; Oocytes; Ovum; Time Fa

1978
Expression of TEM-induced damage to postmeiotic stages of spermatogenesis of the mouse during early embryogenesis. II. Cytological investigations.
    Mutation research, 1978, Volume: 52, Issue:1

    Topics: Animals; Chromosome Aberrations; Chromosomes; Female; Gene Frequency; Genes, Dominant; Genes, Lethal

1978
Delayed formation of chromosome aberrations in mouse pachytene spermatocytes treated with triethylenemelamine (TEM).
    Genetics, 1977, Volume: 85, Issue:1

    Topics: Animals; Chromosome Aberrations; Male; Meiosis; Mice; Mutagens; Spermatocytes; Spermatozoa; Triethyl

1977
Chromosome aberrations and dominant lethality of mouse embryos after paternal treatment with triethylenemelamine.
    Mutation research, 1977, Volume: 42, Issue:1

    Topics: Animals; Chromosome Aberrations; Embryo, Mammalian; Female; Gene Frequency; Genes, Dominant; Genes,

1977
A collaborative cytogenetics study to measure and minimize interlaboratory variation.
    Mutation research, 1977, Volume: 44, Issue:1

    Topics: Animals; Chromosome Aberrations; Cytogenetics; Dose-Response Relationship, Drug; Rats; Specimen Hand

1977
[Investigations on the mutagenic effect of triethylenemelamine (TEM) on early embryonic tissue and bone marrow of the rat by chromosome analysis (author's transl)].
    Mutation research, 1975, Volume: 27, Issue:3

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; Corpus Luteum; Embryo,

1975
Proceedings: Primordial germ cell sensitivity to mutagenic effects of TEM.
    Mutation research, 1975, Volume: 29, Issue:2

    Topics: Animals; Chromosome Aberrations; Female; Germ Cells; Male; Mice; Mutagens; Oogonia; Spermatocytes; S

1975
Premature chromosome condensation, structural chromosome aberrations, and micronuclei in early mouse embryos after treatment of paternal postmeiotic germ cells with triethylenemelamine: possible mechanisms for chemically induced dominant-lethal mutatiions
    Mutation research, 1975, Volume: 33, Issue:2-3

    Topics: Animals; Cell Nucleus; Chromosome Aberrations; Chromosomes; Embryonic Development; Female; Genes, Do

1975
Low temperature between conditioning and challenge treatment prevents the 'adaptive response' of Vicia faba root tip meristem cells.
    Mutation research, 1992, Volume: 282, Issue:2

    Topics: Adaptation, Physiological; Cells, Cultured; Chromosome Aberrations; Fabaceae; In Vitro Techniques; M

1992
Flow-cytometric analysis of the effects of triethylenemelamine on somatic and testicular tissues of the rat.
    Cytometry, 1992, Volume: 13, Issue:4

    Topics: Animals; Bone Marrow; Cell Separation; Chromosome Aberrations; DNA; DNA Damage; Dose-Response Relati

1992
Involvement of phytochelatins in NiCl2-triggered protection against induction of chromatid aberrations by TEM and MH in Vicia faba root tip meristems?
    Mutation research, 1990, Volume: 244, Issue:1

    Topics: Buthionine Sulfoximine; Cell Division; Chromosome Aberrations; Drug Interactions; Fabaceae; Maleic H

1990
Induction of chromatid aberrations by TEM and maleic hydrazide is differently affected by pretreatment of Vicia faba root-tip meristems with methyl iodide.
    Mutation research, 1988, Volume: 208, Issue:2

    Topics: Chromatids; Chromosome Aberrations; Drug Interactions; Fabaceae; Furans; Hydrocarbons, Iodinated; Ma

1988
Effects of ethidium bromide and nalidixic acid pretreatment on the induction of chromatid aberrations by TEM and maleic hydrazide in Vicia faba main root meristems.
    Mutation research, 1988, Volume: 208, Issue:2

    Topics: Chromatids; Chromosome Aberrations; DNA Repair; Drug Interactions; Ethidium; Fabaceae; Maleic Hydraz

1988
Effects of novobiocin on heat shock protection against chromatid aberration induction by triethylenemelamine (TEM) and maleic hydrazide (MH) in Vicia faba.
    Mutation research, 1988, Volume: 208, Issue:3-4

    Topics: Chromosome Aberrations; Hot Temperature; In Vitro Techniques; Maleic Hydrazide; Mutation; Novobiocin

1988
The cytogenetic effect of triethylenemelamine in the rat as evaluated by the micronucleus test.
    Toxicology and applied pharmacology, 1974, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Cell Nucleus; Chromosome Aberrations; Dose-Respon

1974
Cytological analysis of storage effects on various types of complete and mosaic change induced in drosophila chromosomes by some chemical mutagens.
    Mutation research, 1973, Volume: 19, Issue:2

    Topics: Animals; Azirines; Chromosome Aberrations; Chromosomes; Drosophila melanogaster; Formaldehyde; Male;

1973
Evaluation of chromosome aberration effects of chemicals on mouse germ cells.
    Environmental health perspectives, 1973, Volume: 6

    Topics: Alkylating Agents; Animals; Cell Division; Chromosome Aberrations; Dose-Response Relationship, Drug;

1973
Nineteen paracentric chromosomal inversions in mice.
    Genetics, 1974, Volume: 76, Issue:1

    Topics: Animals; Chromosome Aberrations; Chromosomes; Dose-Response Relationship, Drug; Dose-Response Relati

1974
Micronuclei in mouse bone-marrow cells. A simple in vivo model for the evaluation of drug-induced chromosomal aberrations.
    Mutation research, 1974, Volume: 23, Issue:2

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Caffeine; Cell Nucleus; Chromosome Aberrations; Colchicine;

1974
Cytogenetic and complementation analyses of recessive lethal mutations induced in the X chromosome of Drosophila by three alkylating agents.
    Genetical research, 1974, Volume: 24, Issue:1

    Topics: Alkylating Agents; Animals; Aziridines; Chromosome Aberrations; Chromosome Mapping; Drosophila melan

1974
DNA repair synthesis and chromosomal aberrations induced in vivo by triethylenemelamine.
    Mutation research, 1974, Volume: 24, Issue:1

    Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; DNA Repair; Dose-R

1974
[Distribution of chromosomal fragments induced by methoxy-9 ellipticin lactate in human diploid cells cultivated in vitro].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Jun-21, Volume: 272, Issue:25

    Topics: Alkaloids; Chromosome Aberrations; Chromosomes; Culture Techniques; Diploidy; Fibroblasts; Humans; L

1971
A search for chromosome aberrations induced in mouse spermatogonia by chemical mutagens.
    Mutation research, 1971, Volume: 13, Issue:4

    Topics: Age Factors; Animals; Chromosome Aberrations; Male; Meiosis; Mice; Mutagens; Mutation; Spermatogenes

1971
Species comparisons concerning radiation-induced dominant lethals and chromosome aberrations.
    Mutation research, 1971, Volume: 11, Issue:1

    Topics: Animals; Chromosome Aberrations; Cricetinae; Female; Genes, Dominant; Genes, Lethal; Germ Cells; Gui

1971
Comparative effects of tretamine, tepa, apholate and their structural analogs on human chromsomes in vitro.
    Chromosoma, 1968, Volume: 24, Issue:3

    Topics: Antineoplastic Agents; Azirines; Chemosterilants; Chromosome Aberrations; Humans; In Vitro Technique

1968
Chemical induction of heat-reversible 'potential lesions' in Vicia faba chromosome.
    Nature, 1965, May-15, Volume: 206, Issue:985

    Topics: Chromosome Aberrations; Chromosome Disorders; In Vitro Techniques; Plant Cells; Triethylenemelamine

1965