Compounds > triclosan
Page last updated: 2024-11-05

triclosan and Leg Ulcer

triclosan has been researched along with Leg Ulcer in 4 studies

Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Research Excerpts

ExcerptRelevanceReference
"A greater emphasis on the impact of treatment on pain and healing is warranted both clinically and in research."1.33Patients' perceptions of the impact of treatments and products on their experience of leg ulcer pain. ( Briggs, M; Closs, SJ, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gloor, M1
Becker, A1
Wasik, B1
Kniehl, E1
GROSSMANN, H1
Briggs, M1
Closs, SJ1
Huber, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicentre Observational Study on the Wound Pain Relief Properties of ORTODERMINA®[NCT03720119]78 participants (Actual)Observational2015-01-27Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change of Pain Intensity From Baseline to the End of Treatment Using the 11-point Numerical Pain Rating Scale (NPRS)

"The evaluation of the pain intensity was based on a 11-point Numerical Pain Rating Scale (NPRS score from 0= no pain to 10= the most intense pain imaginable). Patients recorded the NPRS score every day of treatment in their diary.~The improvement in the pain intensity is defined as a decrease in NPRS scores from baseline to the end of treatment." (NCT03720119)
Timeframe: Every day for 15 days

InterventionScore on a scale (Mean)
NPRS score of Day 1NPRS score of Day 2NPRS score of Day 3NPRS score of Day 4NPRS score of Day 5NPRS score of Day 6NPRS score of Day 7NPRS score of Day 8NPRS score of Day 9NPRS score of Day 10NPRS score of Day 11NPRS score of Day 12NPRS score of Day 13NPRS score of Day 14NPRS score of Day 15
Single Cohort6.75.45.04.74.13.93.63.63.63.43.23.23.33.02.8

Change of Pain Relief From Baseline to the End of Treatment Using the 5-point Visual Rating Scale (VRS)

"The evaluation of wound pain relief was based on a 5-point Visual Rating Scale (0 = none improvement; 4 = total relief).~Patients recorded the VRS score every day of treatment in their diary. The improvement in the pain relief was defined as a VRS scores at end of treatment significantly greater than 0." (NCT03720119)
Timeframe: Every day for 15 days

InterventionParticipants (Count of Participants)
Day 272404424Day 372404424Day 472404424Day 572404424Day 672404424Day 772404424Day 872404424Day 972404424Day 1072404424Day 1172404424Day 1272404424Day 1372404424Day 1472404424Day 1572404424
None reliefMildComplete reliefModerateA lot
Single Cohort23
Single Cohort28
Single Cohort20
Single Cohort24
Single Cohort30
Single Cohort18
Single Cohort2
Single Cohort31
Single Cohort5
Single Cohort17
Single Cohort39
Single Cohort6
Single Cohort21
Single Cohort33
Single Cohort9
Single Cohort16
Single Cohort35
Single Cohort7
Single Cohort25
Single Cohort10
Single Cohort22
Single Cohort12
Single Cohort14
Single Cohort11
Single Cohort3
Single Cohort13
Single Cohort15
Single Cohort4

Trials

1 trial available for triclosan and Leg Ulcer

ArticleYear
Role of Klion ointment in the treatment of crural ulcer.
    Therapia Hungarica (English edition), 1991, Volume: 39, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Drug Combinations; Female; Humans; Leg Ulcer; Male; Metronidazole; M

1991

Other Studies

3 other studies available for triclosan and Leg Ulcer

ArticleYear
[Triclosan, a topical dermatologic agent. In vitro- and in vivo studies on the effectiveness of a new preparation in the New German Formulary].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2002, Volume: 53, Issue:11

    Topics: Administration, Topical; Adult; Bacteria; Colony Count, Microbial; Dermatitis, Atopic; Drug Evaluati

2002
[Ambulatory therapy of ulcus cruris with a fat-free ointment basis].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1952, Dec-01, Volume: 13, Issue:11

    Topics: Humans; Leg; Leg Ulcer; Ointments; Triclosan; Ulcer

1952
Patients' perceptions of the impact of treatments and products on their experience of leg ulcer pain.
    Journal of wound care, 2006, Volume: 15, Issue:8

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents, Local; Attitude to Health; Bandages; Choice Behavior

2006