trichodermamide-b has been researched along with Lung-Neoplasms* in 1 studies
1 other study(ies) available for trichodermamide-b and Lung-Neoplasms
Article | Year |
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The isolation, structure determination and cytotoxicity of the new fungal metabolite, trichodermamide C.
Chemical investigations of a culture broth from the endophytic fungus Eupenicillium sp. afforded the new modified dipeptide trichodermamide C 1. The structure of 1 was established following the analysis of NMR, UV, IR, MS and X-ray diffraction data. Trichodermamide C was shown by high content screening to display cytotoxicity towards the human colorectal carcinoma HCT116 and human lung carcinoma A549 with IC(50) values of 0.68 and 4.28microg/ml, respectively. Topics: Antineoplastic Agents; Colorectal Neoplasms; Dipeptides; Diterpenes; Eurotiales; Humans; Inhibitory Concentration 50; Lung Neoplasms; Penicillium; Spectrum Analysis; X-Ray Diffraction | 2008 |