triclosan has been researched along with Malaria in 11 studies
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we report synthetic chemistry and transfection studies concluding that Plasmodium FabI is not the target of the antimalarial activity of triclosan, an inhibitor of bacterial FabI." | 3.74 | The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites. ( Ager, A; Coppi, A; Falkard, B; Fidock, DA; Freundlich, JS; Gratraud, P; Heussler, V; Jacobs, WR; Jacobus, DP; Janse, CJ; Kelly, BJ; Kremer, L; Kumar, TR; Lakshmanan, V; Li, CD; Moura, PA; Nkrumah, LJ; Purcell, LA; Retzlaff, S; Sacchettini, JC; Schiehser, G; Sidhu, AB; Siedner, M; Sinnis, P; Tsai, JH; Valderramos, JC; Vilcheze, C; Waters, AP; Yu, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lauinger, IL | 1 |
| Vivas, L | 1 |
| Perozzo, R | 2 |
| Stairiker, C | 1 |
| Tarun, A | 1 |
| Zloh, M | 1 |
| Zhang, X | 1 |
| Xu, H | 1 |
| Tonge, PJ | 1 |
| Franzblau, SG | 1 |
| Pham, DH | 1 |
| Esguerra, CV | 1 |
| Crawford, AD | 2 |
| Maes, L | 1 |
| Tasdemir, D | 2 |
| Carballeira, NM | 1 |
| Bwalya, AG | 1 |
| Itoe, MA | 1 |
| Andricopulo, AD | 1 |
| Cordero-Maldonado, ML | 1 |
| Kaiser, M | 1 |
| Mota, MM | 1 |
| Guido, RV | 1 |
| LIVADAS, G | 1 |
| BELIOS, G | 1 |
| Yu, M | 1 |
| Kumar, TR | 2 |
| Nkrumah, LJ | 1 |
| Coppi, A | 1 |
| Retzlaff, S | 1 |
| Li, CD | 1 |
| Kelly, BJ | 1 |
| Moura, PA | 1 |
| Lakshmanan, V | 1 |
| Freundlich, JS | 1 |
| Valderramos, JC | 1 |
| Vilcheze, C | 1 |
| Siedner, M | 1 |
| Tsai, JH | 1 |
| Falkard, B | 1 |
| Sidhu, AB | 1 |
| Purcell, LA | 1 |
| Gratraud, P | 1 |
| Kremer, L | 1 |
| Waters, AP | 1 |
| Schiehser, G | 1 |
| Jacobus, DP | 1 |
| Janse, CJ | 1 |
| Ager, A | 1 |
| Jacobs, WR | 2 |
| Sacchettini, JC | 3 |
| Heussler, V | 1 |
| Sinnis, P | 1 |
| Fidock, DA | 4 |
| Baschong, W | 1 |
| Wittlin, S | 1 |
| Inglis, KA | 1 |
| Fairlamb, AH | 1 |
| Croft, SL | 1 |
| Brun, R | 1 |
| Kuo, MR | 2 |
| Morbidoni, HR | 1 |
| Alland, D | 1 |
| Sneddon, SF | 1 |
| Gourlie, BB | 1 |
| Staveski, MM | 1 |
| Leonard, M | 1 |
| Gregory, JS | 1 |
| Janjigian, AD | 1 |
| Yee, C | 1 |
| Musser, JM | 1 |
| Kreiswirth, B | 1 |
| Iwamoto, H | 1 |
| VISWANATHAN, DK | 1 |
| RAMACHANDRA RAO, T | 1 |
| BHATIA, SC | 1 |
| Rao, SP | 1 |
| Surolia, A | 3 |
| Surolia, N | 3 |
| Nicola, G | 1 |
| Smith, CA | 1 |
| Lucumi, E | 1 |
| Karagyozov, L | 1 |
| Abagyan, R | 1 |
| RamachandraRao, SP | 1 |
1 review available for triclosan and Malaria
| Article | Year |
|---|---|
Triclosan: a shot in the arm for antimalarial chemotherapy.
Topics: Animals; Antimalarials; Drug Resistance; Fatty Acids; Humans; Malaria; Protein Structure, Tertiary; | 2003 |
10 other studies available for triclosan and Malaria
| Article | Year |
|---|---|
Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target.
Topics: Animals; Antimalarials; Disease Models, Animal; Enzyme Inhibitors; Fatty Acid Synthase, Type II; Hep | 2013 |
2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes.
Topics: Animals; Antimalarials; Cell Line, Tumor; Dose-Response Relationship, Drug; Fatty Acid Synthase, Typ | 2014 |
Postwar malaria control in Greece on basis of epidemiological data.
Topics: Greece; Humans; Malaria; Triclosan | 1948 |
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.
Topics: Animals; Antimalarials; Gene Deletion; Liver; Malaria; Mice; Mice, Inbred C57BL; Mutagenesis, Insert | 2008 |
Triclosan is minimally effective in rodent malaria models.
Topics: Animals; Anti-Infective Agents, Local; Humans; Malaria; Mice; Plasmodium; Plasmodium berghei; Reprod | 2011 |
Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data.
Topics: Animals; Anti-Infective Agents, Local; Bacterial Proteins; Dinitrobenzenes; Enoyl-(Acyl-Carrier-Prot | 2003 |
The validity of estimation of Anopheles densities on the basis of hand collection on a timed basis from fixed catching stations.
Topics: Animals; Anopheles; Culicidae; Hand; Humans; Malaria; Triclosan | 1952 |
Discovery of novel inhibitors targeting enoyl-acyl carrier protein reductase in Plasmodium falciparum by structure-based virtual screening.
Topics: Animals; Antimalarials; Binding Sites; Caco-2 Cells; Crystallography, X-Ray; Drug Design; Drug Evalu | 2007 |
Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum.
Topics: Amino Acid Sequence; Animals; Antimalarials; Disease Models, Animal; Enoyl-(Acyl-Carrier-Protein) Re | 2001 |
Paradigm shifts in malaria parasite biochemistry and anti-malarial chemotherapy.
Topics: Animals; Antimalarials; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Fatty Acid | 2002 |