triclosan has been researched along with Health Care Associated Infection in 17 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Triclosan is a widely accepted antimicrobial ingredient because of its safety and antimicrobial efficacy." | 2.41 | Triclosan: a review of effectiveness and safety in health care settings. ( Jampani, HB; Jones, RD; Lee, AS; Newman, JL, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dittmann, K | 1 |
| Schmidt, T | 1 |
| Müller, G | 1 |
| Cuny, C | 1 |
| Holtfreter, S | 1 |
| Troitzsch, D | 1 |
| Pfaff, P | 1 |
| Hübner, NO | 1 |
| Lanini, S | 1 |
| D'Arezzo, S | 1 |
| Puro, V | 1 |
| Martini, L | 1 |
| Imperi, F | 1 |
| Piselli, P | 1 |
| Montanaro, M | 1 |
| Paoletti, S | 1 |
| Visca, P | 1 |
| Ippolito, G | 1 |
| Boyce, JM | 1 |
| Dupont, HL | 1 |
| Massaro, J | 1 |
| Sack, D | 1 |
| Schaffner, DW | 1 |
| Marchetti, MG | 1 |
| Kampf, G | 1 |
| Finzi, G | 1 |
| Salvatorelli, G | 1 |
| Worthington, T | 1 |
| Elliott, TS | 1 |
| Messager, S | 1 |
| Goddard, PA | 1 |
| Dettmar, PW | 1 |
| Maillard, JY | 1 |
| Sickbert-Bennett, EE | 1 |
| Weber, DJ | 1 |
| Gergen-Teague, MF | 1 |
| Sobsey, MD | 1 |
| Samsa, GP | 1 |
| Rutala, WA | 1 |
| Seal, LA | 1 |
| Rizer, RL | 1 |
| Maas-Irslinger, R | 1 |
| Chiappetta, DA | 1 |
| Degrossi, J | 1 |
| Teves, S | 1 |
| D'Aquino, M | 1 |
| Bregni, C | 1 |
| Sosnik, A | 1 |
| Jog, S | 1 |
| Cunningham, R | 1 |
| Cooper, S | 1 |
| Wallis, M | 1 |
| Marchbank, A | 1 |
| Vasco-Knight, P | 1 |
| Jenks, PJ | 1 |
| Barry, MA | 1 |
| Craven, DE | 1 |
| Goularte, TA | 1 |
| Lichtenberg, DA | 1 |
| McNaughton, M | 1 |
| Mazinke, N | 1 |
| Thomas, E | 1 |
| Zafar, AB | 1 |
| Butler, RC | 1 |
| Reese, DJ | 1 |
| Gaydos, LA | 1 |
| Mennonna, PA | 1 |
| Jones, RD | 1 |
| Jampani, HB | 1 |
| Newman, JL | 1 |
| Lee, AS | 1 |
| Brady, LM | 1 |
| Thomson, M | 1 |
| Palmer, MA | 1 |
| Harkness, JL | 1 |
| Gravens, DL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Residual Effect of Chlorhexidine 2% / Isopropyl Alcohol 70% Compared to Triclosan 1% / Isopropyl Alcohol 70%[NCT01762904] | Phase 3 | 135 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"135 units of measurement to test two antiseptics and two controls. Principal unit of measurement: four determinations of bacterial counts in a subject for antiseptics and controls to test each of the application sites.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 2% chlorhexidine in 70% isopropyl alcohol and 1% triclosan in 70% isopropyl alcohol, Deionized water redistilled and Scrub the skin without prior application of any substance was tested. We prepared four skin's areas of 25 cm2, two in each forearm. The solution remained on the skin for 60s, 3h and 24h.~Presence of allergy or any skin reaction at 24 hours after the antiseptic application." (NCT01762904)
Timeframe: 24 hours
| Intervention | participants (Median) |
|---|---|
| Whole Group of 135 Units of Measurement | 0 |
"135 units of measurement to test two controls. Principal unit of measurement: four determinations of bacterial counts in a subject for antiseptics and controls to test each of the application sites.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. Deionized water redistilled (Control 2: Control with scrub) and Scrub the skin without prior application of any substance (Control1: Control without scrub) was tested. Were prepared two skin's areas of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hrs
| Intervention | (CFU/cm2) (Median) | |||||
|---|---|---|---|---|---|---|
| Control 1: without scrub 0 h | Control 2: scrub with Deionized water redisti 0 h | Control 1: without scrub 3 h | Control 2: scrub with Deionized water redisti 3 h | Control 1: without scrub 24 h | Control 2: scrub with Deionized water redisti 24 h | |
| Whole Group of 135 Units of Measurement | 480 | 216 | 288 | 96 | 288 | 96 |
"135 determinations to evaluate residual effect of 2% chlorhexidine in 70% isopropyl alcohol.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 2% chlorhexidine in 70% isopropyl alcohol was tested. Were prepared the skin area of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h, everyone on different days.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hours
| Intervention | (CFU/cm2) (Median) | ||
|---|---|---|---|
| 0 h | 3 h | 24 h | |
| Whole Group of 135 Units of Measurement | 24 | 48 | 24 |
"135 determinations to test 1% triclosan in 70% isopropyl alcohol.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 1% triclosan in 70% isopropyl alcohol was tested. Were prepared the skin area of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h, everyone on different days.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hours
| Intervention | (CFU/cm2) (Median) | ||
|---|---|---|---|
| 0 h | 3 h | 24 h | |
| Whole Group of 135 Units of Measurement | 48 | 48 | 96 |
1 review available for triclosan and Health Care Associated Infection
| Article | Year |
|---|---|
Triclosan: a review of effectiveness and safety in health care settings.
Topics: Anti-Infective Agents, Local; Biological Availability; Chemistry, Pharmaceutical; Chlorhexidine; Cro | 2000 |
2 trials available for triclosan and Health Care Associated Infection
| Article | Year |
|---|---|
An expert panel report of a proposed scientific model demonstrating the effectiveness of antibacterial handwash products.
Topics: Anti-Infective Agents, Local; Chlorhexidine; Cross Infection; Cross-Over Studies; Cucumis melo; Dose | 2012 |
A unique water optional health care personnel handwash provides antimicrobial persistence and residual effects while decreasing the need for additional products.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Chlorhexidine; Cross Infection; Ethanol; Fema | 2005 |
14 other studies available for triclosan and Health Care Associated Infection
| Article | Year |
|---|---|
Susceptibility of livestock-associated methicillin-resistant
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Community-Acquired Infections; Cro | 2019 |
Molecular epidemiology of a Pseudomonas aeruginosa hospital outbreak driven by a contaminated disinfectant-soap dispenser.
Topics: Clinical Audit; Cohort Studies; Cross Infection; Disease Outbreaks; Disinfectants; Equipment Contami | 2011 |
Evaluation of the bactericidal effect of five products for surgical hand disinfection according to prEN 12054 and prEN 12791.
Topics: 1-Propanol; Alcohols; Bacteria; Chlorhexidine; Colony Count, Microbial; Cross Infection; Disinfectan | 2003 |
B4 Hand Hygienic Advanced Skin Protection(TM)-a handy adjunct in the prevention of cross-infection?
Topics: Anti-Infective Agents, Local; Attitude of Health Personnel; Cross Infection; Dermatologic Agents; Gu | 2003 |
Comparison of two in vivo and two ex vivo tests to assess the antibacterial activity of several antiseptics.
Topics: Adolescent; Adult; Cross Infection; Disinfectants; Escherichia coli; Female; Forearm; Hand Disinfect | 2004 |
Comparative efficacy of hand hygiene agents in the reduction of bacteria and viruses.
Topics: Adult; Benzethonium; Chlorhexidine; Cross Infection; Disinfectants; Hand Disinfection; Humans; Infec | 2005 |
Triclosan-loaded poloxamine micelles for enhanced topical antibacterial activity against biofilm.
Topics: Anti-Infective Agents, Local; Biofilms; Cross Infection; Drug Stability; Enterococcus faecalis; Huma | 2008 |
Impact of preoperative screening for meticillin-resistant Staphylococcus aureus by real-time polymerase chain reaction in patients undergoing cardiac surgery.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Antibiotic Prophylaxis; Carrier State; Cohort S | 2008 |
The appropriate testing methods for OR Scrub?
Topics: Cross Infection; Hand Disinfection; Humans; Serratia marcescens; Triclosan | 1984 |
Serratia marcescens contamination of antiseptic soap containing triclosan: implications for nosocomial infection.
Topics: Candida; Chlorhexidine; Cross Infection; Drug Contamination; Drug Resistance, Microbial; Escherichia | 1984 |
Newborn conjunctivitis associated with triclosan 0.5% antiseptic intrinsically contaminated with Serratia marcescens.
Topics: Conjunctivitis, Bacterial; Cross Infection; Drug Contamination; Humans; Infant, Newborn; Infection C | 1995 |
Use of 0.3% triclosan (Bacti-Stat) to eradicate an outbreak of methicillin-resistant Staphylococcus aureus in a neonatal nursery.
Topics: Bacteriological Techniques; Cross Infection; Disease Outbreaks; Guidelines as Topic; Hand Disinfecti | 1995 |
Successful control of endemic MRSA in a cardiothoracic surgical unit.
Topics: Carrier State; Coronary Care Units; Cross Infection; Humans; Incidence; Methicillin Resistance; New | 1990 |
Triclosan: Safe or unsafe?
Topics: Cross Infection; Humans; Phenyl Ethers; Soaps; Surface-Active Agents; Triclosan | 1985 |