Page last updated: 2024-08-17

trichloroethylene and Liver Neoplasms

trichloroethylene has been researched along with Liver Neoplasms in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (20.51)	18.7374
1990's	7 (17.95)	18.2507
2000's	14 (35.90)	29.6817
2010's	9 (23.08)	24.3611
2020's	1 (2.56)	2.80

Authors

Authors	Studies
Abdraboh, ME; Amer, ME; El-Missiry, MA; Elhamed, DSA; Othman, AI; Taha, AN	1
Chen, T; Fei, R; Jiang, Y; Li, J; Tao, Y; Wang, J; Zhou, X; Zhou, Z	1
Hansen, J; Kauppinen, T; Kjaerheim, K; Kyyrönen, P; Martinsen, JI; Pukkala, E; Sparén, P; Straif, K; Tryggvadottir, L; Vlaanderen, J; Weiderpass, E	1
Andersson, K; Anttila, A; Bryngelsson, IL; Hansen, J; McLaughlin, JK; Olsen, JH; Pukkala, E; Raaschou-Nielsen, O; Sallmén, M; Seldén, AI	1
McNeil, C	1
Clarke, CA; Deapen, D; Gomez, SL; McKinley, M; Press, DJ	1
Hu, W; Huang, H; Jones, DP; Kim, S; Lan, Q; Li, L; Pennell, KD; Purdue, MP; Reiss, B; Rothman, N; Smith, M; Tang, X; Uppal, K; Vermeulen, R; Walker, DI; Zhang, L	1
Chen, J; Chen, T; Jiang, Y; Li, J; Tong, J; Yue, C; Zhang, H	1
Corton, JC	1
Chang, YY; Chen, CH; Lee, LJ; Liou, SH; Wang, JD	1
Jinot, J; Scott, CS	1
Bull, RJ; Cheng, RS; Lingohr, MK; Orner, GA; Sasser, LB; Stauber, AJ; Stillwell, L; Thrall, BD	1
Wong, O	1
Caldwell, JC; Keshava, N	2
Chiu, WA; Scott, CS	1
Babich, MA; Cook, JC; David, RM; DeLuca, JG; Fenner-Crisp, PA; Klaunig, JE; McKee, RH; Peters, JM; Roberts, RA	1
Alexander, DD; Basu, R; Kelsh, MA; Mandel, JH; Mink, PJ; Weingart, M	1
Cao, J; Geng, C; Hu, C; Jiang, L; Zhang, X; Zhong, L	1
Paddle, GM	1
Quast, JF; Stott, WT; Watanabe, PG	1
Allen, BC; Fisher, JW	1
Abelson, PH	1
Fisher, JW	1
Bull, RJ; Larson, JL; Stevens, DK; Templin, M	1
Fenner-Crisp, PA	1
Anttila, A; Hemminki, K; Lynge, E	1
Bull, RJ	1
Chen, CW	1
Rudén, C	2
Siegel Scott, C; Wartenberg, D	1
Bolt, HM; Kunz, W; Laib, RJ; Stöckle, G	1
Bolt, HM; Laib, RJ; Stöckle, G	1
Van Duuren, BL	1
Breslin, P; Lloyd, JW; Moore, RM	1
Hampton, JA; Hartnett, JA; Klaunig, JE; Olson, MJ; Schafer, LD; Siglin, JC; Weghorst, CM	1
Dekant, W	1
Elcombe, CR	1

Reviews

11 review(s) available for trichloroethylene and Liver Neoplasms

Article	Year
Risk of cancer among workers exposed to trichloroethylene: analysis of three Nordic cohort studies. Journal of the National Cancer Institute, 2013, Jun-19, Volume: 105, Issue:12 Topics: Adenocarcinoma; Adult; Aged; Cohort Studies; Denmark; Esophageal Neoplasms; Female; Finland; Humans; Incidence; Kidney Neoplasms; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasms; Occupational Diseases; Proportional Hazards Models; Risk Assessment; Solvents; Sweden; Trichloroacetic Acid; Trichloroethylene; Uterine Cervical Neoplasms	2013
Evaluation of the role of peroxisome proliferator-activated receptor alpha (PPARalpha) in mouse liver tumor induction by trichloroethylene and metabolites. Critical reviews in toxicology, 2008, Volume: 38, Issue:10 Topics: Animals; Dichloroacetic Acid; Environmental Pollutants; Liver Neoplasms; Mice; Peroxisome Proliferator-Activated Receptors; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethylene	2008
Trichloroethylene and cancer: systematic and quantitative review of epidemiologic evidence for identifying hazards. International journal of environmental research and public health, 2011, Volume: 8, Issue:11 Topics: Causality; Global Health; Humans; Kidney Neoplasms; Liver Neoplasms; Lymphoma, Non-Hodgkin; Models, Statistical; Occupational Exposure; Solvents; Trichloroethylene	2011
Carcinogenicity of trichloroethylene: an epidemiologic assessment. Clinics in occupational and environmental medicine, 2004, Volume: 4, Issue:3 Topics: Humans; Liver Neoplasms; Neoplasms; Occupational Exposure; Occupations; Solvents; Trichloroethylene; Water Pollutants	2004
Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity. Environmental health perspectives, 2006, Volume: 114, Issue:9 Topics: Animals; Carcinogenicity Tests; Environmental Pollutants; Gene Expression Regulation; History, 21st Century; Humans; Liver Neoplasms; PPAR alpha; Risk Assessment; Signal Transduction; Trichloroethylene; United States; United States Environmental Protection Agency	2006
Trichloroethylene cancer epidemiology: a consideration of select issues. Environmental health perspectives, 2006, Volume: 114, Issue:9 Topics: Animals; Databases, Factual; Environmental Pollutants; History, 21st Century; Humans; Kidney Neoplasms; Liver Neoplasms; Lymphatic System; Meta-Analysis as Topic; Mortality; Neoplasms; Risk Assessment; Statistics as Topic; Trichloroethylene; United States; United States Environmental Protection Agency	2006
Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis. Environmental health perspectives, 2006, Volume: 114, Issue:9 Topics: Animals; Carcinogenicity Tests; Chloral Hydrate; Cysteine; Dichloroacetic Acid; Environmental Pollutants; History, 21st Century; Humans; Kidney Neoplasms; Liver Neoplasms; Risk Assessment; Risk Factors; Signal Transduction; Trichloroacetic Acid; Trichloroethylene; United States	2006
A meta-analysis of occupational trichloroethylene exposure and liver cancer. International archives of occupational and environmental health, 2007, Volume: 81, Issue:2 Topics: Case-Control Studies; Cohort Studies; Humans; Liver Neoplasms; Occupational Exposure; Trichloroethylene	2007
Organic solvents and cancer. Cancer causes & control : CCC, 1997, Volume: 8, Issue:3 Topics: Alcohol Drinking; Benzene; Biliary Tract Neoplasms; Carbon Tetrachloride; Carcinogens; China; Cohort Studies; Confounding Factors, Epidemiologic; Esophageal Neoplasms; Europe; Female; Hematologic Neoplasms; Humans; Leukemia; Liver Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methylene Chloride; Multiple Myeloma; Neoplasms; North America; Occupational Diseases; Occupational Exposure; Organic Chemicals; Risk Factors; Sexual Behavior; Smoking; Solvents; Tetrachloroethylene; Toluene; Trichloroethanes; Trichloroethylene; Uterine Cervical Neoplasms	1997
Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate. Environmental health perspectives, 2000, Volume: 108 Suppl 2 Topics: Animals; Carcinogens, Environmental; Dichloroacetic Acid; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mutagens; Risk Assessment; Trichloroacetic Acid; Trichloroethylene	2000
The use of mechanistic data and the handling of scientific uncertainty in carcinogen risk assessments. The trichloroethylene example. Regulatory toxicology and pharmacology : RTP, 2002, Volume: 35, Issue:1 Topics: Animals; Carcinogenicity Tests; Carcinogens; Dose-Response Relationship, Drug; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Risk Assessment; Sensitivity and Specificity; Solvents; Trichloroethylene	2002

Other Studies

28 other study(ies) available for trichloroethylene and Liver Neoplasms

Article	Year
Constant light exposure and/or pinealectomy increases susceptibility to trichloroethylene-induced hepatotoxicity and liver cancer in male mice. Environmental science and pollution research international, 2022, Volume: 29, Issue:40 Topics: Animals; Chemical and Drug Induced Liver Injury; Liver; Liver Neoplasms; Male; Melatonin; Mice; Pineal Gland; Pinealectomy; Solvents; Trichloroethylene	2022
Role of miR-182-5p overexpression in trichloroethylene-induced abnormal cell cycle functions in human HepG2 cells. Journal of toxicology and environmental health. Part A, 2019, Volume: 82, Issue:16 Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; MicroRNAs; Trichloroethylene	2019
Occupational exposure to trichloroethylene and perchloroethylene and the risk of lymphoma, liver, and kidney cancer in four Nordic countries. Occupational and environmental medicine, 2013, Volume: 70, Issue:6 Topics: Adult; Carcinogens; Cohort Studies; Europe; Female; Humans; Industry; Kidney Neoplasms; Liver Neoplasms; Logistic Models; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Neoplasms; Occupational Diseases; Occupational Exposure; Risk Factors; Solvents; Tetrachloroethylene; Trichloroethylene	2013
TCE, designated a known carcinogen, now the focus of ongoing research. Journal of the National Cancer Institute, 2013, Oct-16, Volume: 105, Issue:20 Topics: B-Lymphocytes; Breast Neoplasms, Male; Carcinogens; Environmental Exposure; Female; Humans; Immunoglobulin G; Immunoglobulin M; Kidney Neoplasms; Liver Neoplasms; Lymphocyte Count; Lymphoma, Non-Hodgkin; Male; Neoplasms; Occupational Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Trichloroethylene; United States; United States Environmental Protection Agency; Uterine Cervical Neoplasms; Water Supply	2013
Residential cancer cluster investigation nearby a Superfund Study Area with trichloroethylene contamination. Cancer causes & control : CCC, 2016, Volume: 27, Issue:5 Topics: California; Censuses; Environmental Exposure; Female; Hazardous Waste Sites; Humans; Incidence; Industry; Kidney Neoplasms; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; SEER Program; Solvents; Trichloroethylene	2016
High-resolution metabolomics of occupational exposure to trichloroethylene. International journal of epidemiology, 2016, Volume: 45, Issue:5 Topics: Adolescent; Adult; Case-Control Studies; China; Cross-Sectional Studies; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Mass Spectrometry; Metabolome; Metabolomics; Occupational Diseases; Occupational Exposure; Regression Analysis; Trichloroethylene; Young Adult	2016
The Role of miR-182-5p in Hepatocarcinogenesis of Trichloroethylene in Mice. Toxicological sciences : an official journal of the Society of Toxicology, 2017, 03-01, Volume: 156, Issue:1 Topics: Animals; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Proliferation; Crosses, Genetic; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Liver; Liver Neoplasms; Male; Mice; MicroRNAs; Neoplasm Proteins; Promoter Regions, Genetic; Random Allocation; Repressor Proteins; RNA, Neoplasm; Solvents; Trans-Activators; Trichloroethylene	2017
An estimation of the health impact of groundwater pollution caused by dumping of chlorinated solvents. The Science of the total environment, 2010, Feb-15, Volume: 408, Issue:6 Topics: Aged; Carcinogens, Environmental; Environmental Monitoring; Epidemiological Monitoring; Female; Fresh Water; Humans; Liver Neoplasms; Male; Middle Aged; Quality of Life; Risk Assessment; Risk Factors; Solvents; Taiwan; Trichloroethylene; Vinyl Chloride; Water Pollutants, Chemical	2010
Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene. Toxicology and applied pharmacology, 2002, Jul-01, Volume: 182, Issue:1 Topics: Animals; Blotting, Western; Dichloroacetic Acid; DNA, Neoplasm; Drug Interactions; Genes, jun; Genes, ras; Liver Neoplasms; Male; Mice; Mutation; Polymerase Chain Reaction; Random Allocation; Sequence Analysis, DNA; Solvents; Trichloroacetic Acid; Trichloroethylene	2002
PPARalpha and effects of TCE. Environmental health perspectives, 2007, Volume: 115, Issue:1 Topics: Animals; Carcinogens; Liver Neoplasms; PPAR alpha; Risk Assessment; Trichloroethylene	2007
Possible involvement of oxidative stress in trichloroethylene-induced genotoxicity in human HepG2 cells. Mutation research, 2008, Mar-29, Volume: 652, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Carcinoma, Hepatocellular; Deoxyguanosine; DNA Damage; Drug Evaluation, Preclinical; Glutathione; Humans; Lipid Peroxidation; Liver Neoplasms; Micronuclei, Chromosome-Defective; Mutagenicity Tests; Oxidative Stress; Solvents; Trichloroethylene; Tumor Cells, Cultured	2008
Incidence of liver cancer and trichloroethylene manufacture: joint study by industry and a cancer registry. British medical journal (Clinical research ed.), 1983, Mar-12, Volume: 286, Issue:6368 Topics: Chemical Industry; Humans; Liver Neoplasms; Male; Occupational Diseases; Registries; Trichloroethylene	1983
The pharmacokinetics and macromolecular interactions of trichloroethylene in mice and rats. Toxicology and applied pharmacology, 1982, Volume: 62, Issue:1 Topics: Alkylation; Animals; Carbon Radioisotopes; DNA; Dose-Response Relationship, Drug; Kinetics; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Species Specificity; Trichloroethylene	1982
Evaluating the risk of liver cancer in humans exposed to trichloroethylene using physiological models. Risk analysis : an official publication of the Society for Risk Analysis, 1993, Volume: 13, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Environmental Pollutants; Female; Humans; Liver Neoplasms; Male; Mice; Models, Biological; Rats; Risk Factors; Trichloroethylene	1993
Health risk assessment. Regulatory toxicology and pharmacology : RTP, 1993, Volume: 17, Issue:2 Pt 1 Topics: Animals; Carcinogenicity Tests; Carcinogens; Disease Models, Animal; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methylene Chloride; Mice; Neoplasms; Rats; Risk Factors; Tetrachloroethylene; Trichloroethylene; United States; United States Environmental Protection Agency	1993
Estimating the risks of liver and lung cancer in humans exposed to trichloroethylene using a physiological model. Toxicology letters, 1993, Volume: 68, Issue:1-2 Topics: Animals; Humans; Liver Neoplasms; Lung Neoplasms; Models, Biological; Rats; Risk Factors; Trichloroethylene	1993
The role of dichloroacetate in the hepatocarcinogenicity of trichloroethylene. Toxicology letters, 1993, Volume: 68, Issue:1-2 Topics: Animals; Dichloroacetic Acid; Liver Neoplasms; Mice; Mice, Inbred Strains; Rats; Trichloroethylene	1993
Regulatory implications: U.S. Environmental Protection Agency. Annals of the New York Academy of Sciences, 1996, Dec-27, Volume: 804 Topics: Animals; Carcinogens; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Microbodies; Tetrachloroethylene; Trichloroethylene; United States; United States Environmental Protection Agency	1996
Biologically based dose-response model for liver tumors induced by trichloroethylene. Environmental health perspectives, 2000, Volume: 108 Suppl 2 Topics: Animals; Carcinogens, Environmental; Dichloroacetic Acid; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Models, Biological; Risk Assessment; Trichloroacetic Acid; Trichloroethylene	2000
The use and evaluation of primary data in 29 trichloroethylene carcinogen risk assessments. Regulatory toxicology and pharmacology : RTP, 2001, Volume: 34, Issue:1 Topics: Animals; Carcinogens; Humans; Kidney Neoplasms; Liver Neoplasms; Mice; Rats; Risk Assessment; Toxicity Tests; Trichloroethylene	2001
Carcinogenicity of trichloroethylene. Environmental health perspectives, 2002, Volume: 110, Issue:1 Topics: Cohort Studies; Confounding Factors, Epidemiologic; Epidemiologic Studies; Female; Humans; Incidence; Kidney Neoplasms; Liver Neoplasms; Male; Risk Assessment; Solvents; Trichloroethylene; Uterine Cervical Neoplasms	2002
Vinyl chloride and trichloroethylene: comparison of alkylating effects of metabolites and induction of preneoplastic enzyme deficiencies in rat liver. Journal of cancer research and clinical oncology, 1979, Jun-08, Volume: 94, Issue:2 Topics: Adenosine; Adenosine Triphosphatases; Alkylation; Animals; Animals, Newborn; Chromatography, Ion Exchange; Cytidine; Female; Liver; Liver Neoplasms; Mitochondria, Liver; Rats; RNA; Trichloroethylene; Vinyl Chloride; Vinyl Compounds	1979
Induction of pre-malignant hepatic lesions: comparative effects of vinyl chloride and trichloroethylene [proceedings]. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1979, Issue:2 Topics: Animals; Animals, Newborn; Female; Liver Neoplasms; Neoplasms, Experimental; Precancerous Conditions; Rats; Trichloroethylene; Vinyl Chloride; Vinyl Compounds	1979
On the possible mechanism of carcinogenic action of vinyl chloride. Annals of the New York Academy of Sciences, 1975, Jan-31, Volume: 246 Topics: Alkylating Agents; Animals; Disulfiram; Hemangiosarcoma; Humans; Liver Neoplasms; Mice; Neoplasms; Rats; Trichloroethylene; Vinyl Chloride; Vinyl Compounds	1975
Background information on trichloroethylene. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1975, Volume: 17, Issue:9 Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Chemical Industry; Environmental Exposure; Female; Humans; Liver Neoplasms; Maximum Allowable Concentration; Mice; Neurologic Manifestations; Occupational Medicine; Pregnancy; Rats; Solvents; Substance-Related Disorders; Trichloroethylene	1975
Correlation between species and tissue sensitivity to chemical carcinogenesis in rodents and the induction of DNA synthesis. Progress in clinical and biological research, 1991, Volume: 369 Topics: Animals; Barbiturates; Carcinogens; Cell Division; DNA Replication; Female; Gasoline; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Mitotic Index; Organ Specificity; Phenobarbital; Rats; Rats, Inbred F344; Species Specificity; Trichloroethylene	1991
Metabolic conversion of tri- and tetrachloroethylene: formation and deactivation of genotoxic intermediates. Developments in toxicology and environmental science, 1986, Volume: 12 Topics: Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Escherichia coli; Liver; Liver Neoplasms; Rats; Salmonella typhimurium; Tetrachloroethylene; Trichloroethylene	1986
Species differences in carcinogenicity and peroxisome proliferation due to trichloroethylene: a biochemical human hazard assessment. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1985, Volume: 8 Topics: Animals; Biotransformation; Carcinogens; Catalase; Cells, Cultured; Enzyme Induction; Humans; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Microbodies; Mixed Function Oxygenases; Oxidation-Reduction; Palmitoyl Coenzyme A; Rats; Species Specificity; Trichloroacetic Acid; Trichloroethylene	1985