Page last updated: 2024-11-05

triclosan and Dental Caries

triclosan has been researched along with Dental Caries in 38 studies

Dental Caries: Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.

Research Excerpts

ExcerptRelevanceReference
" Triclosan is an antibacterial agent with low toxicity, which, along with a copolymer for aiding retention, can be added to toothpastes to reduce plaque and gingivitis (inflammation of the gums)."4.89Triclosan/copolymer containing toothpastes for oral health. ( Lamont, T; Riley, P, 2013)
"The retention of triclosan in dental plaque was significantly higher with Total as compared with other dentifrices 2 hours post brushing."2.67Recent advances in plaque, gingivitis, tartar and caries prevention technology. ( Afflitto, J; Gaffar, A; Herles, S; Kruger, I; Nabi, N; Olsen, S, 1994)
"Triclosan is a broad-spectrum antibacterial agent, marketed for use in oral products."2.43Advanced oral antibacterial/anti-inflammatory technology: A comprehensive review of the clinical benefits of a triclosan/copolymer/fluoride dentifrice. ( Davies, RM; DeVizio, W; Panagakos, FS; Petrone, ME; Proskin, HM; Volpe, AR, 2005)
"Xerostomia was assessed by questioning participants."1.42Antiseptic mouthwashes could worsen xerostomia in patients taking polypharmacy. ( Chevalier, M; Lamure, J; Pouyssegur-Rougier, V; Precheur, I; Sakarovitch, C, 2015)
" These included fluoride bioavailability tests, enamel lesion de- and remineralisation studies ('pH-cycling') and in situ caries studies."1.29The caries preventive effect of a fluoride dentifrice containing Triclosan and zinc citrate, a compilation of in vitro and in situ studies. ( ten Cate, JM, 1993)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19906 (15.79)18.7374
1990's13 (34.21)18.2507
2000's11 (28.95)29.6817
2010's7 (18.42)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Nogueira, C1
Mussi, L1
Baby, AR1
Zupeli, R1
Magalhães, WV1
Riley, P1
Lamont, T1
Randall, JP1
Seow, WK1
Walsh, LJ1
Chevalier, M1
Sakarovitch, C1
Precheur, I1
Lamure, J1
Pouyssegur-Rougier, V1
Lobos, O1
Padilla, A1
Padilla, C1
DeVizio, W4
Rodrigues, JA1
Lussi, A1
Seemann, R1
Neuhaus, KW1
García-Godoy, F1
Dibart, S1
Zhang, YP1
DE VECCHIS, B1
FISCHER, G1
BERGGREN, H1
HOFFMANN-AXTHELM, W1
Kulkarni, VV1
Damle, SG1
Finney, M1
Walker, JT1
Marsh, PD2
Brading, MG1
KROSCHEL, WP1
Wicht, MJ1
Haak, R1
Kneist, S1
Noack, MJ1
Panagakos, FS1
Volpe, AR6
Petrone, ME6
Davies, RM3
Proskin, HM4
Cao, HZ1
Wang, S1
Pan, Y1
Rana, R1
Itthagarun, A1
King, NM1
Hawley, GM1
Hamilton, FA1
Worthington, HV1
Holloway, PJ1
Davies, TG1
Blinkhorn, AS1
Gaffar, A3
Afflitto, J2
Nabi, N3
Herles, S1
Kruger, I1
Olsen, S1
ten Cate, JM1
Roberts, AJ1
Bouwsma, OJ1
Mann, J2
Karniel, C1
Triol, CW2
Sintes, JL2
Garcia, L2
Feller, RP1
Kiger, RD1
Saunders, KA1
Greenman, J1
McKenzie, C1
Vered, Y1
Babayof, I1
Sintes, J1
Stewart, B1
De Vizio, W1
McCool, JJ1
Prencipe, M1
Städtler, P1
Höller, H1
Mellberg, JR1
Blake-Haskins, J1
Petrou, ID1
Grote, NE1
Lindhe, J1
Mukerjee, C1
Schmid, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of a Toothpaste Containing 0.3% Triclosan in the Maintenance Phase of Peri-implantitis Treatment.[NCT03191721]Phase 3102 participants (Actual)Interventional2010-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for triclosan and Dental Caries

ArticleYear
Triclosan/copolymer containing toothpastes for oral health.
    The Cochrane database of systematic reviews, 2013, Dec-05, Issue:12

    Topics: Anti-Infective Agents, Local; Dental Calculus; Dental Caries; Dental Plaque; Gingivitis; Humans; Ora

2013
Prevention of crown and root caries in adults.
    Periodontology 2000, 2011, Volume: 55, Issue:1

    Topics: Adult; Anti-Infective Agents, Local; Antimicrobial Cationic Peptides; Biofilms; Cariostatic Agents;

2011
Advanced oral antibacterial/anti-inflammatory technology: A comprehensive review of the clinical benefits of a triclosan/copolymer/fluoride dentifrice.
    The Journal of clinical dentistry, 2005, Volume: 16 Suppl

    Topics: Anti-Infective Agents, Local; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Clinical Trials as

2005
A review of plaque, gingivitis, calculus and caries clinical efficacy studies with a dentifrice containing triclosan and PVM/MA Copolymer.
    The Journal of clinical dentistry, 1993, Volume: 4 Spec No

    Topics: Adult; Clinical Trials as Topic; Dental Calculus; Dental Caries; Dental Plaque; Dentifrices; Double-

1993
Antimicrobial strategies in the prevention of dental caries.
    Caries research, 1993, Volume: 27 Suppl 1

    Topics: Alkaloids; Anti-Infective Agents, Local; Bacterial Vaccines; Benzophenanthridines; Cetylpyridinium;

1993
Role of models in assessing new agents for caries prevention--non-fluoride systems.
    Advances in dental research, 1995, Volume: 9, Issue:3

    Topics: Animals; Anti-Infective Agents, Local; Calcium Phosphates; Cariostatic Agents; Caseins; Dental Carie

1995
The status, future, and problems of oral antiseptics.
    Current opinion in periodontology, 1996, Volume: 3

    Topics: Anti-Infective Agents, Local; Cetylpyridinium; Chlorhexidine; Dental Caries; Dental Plaque; Humans;

1996
Chemical agents for the control of plaque and plaque microflora: an overview.
    European journal of oral sciences, 1997, Volume: 105, Issue:5 Pt 2

    Topics: Anti-Infective Agents, Local; Bacteria; Bacterial Adhesion; Cariostatic Agents; Cations; Chemopreven

1997
The efficacy of a dentifrice with caries, plaque, gingivitis, tooth whitening and oral malodor benefits.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:2

    Topics: Cariostatic Agents; Complex Mixtures; Dental Caries; Dental Plaque; Dentifrices; Fluorides; Gingivit

2002
Toothpastes.
    International journal of clinical pharmacology, therapy, and toxicology, 1992, Volume: 30, Issue:5

    Topics: Alkaloids; Anti-Infective Agents; Benzophenanthridines; Dental Calculus; Dental Caries; Dental Plaqu

1992

Trials

9 trials available for triclosan and Dental Caries

ArticleYear
Comparative evaluation of efficacy of sodium fluoride, chlorhexidine and triclosan mouth rinses in reducing the mutans streptococci count in saliva : an in vivo study.
    Journal of the Indian Society of Pedodontics and Preventive Dentistry, 2003, Volume: 21, Issue:3

    Topics: Administration, Topical; Adolescent; Anti-Infective Agents, Local; Child; Chlorhexidine; Colony Coun

2003
A triclosan-containing compomer reduces Lactobacillus spp. predominant in advanced carious lesions.
    Dental materials : official publication of the Academy of Dental Materials, 2005, Volume: 21, Issue:9

    Topics: Acid Etching, Dental; Actinomyces; Adult; Anti-Infective Agents, Local; Colony Count, Microbial; Com

2005
Effects of dentifrices on artificial caries like lesions: an in vitro pH cycling study.
    International dental journal, 2007, Volume: 57, Issue:4

    Topics: Cariostatic Agents; Complex Mixtures; Dental Caries; Dentifrices; Fluorides; Humans; Hydrogen-Ion Co

2007
A 30-month study investigating the effect of adding triclosan/copolymer to a fluoride dentifrice.
    Caries research, 1995, Volume: 29, Issue:3

    Topics: Adolescent; Child; Confidence Intervals; Dental Caries; Dentifrices; DMF Index; Double-Blind Method;

1995
Recent advances in plaque, gingivitis, tartar and caries prevention technology.
    International dental journal, 1994, Volume: 44, Issue:1 Suppl 1

    Topics: Adsorption; Animals; Dental Calculus; Dental Caries; Dental Plaque; Dentifrices; Double-Blind Method

1994
Comparison of the clinical anticaries efficacy of a 1500 NaF silica-based dentifrice containing triclosan and a copolymer to a 1500 NaF silica-based dentifrice without those additional agents: a study on adults in Israel.
    The Journal of clinical dentistry, 1996, Volume: 7, Issue:4

    Topics: Adult; Aged; Analysis of Variance; Anti-Infective Agents, Local; Cariostatic Agents; Confidence Inte

1996
Comparison of the clinical anticaries efficacy of an 1100 NaF silica-based dentifrice containing triclosan and a copolymer to an 1100 NaF silica-based dentifrice without those additional agents: a study on adults in California.
    The Journal of clinical dentistry, 1996, Volume: 7, Issue:4

    Topics: Adult; Analysis of Variance; Anti-Infective Agents, Local; California; Cariostatic Agents; Confidenc

1996
The comparative anticaries efficacy of a dentifrice containing 0.3% triclosan and 2.0% copolymer in a 0.243% sodium fluoride/silica base and a dentifrice containing 0.243% sodium fluoride/silica base: a two-year coronal caries clinical trial on adults in
    The Journal of clinical dentistry, 2001, Volume: 12, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Cariostatic Agents; Complex Mixtures; Dental Caries; Dentifrices;

2001
Remineralization and demineralization in situ from a triclosan/co-polymer/fluoride dentifrice.
    Journal of dental research, 1991, Volume: 70, Issue:11

    Topics: Adult; Aged; Dental Caries; Dental Enamel; Dental Plaque; Dentifrices; Female; Humans; Male; Maleate

1991

Other Studies

19 other studies available for triclosan and Dental Caries

ArticleYear
Xylityl Sesquicaprylate Efficacy as an Antiseptic Ingredient for Oral Care Products (Mouthwash): An In Vitro Screening Investigation against Eight Microorganisms.
    Molecules (Basel, Switzerland), 2022, Dec-21, Volume: 28, Issue:1

    Topics: Anti-Infective Agents, Local; Dental Caries; Humans; Mouthwashes; Porphyromonas gingivalis; Triclosa

2022
Triclosan could boost fluoride in toothpastes.
    British dental journal, 2014, Volume: 216, Issue:3

    Topics: Anti-Infective Agents, Local; Dental Caries; Dental Plaque; Fluorides, Topical; Gingival Hemorrhage;

2014
Antibacterial activity of fluoride compounds and herbal toothpastes on Streptococcus mutans: an in vitro study.
    Australian dental journal, 2015, Volume: 60, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Chlorhexidine; Dental Caries; Fluorides; Humans

2015
Antiseptic mouthwashes could worsen xerostomia in patients taking polypharmacy.
    Acta odontologica Scandinavica, 2015, Volume: 73, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Betaine; Biofilms; Cetylpyridinium; Ch

2015
In vitro antimicrobial effect of bacteriocin PsVP-10 in combination with chlorhexidine and triclosan against Streptococcus mutans and Streptococcus sobrinus strains.
    Archives of oral biology, 2009, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Biofilms; Child; Chlorhexidine; Colony Count, Microbial; D

2009
The efficacy of a new dentifrice with caries, plaque, gingivitis, calculus, tooth whitening, and oral malodor benefits.
    The Journal of clinical dentistry, 2008, Volume: 19, Issue:3

    Topics: Complex Mixtures; Dental Calculus; Dental Caries; Dental Plaque; Dentifrices; Fluorides; Gingivitis;

2008
A dentifrice with multiple benefits.
    American journal of dentistry, 2011, Volume: 24 Spec No A

    Topics: Dental Caries; Dental Plaque; Dentin Sensitivity; Gingivitis; Humans; Maleates; Polyethylenes; Silic

2011
A multi-tasking dentifrice for the 21st century.
    American journal of dentistry, 2011, Volume: 24 Spec No A

    Topics: Cariostatic Agents; Dental Caries; Dental Plaque; Dentin Desensitizing Agents; Dentin Sensitivity; D

2011
[The scientific basis of dental caries].
    Osterreichische Zeitschrift fur Stomatologie, 1953, Volume: 50, Issue:10

    Topics: Dental Caries; Humans; Triclosan

1953
[The biological basis for a modern preparation of dental cavities].
    Zahnarztliche Rundschau, 1954, Jan-20, Volume: 63, Issue:2

    Topics: Dental Caries; Humans; Triclosan

1954
[The basis of dental caries prevention].
    Nordisk hygienisk tidskrift, 1958, Volume: 39, Issue:1-2

    Topics: Dental Care; Dental Caries; Humans; Triclosan

1958
[Roentgen diagnosis as basis in dental surgery].
    Deutsche Stomatologie, 1955, Volume: 5, Issue:4

    Topics: Dental Care; Dental Caries; Humans; Torso; Triclosan

1955
Antimicrobial effects of a novel Triclosan/zinc citrate dentifrice against mixed culture oral biofilms.
    International dental journal, 2003, Volume: 53, Issue:6 Suppl 1

    Topics: Anti-Infective Agents, Local; Biofilms; Cariostatic Agents; Chemistry, Pharmaceutical; Citric Acid;

2003
Organization of topical fluoride demonstration units on a regional basis.
    American journal of public health and the nation's health, 1950, Volume: 40, Issue:6

    Topics: Dental Caries; Fluorides; Fluorides, Topical; Humans; Organizations; Triclosan

1950
[An investigation of the clinical effect of the 0.3% Triclosan varnish on caries prevention of primary teeth].
    Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2007, Volume: 16, Issue:1

    Topics: Cariostatic Agents; Child, Preschool; Dental Caries; DMF Index; Humans; Tooth, Deciduous; Triclosan

2007
The caries preventive effect of a fluoride dentifrice containing Triclosan and zinc citrate, a compilation of in vitro and in situ studies.
    International dental journal, 1993, Volume: 43, Issue:4 Suppl 1

    Topics: Adult; Biological Availability; Citrates; Citric Acid; Dental Caries; Dental Enamel; Dentifrices; Dr

1993
Ecological effects of triclosan and triclosan monophosphate on defined mixed cultures of oral species grown in continuous culture.
    The Journal of antimicrobial chemotherapy, 2000, Volume: 45, Issue:4

    Topics: Anti-Infective Agents, Local; Bacteria; Colony Count, Microbial; Culture Media; Dental Caries; Mouth

2000
Triclosan/copolymer/fluoride dentifrices: a new technology for the prevention of plaque, calculus, gingivitis and caries.
    American journal of dentistry, 1990, Volume: 3 Spec No

    Topics: Dental Calculus; Dental Caries; Dental Plaque; Dentifrices; Drug Combinations; Gingivitis; Humans; M

1990
In vitro and in vivo studies on triclosan/PVM/MA copolymer/NaF combination as an anti-plaque agent.
    American journal of dentistry, 1989, Volume: 2 Spec No

    Topics: Animals; Dental Caries; Dental Plaque; Durapatite; Humans; Hydroxyapatites; Maleates; Microbial Sens

1989