trientine has been researched along with Angiogenesis, Pathologic in 6 studies
Trientine: An ethylenediamine derivative used as stabilizer for EPOXY RESINS, as ampholyte for ISOELECTRIC FOCUSING and as chelating agent for copper in HEPATOLENTICULAR DEGENERATION.
TETA : An azamacrocyle in which four nitrogen atoms at positions 1, 4, 8 and 11 of a fouteen-membered ring are each substituted with a carboxymethyl group.
2,2,2-tetramine : A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined the effects of treatment with trientine, a copper-chelating agent, on tumor development in a murine xenograft model using fibrosarcoma-derived transplantable QRsp-11 cells and C57BL/6 mice and induction of apoptosis in tumor cells and endothelial cells in vivo and in vitro." | 7.74 | Trientine, a copper-chelating agent, induced apoptosis in murine fibrosarcoma cells in vivo and in vitro. ( Chiba, T; Endoh, D; Hayashi, M; Kon, Y; Nishiya, H; Okui, T, 2007) |
| " We examined the effects of treatment with trientine, a copper-chelating agent, on tumor development in a murine xenograft model using fibrosarcoma-derived transplantable QRsp-11 cells and C57BL/6 mice and induction of apoptosis in tumor cells and endothelial cells in vivo and in vitro." | 3.74 | Trientine, a copper-chelating agent, induced apoptosis in murine fibrosarcoma cells in vivo and in vitro. ( Chiba, T; Endoh, D; Hayashi, M; Kon, Y; Nishiya, H; Okui, T, 2007) |
| "Trientine treatment resulted in a marked suppression of neovascularization and increase of apoptosis in the tumor, whereas tumor cell proliferation itself was not altered." | 1.31 | The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells. ( De Lorenzo, MS; Fukui, H; Gomez, DE; Ikenaka, Y; Kishida, H; Kuriyama, S; Nakae, D; Nakatani, T; Noguchi, R; Okuda, H; Tejera, AM; Tsujinoue, H; Yoshii, J; Yoshiji, H, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nasulewicz, A | 1 |
| Opolski, A | 1 |
| Sproull, M | 1 |
| Brechbiel, M | 1 |
| Camphausen, K | 1 |
| Yoshiji, H | 2 |
| Yoshii, J | 2 |
| Kuriyama, S | 2 |
| Ikenaka, Y | 2 |
| Noguchi, R | 2 |
| Yanase, K | 1 |
| Namisaki, T | 1 |
| Kitade, M | 1 |
| Yamazaki, M | 1 |
| Fukui, H | 2 |
| Brewer, GJ | 1 |
| Hayashi, M | 1 |
| Nishiya, H | 1 |
| Chiba, T | 1 |
| Endoh, D | 1 |
| Kon, Y | 1 |
| Okui, T | 1 |
| Okuda, H | 1 |
| Tsujinoue, H | 1 |
| Nakatani, T | 1 |
| Kishida, H | 1 |
| Nakae, D | 1 |
| Gomez, DE | 1 |
| De Lorenzo, MS | 1 |
| Tejera, AM | 1 |
3 reviews available for trientine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
[The role of copper in tumor angiogenesis--clinical implications].
Topics: Animals; Captopril; Copper; Humans; Neoplasms; Neovascularization, Pathologic; Oxidation-Reduction; | 2002 |
Antiangiogenic therapy through copper chelation.
Topics: Angiogenesis Inhibitors; Animals; Chelating Agents; Chelation Therapy; Copper; Corneal Neovasculariz | 2003 |
Anticopper therapy against cancer and diseases of inflammation and fibrosis.
Topics: Animals; Copper; Fibrosis; Humans; Inflammation; Molybdenum; Neoplasms; Neovascularization, Patholog | 2005 |
3 other studies available for trientine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Combination of copper-chelating agent, trientine, and methotrexate attenuates colorectal carcinoma development and angiogenesis in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Vessels; Cell Line; Cell Line, Tumor; | 2005 |
Trientine, a copper-chelating agent, induced apoptosis in murine fibrosarcoma cells in vivo and in vitro.
Topics: Animals; Apoptosis; Cattle; Cell Survival; Chelating Agents; Endothelial Cells; Fibrosarcoma; Flow C | 2007 |
The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells.
Topics: Animals; Apoptosis; Cell Division; Chelating Agents; Copper; Female; Liver Neoplasms, Experimental; | 2001 |