Page last updated: 2024-08-23

triciribine phosphate and Neoplasms

triciribine phosphate has been researched along with Neoplasms in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, C; He, Q; Jiang, Z; Ou, X; Sun, C; Zhang, H1
Cheng, JQ; Coppola, D; Cubitt, CL; Frost, TJ; Garrett, CR; Lush, RM; Neuger, AM; Sebti, SM; Sullivan, DM; Wenham, RM1
Drach, JC; Rosania, GR; Shedden, K; Townsend, LB1
Ajani, JA; Benjamin, RS; Bodey, GP; Burgess, MA; Feun, LG; Krakoff, I; Lu, K; McKelvey, E; Savaraj, N; Yap, BS1
Casper, ES; Cassidy, C; Godwin, TA; Mittelman, A; Young, CW1
Bogden, AE; Cobb, WR; Griffin, TW; Kelton, DE; LePage, DJ; Reich, SD1
Baker, LH; Haas, CD; Samson, MK; Schilcher, RB; Young, JD1
Basseches, PJ; Kroschel, DM; Kvols, LK; O'Connell, MJ; Powis, G; Richardson, RL1

Trials

2 trial(s) available for triciribine phosphate and Neoplasms

ArticleYear
Phase I pharmacokinetic and pharmacodynamic study of triciribine phosphate monohydrate, a small-molecule inhibitor of AKT phosphorylation, in adult subjects with solid tumors containing activated AKT.
    Investigational new drugs, 2011, Volume: 29, Issue:6

    Topics: Acenaphthenes; Adult; Biopsy; Dose-Response Relationship, Drug; Humans; Mutation; Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Ribonucleotides; Treatment Outcome

2011
Phase I study of tricyclic nucleoside phosphate.
    Cancer treatment reports, 1983, Volume: 67, Issue:2

    Topics: Acenaphthenes; Adult; Aged; Blood Glucose; Bone Marrow; Calcium; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Parenteral; Liver; Male; Middle Aged; Nausea; Neoplasms; Phosphorus; Ribonucleotides

1983

Other Studies

6 other study(ies) available for triciribine phosphate and Neoplasms

ArticleYear
Lower endogenous p53 levels and degradation of AKT protein contribute to potent suppression of the new antibiotic Xiakemycin A on tumor cells.
    Oncology reports, 2018, Volume: 39, Issue:6

    Topics: A549 Cells; Acenaphthenes; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; HeLa Cells; Hep G2 Cells; Humans; Male; MCF-7 Cells; Naphthoquinones; Neoplasms; Phosphorylation; Proteolysis; Proto-Oncogene Proteins c-akt; Ribonucleotides; Tumor Suppressor Protein p53

2018
A rational approach to personalized anticancer therapy: chemoinformatic analysis reveals mechanistic gene-drug associations.
    Pharmaceutical research, 2003, Volume: 20, Issue:6

    Topics: Acenaphthenes; Adenosine Kinase; Antineoplastic Agents; Biotransformation; Catalysis; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Medical Informatics; Neoplasms; Oligonucleotides; Ribonucleotides

2003
Phase I study of tricyclic nucleoside phosphate using a five-day continuous infusion schedule.
    Cancer research, 1984, Volume: 44, Issue:8

    Topics: Acenaphthenes; Adult; Aged; Anemia; Antineoplastic Agents; Blood Platelets; Drug Evaluation; Female; Granulocytes; Humans; Hyperglycemia; Infusions, Parenteral; Leukocytes; Male; Middle Aged; Neoplasms; Ribonucleotides

1984
Activity of two phase I drugs, homoharringtonine and tricyclic nucleotide, against surgical explants of human tumors in the 6-day subrenal capsule assay.
    Cancer treatment reports, 1983, Volume: 67, Issue:2

    Topics: Acenaphthenes; Alkaloids; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Harringtonines; Homoharringtonine; Humans; Kidney; Mice; Neoplasm Transplantation; Neoplasms; Ribonucleotides

1983
Phase I evaluation and clinical pharmacology of tricyclic nucleoside 5'-phosphate using a weekly intravenous regimen.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Acenaphthenes; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Humans; Injections, Intravenous; Kinetics; Liver; Male; Middle Aged; Neoplasms; Ribonucleotides; Thrombocytopenia

1986
Disposition of tricyclic nucleoside-5'-monophosphate in blood and plasma of patients during phase I and II clinical trials.
    Cancer treatment reports, 1986, Volume: 70, Issue:3

    Topics: Acenaphthenes; Antineoplastic Agents; Drug Evaluation; Erythrocytes; Half-Life; Humans; Kinetics; Neoplasms; Ribonucleotides

1986