trientine has been researched along with Orphan Diseases in 2 studies
Trientine: An ethylenediamine derivative used as stabilizer for EPOXY RESINS, as ampholyte for ISOELECTRIC FOCUSING and as chelating agent for copper in HEPATOLENTICULAR DEGENERATION.
TETA : An azamacrocyle in which four nitrogen atoms at positions 1, 4, 8 and 11 of a fouteen-membered ring are each substituted with a carboxymethyl group.
2,2,2-tetramine : A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens.
Orphan Diseases: Rare diseases that have not been well studied.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Copper overload in patients with Wilson's disease is caused by impairment to the biliary route for excretion of dietary copper A combination of neurological, psychiatric and hepatic symptoms can make the diagnosis of Wilson's disease challenging." | 2.49 | The treatment of Wilson's disease, a rare genetic disorder of copper metabolism. ( Purchase, R, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Purchase, R | 1 |
| Roberts, EA | 1 |
| Herder, M | 1 |
| Hollis, A | 1 |
2 reviews available for trientine and Orphan Diseases
| Article | Year |
|---|---|
The treatment of Wilson's disease, a rare genetic disorder of copper metabolism.
Topics: Brain; Chelating Agents; Copper; Cornea; Dimercaprol; Drug Discovery; Hepatolenticular Degeneration; | 2013 |
Fair pricing of "old" orphan drugs: considerations for Canada's orphan drug policy.
Topics: Canada; Chelating Agents; Costs and Cost Analysis; Drug Costs; Health Policy; Hepatolenticular Degen | 2015 |