Page last updated: 2024-11-05

triclosan and Health Care Associated Infection

triclosan has been researched along with Health Care Associated Infection in 17 studies

Research Excerpts

ExcerptRelevanceReference
"Triclosan is a widely accepted antimicrobial ingredient because of its safety and antimicrobial efficacy."2.41Triclosan: a review of effectiveness and safety in health care settings. ( Jampani, HB; Jones, RD; Lee, AS; Newman, JL, 2000)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's3 (17.65)18.2507
2000's8 (47.06)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dittmann, K1
Schmidt, T1
Müller, G1
Cuny, C1
Holtfreter, S1
Troitzsch, D1
Pfaff, P1
Hübner, NO1
Lanini, S1
D'Arezzo, S1
Puro, V1
Martini, L1
Imperi, F1
Piselli, P1
Montanaro, M1
Paoletti, S1
Visca, P1
Ippolito, G1
Boyce, JM1
Dupont, HL1
Massaro, J1
Sack, D1
Schaffner, DW1
Marchetti, MG1
Kampf, G1
Finzi, G1
Salvatorelli, G1
Worthington, T1
Elliott, TS1
Messager, S1
Goddard, PA1
Dettmar, PW1
Maillard, JY1
Sickbert-Bennett, EE1
Weber, DJ1
Gergen-Teague, MF1
Sobsey, MD1
Samsa, GP1
Rutala, WA1
Seal, LA1
Rizer, RL1
Maas-Irslinger, R1
Chiappetta, DA1
Degrossi, J1
Teves, S1
D'Aquino, M1
Bregni, C1
Sosnik, A1
Jog, S1
Cunningham, R1
Cooper, S1
Wallis, M1
Marchbank, A1
Vasco-Knight, P1
Jenks, PJ1
Barry, MA1
Craven, DE1
Goularte, TA1
Lichtenberg, DA1
McNaughton, M1
Mazinke, N1
Thomas, E1
Zafar, AB1
Butler, RC1
Reese, DJ1
Gaydos, LA1
Mennonna, PA1
Jones, RD1
Jampani, HB1
Newman, JL1
Lee, AS1
Brady, LM1
Thomson, M1
Palmer, MA1
Harkness, JL1
Gravens, DL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Residual Effect of Chlorhexidine 2% / Isopropyl Alcohol 70% Compared to Triclosan 1% / Isopropyl Alcohol 70%[NCT01762904]Phase 3135 participants (Actual)Interventional2013-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Detect Presence of Allergy or Skin Reaction by the Antiseptic Application

"135 units of measurement to test two antiseptics and two controls. Principal unit of measurement: four determinations of bacterial counts in a subject for antiseptics and controls to test each of the application sites.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 2% chlorhexidine in 70% isopropyl alcohol and 1% triclosan in 70% isopropyl alcohol, Deionized water redistilled and Scrub the skin without prior application of any substance was tested. We prepared four skin's areas of 25 cm2, two in each forearm. The solution remained on the skin for 60s, 3h and 24h.~Presence of allergy or any skin reaction at 24 hours after the antiseptic application." (NCT01762904)
Timeframe: 24 hours

Interventionparticipants (Median)
Whole Group of 135 Units of Measurement0

Evaluate the Effect on the Skin Flora Application Process of Antiseptics by Sterile Swab

"135 units of measurement to test two controls. Principal unit of measurement: four determinations of bacterial counts in a subject for antiseptics and controls to test each of the application sites.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. Deionized water redistilled (Control 2: Control with scrub) and Scrub the skin without prior application of any substance (Control1: Control without scrub) was tested. Were prepared two skin's areas of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hrs

Intervention(CFU/cm2) (Median)
Control 1: without scrub 0 hControl 2: scrub with Deionized water redisti 0 hControl 1: without scrub 3 hControl 2: scrub with Deionized water redisti 3 hControl 1: without scrub 24 hControl 2: scrub with Deionized water redisti 24 h
Whole Group of 135 Units of Measurement4802162889628896

Evaluate the Residual Effect of Chlorhexidine 2% / Isopropyl Alcohol 70% Administered Topically

"135 determinations to evaluate residual effect of 2% chlorhexidine in 70% isopropyl alcohol.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 2% chlorhexidine in 70% isopropyl alcohol was tested. Were prepared the skin area of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h, everyone on different days.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hours

Intervention(CFU/cm2) (Median)
0 h3 h24 h
Whole Group of 135 Units of Measurement244824

Evaluate the Residual Effect of Triclosan 1% / Isopropyl Alcohol 70% Administered Topically.

"135 determinations to test 1% triclosan in 70% isopropyl alcohol.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 1% triclosan in 70% isopropyl alcohol was tested. Were prepared the skin area of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h, everyone on different days.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hours

Intervention(CFU/cm2) (Median)
0 h3 h24 h
Whole Group of 135 Units of Measurement484896

Reviews

1 review available for triclosan and Health Care Associated Infection

ArticleYear
Triclosan: a review of effectiveness and safety in health care settings.
    American journal of infection control, 2000, Volume: 28, Issue:2

    Topics: Anti-Infective Agents, Local; Biological Availability; Chemistry, Pharmaceutical; Chlorhexidine; Cro

2000

Trials

2 trials available for triclosan and Health Care Associated Infection

ArticleYear
An expert panel report of a proposed scientific model demonstrating the effectiveness of antibacterial handwash products.
    American journal of infection control, 2012, Volume: 40, Issue:8

    Topics: Anti-Infective Agents, Local; Chlorhexidine; Cross Infection; Cross-Over Studies; Cucumis melo; Dose

2012
A unique water optional health care personnel handwash provides antimicrobial persistence and residual effects while decreasing the need for additional products.
    American journal of infection control, 2005, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Chlorhexidine; Cross Infection; Ethanol; Fema

2005

Other Studies

14 other studies available for triclosan and Health Care Associated Infection

ArticleYear
Susceptibility of livestock-associated methicillin-resistant
    Antimicrobial resistance and infection control, 2019, Volume: 8

    Topics: Animals; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Community-Acquired Infections; Cro

2019
Molecular epidemiology of a Pseudomonas aeruginosa hospital outbreak driven by a contaminated disinfectant-soap dispenser.
    PloS one, 2011, Feb-16, Volume: 6, Issue:2

    Topics: Clinical Audit; Cohort Studies; Cross Infection; Disease Outbreaks; Disinfectants; Equipment Contami

2011
Evaluation of the bactericidal effect of five products for surgical hand disinfection according to prEN 12054 and prEN 12791.
    The Journal of hospital infection, 2003, Volume: 54, Issue:1

    Topics: 1-Propanol; Alcohols; Bacteria; Chlorhexidine; Colony Count, Microbial; Cross Infection; Disinfectan

2003
B4 Hand Hygienic Advanced Skin Protection(TM)-a handy adjunct in the prevention of cross-infection?
    The Journal of hospital infection, 2003, Volume: 55, Issue:2

    Topics: Anti-Infective Agents, Local; Attitude of Health Personnel; Cross Infection; Dermatologic Agents; Gu

2003
Comparison of two in vivo and two ex vivo tests to assess the antibacterial activity of several antiseptics.
    The Journal of hospital infection, 2004, Volume: 58, Issue:2

    Topics: Adolescent; Adult; Cross Infection; Disinfectants; Escherichia coli; Female; Forearm; Hand Disinfect

2004
Comparative efficacy of hand hygiene agents in the reduction of bacteria and viruses.
    American journal of infection control, 2005, Volume: 33, Issue:2

    Topics: Adult; Benzethonium; Chlorhexidine; Cross Infection; Disinfectants; Hand Disinfection; Humans; Infec

2005
Triclosan-loaded poloxamine micelles for enhanced topical antibacterial activity against biofilm.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 69, Issue:2

    Topics: Anti-Infective Agents, Local; Biofilms; Cross Infection; Drug Stability; Enterococcus faecalis; Huma

2008
Impact of preoperative screening for meticillin-resistant Staphylococcus aureus by real-time polymerase chain reaction in patients undergoing cardiac surgery.
    The Journal of hospital infection, 2008, Volume: 69, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Antibiotic Prophylaxis; Carrier State; Cohort S

2008
The appropriate testing methods for OR Scrub?
    Infection control : IC, 1984, Volume: 5, Issue:12

    Topics: Cross Infection; Hand Disinfection; Humans; Serratia marcescens; Triclosan

1984
Serratia marcescens contamination of antiseptic soap containing triclosan: implications for nosocomial infection.
    Infection control : IC, 1984, Volume: 5, Issue:9

    Topics: Candida; Chlorhexidine; Cross Infection; Drug Contamination; Drug Resistance, Microbial; Escherichia

1984
Newborn conjunctivitis associated with triclosan 0.5% antiseptic intrinsically contaminated with Serratia marcescens.
    The Canadian journal of infection control : the official journal of the Community & Hospital Infection Control Association-Canada = Revue canadienne de prevention des infections, 1995,Spring, Volume: 10, Issue:1

    Topics: Conjunctivitis, Bacterial; Cross Infection; Drug Contamination; Humans; Infant, Newborn; Infection C

1995
Use of 0.3% triclosan (Bacti-Stat) to eradicate an outbreak of methicillin-resistant Staphylococcus aureus in a neonatal nursery.
    American journal of infection control, 1995, Volume: 23, Issue:3

    Topics: Bacteriological Techniques; Cross Infection; Disease Outbreaks; Guidelines as Topic; Hand Disinfecti

1995
Successful control of endemic MRSA in a cardiothoracic surgical unit.
    The Medical journal of Australia, 1990, Mar-05, Volume: 152, Issue:5

    Topics: Carrier State; Coronary Care Units; Cross Infection; Humans; Incidence; Methicillin Resistance; New

1990
Triclosan: Safe or unsafe?
    Infection control : IC, 1985, Volume: 6, Issue:6

    Topics: Cross Infection; Humans; Phenyl Ethers; Soaps; Surface-Active Agents; Triclosan

1985