trientine has been researched along with Heart Failure in 1 studies
Trientine: An ethylenediamine derivative used as stabilizer for EPOXY RESINS, as ampholyte for ISOELECTRIC FOCUSING and as chelating agent for copper in HEPATOLENTICULAR DEGENERATION.
TETA : An azamacrocyle in which four nitrogen atoms at positions 1, 4, 8 and 11 of a fouteen-membered ring are each substituted with a carboxymethyl group.
2,2,2-tetramine : A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral trientine treatment also caused elevated Cu excretion in humans with type 2 diabetes, in whom 6 months of treatment caused elevated left ventricular mass to decline significantly toward normal." | 1.32 | Regeneration of the heart in diabetes by selective copper chelation. ( Allen, GR; Baker, JR; Borg, TK; Boyd, PD; Brunton, DH; Chan, YK; Choong, SY; Cooper, GJ; Cowan, BR; Crossman, DJ; Dissanayake, AM; Doughty, RN; Gamble, GD; Keogh, GF; Leahy, FE; Leonard, BL; Occleshaw, CJ; Phillips, AR; Pope, AJ; Poppitt, SD; Saafi, 'L; Young, AA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cooper, GJ | 1 |
| Phillips, AR | 1 |
| Choong, SY | 1 |
| Leonard, BL | 1 |
| Crossman, DJ | 1 |
| Brunton, DH | 1 |
| Saafi, 'L | 1 |
| Dissanayake, AM | 1 |
| Cowan, BR | 1 |
| Young, AA | 1 |
| Occleshaw, CJ | 1 |
| Chan, YK | 1 |
| Leahy, FE | 1 |
| Keogh, GF | 1 |
| Gamble, GD | 1 |
| Allen, GR | 1 |
| Pope, AJ | 1 |
| Boyd, PD | 1 |
| Poppitt, SD | 1 |
| Borg, TK | 1 |
| Doughty, RN | 1 |
| Baker, JR | 1 |
1 other study available for trientine and Heart Failure
| Article | Year |
|---|---|
Regeneration of the heart in diabetes by selective copper chelation.
Topics: Animals; Chelating Agents; Copper; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetic Angio | 2004 |