triclosan has been researched along with Allergic Reaction in 18 studies
Excerpt | Relevance | Reference |
---|---|---|
" These studies were conducted to investigate the role of dermal exposure to triclosan, an endocrine-disrupting compound, on the hypersensitivity response to ovalbumin (OVA) in a murine model of asthma." | 7.79 | Exposure to triclosan augments the allergic response to ovalbumin in a mouse model of asthma. ( Anderson, KL; Anderson, SE; Franko, J; Hubbs, AF; Kashon, ML; Lukomska, E; Meade, BJ, 2013) |
" These studies were conducted to investigate the role of dermal exposure to triclosan, an endocrine-disrupting compound, on the hypersensitivity response to ovalbumin (OVA) in a murine model of asthma." | 3.79 | Exposure to triclosan augments the allergic response to ovalbumin in a mouse model of asthma. ( Anderson, KL; Anderson, SE; Franko, J; Hubbs, AF; Kashon, ML; Lukomska, E; Meade, BJ, 2013) |
"Triclosan is an anti-microbial chemical incorporated into products that are applied to the skin of healthcare workers." | 1.91 | Exposure to the anti-microbial chemical triclosan disrupts keratinocyte function and skin integrity in a model of reconstructed human epidermis. ( Anderson, SE; Baur, R; Kashon, M; Lukomska, E; Shane, HL; Weatherly, LM, 2023) |
"Current rhinitis was associated with the highest levels of triclosan, whereas no association was seen for current asthma." | 1.39 | Triclosan exposure and allergic sensitization in Norwegian children. ( Bertelsen, RJ; Calafat, AM; Carlsen, KH; London, SJ; Longnecker, MP; Lødrup Carlsen, KC; Løvik, M, 2013) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (44.44) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (5.56) | 29.6817 |
2010's | 5 (27.78) | 24.3611 |
2020's | 4 (22.22) | 2.80 |
Authors | Studies |
---|---|
Tang, N | 1 |
Wang, D | 1 |
Chen, X | 1 |
Zhang, M | 1 |
Lv, W | 1 |
Wang, X | 1 |
Baur, R | 3 |
Kashon, M | 2 |
Lukomska, E | 5 |
Weatherly, LM | 3 |
Shane, HL | 3 |
Anderson, SE | 5 |
Friend, SA | 1 |
Lin, MH | 1 |
Chiu, SY | 1 |
Ho, WC | 1 |
Chi, KH | 1 |
Liu, TY | 1 |
Wang, IJ | 1 |
Lee-Sarwar, K | 1 |
Hauser, R | 1 |
Calafat, AM | 2 |
Ye, X | 1 |
O'Connor, GT | 1 |
Sandel, M | 1 |
Bacharier, LB | 1 |
Zeiger, RS | 1 |
Laranjo, N | 1 |
Gold, DR | 1 |
Weiss, ST | 1 |
Litonjua, AA | 1 |
Savage, JH | 1 |
Marshall, NB | 1 |
Nayak, AP | 1 |
Long, CM | 1 |
Hettick, JM | 1 |
Hampton, T | 1 |
Bertelsen, RJ | 1 |
Longnecker, MP | 1 |
Løvik, M | 1 |
Carlsen, KH | 1 |
London, SJ | 1 |
Lødrup Carlsen, KC | 1 |
Franko, J | 1 |
Kashon, ML | 1 |
Anderson, KL | 1 |
Hubbs, AF | 1 |
Meade, BJ | 1 |
LIEBERMAN, A | 1 |
McELROY, WT | 1 |
WESTON, TE | 1 |
SCHEIFFARTH, F | 1 |
ROBINSON, JP | 1 |
SAWYER, M | 1 |
NAJJAR, VA | 1 |
ANDERSON, JR | 1 |
SPAIN, WC | 1 |
ROSTON, EH | 1 |
MAYER, RL | 1 |
Levy, SB | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Residual Effect of Chlorhexidine 2% / Isopropyl Alcohol 70% Compared to Triclosan 1% / Isopropyl Alcohol 70%[NCT01762904] | Phase 3 | 135 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"135 units of measurement to test two antiseptics and two controls. Principal unit of measurement: four determinations of bacterial counts in a subject for antiseptics and controls to test each of the application sites.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 2% chlorhexidine in 70% isopropyl alcohol and 1% triclosan in 70% isopropyl alcohol, Deionized water redistilled and Scrub the skin without prior application of any substance was tested. We prepared four skin's areas of 25 cm2, two in each forearm. The solution remained on the skin for 60s, 3h and 24h.~Presence of allergy or any skin reaction at 24 hours after the antiseptic application." (NCT01762904)
Timeframe: 24 hours
Intervention | participants (Median) |
---|---|
Whole Group of 135 Units of Measurement | 0 |
"135 units of measurement to test two controls. Principal unit of measurement: four determinations of bacterial counts in a subject for antiseptics and controls to test each of the application sites.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. Deionized water redistilled (Control 2: Control with scrub) and Scrub the skin without prior application of any substance (Control1: Control without scrub) was tested. Were prepared two skin's areas of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hrs
Intervention | (CFU/cm2) (Median) | |||||
---|---|---|---|---|---|---|
Control 1: without scrub 0 h | Control 2: scrub with Deionized water redisti 0 h | Control 1: without scrub 3 h | Control 2: scrub with Deionized water redisti 3 h | Control 1: without scrub 24 h | Control 2: scrub with Deionized water redisti 24 h | |
Whole Group of 135 Units of Measurement | 480 | 216 | 288 | 96 | 288 | 96 |
"135 determinations to evaluate residual effect of 2% chlorhexidine in 70% isopropyl alcohol.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 2% chlorhexidine in 70% isopropyl alcohol was tested. Were prepared the skin area of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h, everyone on different days.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hours
Intervention | (CFU/cm2) (Median) | ||
---|---|---|---|
0 h | 3 h | 24 h | |
Whole Group of 135 Units of Measurement | 24 | 48 | 24 |
"135 determinations to test 1% triclosan in 70% isopropyl alcohol.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 1% triclosan in 70% isopropyl alcohol was tested. Were prepared the skin area of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h, everyone on different days.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hours
Intervention | (CFU/cm2) (Median) | ||
---|---|---|---|
0 h | 3 h | 24 h | |
Whole Group of 135 Units of Measurement | 48 | 48 | 96 |
1 review available for triclosan and Allergic Reaction
Article | Year |
---|---|
Maternal bisphenol A and triclosan exposure and allergic diseases in childhood: a meta-analysis of cohort studies.
Topics: Benzhydryl Compounds; Child; Cohort Studies; Female; Humans; Hypersensitivity; Maternal Exposure; Pr | 2022 |
17 other studies available for triclosan and Allergic Reaction
Article | Year |
---|---|
Exposure to the anti-microbial chemical triclosan disrupts keratinocyte function and skin integrity in a model of reconstructed human epidermis.
Topics: Animals; Cell Differentiation; Cytokines; Epidermis; Humans; Hypersensitivity; Keratinocytes; Mice; | 2023 |
Exposure to the anti-microbial chemical triclosan disrupts keratinocyte function and skin integrity in a model of reconstructed human epidermis.
Topics: Animals; Cell Differentiation; Cytokines; Epidermis; Humans; Hypersensitivity; Keratinocytes; Mice; | 2023 |
Exposure to the anti-microbial chemical triclosan disrupts keratinocyte function and skin integrity in a model of reconstructed human epidermis.
Topics: Animals; Cell Differentiation; Cytokines; Epidermis; Humans; Hypersensitivity; Keratinocytes; Mice; | 2023 |
Exposure to the anti-microbial chemical triclosan disrupts keratinocyte function and skin integrity in a model of reconstructed human epidermis.
Topics: Animals; Cell Differentiation; Cytokines; Epidermis; Humans; Hypersensitivity; Keratinocytes; Mice; | 2023 |
Topical Application of the Antimicrobial Agent Triclosan Induces NLRP3 Inflammasome Activation and Mitochondrial Dysfunction.
Topics: Animals; Anti-Infective Agents; Carrier Proteins; Hypersensitivity; Inflammasomes; Macrophages; Memb | 2020 |
Effect of triclosan on the pathogenesis of allergic diseases among children.
Topics: Asthma; Child; Child, Preschool; Dermatitis, Atopic; Humans; Hypersensitivity; Immunoglobulin E; Mal | 2022 |
Prenatal and early-life triclosan and paraben exposure and allergic outcomes.
Topics: Child, Preschool; Cross-Sectional Studies; Female; Humans; Hypersensitivity; Longitudinal Studies; M | 2018 |
Topical application of the anti-microbial chemical triclosan induces immunomodulatory responses through the S100A8/A9-TLR4 pathway.
Topics: Administration, Topical; Allergens; Animals; Anti-Infective Agents; Antibodies, Blocking; Calgranuli | 2017 |
Research provides new insights on how hygiene affects asthma and allergies.
Topics: Anti-Infective Agents; Asthma; Bacteria; Environmental Exposure; Fungi; Humans; Hygiene; Hypersensit | 2011 |
Triclosan exposure and allergic sensitization in Norwegian children.
Topics: Allergens; Asthma; Child; Environmental Exposure; Female; Humans; Hypersensitivity; Immunoglobulin E | 2013 |
Exposure to triclosan augments the allergic response to ovalbumin in a mouse model of asthma.
Topics: Administration, Cutaneous; Animals; Anti-Infective Agents; Asthma; Bronchoalveolar Lavage Fluid; Dis | 2013 |
The allergic basis of Fiedler's myocarditis; with discussion of two case histories.
Topics: Humans; Hypersensitivity; Immune System Diseases; Myocarditis; Triclosan | 1957 |
The etiology of anaphylactic shock; the basis for drug therapy in allergic individuals.
Topics: Anaphylaxis; Humans; Hypersensitivity; Immune System Diseases; Triclosan | 1959 |
AN ALLERGIC BASIS FOR NON-SPECIFIC URETHRITIS.
Topics: Antigen-Antibody Reactions; Humans; Hypersensitivity; Skin Tests; Triclosan; Urethritis | 1965 |
[The pathophysiological basis of the allergy doctrine].
Topics: Hypersensitivity; Immune System Diseases; Triclosan | 1955 |
Theoretical basis for allergic reations.
Topics: Humans; Hypersensitivity; Immune System Diseases; Triclosan | 1962 |
The allergic basis of certain otorhinolaryngologic complaints.
Topics: Humans; Hypersensitivity; Immune System Diseases; Triclosan | 1951 |
The case for histamine as the basis of allergic reactions; attempts at its neutralization.
Topics: Histamine; Humans; Hypersensitivity; Immune System Diseases; Triclosan | 1951 |
The experimental basis of antihistaminic therapy.
Topics: Anaphylaxis; Histamine; Hypersensitivity; Immune System Diseases; Otolaryngology; Triclosan | 1949 |
Antibacterial household products: cause for concern.
Topics: Anti-Infective Agents, Local; Bacteria; Bacterial Infections; Drug Resistance, Microbial; Household | 2001 |