trientine has been researched along with Hepatitis in 3 studies
Trientine: An ethylenediamine derivative used as stabilizer for EPOXY RESINS, as ampholyte for ISOELECTRIC FOCUSING and as chelating agent for copper in HEPATOLENTICULAR DEGENERATION.
TETA : An azamacrocyle in which four nitrogen atoms at positions 1, 4, 8 and 11 of a fouteen-membered ring are each substituted with a carboxymethyl group.
2,2,2-tetramine : A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens.
Hepatitis: INFLAMMATION of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined the effects of trientine on the spontaneous development of hepatitis and hepatic tumors, by its short-term and long-term administration to Long-Evans cinnamon (LEC) rats with an accumulation of copper in the liver, as animal models of Wilson's disease." | 5.29 | Inhibition of hereditary hepatitis and liver tumor development in Long-Evans cinnamon rats by the copper-chelating agent trientine dihydrochloride. ( Maeda, M; Mori, M; Nagao, M; Sone, K; Sugimura, T; Takeichi, N; Wakabayashi, K, 1996) |
| "The discovery that the gene for Wilson disease encodes a copper-transporting ATPase has greatly improved our understanding of the pathophysiology of this disorder and of copper metabolism in humans." | 2.39 | Wilson disease: genetic basis of copper toxicity and natural history. ( Schilsky, ML, 1996) |
| " We examined the effects of trientine on the spontaneous development of hepatitis and hepatic tumors, by its short-term and long-term administration to Long-Evans cinnamon (LEC) rats with an accumulation of copper in the liver, as animal models of Wilson's disease." | 1.29 | Inhibition of hereditary hepatitis and liver tumor development in Long-Evans cinnamon rats by the copper-chelating agent trientine dihydrochloride. ( Maeda, M; Mori, M; Nagao, M; Sone, K; Sugimura, T; Takeichi, N; Wakabayashi, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Talbot, C | 1 |
| Kearns, S | 1 |
| Mouser, PJ | 1 |
| Sone, K | 1 |
| Maeda, M | 1 |
| Wakabayashi, K | 1 |
| Takeichi, N | 1 |
| Mori, M | 1 |
| Sugimura, T | 1 |
| Nagao, M | 1 |
| Schilsky, ML | 1 |
1 review available for trientine and Hepatitis
| Article | Year |
|---|---|
Wilson disease: genetic basis of copper toxicity and natural history.
Topics: Adenosine Triphosphatases; Carrier Proteins; Cation Transport Proteins; Chelating Agents; Chelation | 1996 |
2 other studies available for trientine and Hepatitis
| Article | Year |
|---|---|
Treatment of Superficial Necrolytic Dermatitis with Copper Chelationina Dog with Copper-Associated Hepatitis.
Topics: Animals; Copper; Dermatitis; Dog Diseases; Dogs; Hepatitis; Male; Skin Diseases; Trientine | 2023 |
Inhibition of hereditary hepatitis and liver tumor development in Long-Evans cinnamon rats by the copper-chelating agent trientine dihydrochloride.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chelating Agents; Copper; Hepatitis; Liv | 1996 |